Documents in category 'Protein interactions' (reactome)

Cell regulation
score: 34.284857, Current Opinion in Cell Biology, 1996,

Pharmaceutical biotechnology
score: 24.689406, Current Opinion in Biotechnology, 1997,

Cell regulation
score: 24.312518, Current Opinion in Cell Biology, 1993,

Cell regulation
score: 20.931936, Current Opinion in Cell Biology, 1995,

Nucleus and gene expression
score: 19.550828, Current Opinion in Cell Biology, 1996,

Oncogenes and cell proliferation
score: 19.288145, Current Opinion in Genetics & Development, 1997,

Pharmaceutical biotechnology
score: 18.340315, Current Opinion in Biotechnology, 1995,

Bibliography of the current world literature
score: 17.972521, Current Opinion in Cell Biology, 1994,

Proteins
score: 16.767075, Current Opinion in Structural Biology, 1997,

Differentiation and gene regulation
score: 16.206526, Current Opinion in Genetics & Development, 1995,

Pharmaceutical biotechnology
score: 15.900528, Current Opinion in Biotechnology, 1994,

Differentiation and gene regulation
score: 14.457788, Current Opinion in Genetics & Development, 1996,

Bibliography of the current world literature
score: 14.282232, Current Opinion in Genetics & Development, 1993,

Nucleus and gene expression
score: 14.027002, Current Opinion in Cell Biology, 1997,

Nucleus and gene expression
score: 13.995199, Current Opinion in Cell Biology, 1995,

Proteins
score: 13.636685, Current Opinion in Structural Biology, 1996,

Lymphocyte activation and effector functions
score: 13.404606, Current Opinion in Immunology, 1996,

Gene expression and differentiation
score: 13.304387, Current Opinion in Genetics & Development, 1992,

Contents
score: 12.736925, Current Opinion in Biotechnology, 1996,

Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs.
score: 12.314228, Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 1999, Blalock, W L et. al.

A comprehensive map of the toll-like receptor signaling network.
score: 12.004241, Molecular systems biology, 2006, Oda, Kanae; Kitano, Hiroaki

Cell differentiation
score: 11.895797, Current Opinion in Cell Biology, 1994,

GrpL, a Grb2-related Adaptor Protein, Interacts with SLP-76 to Regulate Nuclear Factor of Activated T Cell Activation
score: 11.843241, The Journal of Experimental Medicine, 1999, Law, Che-Leung et. al.

Folding and binding
score: 11.511894, Current Opinion in Structural Biology, 1997,

Chromosomes and expression mechanisms
score: 11.475994, Current Opinion in Genetics & Development, 1995,

Lymphocyte activation and effector functions
score: 11.375021, Current Opinion in Immunology, 1997,

Somatostatin receptors
score: 11.372648, BBA - Biomembranes, 2003, Møller, Lars Neisig et. al.

Cell-to-cell contact and extracellular matrix
score: 11.124748, Current Opinion in Cell Biology, 1995,

A comprehensive map of the toll-like receptor signaling network
score: 10.929731, Molecular Systems Biology, 2006, Oda, Kanae; Kitano, Hiroaki

Mammalian genetics
score: 10.825357, Current Opinion in Genetics & Development, 1992,

Cell-to-cell contact and extracellular matrix
score: 10.67374, Current Opinion in Cell Biology, 1997,

Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins.
score: 10.658998, Pharmacological reviews, 1998, Aplin, A E; Howe, A; Alahari, S K; Juliano, R L

Chromosomes and expression mechanisms
score: 10.606188, Current Opinion in Genetics & Development, 1996,

Innate immunity
score: 10.340272, Current Opinion in Immunology, 1995,

Mammalian gene studies
score: 10.305744, Current Opinion in Biotechnology, 1992,

Regulatory and signaling properties of the Vav family.
score: 9.9805299, Molecular and cellular biology, 2000, Bustelo, X R

Mechanisms underlying differential responses to FGF signaling
score: 9.8588646, Cytokine and Growth Factor Reviews, 2005, Dailey, Lisa et. al.

Signal transduction pathways regulating the development of αβ T cells
score: 9.8515662, BBA - Reviews on Cancer, 1998, Farrar, Michael A; Doerfler, Petra; Sauer, Karsten

Role of the retinal vascular endothelial cell in ocular disease
score: 9.8360909, Progress in Retinal and Eye Research, 2013, Bharadwaj, Arpita S. et. al.

Many cuts to ruin: a comprehensive update of caspase substrates.
score: 9.8272685, Cell death and differentiation, 2003, Fischer, U; Jänicke, R U; Schulze-Osthoff, K

Both src-dependent and -independent mechanisms mediate phosphatidylinositol 3-kinase regulation of colony-stimulating factor 1-activated mitogen-activated protein kinases in myeloid progenitors.
score: 9.7983823, Molecular and cellular biology, 2000, Lee, A W; States, D J

Bibliography of the current world literature
score: 9.7784992, Current Opinion in Immunology, 1995,

Pharmaceutical applications
score: 9.5324687, Current Opinion in Biotechnology, 1992,

JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis.
score: 9.3294481, Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 2004, Steelman, L S et. al.

Molecular motors involved in T cell receptor clusterings.
score: 9.2757833, Journal of leukocyte biology, 2001, Krawczyk, C; Penninger, J M

Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.
score: 9.2179633, Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 2003, Chang, F et. al.

Signal transduction via the growth hormone receptor
score: 9.0836789, Cellular Signalling, 2001, Zhu, Tao et. al.

Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family
score: 9.062941, BBA - Molecular Cell Research, 2002, Martin, Michael U; Wesche, Holger

Structural determinants of SHP-2 function and specificity in Xenopus mesoderm induction.
score: 9.0471089, Molecular and cellular biology, 1998, O'Reilly, A M; Neel, B G

Antigen-Receptor Signaling to Nuclear Factor κB
score: 8.9341034, Immunity, 2006, Schulze-Luehrmann, Jan; Ghosh, Sankar

The Function of Small GTPases in Signaling by Immune Recognition and Other Leukocyte Receptors
score: 8.8575874, Advances in Immunology, 1999, Altman, Amnon; Deckert, Marcel

The SH2 domain: versatile signaling module and pharmaceutical target
score: 8.7949977, BBA - Proteins and Proteomics, 2005, Machida, Kazuya; Mayer, Bruce J.

Oncogenes and cell proliferation
score: 8.7693698, Current Opinion in Genetics & Development, 1994,

Expression systems
score: 8.7603792, Current Opinion in Biotechnology, 1997,

Innate Immunity
score: 8.726036, Current Opinion in Immunology, 1996,

A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin
score: 8.7175817, BBA - Molecular Cell Research, 2004, Willems, Andrew R.; Schwab, Michael; Tyers, Mike

Genomes and evolution
score: 8.6874896, Current Opinion in Genetics & Development, 1992,

Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages.
score: 8.640137, Molecular and cellular biology, 1998, Timms, J F et. al.

Coupling of Gab1 to C-Met, Grb2, and Shp2 Mediates Biological Responses
score: 8.601976, The Journal of Cell Biology, 2000, Schaeper, Ute et. al.

The c‐myc Promoter: Still MysterY and Challenge
score: 8.5958384, Advances in Cancer Research, 2008, Wierstra, Inken; Alves, Jürgen

Thec‐mycPromoter: Still MysterY and Challenge
score: 8.5958384, Advances in Cancer Research, 2008, Wierstra, Inken; Alves, Jürgen

Protein engineering
score: 8.4537271, Current Opinion in Biotechnology, 1997,

Signal characteristics of G protein-transactivated EGF receptor.
score: 8.3514621, The EMBO journal, 1997, Daub, H; Wallasch, C; Lankenau, A; Herrlich, A; Ullrich, A

Mechanisms of signaling by the hematopoietic-specific adaptor proteins, slp-76 and lat and their b cell counterpart, blnk/slp-65
score: 8.3248778, Advances in Immunology, 2001, Yablonski, Deborah; Weiss, Arthur

Mechanisms of signaling by the hematopoietic-specific adaptor proteins, slp-76 and lat and their b cell counterpart, blnk/slp-65
score: 8.3248778, Advances in Immunology, 2001, Yablonski, Deborah; Weiss, Arthur

SHP2-interacting Transmembrane Adaptor Protein (SIT), A Novel Disulfide-linked Dimer Regulating Human T Cell Activation
score: 8.297484, The Journal of Experimental Medicine, 1999, Marie-Cardine, Anne et. al.

Ligand-independent degradation of epidermal growth factor receptor involves receptor ubiquitylation and Hgs, an adaptor whose ubiquitin-interacting motif targets ubiquitylation by Nedd4.
score: 8.2580668, Traffic (Copenhagen, Denmark), 2002, Katz, Menachem et. al.

Molecular interactions of SHP1 and SHP2 in IL-3-signalling
score: 8.2096038, Cellular Signalling, 2002, Wheadon, Helen; Paling, Nicholas R.D.; Welham, Melanie J.

28th Annual Meeting International Society for Experimental Hematology
score: 8.2083168, Experimental Hematology, 1999,

Pharmacological aspects of targeting cancer gene therapy to endothelial cells
score: 8.1406561, Critical Reviews in Oncology and Hematology, 2001, Sedlacek, H.H.

SHC and SHIP phosphorylation and interaction in response to activation of the FLT3 receptor.
score: 8.1346147, Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 1999, Marchetto, S et. al.

Proteins
score: 8.116627, Current Opinion in Structural Biology, 1995,

Signal Transduction Pathways That Regulate the Fate of B Lymphocytes
score: 8.0960677, Advances in Immunology, 1999, Craxton, Andrew et. al.

Cell regulation
score: 8.0935107, Current Opinion in Cell Biology, 1990,

Signal Transduction Pathways That Regulate the Fate of B Lymphocytes
score: 8.0709496, Advances in Immunology, 1999, Craxton, Andrew et. al.

Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.
score: 8.051364, Molecular and cellular biology, 2011, Clement, Sandra L et. al.

Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex
score: 8.0322261, Pharmacology and Therapeutics, 2003, Fujihara, Mitsuhiro et. al.

Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A.
score: 8.0083137, Molecular and cellular biology, 2008, Aranda, Sergi et. al.

The Function of Small GTPases in Signaling by Immune Recognition and Other Leukocyte Receptors
score: 7.9854325, Advances in Immunology, 1999, Altman, Amnon; Deckert, Marcel

Microbes and their products—physiological effects upon mammalian mucosa
score: 7.9472532, Advanced Drug Delivery Reviews, 2004, Viswanathan, V.K; Sharma, Rachna; Hecht, Gail

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway.
score: 7.9389534, The EMBO journal, 2001, Hocevar, B A; Smine, A; Xu, X X; Howe, P H

Ligand screening system using fusion proteins of G protein-coupled receptors with G protein α subunits
score: 7.9206879, Neurochemistry International, 2007, Suga, Hinako; Haga, Tatsuya

Activation of Syk protein tyrosine kinase in response to osmotic stress requires interaction with p21-activated protein kinase Pak2/gamma-PAK.
score: 7.8888438, Molecular and cellular biology, 2004, Miah, S M Shahjahan et. al.

Direct binding of Grb2 SH3 domain to FGFR2 regulates SHP2 function
score: 7.8260606, Cellular Signalling, 2010, Ahmed, Zamal et. al.

Protein tyrosine kinase regulation by ubiquitination: Critical roles of Cbl-family ubiquitin ligases
score: 7.8218084, BBA - Molecular Cell Research, 2013, Mohapatra, Bhopal et. al.

Protein tyrosine kinase regulation by ubiquitination: Critical roles of Cbl-family ubiquitin ligases
score: 7.8218084, BBA - Molecular Cell Research, 2013, Mohapatra, Bhopal et. al.

Functional analysis of RalGPS2, a murine guanine nucleotide exchange factor for RalA GTPase
score: 7.7429032, Experimental Cell Research, 2007, Ceriani, Michela et. al.

Shared Principles in NF-κB Signaling
score: 7.7193894, Cell, 2008, Hayden, Matthew S.; Ghosh, Sankar

BNIP-2 induces cell elongation and membrane protrusions by interacting with Cdc42 via a unique Cdc42-binding motif within its BNIP-2 and Cdc42GAP homology domain
score: 7.678987, Experimental Cell Research, 2005, Zhou, Yi Ting; Guy, Graeme R.; Low, Boon Chuan

Identification of Potential Drug Targets Using Genomics and Proteomics: A Systems Approach
score: 7.6782796, Advances in Pharmacology, 2008, Klase, Zachary A.; Duyne, Rachel Van; Kashanchi, Fatah

Identification of Potential Drug Targets Using Genomics and Proteomics: A Systems Approach
score: 7.6782796, Advances in Pharmacology, 2008, Klase, Zachary A.; Duyne, Rachel Van; Kashanchi, Fatah

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides
score: 7.6688804, Current Biology, 1995, van der Geer, Peter et. al.

Induced direct binding of the adapter protein Nck to the GTPase-activating protein-associated protein p62 by epidermal growth factor.
score: 7.6642748, Oncogene, 1997, Tang, J; Feng, G S; Li, W

The role of VEGF receptors in angiogenesis; complex partnerships
score: 7.5960522, Cellular and Molecular Life Sciences , 2006, Cébe-Suarez, S.; Zehnder-Fjällman, A.; Ballmer-Hofer, K.

The secret life of kinases: functions beyond catalysis
score: 7.5827874, Cell Communication and Signaling : CCS, 2011, Rauch, Jens; Volinsky, Natalia; Romano, David; Kolch, Walter

Nucleus and gene expression
score: 7.5715452, Current Opinion in Cell Biology, 1994,

Chromosomes and expression mechanisms
score: 7.489405, Current Opinion in Genetics & Development, 1997,

Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates.
score: 7.4615626, The EMBO journal, 2008, Ng, Cherlyn et. al.

Contact-dependent signaling during the late events of platelet activation.
score: 7.4593098, Journal of thrombosis and haemostasis : JTH, 2003, Prevost, N; Woulfe, D; Tognolini, M; Brass, L F

β1 integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation
score: 7.4484751, The Journal of Cell Biology, 2005, Defilippi, Paola et. al.

Expression systems
score: 7.4441412, Current Opinion in Biotechnology, 1994,

Cloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cells.
score: 7.373186, Oncogene, 1999, Schmandt, R; Liu, S K; McGlade, C J

Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins
score: 7.362121, The Journal of Cell Biology, 2001, Mechtersheimer, Sabine et. al.

Pathogen Recognition and Innate Immunity
score: 7.3602743, Cell, 2006, Akira, Shizuo; Uematsu, Satoshi; Takeuchi, Osamu

Cell-to-cell contact and extracellular matrix
score: 7.3587039, Current Opinion in Cell Biology, 1993,

Paired inhibitory and triggering NK cell receptors for HLA class I molecules
score: 7.3415808, Human Immunology, 2000, López-Botet, Miguel et. al.

Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses.
score: 7.3385669, Oncogene, 2006, Hiscott, J; Nguyen, T-L A; Arguello, M; Nakhaei, P; Paz, S

Ubiquitin Ligase Activity and Tyrosine Phosphorylation Underlie Suppression of Growth Factor Signaling by c-Cbl/Sli-1
score: 7.3318356, Molecular Cell, 1999, Levkowitz, Gil et. al.

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures.
score: 7.3195439, The Journal of general virology, 2008, Randall, Richard E; Goodbourn, Stephen

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides
score: 7.3103537, Current Biology, 1995, van der Geer, Peter et. al.

Grb2 and the Non-T Cell Activation Linker NTAL Constitute a Ca 2+-Regulating Signal Circuit in B Lymphocytes
score: 7.3037215, Immunity, 2004, Stork, Björn et. al.

dsRNA-Dependent Protein Kinase PKR and its Role in Stress, Signaling and HCV Infection
score: 7.2841546, Viruses, 2012, Dabo, Stéphanie; Meurs, Eliane F.

Chromosomes and expression mechanisms
score: 7.2807397, Current Opinion in Genetics & Development, 1994,

Regulation of Protease and Protease Inhibitor Gene Expression: The Role of the 3′‐UTR and Lessons from the Plasminogen Activating System
score: 7.2633831, Progress in Nucleic Acid Research and Molecular Biology, 2005, Stasinopoulos, Stan et. al.

Extended-Synaptotagmin-2 Mediates FGF Receptor Endocytosis and ERK Activation In Vivo
score: 7.2255803, Developmental Cell, 2010, Jean, Steve et. al.

Extended-Synaptotagmin-2 Mediates FGF Receptor Endocytosis and ERK Activation In Vivo
score: 7.2255803, Developmental Cell, 2010, Jean, Steve et. al.

Regulation of Protease and Protease Inhibitor Gene Expression: The Role of the 3′‐UTR and Lessons from the Plasminogen Activating System
score: 7.2151412, Progress in Nucleic Acid Research and Molecular Biology, 2005, Stasinopoulos, Stan et. al.

Phosphorylation of Human Tristetraprolin in Response to Its Interaction with the Cbl Interacting Protein CIN85
score: 7.1959116, PLoS ONE, 2010, Kedar, Vishram P. et. al.

Syk and pTyr'd: Signaling through the B cell antigen receptor
score: 7.1928714, BBA - Molecular Cell Research, 2009, Geahlen, Robert L.

Relations between the mitogen-activated protein kinase and the cAMP-dependent protein kinase pathways: Comradeship and hostility
score: 7.1676594, Cellular Signalling, 2008, Gerits, Nancy et. al.

Receptor tyrosine kinases and their targets
score: 7.1383732, Current Opinion in Genetics & Development, 1994, Kazlauskas, Andrius

Factors controlling axonal and dendritic arbors
score: 7.1225096, International Review of Cytology, 2001, Keith, Charles H.; Wilson, Mark T.

Factors controlling axonal and dendritic arbors
score: 7.1225096, International Review of Cytology, 2001, Keith, Charles H.; Wilson, Mark T.

Factors controlling axonal and dendritic arbors
score: 7.1225096, International Review of Cytology, 2001, Keith, Charles H.; Wilson, Mark T.

Specificity in Signal Transduction
score: 7.0826901, Cell, 2004, Pawson, Tony

T Cell Receptor (TCR)-induced Tyrosine Phosphorylation Dynamics Identifies THEMIS as a New TCR Signalosome Component *
score: 7.0699909, The Journal of Biological Chemistry, 2010, Brockmeyer, Claudia et. al.

Role of Immunoreceptor Tyrosine-Based Activation Motif in Signal Transduction from Antigen and Fc Receptors
score: 7.0671987, Advances in Immunology, 1998, Isakov, Noah

Notch regulation of early thymocyte development
score: 7.0611774, Seminars in Immunology, 2010, Yashiro-Ohtani, Yumi; Ohtani, Takuya; Pear, Warren S.

Pathogen recognition and inflammatory signaling in innate immune defenses.
score: 6.9256452, Clinical microbiology reviews, 2009, Mogensen, Trine H

Membrane proteins
score: 6.912091, Current Opinion in Structural Biology, 1997,

The proteasomal system
score: 6.9034838, Molecular Aspects of Medicine, 2009, Jung, Tobias; Catalgol, Betül; Grune, Tilman

Disruption of SLP-76 interaction with Gads inhibits dynamic clustering of SLP-76 and FcepsilonRI signaling in mast cells.
score: 6.8817601, Molecular and cellular biology, 2006, Silverman, Michael A et. al.

LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation.
score: 6.8784408, The EMBO journal, 2004, Gur, Gal et. al.

Delivery of bioactive molecules into the cell: the Trojan horse approach
score: 6.8747807, Molecular and Cellular Neuroscience, 2004, Dietz, Gunnar P.H.; Bδhr, Mathias

Genetics of disease
score: 6.8701676, Current Opinion in Genetics & Development, 1997,

Involvement of platelet-derived growth factor in disease: development of specific antagonists
score: 6.8622429, Advances in Cancer Research, 2001, Östman, Arne; Heldin, Carl-Henrik

Involvement of platelet-derived growth factor in disease: development of specific antagonists
score: 6.8622429, Advances in Cancer Research, 2001, Östman, Arne; Heldin, Carl-Henrik

Involvement of platelet-derived growth factor in disease: development of specific antagonists
score: 6.8622429, Advances in Cancer Research, 2001, Östman, Arne; Heldin, Carl-Henrik

Bibliography of the current world literature
score: 6.8615528, Current Opinion in Neurobiology, 1993,

Role of Immunoreceptor Tyrosine-Based Activation Motif in Signal Transduction from Antigen and Fc Receptors
score: 6.8385903, Advances in Immunology, 1998, Isakov, Noah

Asymmetrical phosphorylation and function of immunoreceptor tyrosine-based activation motif tyrosines in B cell antigen receptor signal transduction.
score: 6.8241936, Journal of immunology (Baltimore, Md. : 1950), 1998, Pao, L I; Famiglietti, S J; Cambier, J C

G-protein signaling: back to the future
score: 6.792749, Cellular and Molecular Life Sciences , 2005, McCudden, C. R. et. al.

A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways.
score: 6.7837873, EMBO reports, 2005, Krappmann, Daniel; Scheidereit, Claus

Mammalian gene studies
score: 6.7771198, Current Opinion in Biotechnology, 1993,

B cell antigen receptor (BCR)-mediated formation of a SHP-2-pp120 complex and its inhibition by Fc gamma RIIB1-BCR coligation.
score: 6.7655987, Journal of immunology (Baltimore, Md. : 1950), 1998, Nakamura, K; Cambier, J C

Adapter proteins in lymphocyte antigen-receptor signaling
score: 6.7580075, Current Opinion in Immunology, 2000, Myung, Peggy S; Boerthe, Nancy J; Koretzky, Gary A

Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling.
score: 6.7137628, Nature structural & molecular biology, 2004, Sarkar, Saumendra N et. al.

TNF receptor subtype signalling: Differences and cellular consequences
score: 6.7093565, Cellular Signalling, 2002, MacEwan, David J.

AKT/PKB Signaling: Navigating Downstream
score: 6.7018745, Cell, 2007, Manning, Brendan D.; Cantley, Lewis C.

Ubiquitin-binding domains and their role in the DNA damage response
score: 6.6984413, DNA Repair, 2009, Hofmann, Kay

Nucleus and gene expression
score: 6.6914116, Current Opinion in Cell Biology, 1993,

Identification of XDRP1; a Xenopus protein related to yeast Dsk2p binds to the N-terminus of cyclin A and inhibits its degradation.
score: 6.6832496, The EMBO journal, 1999, Funakoshi, M; Geley, S; Hunt, T; Nishimoto, T; Kobayashi, H

Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation.
score: 6.6778176, Oncogene, 1997, Yokouchi, M et. al.

Involvement of JAK-family tyrosine kinases in hematopoietin receptor signal transduction
score: 6.6739182, Progress in Growth Factor Research, 1994, Kirken, Robert A. et. al.

Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav.
score: 6.6621099, Molecular and cellular biology, 2011, Chen, Chih-Hong et. al.

Current Views in Intracellular Transport: Insights from Studies in Immunology
score: 6.6586569, Advances in Immunology, 1998, Hsu, Victor W.; Peters, Peter J.

Fibroblast growth factor receptor-induced phosphorylation of STAT1 at the Golgi apparatus without translocation to the nucleus.
score: 6.6565393, Journal of cellular physiology, 2007, Citores, Lucía; Bai, Ling; Sørensen, Vigdis; Olsnes, Sjur

Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc.
score: 6.6429691, British journal of cancer, 2002, Roccato, E et. al.

Missing Pieces in the NF-κB Puzzle
score: 6.6078275, Cell, 2002, Ghosh, Sankar; Karin, Michael

Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells.
score: 6.606687, Proceedings of the National Academy of Sciences of the United States of America, 1998, Herrlich, A et. al.

Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk
score: 6.5872634, BBA - Molecular Cell Research, 1997, Furlong, Michael T et. al.

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription.
score: 6.5604825, Oncogene, 2006, Scheidereit, Claus

LINE-1 ORF1 protein localizes in stress granules with other RNA-binding proteins, including components of RNA interference RNA-induced silencing complex.
score: 6.5410876, Molecular and cellular biology, 2007, Goodier, John L et. al.

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family.
score: 6.5309718, Pharmacological reviews, 2009, Ye, Richard D et. al.

The Next Wave
score: 6.5309067, Cellular Signalling, 1999, Mustelin, Tomas et. al.

Involvement of Phospholipase Cγ1 in Mouse Egg Activation Induced by a Truncated Form of the C-kit Tyrosine Kinase Present in Spermatozoa
score: 6.5305473, The Journal of Cell Biology, 1998, Sette, Claudio et. al.

Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers.
score: 6.529966, Molecular and cellular biology, 1999, Muthuswamy, S K; Gilman, M; Brugge, J S

Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import.
score: 6.5227991, Journal of immunology (Baltimore, Md. : 1950), 2004, Mattioli, Ivan et. al.

The molecular understanding of osteoclast differentiation
score: 6.5218493, Bone, 2007, Asagiri, Masataka; Takayanagi, Hiroshi

Chapter 4 Adhesion Proteins Meet Receptors
score: 6.5197115, Advances in Cancer Research, 2008, Orian‐Rousseau, Véronique; Ponta, Helmut

Chapter 4 Adhesion Proteins Meet Receptors:A Common Theme?
score: 6.5197115, Advances in Cancer Research, 2008, Orian‐Rousseau, Véronique; Ponta, Helmut

Human B Lymphocytes: Phenotype, Proliferation, and Differentiation
score: 6.5152602, Advances in Immunology, 1992, Banchereau, Jacques; Rousset, Françoise

Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase.
score: 6.5112259, Molecular and cellular biology, 1993, Pleiman, C M et. al.

FGFs in endochondral skeletal development.
score: 6.5090751, Journal of cellular biochemistry, 2010, Degnin, Catherine R; Laederich, Melanie B; Horton, William A

Cell differentiation
score: 6.5021074, Current Opinion in Cell Biology, 1996,

Platelet adhesion signalling and the regulation of thrombus formation.
score: 6.4912108, Journal of cell science, 2004, Gibbins, Jonathan M

Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2
score: 6.4767703, Current Biology, 1996, Kavanaugh, W.M. et. al.

NK cell activation: distinct stimulatory pathways counterbalancing inhibitory signals
score: 6.4650056, Human Immunology, 2000, Bakker, Alexander B.H et. al.

The protein-tyrosine kinase Syk interacts with the C-terminal region of tensin2
score: 6.4531859, BBA - Molecular Cell Research, 2012, Moon, Kyung D. et. al.

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
score: 6.4426178, Cell, 2009, Kopan, Raphael; Ilagan, Ma. Xenia G.

No one can whistle a symphony alone - how different ubiquitin linkages cooperate to orchestrate NF-κB activity.
score: 6.439453, Journal of cell science, 2012, Schmukle, Anna C; Walczak, Henning

The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO molecules.
score: 6.4265387, Journal of immunology (Baltimore, Md. : 1950), 1998, Hammond, C et. al.

Fes mediates the IL-4 activation of insulin receptor substrate-2 and cellular proliferation.
score: 6.4243727, Journal of immunology (Baltimore, Md. : 1950), 2001, Jiang, H et. al.

Bibliography of the current world literature
score: 6.4236144, Current Opinion in Cell Biology, 1990,

Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells.
score: 6.4138699, The EMBO journal, 2011, Sela, Meirav et. al.

Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors
score: 6.4125614, The Journal of Cell Biology, 2004, Arthur, William T. et. al.

The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation
score: 6.3812423, Cellular Signalling, 2004, Dean, Jonathan L.E et. al.

The SLP-76 family of adapter proteins
score: 6.3737259, Seminars in Immunology, 2004, Wu, Jennifer N.; Koretzky, Gary A.

Protein tyrosine kinases Syk and ZAP-70 display distinct requirements for Src family kinases in immune response receptor signal transduction.
score: 6.3696342, Journal of immunology (Baltimore, Md. : 1950), 1997, Zoller, K E; MacNeil, I A; Brugge, J S

NF-kappaB activation pathways induced by T cell costimulation.
score: 6.3692684, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Schmitz, M Lienhard; Bacher, Susanne; Dienz, Oliver

Pattern Recognition Receptors and Inflammation
score: 6.3662607, Cell, 2010, Takeuchi, Osamu; Akira, Shizuo

Regulation of nuclear import and export by the GTPase ran
score: 6.3567563, International Review of Cytology, 2002, Steggerda, Susanne M.; Paschal, Bryce M.

RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix.
score: 6.3557874, Molecular and cellular biology, 2002, Hermanto, Ulrich; Zong, Cong S; Li, Weiqun; Wang, Lu-Hai

Differentiation therapy of human cancer: basic science and clinical applications
score: 6.3546788, Pharmacology and Therapeutics, 2001, Leszczyniecka, Magdalena et. al.

Inhibition of angiogenesis by growth factor receptor bound protein 2-Src homology 2 domain bound antagonists.
score: 6.3530141, Molecular cancer therapeutics, 2004, Soriano, Jesus V et. al.

Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin
score: 6.3468286, BMC Neuroscience, 2005, Hartwig, Christine et. al.

Contents
score: 6.3322417, Current Opinion in Genetics & Development, 1995,

Nck adapter proteins: functional versatility in T cells
score: 6.3310753, Cell Communication and Signaling : CCS, 2009, Lettau, Marcus; Pieper, Jennifer; Janssen, Ottmar

LPS induction of gene expression in human monocytes
score: 6.3123039, Cellular Signalling, 2001, Guha, Mausumee; Mackman, Nigel

Receptor tyrosine kinases: mechanisms of activation and signaling
score: 6.3113421, Current Opinion in Cell Biology, 2007, Hubbard, Stevan R; Miller, W Todd

BASH, a novel signaling molecule preferentially expressed in B cells of the bursa of Fabricius.
score: 6.3090288, Journal of immunology (Baltimore, Md. : 1950), 1998, Goitsuka, R et. al.

Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation.
score: 6.3069355, Traffic (Copenhagen, Denmark), 2003, Jiang, Xuejun; Sorkin, Alexander

Bibliography of the current world literature
score: 6.2981611, Current Opinion in Cell Biology, 1991,

Nonproteolytic Functions of Ubiquitin in Cell Signaling
score: 6.2970816, Molecular Cell, 2009, Chen, Zhijian J.; Sun, Lijun J.

Biologic Functions and Signaling of the Interleukin-4 Receptor Complexes
score: 6.2947962, Immunobiology, 2000, Gessner, André; Röllinghoff, Martin

Human B Lymphocytes: Phenotype, Proliferation, and Differentiation
score: 6.2866519, Advances in Immunology, 1992, Banchereau, Jacques; Rousset, Françoise

SHPS-1 induces aggregation of Ba/F3 pro-B cells via an interaction with CD47.
score: 6.2711394, Journal of immunology (Baltimore, Md. : 1950), 2000, Babic, I; Schallhorn, A; Lindberg, F P; Jirik, F R

Current bibliography of Cell Calcium prepared by the University of Sheffield Biomedical Information Service
score: 6.2700444, Cell Calcium, 1992,

BCAP
score: 6.2654395, Immunity, 2000, Okada, Takaharu et. al.

Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation.
score: 6.264962, Proceedings of the National Academy of Sciences of the United States of America, 1995, Gurney, A L; Wong, S C; Henzel, W J; de Sauvage, F J

The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase.
score: 6.2593862, Molecular and cellular biology, 2000, Genot, E M et. al.

EGF-ERBB signalling: towards the systems level.
score: 6.2568324, Nature reviews. Molecular cell biology, 2006, Citri, Ami; Yarden, Yosef

Regulation of axonal outgrowth and pathfinding by integrin-ECM interactions.
score: 6.2568184, Developmental neurobiology, 2011, Myers, Jonathan P; Santiago-Medina, Miguel; Gomez, Timothy M

Akt is negatively regulated by the MULAN E3 ligase.
score: 6.2511498, Cell research, 2012, Bae, Seunghee et. al.

Toll-like receptors: From the discovery of NFκB to new insights into transcriptional regulations in innate immunity
score: 6.2464336, Biochemical Pharmacology, 2006, Doyle, Sarah L.; O’Neill, Luke A.J.

Protein engineering
score: 6.2440655, Current Opinion in Biotechnology, 1995,

B Cell Adaptor Containing Src Homology 2 Domain (Bash) Links B Cell Receptor Signaling to the Activation of Hematopoietic Progenitor Kinase 1
score: 6.2371139, The Journal of Experimental Medicine, 2001, Tsuji, Sachiyo et. al.

ERK1/2 MAP kinases: Structure, function, and regulation
score: 6.2355664, Pharmacological Research, 2012, Roskoski, Robert

Intracellular single-chain variable fragments directed to the Src homology 2 domains of Syk partially inhibit Fc epsilon RI signaling in the RBL-2H3 cell line.
score: 6.2290768, Journal of immunology (Baltimore, Md. : 1950), 2002, Dauvillier, Stéphanie et. al.

Grb10/Nedd4-mediated multiubiquitination of the insulin-like growth factor receptor regulates receptor internalization.
score: 6.211636, Journal of cellular physiology, 2008, Monami, Giada; Emiliozzi, Velia; Morrione, Andrea

IκB Kinase {varepsilon}-Dependent Phosphorylation and Degradation of X-Linked Inhibitor of Apoptosis Sensitizes Cells to Virus-Induced Apoptosis.
score: 6.1916132, Journal of virology, 2012, Nakhaei, Peyman et. al.

Chapter 5 Translational Control of Gene Expression
score: 6.1893909, International Review of Cell and Molecular Biology, 2008, Lackner, Daniel H.; Bähler, Jürg

Chapter 5 Translational Control of Gene Expression:From Transcripts to Transcriptomes
score: 6.1893909, International Review of Cell and Molecular Biology, 2008, Lackner, Daniel H.; Bähler, Jürg

IL-2 receptor signaling through the Shb adapter protein in T and NK cells
score: 6.1873348, Biochemical and Biophysical Research Communications, 2002, Lindholm, Cecilia K

Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily.
score: 6.1684427, Developmental dynamics : an official publication of the American Association of Anatomists, 2000, Crossin, K L; Krushel, L A

Mechanistic Insights into Notch Receptor Signaling from Structural and Biochemical Studies
score: 6.1616932, Current Topics in Developmental Biology, 2010, Kovall, Rhett A.; Blacklow, Stephen C.

The noncatalytic domains of Lck regulate its dephosphorylation by CD45
score: 6.1573185, BBA - Proteins and Proteomics, 2003, Lefebvre, Dennis C. et. al.

The anaphase-promoting complex: a key factor in the regulation of cell cycle.
score: 6.1541008, Oncogene, 2005, Castro, Anna et. al.

Compartmentalization of ITAM and integrin signaling by adapter molecules.
score: 6.149638, Immunological reviews, 2007, Bezman, Natalie; Koretzky, Gary A

Src homology region 2 domain-containing phosphatase 1 positively regulates B cell receptor-induced apoptosis by modulating association of B cell linker protein with Nck and activation of c-Jun NH2-terminal kinase.
score: 6.1451485, Journal of immunology (Baltimore, Md. : 1950), 2002, Mizuno, Kazuya et. al.

Inhibition of signaling through the B cell antigen receptor by the protooncogene product, c-Cbl, requires Syk tyrosine 317 and the c-Cbl phosphotyrosine-binding domain.
score: 6.1374802, Journal of immunology (Baltimore, Md. : 1950), 1999, Yankee, T M et. al.

Physiological requirement for both SH2 domains for phospholipase C-gamma1 function and interaction with platelet-derived growth factor receptors.
score: 6.1283871, Molecular and cellular biology, 1999, Ji, Q S; Chattopadhyay, A; Vecchi, M; Carpenter, G

L1 Cell Adhesion Molecule Signal Cascades: Targets for Ethanol Developmental Neurotoxicity
score: 6.1240782, Neurotoxicology, 2001, Bearer, Cynthia F

Protein engineering
score: 6.122261, Current Opinion in Biotechnology, 1994,

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
score: 6.1183874, Cell, 1993, Witthuhn, Bruce A. et. al.

Oncogenes and cell proliferation
score: 6.1182524, Current Opinion in Genetics & Development, 1993,

Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2
score: 6.1182435, Current Biology, 1996, Kavanaugh, W.M. et. al.

Human cytomegalovirus envelope glycoproteins B and H are necessary for TLR2 activation in permissive cells.
score: 6.1160798, Journal of immunology (Baltimore, Md. : 1950), 2006, Boehme, Karl W; Guerrero, Mario; Compton, Teresa

The TNF-receptor-associated factor family
score: 6.1127716, Cellular Signalling, 2001, Wajant, Harald; Henkler, Frank; Scheurich, Peter

The insulin receptor and type I IGF receptor: Comparison of structure and function
score: 6.1046392, Progress in Growth Factor Research, 1992, Siddle, Kenneth

CD16-mediated activation of phosphatidylinositol-3 kinase (PI-3K) in human NK cells involves tyrosine phosphorylation of Cbl and its association with Grb2, Shc, pp36 and p85 PI-3K subunit.
score: 6.1039834, European journal of immunology, 1998, Cerboni, C et. al.

Genetic analysis of protein tyrosine phosphatases
score: 6.0921758, Current Opinion in Genetics & Development, 1998, Van Vactor, David; O'Reilly, Alana M; Neel, Benjamin G

The biogenesis of the MHC class II compartment in human I-cell disease B lymphoblasts
score: 6.0820052, The Journal of Cell Biology, 1996,

The von Hippel–Lindau protein, HIF hydroxylation, and oxygen sensing
score: 6.0793377, Biochemical and Biophysical Research Communications, 2005, Kaelin, William G.

Sprouty 2 disturbs FGFR3 degradation in thanatophoric dysplasia type II: A severe form of human achondroplasia
score: 6.0755859, Cellular Signalling, 2008, Guo, Changsheng et. al.

Direct binding and In vivo regulation of the fission yeast p21-activated kinase shk1 by the SH3 domain protein scd2.
score: 6.0404542, Molecular and cellular biology, 1999, Chang, E et. al.

Signaling via Vascular Endothelial Growth Factor Receptors
score: 6.0383708, Experimental Cell Research, 1999, Petrova, Tatiana V.; Makinen, Taija; Alitalo, Kari

Free major histocompatibility complex class I heavy chain is preferentially targeted for degradation by human T-cell leukemia/lymphotropic virus type 1 p12(I) protein.
score: 6.0371309, Journal of virology, 2001, Johnson, J M et. al.

Intermolecular interactions of Sprouty proteins and their implications in development and disease.
score: 6.034116, Molecular pharmacology, 2009, Edwin, Francis et. al.

Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site.
score: 6.0288893, Oncogene, 1997, Braunger, J et. al.

Mechanism of activation for Zap-70 catalytic activity.
score: 6.0228083, Proceedings of the National Academy of Sciences of the United States of America, 1996, LoGrasso, P V et. al.

Bibliography of the current world literature
score: 6.0201004, Current Opinion in Cell Biology, 1993,

Index to volume 52.
score: 6.0178592, Cancer research, 1992,

The Sar1 Gtpase Coordinates Biosynthetic Cargo Selection with Endoplasmic Reticulum Export Site Assembly
score: 6.0008335, The Journal of Cell Biology, 2001, Aridor, Meir et. al.

Ras and its effectors
score: 5.9926204, Progress in Biophysics and Molecular Biology, 1996, Herrmann, Christian; Nassar, Nicolas

Linear polyubiquitination: a new regulator of NF-kappaB activation.
score: 5.9920704, EMBO reports, 2009, Iwai, Kazuhiro; Tokunaga, Fuminori

The FGF family: biology, pathophysiology and therapy.
score: 5.9868114, Nature reviews. Drug discovery, 2009, Beenken, Andrew; Mohammadi, Moosa

Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc
score: 5.9781729, British Journal of Cancer, 2002, Roccato, E et. al.

Phosphorylation of FADD/MORT1 and Fas by kinases that associate with the membrane-proximal cytoplasmic domain of Fas.
score: 5.9663004, Journal of immunology (Baltimore, Md. : 1950), 1998, Kennedy, N J; Budd, R C

Drosophila Nedd4, a Ubiquitin Ligase, Is Recruited by Commissureless to Control Cell Surface Levels of the Roundabout Receptor
score: 5.9549465, Neuron, 2002, Myat, Anna et. al.

Sprouty 2 binds ESCRT-II factor Eap20 and facilitates HIV-1 gag release.
score: 5.9518718, Journal of virology, 2011, Medina, G N et. al.

The lymphoid protein tyrosine phosphatase Lyp interacts with the adaptor molecule Grb2 and functions as a negative regulator of T-cell activation
score: 5.9442464, Experimental Hematology, 2002, Hill, Ronald J et. al.

Vascular derived growth factors: cell biology, pathophysiology, and pharmacology.
score: 5.9437397, Pharmacological reviews, 1993, Bobik, A; Campbell, J H

Fibronectin: a multidomain host adhesin targeted by bacterial fibronectin-binding proteins.
score: 5.9427071, FEMS microbiology reviews, 2011, Henderson, Brian et. al.

Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells.
score: 5.9403052, Proceedings of the National Academy of Sciences of the United States of America, 2009, Brenner, Dirk et. al.

Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases.
score: 5.9392548, Molecular and cellular biology, 2000, Winberg, G et. al.

Regulation of MAPKs by growth factors and receptor tyrosine kinases
score: 5.9328009, BBA - Molecular Cell Research, 2007, Katz, Menachem; Amit, Ido; Yarden, Yosef

Yersinia outer protein P suppresses TGF-beta-activated kinase-1 activity to impair innate immune signaling in Yersinia enterocolitica-infected cells.
score: 5.9267079, Journal of immunology (Baltimore, Md. : 1950), 2005, Haase, Rudolf et. al.

Anatomy of a murder—signal transduction pathways leading to activation of natural killer cells
score: 5.9225439, Immunology Letters, 2005, Zompi, S.; Colucci, F.

The Vav Binding Site (Y315) in ZAP-70 Is Critical for Antigen Receptor–mediated Signal Transduction
score: 5.8976539, The Journal of Experimental Medicine, 1997, Wu, Jun; Zhao, Qihong; Kurosaki, Tomohiro; Weiss, Arthur

Spatial organization of signal transduction molecules in the NK cell immune synapses during MHC class I-regulated noncytolytic and cytolytic interactions.
score: 5.8957693, Journal of immunology (Baltimore, Md. : 1950), 2001, Vyas, Y M et. al.

A Role for Abl in Notch Signaling
score: 5.8909286, Neuron, 1998, Giniger, Edward

The adaptor function of SHP-2 downstream of the prolactin receptor is required for the recruitment of p29, a substrate of SHP-2
score: 5.8885809, Cellular Signalling, 2003, Minoo, Parham et. al.

Tumor necrosis factor receptor-associated factors (TRAFs).
score: 5.8858394, Oncogene, 2001, Bradley, J R; Pober, J S

The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development.
score: 5.869571, The EMBO journal, 2008, Kulathu, Yogesh et. al.

Mutant G-protein-coupled receptors as a cause of human diseases
score: 5.8692942, Pharmacology and Therapeutics, 2004, Schöneberg, Torsten et. al.

Fluorescence/bioluminescence resonance energy transfer techniques to study G-protein-coupled receptor activation and signaling.
score: 5.8619456, Pharmacological reviews, 2012, Lohse, Martin J; Nuber, Susanne; Hoffmann, Carsten

Regulation of chemotaxis by the orchestrated activation of Ras, PI3K, and TOR
score: 5.8486583, European Journal of Cell Biology, 2006, Sasaki, Atsuo T.; Firtel, Richard A.

Role of subunit diversity in signaling by heterotrimeric G proteins
score: 5.8469479, Biochemical Pharmacology, 1997, Hildebrandt, John D.

The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity.
score: 5.8456554, The FEBS journal, 2012, Sents, Ward et. al.

Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function
score: 5.8418197, Pharmacology and Therapeutics, 2004, Kristiansen, Kurt

Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases
score: 5.8380853, Cell, 1994, Cheng, Hwai-Jong; Flanagan, John G.

The role of Rho GTPases and associated kinases in regulating neurite outgrowth
score: 5.8372217, International Journal of Biochemistry and Cell Biology, 2002, Nikolic, Margareta

The IKK Kinases: Operators of Antiviral Signaling
score: 5.8346147, Viruses, 2010, Pham, Alissa M.; tenOever, Benjamin R.

Non-canonical fibroblast growth factor signalling in angiogenesis.
score: 5.8331928, Cardiovascular research, 2008, Murakami, Masahiro; Elfenbein, Arye; Simons, Michael

Notch inhibition of E47 supports the existence of a novel signaling pathway.
score: 5.8330271, Molecular and cellular biology, 1998, Ordentlich, P et. al.

SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome.
score: 5.8313442, Molecular and cellular biology, 2004, Vuong, Bao Q et. al.

Suppressors of cytokine signaling (SOCS) 1 and SOCS3 interact with and modulate fibroblast growth factor receptor signaling.
score: 5.8286597, Journal of cell science, 2006, Ben-Zvi, Tal et. al.

Fibroblast growth factor receptor 2 phosphorylation on serine 779 couples to 14-3-3 and regulates cell survival and proliferation.
score: 5.8202169, Molecular and cellular biology, 2008, Lonic, Ana et. al.

The Xenopus Chk1 Protein Kinase Mediates a Caffeine-sensitive Pathway of Checkpoint Control in Cell-free Extracts
score: 5.8001424, The Journal of Cell Biology, 1998, Kumagai, Akiko et. al.

Activation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascade.
score: 5.7955268, Oncogene, 2002, Pratt, Rebecca L; Kinch, Michael S

c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.
score: 5.7869584, Journal of cell science, 2004, de Melker, Annemieke A; van der Horst, Gerda; Borst, Jannie

Bibliography of the current world literature
score: 5.782452, Current Opinion in Neurobiology, 1992,

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain.
score: 5.778837, The EMBO journal, 1997, Su, Y C; Han, J; Xu, S; Cobb, M; Skolnik, E Y

Deciphering the pathway from the TCR to NF-kappaB.
score: 5.7771885, Cell death and differentiation, 2006, Weil, R; Israël, A

Expression of mutated Nck SH2/SH3 adaptor respecifies mesodermal cell fate in Xenopus laevis development.
score: 5.7761151, Proceedings of the National Academy of Sciences of the United States of America, 1997, Tanaka, M; Lu, W; Gupta, R; Mayer, B J

Current world literature
score: 5.771695, Current Opinion in Biotechnology, 1997,

Vascular endothelial growth factor and angiogenesis.
score: 5.7681823, Pharmacological reviews, 2004, Hoeben, Ann et. al.

Face off — the interplay between activating and inhibitory immune receptors
score: 5.747515, Current Opinion in Immunology, 2001, Lanier, Lewis L

Sprouty2 binds Grb2 at two different proline-rich regions, and the mechanism of ERK inhibition is independent of this interaction
score: 5.7430878, Cellular Signalling, 2007, Martínez, Natalia et. al.

Regulation of nuclear factor kappaB activation by G-protein-coupled receptors.
score: 5.729372, Journal of leukocyte biology, 2001, Ye, R D

Tyrosine kinase activation in the decision between growth, differentiation, and death responses initiated from the B cell antigen receptor
score: 5.7190033, Advances in Immunology, 2000, Hsueh, Robert C.; Scheuermann, Richard H.

Inhibition of β2 Integrin Receptor and Syk Kinase Signaling in Monocytes by the Src Family Kinase Fgr
score: 5.7140329, Immunity, 2001, Vines, Charlotte M et. al.

Changes in actin dynamics at the T-cell/APC interface: implications for T-cell anergy?
score: 5.7040108, Immunological reviews, 2002, Sechi, Antonio S et. al.

p38alpha isoform Mxi2 binds to extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase and regulates its nuclear activity by sustaining its phosphorylation levels.
score: 5.703022, Molecular and cellular biology, 2003, Sanz-Moreno, Victoria; Casar, Berta; Crespo, Piero

Ethanol inhibits L1 cell adhesion molecule activation of mitogen-activated protein kinases.
score: 5.702097, Journal of neurochemistry, 2006, Tang, Ningfeng et. al.

Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation.
score: 5.7009095, The EMBO journal, 1999, De Sepulveda, P et. al.

Inhibitory Receptor Signaling via Tyrosine Phosphorylation of the Adaptor Crk
score: 5.6947776, Immunity, 2008, Peterson, Mary E.; Long, Eric O.

B cell receptor-mediated Syk-independent activation of phosphatidylinositol 3-kinase, Ras, and mitogen-activated protein kinase pathways.
score: 5.6940543, Journal of immunology (Baltimore, Md. : 1950), 2003, Yokozeki, Takeaki et. al.

Specialised adaptors in immune cells
score: 5.6928114, Current Opinion in Cell Biology, 2004, Veillette, André

Type I Inteferon Gene Induction by the Interferon Regulatory Factor Family of Transcription Factors
score: 5.6925606, Immunity, 2006, Honda, Kenya; Takaoka, Akinori; Taniguchi, Tadatsugu

Akt-Dependent Cytokine Production in Mast Cells
score: 5.6897933, The Journal of Experimental Medicine, 2000, Kitaura, Jiro et. al.

Gelatinase-mediated migration and invasion of cancer cells
score: 5.6889447, BBA - Reviews on Cancer, 2005, Björklund, Mikael; Koivunen, Erkki

Visualization of SHP-1-target interaction.
score: 5.6871939, Journal of cell science, 2004, Biskup, Christoph et. al.

Analysis of the L1-Deficient Mouse Phenotype Reveals Cross-Talk between Sema3A and L1 Signaling Pathways in Axonal Guidance
score: 5.684905, Neuron, 2000, Castellani, Valérie et. al.

Notch Signaling: The Core Pathway and Its Posttranslational Regulation
score: 5.6825718, Developmental Cell, 2009, Fortini, Mark E.

Molecular and Cellular Mechanisms of T Lymphocyte Apoptosis
score: 5.6817477, Advances in Immunology, 1998, Penninger, Josef M.; Kroemer, Guido

Molecular and Cellular Mechanisms of T Lymphocyte Apoptosis
score: 5.6817477, Advances in Immunology, 1998, Penninger, Josef M.; Kroemer, Guido

SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling.
score: 5.6792322, Molecular and cellular biology, 2000, Blake, R A et. al.

Proteinase-activated receptors.
score: 5.6767817, Pharmacological reviews, 2001, Macfarlane, S R et. al.

A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.
score: 5.673931, Proceedings of the National Academy of Sciences of the United States of America, 1996, O'Bryan, J P; Songyang, Z; Cantley, L; Der, C J; Pawson, T

Csk-homologous kinase interacts with SHPS-1 and enhances neurite outgrowth of PC12 cells.
score: 5.6705045, Journal of neurochemistry, 2008, Mitsuhashi, Hiroaki et. al.

A human nuclear shuttling protein that interacts with human immunodeficiency virus type 1 matrix is packaged into virions.
score: 5.6684264, Journal of virology, 2000, Gupta, K; Ott, D; Hope, T J; Siliciano, R F; Boeke, J D

Transcytosis of NgCAM in epithelial cells reflects differential signal recognition on the endocytic and secretory pathways
score: 5.6639362, The Journal of Cell Biology, 2005, Anderson, Eric et. al.

The Cell Biology of the Prohormone Convertases PCI and PC2
score: 5.6579635, Progress in Nucleic Acid Research and Molecular Biology, 1999, Muller, L.; Lindberg, I.

The Cell Biology of the Prohormone Convertases PCI and PC2
score: 5.6579635, Progress in Nucleic Acid Research and Molecular Biology, 1999, Muller, L.; Lindberg, I.

The Cell Biology of the Prohormone Convertases PCI and PC2
score: 5.6579635, Progress in Nucleic Acid Research and Molecular Biology, 1999, Muller, L.; Lindberg, I.

Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse.
score: 5.6575214, Molecular and cellular biology, 2007, Giurisato, Emanuele et. al.

c-Cbl regulates migration of v-Abl-transformed NIH 3T3 fibroblasts via Rac1
score: 5.6520833, Experimental Cell Research, 2005, Teckchandani, Anjali M. et. al.

Pharmaceutical applications
score: 5.6501032, Current Opinion in Biotechnology, 1993,

Mammalian gene studies
score: 5.6457052, Current Opinion in Biotechnology, 1994,

Current Views in Intracellular Transport: Insights from Studies in Immunology
score: 5.6423505, Advances in Immunology, 1998, Hsu, Victor W.; Peters, Peter J.

A novel complex, p40/42, is constitutively associated with the B cell antigen receptor and phosphorylated upon receptor stimulation.
score: 5.6389862, Journal of immunology (Baltimore, Md. : 1950), 1996, Lee, Y J; Luisiri, P; Clark, M R

In vitro nuclear interactome of the HIV-1 Tat protein
score: 5.6347334, Retrovirology, 2009, Gautier, Virginie W et. al.

Vav3 Modulates B Cell Receptor Responses by Regulating Phosphoinositide 3-Kinase Activation
score: 5.6249422, The Journal of Experimental Medicine, 2002, Inabe, Kazunori et. al.

IRS-1 and IRS-2 are recruited by TrkA receptor and oncogenic TRK-T1.
score: 5.6246548, Journal of cellular physiology, 2001, Miranda, C et. al.

Recruitment of SHP-1 protein tyrosine phosphatase and signalling by a chimeric T-cell receptor-killer inhibitory receptor.
score: 5.6243463, Scandinavian journal of immunology, 2000, Christensen, M D; Geisler, C

A role for GRIP domain proteins and/or their ligands in structure and function of the trans Golgi network.
score: 5.6231461, Journal of cell science, 2003, Yoshino, Atsuko et. al.

Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells.
score: 5.6145453, Journal of leukocyte biology, 1999, Zhang, S; Mantel, C; Broxmeyer, H E

EPAC proteins transduce diverse cellular actions of cAMP.
score: 5.6128416, British journal of pharmacology, 2009, Borland, Gillian; Smith, Brian O; Yarwood, Stephen J

Ubiquitin and endocytic internalization in yeast and animal cells
score: 5.6086455, BBA - Molecular Cell Research, 2004, Dupré, S.; Urban-Grimal, D.; Haguenauer-Tsapis, R.

Receptor-stimulated oxidation of SHP-2 promotes T-cell adhesion through SLP-76-ADAP.
score: 5.5964703, The EMBO journal, 2005, Kwon, Jaeyul et. al.

TLR3: Interferon induction by double-stranded RNA including poly(I:C)
score: 5.5945278, Advanced Drug Delivery Reviews, 2008, Matsumoto, Misako; Seya, Tsukasa

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck
score: 5.5858287, Current Biology, 1997, Lu, Wange; Katz, Steve; Gupta, Ruchika; Mayer, Bruce J.

A Cytoplasmic ATM-TRAF6-cIAP1 Module Links Nuclear DNA Damage Signaling to Ubiquitin-Mediated NF-κB Activation
score: 5.5851066, Molecular Cell, 2010, Hinz, Michael et. al.

A Cytoplasmic ATM-TRAF6-cIAP1 Module Links Nuclear DNA Damage Signaling to Ubiquitin-Mediated NF-κB Activation
score: 5.5851066, Molecular Cell, 2010, Hinz, Michael et. al.

The complexity of targeting EGFR signalling in cancer: From expression to turnover
score: 5.5848891, BBA - Reviews on Cancer, 2006, Sebastian, Sinto et. al.

ERK1/2 MAP kinases: Structure, function, and regulation
score: 5.5812491, Pharmacological Research, 2012, Roskoski, Robert

ERK1/2 MAP kinases: Structure, function, and regulation
score: 5.5812491, Pharmacological Research, 2012, Roskoski, Robert

ERK1/2 MAP kinases: Structure, function, and regulation
score: 5.5812491, Pharmacological Research, 2012, Roskoski, Robert

Signal Transduction Elements of the B Cell Antigen Receptor and their Role in Immunodeficiencies
score: 5.5809268, Immunobiology, 2000, Wienands, Jürgen

Caspase-dependent cleavage of the hematopoietic specific adaptor protein Gads alters signalling from the T cell receptor.
score: 5.5789334, Oncogene, 2001, Berry, D M; Benn, S J; Cheng, A M; McGlade, C J

The transforming potential of the c-erbB-2 protein is regulated by its autophosphorylation at the carboxyl-terminal domain.
score: 5.5754086, Molecular and cellular biology, 1991, Akiyama, T et. al.

The classification of seven transmembrane receptors in recombinant expression systems.
score: 5.5743568, Pharmacological reviews, 1996, Kenakin, T

Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage.
score: 5.5676918, Molecular and cellular biology, 1999, Huang, Y et. al.

Modular Architecture and Novel Protein–Protein Interactions Regulating the RGS-Containing Rho Guanine Nucleotide Exchange Factors
score: 5.5626398, Methods in Enzymology, 2004, Vázquez-Prado, José; Basile, John; Gutkind, J.Silvio

Deubiquitinases in the regulation of NF-κB signaling.
score: 5.5624749, Cell research, 2011, Harhaj, Edward W; Dixit, Vishva M

Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase.
score: 5.5604386, Molecular and cellular biology, 1999, Filippa, N et. al.

Phosphotyrosine-binding domains in signal transduction.
score: 5.5581801, Nature reviews. Molecular cell biology, 2002, Yaffe, Michael B

Oncogenes and cell proliferation
score: 5.5568344, Current Opinion in Genetics & Development, 1995,

Human herpesvirus 6 open reading frame U83 encodes a functional chemokine.
score: 5.5553224, Journal of virology, 1999, Zou, P et. al.

Syk- and Lyn-dependent phosphorylation of Syk on multiple tyrosines following B cell activation includes a site that negatively regulates signaling.
score: 5.5496172, Journal of immunology (Baltimore, Md. : 1950), 1998, Keshvara, L M et. al.

c-Cbl-mediated regulation of LAT-nucleated signaling complexes.
score: 5.5456196, Molecular and cellular biology, 2007, Balagopalan, Lakshmi et. al.

mRNA degradation machines in eukaryotic cells
score: 5.5435803, Biochimie, 2002, Tourrière, Hélène; Chebli, Karim; Tazi, Jamal

A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains.
score: 5.5421338, Molecular and cellular biology, 1992, Partanen, J et. al.

The association between glycosylphosphatidylinositol-anchored proteins and heterotrimeric G protein alpha subunits in lymphocytes.
score: 5.5405922, Proceedings of the National Academy of Sciences of the United States of America, 1996, Solomon, K R; Rudd, C E; Finberg, R W

Postgenomic global analysis of translational control induced by oncogenic signaling.
score: 5.5144755, Oncogene, 2004, Rajasekhar, Vinagolu K; Holland, Eric C

Pattern formation and developmental mechanism
score: 5.5128599, Current Opinion in Genetics & Development, 1995,

MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death.
score: 5.5123304, Proceedings of the National Academy of Sciences of the United States of America, 1997, Han, D K et. al.

DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur
score: 5.5030976, The Journal of Cell Biology, 2007, Nichols, James T. et. al.

Sequence-non-specific effects of RNA interference triggers and microRNA regulators
score: 5.5018391, Nucleic Acids Research, 2009, Olejniczak, Marta et. al.

Folding and binding
score: 5.4989591, Current Opinion in Structural Biology, 1995,

Insights into seven and single transmembrane-spanning domain receptors and their signaling pathways in human natural killer cells.
score: 5.4979894, Pharmacological reviews, 2005, Maghazachi, Azzam A

Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells.
score: 5.4964889, Journal of immunology (Baltimore, Md. : 1950), 2000, Hehner, S P et. al.

Oncoprotein Networks
score: 5.4848943, Cell, 1997, Hunter, Tony

The gamma and epsilon subunits of the CD3 complex inhibit pre-Golgi degradation of newly synthesized T cell antigen receptors
score: 5.4827198, The Journal of Cell Biology, 1990,

Activation of the MAP Kinase Pathway by FGF-1 Correlates with Cell Proliferation Induction While Activation of the Src Pathway Correlates with Migration
score: 5.4812724, The Journal of Cell Biology, 1998, LaVallee, Theresa M. et. al.

NF-kappaB and the immune response.
score: 5.4737658, Oncogene, 2006, Hayden, M S; West, A P; Ghosh, S

Conformational Plasticity and Navigation of Signaling Proteins in Antigen-Activated B Lymphocytes
score: 5.4734524, Advances in Immunology, 2008, Engels, Niklas; Engelke, Michael; Wienands, Jürgen

Conformational Plasticity and Navigation of Signaling Proteins in Antigen-Activated B Lymphocytes
score: 5.4734524, Advances in Immunology, 2008, Engels, Niklas; Engelke, Michael; Wienands, Jürgen

Insulin Activation of Mitogen-Activated Protein (MAP) Kinase and Akt Is Phosphatidylinositol 3-Kinase-Dependent in Rat Adipocytes
score: 5.4731152, Biochemical and Biophysical Research Communications, 2000, Liu, Hongzhi et. al.

The human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation technique.
score: 5.471753, Nucleic acids research, 2011, Totaro, Antonio et. al.

Rapamycin-sensitive phosphorylation of PKC on a carboxy-terminal site by an atypical PKC complex
score: 5.4654011, Current Biology, 1999, Ziegler, W.H. et. al.

Dual effects of Sprouty1 on TCR signaling depending on the differentiation state of the T cell.
score: 5.4524151, Journal of immunology (Baltimore, Md. : 1950), 2006, Choi, Heonsik et. al.

Negative regulation of lymphocyte activation by the adaptor protein LAX.
score: 5.4523913, Journal of immunology (Baltimore, Md. : 1950), 2005, Zhu, Minghua et. al.

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation.
score: 5.4481712, Molecular and cellular biology, 1994, Sieh, M; Batzer, A; Schlessinger, J; Weiss, A

Protein Tyrosine Phosphatases and the Control of Cellular Signaling Responses
score: 5.4396398, Advances in Pharmacology, 1996, Tonks, N.K.

Folding and binding
score: 5.4375488, Current Opinion in Structural Biology, 1996,

Raf kinases in cancer-roles and therapeutic opportunities.
score: 5.4358176, Oncogene, 2011, Maurer, G; Tarkowski, B; Baccarini, M

PAK Kinases Are Directly Coupled to the PIX Family of Nucleotide Exchange Factors
score: 5.4261074, Molecular Cell, 1998, Manser, Edward et. al.

A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy.
score: 5.4246017, Nature medicine, 2009, Lorenz, Kristina et. al.

Cell Adhesion Molecules during Inner Ear and Hair Cell Development, Including Notch and Its Ligands
score: 5.4242169, Current Topics in Developmental Biology, 2003, Kelley, Matthew W

Cell Adhesion Molecules during Inner Ear and Hair Cell Development, Including Notch and Its Ligands
score: 5.4242169, Current Topics in Developmental Biology, 2003, Kelley, Matthew W

The axonal recognition molecule F11 is a multifunctional protein: Specific domains mediate interactions with Ng-CAM and restrictin
score: 5.4171478, Neuron, 1993, Brm̈mendorf, Thomas et. al.

Contents
score: 5.4159427, Current Opinion in Genetics & Development, 1997,

Signal processing by its coil zipper domain activates IKK gamma.
score: 5.4155563, Proceedings of the National Academy of Sciences of the United States of America, 2008, Bloor, Stuart et. al.

Oxidative stress and gene regulation
score: 5.4147104, Free Radical Biology and Medicine, 2000, Allen, R.G; Tresini, Maria

Bibliography of the current world literature
score: 5.4126953, Current Opinion in Immunology, 1995,

The roles of receptor and ligand endocytosis in regulating Notch signaling.
score: 5.4126163, Development (Cambridge, England), 2005, Le Borgne, Roland; Bardin, Allison; Schweisguth, François

Signaling network of dendritic cells in response to pathogens: a community-input supported knowledgebase
score: 5.4052216, BMC Systems Biology, 2010, Patil, Sonali et. al.

Plasmacytoid dendritic cell–specific receptor ILT7–FcɛRIγ inhibits Toll-like receptor–induced interferon production
score: 5.4030821, The Journal of Experimental Medicine, 2006, Cao, Wei et. al.

IQGAP1-Dependent Signaling Pathway Regulates Endothelial Cell Proliferation and Angiogenesis
score: 5.4011433, PLoS ONE, 2008, Meyer, Rosana D.; Sacks, David B.; Rahimi, Nader

Molecular separation of two signaling pathways for the receptor, Notch
score: 5.3995651, Developmental Biology, 2008, Le Gall, Maude; De Mattei, Cordell; Giniger, Edward

Cdk2 and Pin1 negatively regulate the transcriptional corepressor SMRT
score: 5.3987543, The Journal of Cell Biology, 2008, Stanya, Kristopher J. et. al.

Centrosomal targeting of Syk kinase is controlled by its catalytic activity and depends on microtubules and the dynein motor.
score: 5.398094, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Fargier, Guillaume et. al.

Identification of functional domains in the hepatocyte growth factor and its receptor by molecular engineering
score: 5.3958413, Journal of Biotechnology, 1994, Bardelli, A.; Ponzetto, C.; Comoglio, P.M.

The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins.
score: 5.394465, Proceedings of the National Academy of Sciences of the United States of America, 2002, Egan, James E et. al.

Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases.
score: 5.3928611, Journal of cell science, 2009, Tifft, Kathryn E; Bradbury, Katherine A; Wilson, Katherine L

Isolation and characterization of the Pin1/Ess1p homologue in Schizosaccharomyces pombe.
score: 5.3906125, Journal of cell science, 2001, Huang, H K et. al.

A history of poly A sequences: from formation to factors to function
score: 5.386786, Progress in Nucleic Acid Research and Molecular Biology, 2002, Edmonds, Mary

A history of poly A sequences: from formation to factors to function
score: 5.386786, Progress in Nucleic Acid Research and Molecular Biology, 2002, Edmonds, Mary

Syk, c-Src, the αvβ3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption
score: 5.3865455, The Journal of Cell Biology, 2007, Zou, Wei et. al.

Role of NK and NKT cells in the immunopathogenesis of HCV-induced hepatitis.
score: 5.3844432, Journal of leukocyte biology, 2004, Ahmad, Ali; Alvarez, Fernando

The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands
score: 5.3763619, The Journal of Cell Biology, 2005, Ladi, Ena et. al.

A Ras Signaling Complex Controls the RasC-TORC2 Pathway and Directed Cell Migration
score: 5.3734512, Developmental Cell, 2010, Charest, Pascale G. et. al.

Vav GEFs are required for β 2 integrin-dependent functions of neutrophils
score: 5.3696347, The Journal of Cell Biology, 2004, Gakidis, M. Angelica Martinez et. al.

Yersinia pseudotuberculosis virulence determinants invasin, YopE, and YopT modulate RhoG activity and localization.
score: 5.3681924, Infection and immunity, 2009, Mohammadi, Sina; Isberg, Ralph R

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death.
score: 5.3653831, Proceedings of the National Academy of Sciences of the United States of America, 2001, Suzuki, Y; Nakabayashi, Y; Takahashi, R

Genetic dissection of antigen receptor induced-NF-κB activation
score: 5.3639647, Molecular Immunology, 2004, Li, Zhi-Wei; Rickert, Robert C; Karin, Michael

The Shb signalling scaffold binds to and regulates constitutive signals from the Epstein-Barr virus LMP2A membrane protein.
score: 5.3599092, Oncogene, 2007, Matskova, L V et. al.

RhoA GTPase activation by TLR2 and TLR3 ligands: connecting via Src to NF-kappa B.
score: 5.3550504, Journal of immunology (Baltimore, Md. : 1950), 2009, Manukyan, Maria et. al.

Regulation of cardiac myocyte cell death
score: 5.3531979, Pharmacology and Therapeutics, 2003, Clerk, Angela et. al.

Structural basis of G protein-coupled receptor function
score: 5.3479059, Molecular and Cellular Endocrinology, 1999, Schöneberg, Torsten; Schultz, Günter; Gudermann, Thomas

Recruitment of the extracellular signal-regulated kinase/ribosomal S6 kinase signaling pathway to the NFATc4 transcription activation complex.
score: 5.3421943, Molecular and cellular biology, 2005, Yang, Teddy T C et. al.

Targeting phosphoinositide 3-kinase—Moving towards therapy
score: 5.3382721, BBA - Proteins and Proteomics, 2008, Marone, Romina et. al.

Malt1 and cIAP2–Malt1 as effectors of NF-κB activation: Kissing cousins or distant relatives?
score: 5.3303533, Cellular Signalling, 2010, Kingeter, Lara M.; Schaefer, Brian C.

Critical Role for Asparagine Endopeptidase in Endocytic Toll-like Receptor Signaling in Dendritic Cells
score: 5.3245017, Immunity, 2009, Sepulveda, Fernando E. et. al.

Notch signalling: a simple pathway becomes complex.
score: 5.3234512, Nature reviews. Molecular cell biology, 2006, Bray, Sarah J

TLR4/MyD88/PI3K interactions regulate TLR4 signaling.
score: 5.3219977, Journal of leukocyte biology, 2009, Laird, Michelle H W et. al.

Membranes and sorting
score: 5.3199535, Current Opinion in Cell Biology, 1995,

Antigen recognition
score: 5.3163778, Current Opinion in Immunology, 1996,

Kinetics and peptide dependency of the binding of the inhibitory NK receptor CD94/NKG2-A and the activating receptor CD94/NKG2-C to HLA-E.
score: 5.3163231, The EMBO journal, 1999, Valés-Gómez, M et. al.

TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL CONTROL OF GENE EXPRESSION IN INFLAMMATION
score: 5.3140587, Cytokine, 2002, Kracht, Michael; Saklatvala, Jeremy

The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions.
score: 5.3140255, Journal of immunology (Baltimore, Md. : 1950), 2003, Kim, Chaekyun et. al.

Studies of a germinal centre B-cell expressed gene, GCET2, suggest its role as a membrane associated adapter protein.
score: 5.3075897, British journal of haematology, 2007, Pan, Zenggang et. al.

Efficient and specific rescue of human immunodeficiency virus type 1 budding defects by a Nedd4-like ubiquitin ligase.
score: 5.2985955, Journal of virology, 2008, Usami, Yoshiko et. al.

Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells.
score: 5.2974548, The EMBO journal, 1997, Holland, S J et. al.

The Transmembrane Protein Off-Track Associates with Plexins and Functions Downstream of Semaphorin Signaling during Axon Guidance
score: 5.295936, Neuron, 2001, Winberg, Margaret L. et. al.

Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor.
score: 5.2925676, Cancer research, 2005, Timpson, Paul et. al.

CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76.
score: 5.2878826, Molecular and cellular biology, 2006, Hassan, Namir J et. al.

The interplay between viruses and innate immune signaling: Recent insights and therapeutic opportunities
score: 5.2871177, Biochemical Pharmacology, 2008, Unterholzner, Leonie; Bowie, Andrew G.

Killer Cell Inhibitory Receptor Recognition of Human Leukocyte Antigen (HLA) Class I Blocks Formation of a pp36/PLC-γ Signaling Complex in Human Natural Killer (NK) Cells
score: 5.2846511, The Journal of Experimental Medicine, 1996, Valiante, Nicholas M. et. al.

Immunobiology of toll-like receptors in allergic disease
score: 5.2841785, Immunobiology, 2007, Bauer, Stefan; Hangel, Doris; Yu, Philipp

Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins.
score: 5.2824708, The EMBO journal, 2004, Hettema, Ewald H; Valdez-Taubas, Javier; Pelham, Hugh R B

Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis
score: 5.281426, Biochemical and Biophysical Research Communications, 2006, Tsukamoto, Satoshi et. al.

UV induces tyrosine kinase-independent internalisation and endosome arrest of the EGF receptor.
score: 5.2814137, Journal of cell science, 2002, Oksvold, Morten P et. al.

The Role of SH2 Domain-containing Leukocyte Phosphoprotein of 76 kDa in the Regulation of Immune Cell Development and Function
score: 5.2771705, Immune Network : Official Journal of the Korean Society for Immunology and Biological Response Modifiers, 2009, Koretzky, Gary A.

The Selectivity of Receptor Tyrosine Kinase Signaling Is Controlled by a Secondary SH2 Domain Binding Site
score: 5.2765455, Cell, 2009, Bae, Jae Hyun et. al.

The Inhibitory Receptor LIR-1 Uses a Common Binding Interaction to Recognize Class I MHC Molecules and the Viral Homolog UL18
score: 5.2703012, Immunity, 1999, Chapman, Tara L; Heikema, Astrid P; Bjorkman, Pamela J

Suppressor and oncogenic roles of transforming growth factor-β and its signaling pathways in tumorigenesis
score: 5.2685453, Advances in Cancer Research, 2001, Piek, Ester; Roberts, Anita B.

Gapex-5, a Rab31 Guanine Nucleotide Exchange Factor that Regulates Glut4 Trafficking in Adipocytes
score: 5.2632025, Cell Metabolism, 2007, Lodhi, Irfan J. et. al.

Nischarin, a Novel Protein That Interacts with the Integrin α5 Subunit and Inhibits Cell Migration
score: 5.2629838, The Journal of Cell Biology, 2000, Alahari, Suresh K.; Lee, Jung Weon; Juliano, Rudy L.

Cell responses to FGFR3 signalling: growth, differentiation and apoptosis
score: 5.2570927, Experimental Cell Research, 2005, L'Hôte, Corine G.M.; Knowles, Margaret A.

Differential association of phosphatidylinositol 3-kinase with insulin receptor substrate (IRS)-1 and IRS-2 in human thymocytes in response to IL-7.
score: 5.2507453, Journal of immunology (Baltimore, Md. : 1950), 1997, Sharfe, N; Roifman, C M

Dynamics of Endosomal Sorting
score: 5.2500055, International Review of Cytology, 2003, Bishop, Naomi E.

Dynamics of Endosomal Sorting
score: 5.2500055, International Review of Cytology, 2003, Bishop, Naomi E.

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells
score: 5.2486658, The Journal of Experimental Medicine, 1995,

Enhancement of fcgamma receptor-mediated phagocytosis by transforming mutants of Cbl.
score: 5.2382719, Journal of immunology (Baltimore, Md. : 1950), 1999, Sato, N; Kim, M K; Schreiber, A D

NK cell activity during human cytomegalovirus infection is dominated by US2-11-mediated HLA class I down-regulation.
score: 5.2364486, Journal of immunology (Baltimore, Md. : 1950), 2002, Falk, Christine S et. al.

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck
score: 5.2273019, Current Biology, 1997, Lu, Wange; Katz, Steve; Gupta, Ruchika; Mayer, Bruce J.

An analysis of vertebrate mRNA sequences: intimations of translational control
score: 5.21845, The Journal of Cell Biology, 1991,

Differential regulation of p72 syk expression in naive and proliferating CD4 −CD8 + T cells
score: 5.2138004, Molecular Immunology, 1996, Orchansky, Patricia L. et. al.

Growth factor signaling by receptor tyrosine kinases
score: 5.2090391, Neuron, 1992, Schlessinger, J.; Ullrich, A.

Regulation of VEGF signaling by membrane traffic
score: 5.2027945, Cellular Signalling, 2012, Horowitz, Arie; Seerapu, Himabindu Reddy

Genetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases.
score: 5.2011069, Molecular and cellular biology, 1998, Wong, J; Straus, D; Chan, A C

The Focal Adhesion Targeting Domain of Focal Adhesion Kinase Contains a Hinge Region that Modulates Tyrosine 926 Phosphorylation
score: 5.200628, Structure, 2004, Prutzman, Kirk C et. al.

Mechanisms of ErbB receptor negative regulation and relevance in cancer
score: 5.1991802, Experimental Cell Research, 2009, Fry, William H.D. et. al.

Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage
score: 5.1957467, Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2006, Bahassi, El Mustapha et. al.

Activation of Vav by the gammaherpesvirus M2 protein contributes to the establishment of viral latency in B lymphocytes.
score: 5.1944999, Journal of virology, 2006, Rodrigues, Lénia et. al.

NK cells and their receptors
score: 5.1904014, Reproductive BioMedicine Online, 2008, Yokoyama, Wayne M; Riley, Joan K

CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation
score: 5.1875322, The Journal of Experimental Medicine, 1996,

SH2B1beta adaptor is a key enhancer of RET tyrosine kinase signaling.
score: 5.1778308, Oncogene, 2007, Donatello, S et. al.

Flesh and blood: The story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies
score: 5.1680184, Cancer Letters, 2007, Katzav, Shulamit

Functional differences between Stat3alpha and Stat3beta.
score: 5.1638222, Molecular and cellular biology, 1997, Schaefer, T S; Sanders, L K; Park, O K; Nathans, D

Interactions Between NK Cells and B Lymphocytes
score: 5.1596643, Advances in Immunology, 2004, Yuan, Dorothy

Structural and functional associations of apical junctions with cytoskeleton
score: 5.1553487, BBA - Biomembranes, 2008, Miyoshi, Jun; Takai, Yoshimi

CD94/NKG2A inhibits NK cell activation by disrupting the actin network at the immunological synapse.
score: 5.1498305, Journal of immunology (Baltimore, Md. : 1950), 2006, Masilamani, Madhan et. al.

Protein binding and signaling properties of RIN1 suggest a unique effector function.
score: 5.1481422, Proceedings of the National Academy of Sciences of the United States of America, 1997, Han, L et. al.

Proteins of the Myc Network: Essential Regulators of Cell Growth and Differentiation
score: 5.142846, Advances in Cancer Research, 1996, Henriksson, Marie; Lüscher, Bernhard

Approaching the Asymptote: 20 Years Later
score: 5.1419643, Immunity, 2009, Medzhitov, Ruslan

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling
score: 5.1411757, Cell, 1992, Lowenstein, E.J. et. al.

Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome.
score: 5.1396281, Nature structural & molecular biology, 2008, Mathew, Rebecca et. al.

Matrikines and the lungs
score: 5.1395485, Pharmacology and Therapeutics, 2012, Burgess, Janette K.; Weckmann, Markus

Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II.
score: 5.1388457, Proceedings of the National Academy of Sciences of the United States of America, 1992, Dvir, A; Peterson, S R; Knuth, M W; Lu, H; Dynan, W S

N-linked carbohydrate on human leukocyte antigen-C and recognition by natural killer cell inhibitory receptors
score: 5.1378076, Human Immunology, 2000, Baba, Eishi et. al.

p53/58 Binds COPI and Is Required for Selective Transport through the Early Secretory Pathway
score: 5.1371016, The Journal of Cell Biology, 1997, Tisdale, Ellen J. et. al.

The immunoreceptor adapter protein DAP12 suppresses B lymphocyte–driven adaptive immune responses
score: 5.1354662, The Journal of Experimental Medicine, 2011, Nakano-Yokomizo, Takako et. al.

HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels.
score: 5.1311109, Journal of cell science, 2003, Masson, Norma; Ratcliffe, Peter J

Tumor necrosis factor signaling.
score: 5.1302998, Cell death and differentiation, 2003, Wajant, H; Pfizenmaier, K; Scheurich, P

Emerging roles for ubiquitin and protein degradation in neuronal function.
score: 5.1272622, Pharmacological reviews, 2007, Yi, Jason J; Ehlers, Michael D

Defective posttranslational processing activates the tyrosine kinase encoded by the MET proto-oncogene (hepatocyte growth factor receptor).
score: 5.1272187, Molecular and cellular biology, 1991, Mondino, A; Giordano, S; Comoglio, P M

Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells.
score: 5.1267781, Molecular and cellular biology, 2003, Kettner, Alexander et. al.

Recent progress in insulin signal transduction
score: 5.125445, Journal of Pharmacological and Toxicological Methods, 1998, Hei, Yong-Jiang

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action.
score: 5.1236474, Proceedings of the National Academy of Sciences of the United States of America, 1997, Eldar-Finkelman, H; Krebs, E G

Insulin-like Growth Factor Binding Proteins
score: 5.1224973, Vitamins and Hormones, 1993, Rechler, Matthew M.

Inhibitory Role of α6β4-Associated Erbb-2 and Phosphoinositide 3-Kinase in Keratinocyte Haptotactic Migration Dependent on α3β1 Integrin
score: 5.1222973, The Journal of Cell Biology, 2001, Hintermann, Edith et. al.

STATs as critical mediators of signal transduction and transcription: lessons learned from STAT5
score: 5.1218917, Cytokine and Growth Factor Reviews, 2004, Paukku, Kirsi; Silvennoinen, Olli

Phosphoinositide 3-kinase signalling pathways.
score: 5.1190615, Journal of cell science, 2001, Cantrell, D A

Pinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1
score: 5.1188581, FEBS Letters, 2006, Koo, Diana H.H. et. al.

Ras effector pathways modulate scatter factor-stimulated NF-kappaB signaling and protection against DNA damage.
score: 5.1178236, Oncogene, 2007, Fan, S; Meng, Q; Laterra, J J; Rosen, E M

Targeted Cleavage of Signaling Proteins by Caspase 3 Inhibits T Cell Receptor Signaling in Anergic T Cells
score: 5.1146858, Immunity, 2008, Puga, Irene; Rao, Anjana; Macian, Fernando

Gbeta gamma -independent constitutive association of Galpha s with SHP-1 and angiotensin II receptor AT2 is essential in AT2-mediated ITIM-independent activation of SHP-1.
score: 5.1102468, Proceedings of the National Academy of Sciences of the United States of America, 2002, Feng, Ying-Hong; Sun, Yan; Douglas, Janice G

Negative Regulation of Cytokine and TLR Signalings by SOCS and Others
score: 5.1094017, Advances in Immunology, 2005, Naka, Tetsuji et. al.

Pattern formation and developmental mechanisms
score: 5.1088752, Current Opinion in Genetics & Development, 1996,

Intracellular signaling is changed after clustering of the neural cell adhesion molecules axonin-1 and NgCAM during neurite fasciculation
score: 5.1084582, The Journal of Cell Biology, 1996,

Mechanisms of FGFR-mediated carcinogenesis
score: 5.1076284, BBA - Molecular Cell Research, 2012, Ahmad, Imran; Iwata, Tomoko; Leung, Hing Y.

Mechanisms of FGFR-mediated carcinogenesis
score: 5.1076284, BBA - Molecular Cell Research, 2012, Ahmad, Imran; Iwata, Tomoko; Leung, Hing Y.

Rapamycin-sensitive phosphorylation of PKC on a carboxy-terminal site by an atypical PKC complex
score: 5.1068744, Current Biology, 1999, Ziegler, W.H. et. al.

Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function
score: 5.1033474, Molecular Aspects of Medicine, 2002, Jackson, Malcolm J. et. al.

Intracellular Protein Traffic in Lymphocytes
score: 5.1032461, Immunity, 1999, Roche, Paul A

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
score: 5.1024562, Cell, 1994, Ponzetto, Carola et. al.

The antigen presentation pathway in medullary thymic epithelial cells, but not that in cortical thymic epithelial cells, conforms to the endocytic pathway.
score: 5.0995704, European journal of immunology, 1998, Kasai, M; Kominami, E; Mizuochi, T

Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake
score: 5.0989972, Cell Metabolism, 2006, Gong, Yi et. al.

Bibliography of the current world literature
score: 5.0927735, Current Opinion in Neurobiology, 1992,

PI3K signaling controls cell fate at many points in B lymphocyte development and activation
score: 5.0918912, Seminars in Cell and Developmental Biology, 2004, Donahue, Amber C.; Fruman, David A.

ErbB2 and ErbB4 Cbl binding sites can functionally replace the ErbB1 Cbl binding site
score: 5.0886047, Cellular Signalling, 2009, Jansen, Suzanne M. et. al.

Primary human CD4+ T cells contain heterogeneous I kappa B kinase complexes: role in activation of the IL-2 promoter.
score: 5.0881361, Journal of immunology (Baltimore, Md. : 1950), 1999, Khoshnan, A et. al.

Proteins of the Myc Network: Essential Regulators of Cell Growth and Differentiation
score: 5.0879493, Advances in Cancer Research, 1996, Henriksson, Marie; Lüscher, Bernhard

Interplay between cell adhesion and growth factor receptors: from the plasma membrane to the endosomes
score: 5.0879308, Cell and Tissue Research, 2009, Ivaska, Johanna; Heino, Jyrki

Proteolytic signaling by TNFα: caspase activation and IκB degradation
score: 5.0870067, Cytokine, 2003, Hu, Xiaotang

The Adaptor SAP Controls NK Cell Activation by Regulating the Enzymes Vav-1 and SHIP-1 and by Enhancing Conjugates with Target Cells
score: 5.0804882, Immunity, 2012, Dong, Zhongjun et. al.

The Adaptor SAP Controls NK Cell Activation by Regulating the Enzymes Vav-1 and SHIP-1 and by Enhancing Conjugates with Target Cells
score: 5.0804882, Immunity, 2012, Dong, Zhongjun et. al.

Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
score: 5.0802569, Molecular Cell, 2009, Haas, Tobias L. et. al.

Insulin-like growth factor I receptor signaling in transformation by src oncogenes.
score: 5.0778996, Molecular and cellular biology, 1997, Valentinis, B; Morrione, A; Taylor, S J; Baserga, R

Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E
score: 5.0760795, Cell, 2010, Kim, Yumi et. al.

Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor.
score: 5.072562, Journal of immunology (Baltimore, Md. : 1950), 1996, Sutherland, C L et. al.

Deubiquitination of EGFR by Cezanne-1 contributes to cancer progression.
score: 5.0645585, Oncogene, 2012, Pareja, F et. al.

The regulatory particle of the Saccharomyces cerevisiae proteasome.
score: 5.0633431, Molecular and cellular biology, 1998, Glickman, M H; Rubin, D M; Fried, V A; Finley, D

Interactions of Bacterial Proteins with Host Eukaryotic Ubiquitin Pathways
score: 5.0617557, Frontiers in Microbiology, 2011, Perrett, Charlotte Averil; Lin, David Yin-Wei; Zhou, Daoguo

Stimulation of macrophage Fc gamma RIIIA activates the receptor-associated protein tyrosine kinase Syk and induces phosphorylation of multiple proteins including p95Vav and p62/GAP-associated protein.
score: 5.0569192, Journal of immunology (Baltimore, Md. : 1950), 1994, Darby, C; Geahlen, R L; Schreiber, A D

The transmembranal and cytoplasmic forms of protein tyrosine phosphatase epsilon physically associate with the adaptor molecule Grb2.
score: 5.0562331, Oncogene, 1999, Toledano-Katchalski, H; Elson, A

Codependent Functions of RSK2 and the Apoptosis-Promoting Factor TIA-1 in Stress Granule Assembly and Cell Survival
score: 5.0562247, Molecular Cell, 2008, Eisinger-Mathason, T.S. Karin et. al.

I-type lectins in the nervous system
score: 5.0551702, Progress in Neurobiology, 1999, Probstmeier, Rainer; Pesheva, Penka

Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1.
score: 5.0529605, The FEBS journal, 2007, Béraud-Dufour, Sophie et. al.

Regulation of protease-activated receptor signaling by post-translational modifications.
score: 5.0527535, IUBMB life, 2011, Grimsey, Neil; Soto, Antonio G; Trejo, JoAnn

Heparin-protein interactions.
score: 5.0524006, Angewandte Chemie (International ed. in English), 2002, Capila, Ishan; Linhardt, Robert J

Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia.
score: 5.0511082, Proceedings of the National Academy of Sciences of the United States of America, 2004, Cho, Jay Y et. al.

Integrin signalling and tyrosine phosphorylation: just the FAKs?
score: 5.0487124, Trends in Cell Biology, 1998, Schlaepfer, David D; Hunter, Tony

Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha.
score: 5.0460048, Journal of immunology (Baltimore, Md. : 1950), 2002, Siemasko, Karyn et. al.

Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.
score: 5.0408888, The EMBO journal, 1997, Migliaccio, E et. al.

Embryoglycan ectodomains regulate biological activity of FGF-2 to embryonic stem cells.
score: 5.036497, Journal of cell science, 1998, Dvorák, P et. al.

The Adaptor Protein Shc Couples a Class of Integrins to the Control of Cell Cycle Progression
score: 5.0354087, Cell, 1996, Wary, Kishore K et. al.

Regulation of angiogenesis via vascular endothelial growth factor receptors.
score: 5.0300582, Cancer research, 2000, Veikkola, T; Karkkainen, M; Claesson-Welsh, L; Alitalo, K

Crystal Structures and Inhibitors of Proteins Involved in IL‐2 Release and T Cell Signaling
score: 5.0293709, Vitamins and Hormones, 2006, Brown, Kieron; Cheetham, Graham M.T.

Crystal Structures and Inhibitors of Proteins Involved in IL‐2 Release and T Cell Signaling
score: 5.0293709, Vitamins and Hormones, 2006, Brown, Kieron; Cheetham, Graham M.T.

Negative feedback loop in T cell activation through IkappaB kinase-induced phosphorylation and degradation of Bcl10.
score: 5.0277316, Proceedings of the National Academy of Sciences of the United States of America, 2007, Lobry, Camille; Lopez, Tatiana; Israël, Alain; Weil, Robert

Posttranslational processing and differential glycosylation of Tractin, an Ig-superfamily member involved in regulation of axonal outgrowth
score: 5.0250635, Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular Enzymology, 2000, Jie, Chunfa et. al.

Association of the Src homology 2 domain-containing leukocyte phosphoprotein of 76 kD (SLP-76) with the p85 subunit of phosphoinositide 3-kinase
score: 5.0225969, FEBS Letters, 2004, Shim, Eun Kyung et. al.

Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I.
score: 5.0225384, Molecular and cellular biology, 2008, Bierhoff, Holger et. al.

Role of CBP in regulating HIF-1-mediated activation of transcription.
score: 5.0194563, Journal of cell science, 2005, Ruas, Jorge L; Poellinger, Lorenz; Pereira, Teresa

Heparan Sulfate Acts as a Bone Morphogenetic Protein Coreceptor by Facilitating Ligand-induced Receptor Hetero-oligomerization
score: 5.0176908, Molecular Biology of the Cell, 2010, Kuo, Wan-Jong; Digman, Michelle A.; Lander, Arthur D.

Cell biology of IL-7, a key lymphotrophin
score: 5.0174625, Cytokine and Growth Factor Reviews, 2005, Jiang, Qiong et. al.

The SAM domain of the RhoGAP DLC1 binds EF1A1 to regulate cell migration.
score: 5.0161172, Journal of cell science, 2009, Zhong, Dandan et. al.

Nedd8 on cullin: building an expressway to protein destruction.
score: 5.0159226, Oncogene, 2004, Pan, Zhen-Qiang et. al.

Drosophila MyD88 is an adapter in the Toll signaling pathway.
score: 5.015808, Proceedings of the National Academy of Sciences of the United States of America, 2001, Horng, T; Medzhitov, R

Structure and Content of the Entamoeba histolytica Genome
score: 5.0124152, Advances in Parasitology, 2007, Clark, C.G. et. al.

Structure and Content of theEntamoeba histolyticaGenome
score: 5.0124152, Advances in Parasitology, 2007, Clark, C.G. et. al.

Ubiquitin-proteasome-mediated local protein degradation and synaptic plasticity
score: 5.0104122, Progress in Neurobiology, 2004, Hegde, Ashok N.

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling.
score: 5.0059746, Proceedings of the National Academy of Sciences of the United States of America, 1996, Ishida, T K et. al.

TSAd interacts with Smad2 and Smad3
score: 5.004939, Biochemical and Biophysical Research Communications, 2006, Richard, K.C. et. al.

Crystal Structures of Two FGF-FGFR Complexes Reveal the Determinants of Ligand-Receptor Specificity
score: 5.001881, Cell, 2000, Plotnikov, Alexander N et. al.

Ubiquitin ligase adaptors: Regulators of ubiquitylation and endocytosis of plasma membrane proteins
score: 5.0001601, Experimental Cell Research, 2009, Léon, Sébastien; Haguenauer-Tsapis, Rosine

Signaling through CD5 activates a pathway involving phosphatidylinositol 3-kinase, Vav, and Rac1 in human mature T lymphocytes.
score: 4.9974007, Molecular and cellular biology, 1998, Gringhuis, S I; de Leij, L F; Coffer, P J; Vellenga, E

Molecular Cloning of the cDNA Encoding pp36, a Tyrosine-phosphorylated Adaptor Protein Selectively Expressed by T Cells and Natural Killer Cells
score: 4.9972779, The Journal of Experimental Medicine, 1998, Weber, John R. et. al.

Wiring the Vascular Circuitry: From Growth Factors to Guidance Cues
score: 4.9918662, Current Topics in Developmental Biology, 2004, Urness, Lisa D.; Li, Dean Y.

Oncogenic kinase signalling.
score: 4.9916663, Nature, 2001, Blume-Jensen, P; Hunter, T

Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.
score: 4.9898943, Molecular and cellular biology, 2009, Swiercz, Jakub M; Worzfeld, Thomas; Offermanns, Stefan

Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain.
score: 4.9870294, Journal of cell science, 2001, Citores, L et. al.

IRF7: activation, regulation, modification and function.
score: 4.9824221, Genes and immunity, 2011, Ning, S; Pagano, J S; Barber, G N

Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains.
score: 4.9819027, Proceedings of the National Academy of Sciences of the United States of America, 1994, Tanaka, N et. al.

Molecular Basis of Receptor/G-Protein-Coupling Selectivity
score: 4.9809427, Pharmacology and Therapeutics, 1998, Wess, Jürgen

Cbl
score: 4.9807835, Cellular Signalling, 1998, Liu, Yun-Cai; Altman, Amnon

Intracellular trafficking of Notch receptors and ligands
score: 4.9804746, Experimental Cell Research, 2009, Brou, Christel

Signal transduction by cell adhesion receptors
score: 4.9802869, BBA - Reviews on Cancer, 1995, Rosales, Carlos et. al.

T cell signaling:
score: 4.9756233, Human Immunology, 1999, Medema, Jan Paul; Borst, Jannie

The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinity.
score: 4.9725881, Proceedings of the National Academy of Sciences of the United States of America, 1991, Mayer, B J; Jackson, P K; Baltimore, D

Nucleus and gene expression
score: 4.9722856, Current Opinion in Cell Biology, 1991,

Inhibition of HLA-DR assembly, transport, and loading by human cytomegalovirus glycoprotein US3: a novel mechanism for evading major histocompatibility complex class II antigen presentation.
score: 4.9714546, Journal of virology, 2002, Hegde, Nagendra R et. al.

Kit- and FcɛRI-induced differential phosphorylation of the transmembrane adaptor molecule NTAL/LAB/LAT2 allows flexibility in its scaffolding function in mast cells
score: 4.9706163, Cellular Signalling, 2008, Iwaki, Shoko et. al.

Phosphorylation of ErbB4 on Tyr1056 is critical for inhibition of colony formation by prostate tumor cell lines
score: 4.9676307, Biochemical and Biophysical Research Communications, 2006, Gallo, Richard M. et. al.

The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis.
score: 4.9670089, Molecular and cellular biology, 2002, Kontos, Christopher D et. al.

Negative Regulation of Cytokine and TLR Signalings by SOCS and Others
score: 4.9597453, Advances in Immunology, 2005, Naka, Tetsuji et. al.

Decoding ubiquitin sorting signals for clathrin-dependent endocytosis by CLASPs.
score: 4.9533413, Journal of cell science, 2007, Traub, Linton M; Lukacs, Gergely L

The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation.
score: 4.9522226, The EMBO journal, 1997, Mainiero, F et. al.

Stimulatory function of gp49A, a murine Ig-like receptor, in rat basophilic leukemia cells.
score: 4.9506438, Journal of immunology (Baltimore, Md. : 1950), 2000, Lee, K H; Ono, M; Inui, M; Yuasa, T; Takai, T

Fc gammaRIIIB stimulation promotes beta1 integrin activation in human neutrophils.
score: 4.9450276, Journal of leukocyte biology, 2005, Ortiz-Stern, Alejandro; Rosales, Carlos

Cell and Molecular Biology of Nucleolar Assembly and Disassembly
score: 4.9439459, International Review of Cytology, 2004, DiMario, Patrick J.

Cell and Molecular Biology of Nucleolar Assembly and Disassembly
score: 4.9439459, International Review of Cytology, 2004, DiMario, Patrick J.

NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA.
score: 4.9436156, EMBO reports, 2008, Woeller, Collynn F et. al.

Convergent actions of I kappa B kinase beta and protein kinase C delta modulate mRNA stability through phosphorylation of 14-3-3 beta complexed with tristetraprolin.
score: 4.9375517, Molecular and cellular biology, 2005, Gringhuis, Sonja I et. al.

Intersectin 1 enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of Sprouty2-Cbl interaction.
score: 4.9341559, Molecular and cellular biology, 2012, Okur, Mustafa Nazir et. al.

Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System
score: 4.9297493, Clinical Medicine Insights. Oncology, 2011, Nieto-Sampedro, Manuel et. al.

Increased in vivo phosphorylation of ret tyrosine 1062 is a potential pathogenetic mechanism of multiple endocrine neoplasia type 2B.
score: 4.9293323, Cancer research, 2001, Salvatore, D et. al.

Mechanism of action of platelet-derived growth factor
score: 4.9266459, International Journal of Biochemistry and Cell Biology, 1996, Claesson-Welsh, Lena

Regulation of VEGF signaling by membrane traffic
score: 4.9232045, Cellular Signalling, 2012, Horowitz, Arie; Seerapu, Himabindu Reddy

Regulation of VEGF signaling by membrane traffic
score: 4.9232045, Cellular Signalling, 2012, Horowitz, Arie; Seerapu, Himabindu Reddy

Multiple Processing Body Factors and the ARE Binding Protein TTP Activate mRNA Decapping
score: 4.9213777, Molecular Cell, 2005, Fenger-Grøn, Martin et. al.

The PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1.
score: 4.9213102, The EMBO journal, 2010, Smith, Matthew J et. al.

Molecular aspects of medicine: from experimental to clinical hepatology
score: 4.920426, Molecular Aspects of Medicine, 2004, Häussinger, Dieter et. al.

Reaching a Genetic and Molecular Understanding of Skeletal Development
score: 4.9198886, Developmental Cell, 2002, Karsenty, Gerard; Wagner, Erwin F.

Dismantling Cell–Cell Contacts during Apoptosis Is Coupled to a Caspase-dependent Proteolytic Cleavage of β-Catenin
score: 4.9197371, The Journal of Cell Biology, 1997, Brancolini, Claudio et. al.

Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.
score: 4.9180915, Molecular and cellular biology, 1994, Noguchi, T; Matozaki, T; Horita, K; Fujioka, Y; Kasuga, M

Phospholipase C-γ2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen
score: 4.9140304, The Journal of Experimental Medicine, 2008, Weber, Michele et. al.

Dok-R mediates attenuation of epidermal growth factor-dependent mitogen-activated protein kinase and Akt activation through processive recruitment of c-Src and Csk.
score: 4.9122563, Molecular and cellular biology, 2005, Van Slyke, Paul et. al.

The many facets of Notch ligands.
score: 4.9117487, Oncogene, 2008, D'Souza, B; Miyamoto, A; Weinmaster, G

SNAREs and membrane fusion in the Golgi apparatus
score: 4.9114724, BBA - Molecular Cell Research, 1998, Nichols, Benjamin J; Pelham, Hugh R.B

Studies of the regulation and function of the G sα gene Gnas using gene targeting technology
score: 4.9102592, Pharmacology and Therapeutics, 2007, Weinstein, Lee S.; Xie, Tao; Zhang, Qing-Hong; Chen, Min

Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation.
score: 4.9087031, Molecular and cellular biology, 2000, Filippa, N; Sable, C L; Hemmings, B A; Van Obberghen, E

Transmembrane adapters: structure, biochemistry and biology
score: 4.9059387, Seminars in Immunology, 2004, Kliche, Stefanie; Lindquist, Jonathan A.; Schraven, Burkhart

The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42
score: 4.9032598, The Journal of Cell Biology, 2007, Rosário, Marta et. al.

ErbB4 splice variants Cyt1 and Cyt2 differ by 16 amino acids and exert opposing effects on the mammary epithelium in vivo.
score: 4.9019286, Molecular and cellular biology, 2009, Muraoka-Cook, Rebecca S et. al.

Identification of PECAM-1 association with sphingosine kinase 1 and its regulation by agonist-induced phosphorylation
score: 4.8988084, BBA - Molecular and Cell Biology of Lipids, 2004, Fukuda, Yu; Aoyama, Yuki; Wada, Atsushi; Igarashi, Yasuyuki

Tyr130 phosphorylation triggers Syk release from antigen receptor by long-distance conformational uncoupling.
score: 4.8985514, Proceedings of the National Academy of Sciences of the United States of America, 2008, Zhang, Yajie et. al.

Taming the PI3K team to hold inflammation and cancer at bay
score: 4.8971802, Pharmacology and Therapeutics, 2008, Hirsch, Emilio et. al.

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression.
score: 4.8962909, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Wenger, Roland H

Gene expression, biological effects and clinical aspects of lymphokines
score: 4.8962876, Critical Reviews in Oncology and Hematology, 1997, Tuyt, Leonore M.L.; Dokter, Willem H.A.; Vellenga, Edo

How Do Lymphocytes Know Where to Go: Current Concepts and Enigmas of Lymphocyte Homing
score: 4.893516, Advances in Immunology, 1997, Salmi, Marko; Jalkanen, Sirpa

How Do Lymphocytes Know Where to Go: Current Concepts and Enigmas of Lymphocyte Homing
score: 4.893516, Advances in Immunology, 1997, Salmi, Marko; Jalkanen, Sirpa

Proteins related to the Nedd4 family of ubiquitin protein ligases interact with the L domain of Rous sarcoma virus and are required for gag budding from cells.
score: 4.8889473, Proceedings of the National Academy of Sciences of the United States of America, 2001, Kikonyogo, A et. al.

Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation.
score: 4.8864676, Oncogene, 2004, Bahassi, El Mustapha et. al.

Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.
score: 4.886023, Molecular systems biology, 2009, Persaud, Avinash et. al.

E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates.
score: 4.8841969, Infection and immunity, 2010, Ensminger, Alexander W; Isberg, Ralph R

Activation and inhibition of erythropoietin receptor function: role of receptor dimerization.
score: 4.8834749, Molecular and cellular biology, 1994, Watowich, S S; Hilton, D J; Lodish, H F

LIME, a Novel Transmembrane Adaptor Protein, Associates with p56 lck and Mediates T Cell Activation
score: 4.8787651, The Journal of Experimental Medicine, 2003, Hur, Eun Mi et. al.

Cytokines in neural regeneration
score: 4.8763346, Current Opinion in Neurobiology, 1992, Unsicker, Klaus et. al.

Shc associates with the IL-3 receptor β subunit, SHIP and Gab2 following IL-3 stimulation
score: 4.8751443, Cellular Signalling, 2000, Bone, Heather; Welham, Melanie J.

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control.
score: 4.8716182, Molecular and cellular biology, 1998, Shi, Y et. al.

Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer
score: 4.8621567, Breast Cancer Research : BCR, 2011, Miller, Todd W et. al.

Crystal structures of the N-terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors.
score: 4.8619291, Protein science : a publication of the Protein Society, 2007, Ikuta, Mari et. al.

Prolonged vs transient roles for early cell cycle signaling components.
score: 4.8616089, Oncogene, 1998, Rose, D W; Xiao, S; Pillay, T S; Kolch, W; Olefsky, J M

Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF.
score: 4.8607704, The EMBO journal, 1997, Schneller, M; Vuori, K; Ruoslahti, E

Development
score: 4.8585958, Current Opinion in Neurobiology, 1996,

Searching new targets for anticancer drug design: The families of Ras and Rho GTPases and their effectors
score: 4.8562982, Progress in Nucleic Acid Research and Molecular Biology, 2001, Aznar, Salvador; Lacal, Juan Carlos

Caspase and calpain substrates: roles in synaptic plasticity and cell death.
score: 4.855811, Journal of neuroscience research, 1999, Chan, S L; Mattson, M P

TNF receptor-associated factor-1 (TRAF1) negatively regulates Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF)-mediated signaling.
score: 4.8550208, European journal of immunology, 2006, Su, Xiaoqin et. al.

P110delta, a novel phosphoinositide 3-kinase in leukocytes.
score: 4.8546022, Proceedings of the National Academy of Sciences of the United States of America, 1997, Vanhaesebroeck, B et. al.

A role for ubiquitin ligase recruitment in retrovirus release.
score: 4.8535332, Proceedings of the National Academy of Sciences of the United States of America, 2000, Strack, B et. al.

G protein-coupled receptors: Dominant players in cell-cell communication
score: 4.8512695, International Review of Cytology, 2002, Bockaert, Joël et. al.

G protein-coupled receptors: Dominant players in cell-cell communication
score: 4.8512695, International Review of Cytology, 2002, Bockaert, Joël et. al.

The Regulation of Oocyte Maturation
score: 4.8504199, Current Topics in Developmental Biology, 2003, Voronina, Ekaterina; Wessel, Gary M

Modulation of TRAIL Signaling Complex
score: 4.849834, Vitamins and Hormones, 2004, Hao, Chunhai et. al.

Mechanisms and Consequences of Neutrophil Interaction with the Endothelium
score: 4.8482544, The American Journal of Pathology, 2008, Zarbock, Alexander; Ley, Klaus

Importance of the membrane-proximal extracellular domains for activation of the signal transducer glycoprotein 130.
score: 4.8468904, Journal of immunology (Baltimore, Md. : 1950), 2000, Kurth, I et. al.

Characterization of a calmodulin kinase II inhibitor protein in brain.
score: 4.843261, Proceedings of the National Academy of Sciences of the United States of America, 1998, Chang, B H; Mukherji, S; Soderling, T R

VEGF receptor signalling - in control of vascular function.
score: 4.8393754, Nature reviews. Molecular cell biology, 2006, Olsson, Anna-Karin et. al.

Soluble adhesion molecules in human cancers: Sources and fates
score: 4.8390031, European Journal of Cell Biology, 2010, van Kilsdonk, Jeroen W.J. et. al.

Right time, right place: the organization of membrane proximal signaling
score: 4.8310294, Seminars in Immunology, 2005, Simeoni, Luca et. al.

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha.
score: 4.8293239, Molecular and cellular biology, 2001, Heissmeyer, V; Krappmann, D; Hatada, E N; Scheidereit, C

Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF Fbw7
score: 4.8292127, Cell Metabolism, 2005, Sundqvist, Anders et. al.

Essential Role for IκB Kinase β in Remodeling Carma1-Bcl10-Malt1 Complexes upon T Cell Activation
score: 4.8202022, Molecular Cell, 2006, Wegener, Elmar et. al.

Caspase structure, proteolytic substrates, and function during apoptotic cell death.
score: 4.8179815, Cell death and differentiation, 1999, Nicholson, D W

The multifaceted roles of the receptor tyrosine kinase ROS in development and cancer
score: 4.8141796, BBA - Reviews on Cancer, 2009, Acquaviva, Jaime; Wong, Ricky; Charest, Al

The multifaceted roles of the receptor tyrosine kinase ROS in development and cancer
score: 4.8141796, BBA - Reviews on Cancer, 2009, Acquaviva, Jaime; Wong, Ricky; Charest, Al

Channel catfish leukocyte immune-type receptor mediated inhibition of cellular cytotoxicity is facilitated by SHP-1-dependent and -independent mechanisms
score: 4.8126073, Developmental and Comparative Immunology, 2012, Montgomery, Benjamin C. et. al.

Finding the weakest link: exploring integrin-mediated mechanical molecular pathways.
score: 4.8111125, Journal of cell science, 2012, Roca-Cusachs, Pere; Iskratsch, Thomas; Sheetz, Michael P

Shp-2 Tyrosine Phosphatase: Signaling One Cell or Many
score: 4.8061455, Experimental Cell Research, 1999, Feng, Gen-Sheng

A link between MAP kinase and p34(cdc2)/cyclin B during oocyte maturation: p90(rsk) phosphorylates and inactivates the p34(cdc2) inhibitory kinase Myt1.
score: 4.8042635, The EMBO journal, 1998, Palmer, A; Gavin, A C; Nebreda, A R

Natural killer cell receptor signaling
score: 4.802864, Current Opinion in Immunology, 2003, Lanier, Lewis L

Crystal Structure of the Caenorhabditis elegans Apoptosome Reveals an Octameric Assembly of CED-4
score: 4.8022687, Cell, 2010, Qi, Shiqian et. al.

Translational control by cytoplasmic polyadenylation in Xenopus oocytes
score: 4.8003152, BBA - Gene Regulatory Mechanisms, 2008, Radford, Helois E.; Meijer, Hedda A.; de Moor, Cornelia H.

Translational control by cytoplasmic polyadenylation in Xenopus oocytes
score: 4.8003152, Biochimica et Biophysica Acta, 2008, Radford, Helois E.; Meijer, Hedda A.; de Moor, Cornelia H.

Review of the recently defined molecular mechanisms underlying thanatophoric dysplasia and their potential therapeutic implications for achondroplasia.
score: 4.7997737, American journal of medical genetics. Part A, 2010, Martínez-Frías, María Luisa et. al.

The cytoskeleton in lymphocyte signaling
score: 4.7940904, Advances in Immunology, 2000, Bauch, A.; Alt, F.W.; Crabtree, G.R.; Snapper, S.B.

Point mutations in the α2 domain of HLA-A2.1 define a functionally relevant interaction with TAP
score: 4.7930582, Current Biology, 1996, Lewis, Jonathan W et. al.

Regulation of Raf-1 by Direct Feedback Phosphorylation
score: 4.7927526, Molecular Cell, 2005, Dougherty, Michele K. et. al.

SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
score: 4.7892095, Cell, 1993, Yokoyama, Chieko et. al.

Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome.
score: 4.7887293, Molecular and cellular biology, 2001, Kiernan, R E et. al.

TLR9 as a key receptor for the recognition of DNA
score: 4.7875445, Advanced Drug Delivery Reviews, 2008, Kumagai, Yutaro; Takeuchi, Osamu; Akira, Shizuo

The Ubiquitin Ligase TRIM56 Regulates Innate Immune Responses to Intracellular Double-Stranded DNA
score: 4.7868124, Immunity, 2010, Tsuchida, Tetsuo et. al.

Peptide library screening for determination of SH2 or phosphotyrosine-binding domain sequences
score: 4.7858724, Methods in Enzymology, 2001, Songyang, Zhou; Liu, Dan

Peptide library screening for determination of SH2 or phosphotyrosine-binding domain sequences
score: 4.7858724, Methods in Enzymology, 2001, Songyang, Zhou; Liu, Dan

Negative regulation of urokinase-type plasminogen activator production through FGF-2-mediated activation of phosphoinositide 3-kinase.
score: 4.78526, Oncogene, 2002, Mochizuki, Yasushi et. al.

Roles for the ubiquitin–proteasome pathway in protein quality control and signaling in the retina: Implications in the pathogenesis of age-related macular degeneration
score: 4.7850372, Molecular Aspects of Medicine, 2012, Shang, Fu; Taylor, Allen

Roles for the ubiquitin–proteasome pathway in protein quality control and signaling in the retina: Implications in the pathogenesis of age-related macular degeneration
score: 4.7850372, Molecular Aspects of Medicine, 2012, Shang, Fu; Taylor, Allen

Roles for the ubiquitin–proteasome pathway in protein quality control and signaling in the retina: Implications in the pathogenesis of age-related macular degeneration
score: 4.7850372, Molecular Aspects of Medicine, 2012, Shang, Fu; Taylor, Allen

CD2AP/SHIP1 complex positively regulates plasmacytoid dendritic cell receptor signaling by inhibiting the E3 ubiquitin ligase Cbl.
score: 4.784383, Journal of immunology (Baltimore, Md. : 1950), 2012, Bao, Musheng et. al.

Signaling to gene activation and cell death by tumor necrosis factor receptors and fas
score: 4.7831447, International Review of Cytology, 2002, Beyaert, Rudi et. al.

A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments
score: 4.7830208, The Journal of Cell Biology, 1995,

Antiviral NK cell responses in HIV infection: II. viral strategies for evasion and lessons for immunotherapy and vaccination.
score: 4.7788636, Journal of leukocyte biology, 2008, Iannello, Alexandre et. al.

Beyond oxygen: complex regulation and activity of hypoxia inducible factors in pregnancy
score: 4.7758644, Human Reproduction Update, 2009, Pringle, K.G. et. al.

Src Family Tyrosine Kinases and Growth Factor Signaling
score: 4.7756242, Experimental Cell Research, 2000, Abram, Clare L.; Courtneidge, Sara A.

HERC3 binding to and regulation by ubiquitin
score: 4.7706882, FEBS Letters, 2001, Cruz, Cristina et. al.

c-Fes tyrosine kinase binds to and activates STAT3 after granulocyte–macrophage colony-stimulating factor stimulation
score: 4.7669603, Cancer Letters, 1998, Park, Woong-Yang et. al.

Gene organization and evolution
score: 4.7665021, Current Opinion in Genetics & Development, 1991,

Fc epsilon RI-mediated tyrosine phosphorylation and activation of the 72-kDa protein-tyrosine kinase, PTK72, in RBL-2H3 rat tumor mast cells.
score: 4.7664281, Proceedings of the National Academy of Sciences of the United States of America, 1992, Hutchcroft, J E; Geahlen, R L; Deanin, G G; Oliver, J M

A unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and function.
score: 4.7611409, Molecular and cellular biology, 2003, Jones, Nina et. al.

Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1.
score: 4.7568719, Molecular and cellular biology, 2005, Arnold, Rüdiger et. al.

Janus kinase 2 activation by the platelet-activating factor receptor (PAFR): roles of Tyk2 and PAFR C terminus.
score: 4.7561999, Journal of immunology (Baltimore, Md. : 1950), 2003, Lukashova, Viktoria et. al.

The Polycomb-associated protein Rybp is a ubiquitin binding protein
score: 4.7532641, FEBS Letters, 2006, Arrigoni, Rachele et. al.

Genomewide Expression Analysis in Zebrafish mind bomb Alleles with Pancreas Defects of Different Severity Identifies Putative Notch Responsive Genes
score: 4.7531593, PLoS ONE, 2008, Hegde, Ashok et. al.

Direct binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activation.
score: 4.7521444, Molecular and cellular biology, 2002, Pak, Youngshil; Pham, Nam; Rotin, Daniela

Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response
score: 4.7515381, Cell, 2006, Zhang, Kezhong et. al.

Lymphocyte activation and effector functions
score: 4.7508015, Current Opinion in Immunology, 1991,

31st annual meeting of the British Association of Cancer Research and the 5th annual meeting of the Association of Cancer Physicians. 19-22 March 1990, Sussex, UK. Abstracts.
score: 4.748572, British Journal of Cancer, 1990,

Notch signaling as a therapeutic target
score: 4.7476834, Current Opinion in Chemical Biology, 2002, Nam, Yunsun; Aster, Jon C; Blacklow, Stephen C

Bibliography of the current world literature
score: 4.7475754, Current Opinion in Biotechnology, 1990,

Multisite Phosphorylation by Cdk2 and GSK3 Controls Cyclin E Degradation
score: 4.7454588, Molecular Cell, 2003, Welcker, Markus et. al.

Natural killer cell receptors: Regulating innate immune responses to hematologic malignancy
score: 4.7396343, Seminars in Hematology, 2005, Hsu, Katharine C.; Dupont, Bo

BRD4 is an atypical kinase that phosphorylates Serine2 of the RNA Polymerase II carboxy-terminal domain.
score: 4.7364269, Proceedings of the National Academy of Sciences of the United States of America, 2012, Devaiah, Ballachanda N et. al.

Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras.
score: 4.7359737, Molecular and cellular biology, 2003, Marty, Caroline; Browning, Darren D; Ye, Richard D

Human T-Cell Lymphotropic Virus: A Model of NF-κB-Associated Tumorigenesis
score: 4.7328947, Viruses, 2011, Qu, Zhaoxia; Xiao, Gutian

Integrin α2β1 Mediates Isoform-Specific Activation of p38 and Upregulation of Collagen Gene Transcription by a Mechanism Involving the α2 Cytoplasmic Tail
score: 4.731369, The Journal of Cell Biology, 1999, Ivaska, Johanna et. al.

Perspectives on PKCθ in T cell activation
score: 4.7310982, Molecular Immunology, 2004, Sedwick, Caitlin E; Altman, Amnon

The Cbl Family and Other Ubiquitin Ligases
score: 4.7288236, Immunity, 2004, Duan, Lei et. al.

Cell signalling cascades regulating neuronal growth-promoting and inhibitory cues
score: 4.7252918, Progress in Neurobiology, 2001, Skaper, Stephen D; Moore, Stephen E; Walsh, Frank S

Neurotrophin signaling through the p75 neurotrophin receptor
score: 4.7232441, Progress in Neurobiology, 2002, Roux, Philippe P; Barker, Philip A

Engineering and design
score: 4.7214479, Current Opinion in Structural Biology, 1995,

Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b.
score: 4.7173049, Oncogene, 2004, Davies, Gareth C et. al.

Differential interaction of Cbl with Grb2 and CrkL in CD2-mediated NK cell activation
score: 4.7125684, Molecular Immunology, 2000, Huang, Jian-Yong et. al.

Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries.
score: 4.7089958, Proceedings of the National Academy of Sciences of the United States of America, 1998, Hanes, J et. al.

Raf kinases mediate the phosphorylation of eukaryotic translation elongation factor 1A and regulate its stability in eukaryotic cells
score: 4.7083953, Cell Death & Disease, 2012, Sanges, C et. al.

The Role of the Conserved Switch II Glutamate in Guanine Nucleotide Exchange Factor-Mediated Nucleotide Exchange of GTP-Binding Proteins
score: 4.7080453, Journal of Molecular Biology, 2008, Gasper, Raphael et. al.

Regulation of the Jak2 tyrosine kinase by its pseudokinase domain.
score: 4.7076398, Molecular and cellular biology, 2000, Saharinen, P; Takaluoma, K; Silvennoinen, O

The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase.
score: 4.7068614, Proceedings of the National Academy of Sciences of the United States of America, 1996, Damen, J E et. al.

The nonreceptor protein-tyrosine kinase CSK complexes directly with the GTPase-activating protein-associated p62 protein in cells expressing v-Src or activated c-Src.
score: 4.705617, Molecular and cellular biology, 1995, Neet, K; Hunter, T

Direct and Regulated Interaction of Integrin α E β 7 with E-Cadherin
score: 4.6996079, The Journal of Cell Biology, 1998, Higgins, Jonathan M.G. et. al.

Crystal Structure of the Tyrosine Phosphatase SHP-2
score: 4.6993231, Cell, 1998, Hof, Peter et. al.

Antigen Presentation and the Ubiquitin‐Proteasome System in Host–Pathogen Interactions
score: 4.6976701, Advances in Immunology, 2006, Loureiro, Joana; Ploegh, Hidde L.

Antigen Presentation and the Ubiquitin‐Proteasome System in Host–Pathogen Interactions
score: 4.6976701, Advances in Immunology, 2006, Loureiro, Joana; Ploegh, Hidde L.

Differential Requirement for LAT and SLP-76 in GPVI versus T Cell Receptor Signaling
score: 4.6970622, The Journal of Experimental Medicine, 2002, Judd, Barbi A. et. al.

Line of attack: NK cell specificity and integration of signals
score: 4.6942862, Current Opinion in Immunology, 2008, Bryceson, Yenan T; Long, Eric O

Allele- and locus-specific recognition of class I MHC molecules by the immunomodulatory E3-19K protein from adenovirus.
score: 4.6922422, Journal of immunology (Baltimore, Md. : 1950), 2007, Liu, Hong; Fu, Jie; Bouvier, Marlene

Role of Transcription Factor Modifications in the Pathogenesis of Insulin Resistance
score: 4.6911871, Experimental Diabetes Research, 2011, Kim, Mi-Young et. al.

CD38 signal transduction in human B cell precursors. Rapid induction of tyrosine phosphorylation, activation of syk tyrosine kinase, and phosphorylation of phospholipase C-gamma and phosphatidylinositol 3-kinase.
score: 4.6901942, Journal of immunology (Baltimore, Md. : 1950), 1996, Silvennoinen, O et. al.

Acidification and Protein Traffic
score: 4.6901459, International Review of Cytology, 2003, Weisz, Ora A

Acidification and Protein Traffic
score: 4.6901459, International Review of Cytology, 2003, Weisz, Ora A

Cyclin E in normal and neoplastic cell cycles.
score: 4.6893085, Oncogene, 2005, Hwang, Harry C; Clurman, Bruce E

Membranes
score: 4.6884167, Current Opinion in Cell Biology, 1992,

De-regulated FGF receptors as therapeutic targets in cancer
score: 4.687769, Pharmacology and Therapeutics, 2010, Knights, Victoria; Cook, Simon J.

ErbB4 (JM-b/CYT-1)-induced expression and phosphorylation of c-Jun is abrogated by human papillomavirus type 16 E5 protein.
score: 4.68594, Oncogene, 2007, Chen, S-L; Lin, S-T; Tsai, T-C; Hsiao, W-C; Tsao, Y-P

Ubc9 interacts with a nuclear localization signal and mediates nuclear localization of the paired-like homeobox protein Vsx-1 independent of SUMO-1 modification.
score: 4.6850024, Proceedings of the National Academy of Sciences of the United States of America, 2001, Kurtzman, A L; Schechter, N

A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits.
score: 4.6839749, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Seeger, M et. al.

Tec family kinases in lymphocyte signaling and function
score: 4.6807947, Current Opinion in Immunology, 2000, Schaeffer, Edward M; Schwartzberg, Pamela L

Nuclear transcription factors in the hippocampus
score: 4.6798574, Progress in Neurobiology, 2002, Hinoi, Eiichi et. al.

D1 dopamine receptor signaling involves caveolin-2 in HEK-293 cells.
score: 4.6775801, Kidney international, 2004, Yu, Peiying et. al.

Receptor regulation of phosphoinositidase C
score: 4.676972, Pharmacology and Therapeutics, 1991, Martin, Thomas F.J.

Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway.
score: 4.6692885, Oncogene, 2006, Perkins, N D

Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications
score: 4.6676513, EMBO Molecular Medicine, 2012, Fulda, Simone; Rajalingam, Krishnaraj; Dikic, Ivan

Ubiquitylation in innate and adaptive immunity.
score: 4.666497, Nature, 2009, Bhoj, Vijay G; Chen, Zhijian J

Signaling Takes Shape in the Immune System
score: 4.6589555, Cell, 2000, Dustin, Michael L; Chan, Andrew C

CK2 Phospho-Dependent Binding of R2TP Complex to TEL2 Is Essential for mTOR and SMG1 Stability
score: 4.657848, Molecular Cell, 2010, Hořejší, Zuzana et. al.

CK2 Phospho-Dependent Binding of R2TP Complex to TEL2 Is Essential for mTOR and SMG1 Stability
score: 4.657848, Molecular Cell, 2010, Hořejší, Zuzana et. al.

Activation of Vav by Nef Induces Cytoskeletal Rearrangements and Downstream Effector Functions
score: 4.65723, Molecular Cell, 1999, Fackler, Oliver T et. al.

Downstream of tyrosine kinase/docking protein 6, as a novel substrate of tropomyosin-related kinase C receptor, is involved in neurotrophin 3-mediated neurite outgrowth in mouse cortex neurons
score: 4.6560808, BMC Biology, 2010, Li, Wei qi et. al.

Inhibitory receptors, ITIM sequences and phosphatases
score: 4.6543687, Current Opinion in Immunology, 1997, Unkeless, Jay C; Jin, Jie

Plexin B Mediates Axon Guidance in Drosophila by Simultaneously Inhibiting Active Rac and Enhancing RhoA Signaling
score: 4.6538697, Neuron, 2001, Hu, Hailan; Marton, Tobias F.; Goodman, Corey S.

Structure and Function of Leukocyte Chemoattractant Receptors
score: 4.6520897, Advances in Pharmacology, 1997, Ye, Richard D.; Boulay, Franc¸ois

Angiopoietin 2 stimulates migration and tube-like structure formation of murine brain capillary endothelial cells through c-Fes and c-Fyn.
score: 4.6470617, Journal of cell science, 2002, Mochizuki, Yasushi et. al.

Signal regulatory protein α negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction
score: 4.6462983, Molecular Immunology, 2008, Dong, Li-Wei et. al.

The same epitope on CD22 of B lymphocytes mediates the adhesion of erythrocytes, T and B lymphocytes, neutrophils, and monocytes.
score: 4.6460334, Journal of immunology (Baltimore, Md. : 1950), 1993, Engel, P et. al.

Fibroblast growth factor homologous factor 1 interacts with NEMO to regulate NF-κB signaling in neurons.
score: 4.6431898, Journal of cell science, 2012, König, Hans-Georg et. al.

T Cell Receptor-Interacting Molecule Acts as a Chaperone to Modulate Surface Expression of the CTLA-4 Coreceptor
score: 4.6414856, Immunity, 2006, Valk, Elke et. al.

Ras GTPases: integrins' friends or foes?
score: 4.6385078, Nature reviews. Molecular cell biology, 2003, Kinbara, Kayoko et. al.

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1.
score: 4.6381568, Proceedings of the National Academy of Sciences of the United States of America, 1999, Biggs, W H et. al.

The significance of G protein-coupled receptor crystallography for drug discovery.
score: 4.6377265, Pharmacological reviews, 2011, Salon, John A; Lodowski, David T; Palczewski, Krzysztof

Crystal structure of Ski8p, a WD-repeat protein with dual roles in mRNA metabolism and meiotic recombination.
score: 4.6366038, Protein science : a publication of the Protein Society, 2004, Cheng, Zhihong et. al.

Granulocyte CEACAM3 Is a Phagocytic Receptor of the Innate Immune System that Mediates Recognition and Elimination of Human-specific Pathogens
score: 4.6355444, The Journal of Experimental Medicine, 2004, Schmitter, Tim et. al.

Leptin receptor (OB-R) oligomerizes with itself but not with its closely related cytokine signal transducer gp130
score: 4.635394, FEBS Letters, 1997, Nakashima, Kinichi; Narazaki, Masashi; Taga, Tetsuya

Leptin receptor (OB-R) oligomerizes with itself but not with its closely related cytokine signal transducer gp130
score: 4.635394, FEBS Letters, 1997, Nakashima, Kinichi; Narazaki, Masashi; Taga, Tetsuya

The BAR Domain Protein Arfaptin-1 Controls Secretory Granule Biogenesis at the trans-Golgi Network
score: 4.6351665, Developmental Cell, 2012, Gehart, Helmuth et. al.

The BAR Domain Protein Arfaptin-1 Controls Secretory Granule Biogenesis at the trans-Golgi Network
score: 4.6351665, Developmental Cell, 2012, Gehart, Helmuth et. al.

A Ras activation pathway dependent on Syk phosphorylation of protein kinase C.
score: 4.6344489, Proceedings of the National Academy of Sciences of the United States of America, 2003, Kawakami, Yuko et. al.

Endocytosis and intracellular trafficking of ErbBs
score: 4.6303801, Experimental Cell Research, 2009, Sorkin, Alexander; Goh, Lai Kuan

Inhibition of the anaphase-promoting complex by the Xnf7 ubiquitin ligase
score: 4.6257844, The Journal of Cell Biology, 2005, Casaletto, Jessica B. et. al.

Biopolymers
score: 4.6227024, Current Opinion in Chemical Biology, 1997,

Translocation of the interleukin-1 receptor-associated kinase-1 (IRAK-1) into the nucleus
score: 4.6207896, FEBS Letters, 2000, Böl, G.-F; Kreuzer, O.J; Brigelius-Flohé, R

Disease specificity of kinase domains: the src-encoded catalytic domain converts erbB into a sarcoma oncogene.
score: 4.6195024, Proceedings of the National Academy of Sciences of the United States of America, 1995, Chang, C M; Shu, H K; Kung, H J

Xenopus Cds1 is regulated by DNA-dependent protein kinase and ATR during the cell cycle checkpoint response to double-stranded DNA ends.
score: 4.618223, Molecular and cellular biology, 2004, McSherry, Troy D; Mueller, Paul R

G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia.
score: 4.6177678, Oncogene, 2005, Riz, Irene; Hawley, Robert G

Bovine papillomavirus E5 protein induces oligomerization and trans-phosphorylation of the platelet-derived growth factor beta receptor.
score: 4.6169092, Proceedings of the National Academy of Sciences of the United States of America, 1998, Lai, C C; Henningson, C; DiMaio, D

Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons.
score: 4.6162717, Molecular and cellular biology, 1996, Meinke, A et. al.

Evidence that Myb-related CDC5 proteins are required for pre-mRNA splicing.
score: 4.6153028, Proceedings of the National Academy of Sciences of the United States of America, 1999, Burns, C G; Ohi, R; Krainer, A R; Gould, K L

Bibliography of the current world literature
score: 4.6146529, Current Opinion in Genetics & Development, 1993,

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling
score: 4.6115699, Molecular Cell, 2010, Paquette, Nicholas et. al.

The role of the TRAF-interacting protein in proliferation and differentiation.
score: 4.6104423, Experimental dermatology, 2012, Chapard, Christophe; Hohl, Daniel; Huber, Marcel

syk protein tyrosine kinase regulates Fc receptor gamma-chain-mediated transport to lysosomes.
score: 4.6102414, The EMBO journal, 1998, Bonnerot, C et. al.

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin
score: 4.6099337, The Journal of Cell Biology, 2008, Melander, Fredrik et. al.

Molecular Mechanism of Multivesicular Body Biogenesis by ESCRT Complexes
score: 4.6091534, Nature, 2010, Wollert, Thomas; Hurley, James H.

Plasmin-Sensitive Dibasic Sequences in the Third Fibronectin-like Domain of L1–Cell Adhesion Molecule (Cam) Facilitate Homomultimerization and Concomitant Integrin Recruitment
score: 4.6089296, The Journal of Cell Biology, 2000, Silletti, Steve et. al.

c-Myc in the Controlm of Cell Proliferation and Embryonic Development
score: 4.607222, Advances in Cancer Research, 1996, Lemaitre, Jean-Marc; Buckle, Robin S.; Méchali, Marcel

Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.
score: 4.6035991, Molecular and cellular biology, 1999, Kim, H; Baumann, H

Meiotic Inactivation of Xenopus Myt1 by CDK/XRINGO, but Not CDK/Cyclin, via Site-Specific Phosphorylation
score: 4.6034193, Molecular Cell, 2008, Ruiz, E. Josué; Hunt, Tim; Nebreda, Angel R.

CDC42 and FGD1 cause distinct signaling and transforming activities.
score: 4.6023665, Molecular and cellular biology, 1998, Whitehead, I P; Abe, K; Gorski, J L; Der, C J

Isolation, characterization, and expression of cDNAs encoding murine alpha-mannosidase II, a Golgi enzyme that controls conversion of high mannose to complex N-glycans
score: 4.5999229, The Journal of Cell Biology, 1991,

Reconstitution of receptor/GTP-binding protein interactions
score: 4.5967526, BBA - Reviews on Biomembranes, 1991, Cerione, Richard A.

Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.
score: 4.5930278, Molecular and cellular biology, 2002, Loreto, Michael P; Berry, Donna M; McGlade, C Jane

Sequential requirements of the N-terminal palmitoylation site and SH2 domain of Src family kinases in the initiation and progression of FcepsilonRI signaling.
score: 4.5930154, Molecular and cellular biology, 2000, Honda, Z i et. al.

TSH-activated signaling pathways in thyroid tumorigenesis
score: 4.5910753, Molecular and Cellular Endocrinology, 2003, Rivas, Marcos; Santisteban, Pilar

The Amino-terminal Domain of Desmoplakin Binds to Plakoglobin and Clusters Desmosomal Cadherin–Plakoglobin Complexes
score: 4.5905381, The Journal of Cell Biology, 1997, Kowalczyk, Andrew P. et. al.

TAM Receptor Tyrosine Kinases: Biologic Functions, Signaling, and Potential Therapeutic Targeting in Human Cancer
score: 4.5871312, Advances in Cancer Research, 2008, Linger, Rachel M.A. et. al.

Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration.
score: 4.5868265, Journal of cell science, 2010, Pan, Catherine Qiurong; Liou, Yih-Cherng; Low, Boon Chuan

ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration
score: 4.5827206, The Journal of Cell Biology, 2008, Yamauchi, Junji et. al.

Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system
score: 4.5812757, Cell, 1991, López-Casillas, Fernando et. al.

Notch: The Past, the Present, and the Future
score: 4.5796217, Current Topics in Developmental Biology, 2010, Artavanis-Tsakonas, Spyros; Muskavitch, Marc A.T.

Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes.
score: 4.5796148, Proceedings of the National Academy of Sciences of the United States of America, 2002, Hook, Sara S et. al.

SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors.
score: 4.5796112, Molecular and cellular biology, 1992, McGlade, C J et. al.

A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction.
score: 4.5790531, Journal of immunology (Baltimore, Md. : 1950), 1999, Newton-Nash, D K; Newman, P J

Nucleus and gene expression
score: 4.5779644, Current Opinion in Cell Biology, 1990,

A Novel Lysosome-Associated Membrane Glycoprotein, DC-LAMP, Induced upon DC Maturation, Is Transiently Expressed in MHC Class II Compartment
score: 4.576869, Immunity, 1998, de Saint-Vis, B et. al.

Evidence for evolving Toll-IL-1 receptor-containing adaptor molecule function in vertebrates.
score: 4.5752161, Journal of immunology (Baltimore, Md. : 1950), 2007, Sullivan, Con et. al.

A unique insert in the linker domain of Syk is necessary for its function in immunoreceptor signalling.
score: 4.5734616, The EMBO journal, 1998, Latour, S; Zhang, J; Siraganian, R P; Veillette, A

A Requirement for Caveolin-1 and Associated Kinase Fyn in Integrin Signaling and Anchorage-Dependent Cell Growth
score: 4.5707696, Cell, 1998, Wary, Kishore K et. al.

Advances in research of fish immune-relevant genes: A comparative overview of innate and adaptive immunity in teleosts
score: 4.5652967, Developmental and Comparative Immunology, 2013, Zhu, Lv-yun et. al.

The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking
score: 4.5633754, The Journal of Cell Biology, 2009, Francavilla, Chiara et. al.

Ras activity regulates cyclin E degradation by the Fbw7 pathway.
score: 4.5596398, Proceedings of the National Academy of Sciences of the United States of America, 2005, Minella, Alex C; Welcker, Markus; Clurman, Bruce E

The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells.
score: 4.5593974, Cancer research, 1997, Poon, R Y; Chau, M S; Yamashita, K; Hunter, T

Receptor-Specific Mechanisms Regulate Phosphorylation of AKT at Ser473: Role of RICTOR in β1 Integrin-Mediated Cell Survival
score: 4.5566382, PLoS ONE, 2012, Riaz, Anjum; Zeller, Kathrin Stephanie; Johansson, Staffan

Analysis of mutations in fibroblast growth factor (FGF) and a pathogenic mutation in FGF receptor (FGFR) provides direct evidence for the symmetric two-end model for FGFR dimerization.
score: 4.5528841, Molecular and cellular biology, 2005, Ibrahimi, Omar A et. al.

Sequences and topology
score: 4.5512362, Current Opinion in Structural Biology, 1996,

TRIF-GEFH1-RhoB pathway is involved in MHCII expression on dendritic cells that is critical for CD4 T-cell activation.
score: 4.5463631, The EMBO journal, 2006, Kamon, Hokuto et. al.

Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1.
score: 4.5459139, Oncogene, 2005, Cornelis, Sigrid et. al.

The Ras suppressor Rsu-1 binds to the LIM 5 domain of the adaptor protein PINCH1 and participates in adhesion-related functions
score: 4.5409884, Experimental Cell Research, 2005, Dougherty, Gerard W. et. al.

Structural and functional coupling of Hsp90- and Sgt1-centred multi-protein complexes.
score: 4.540171, The EMBO journal, 2008, Zhang, Minghao et. al.

Molecular controls of antigen receptor clustering and autoimmunity
score: 4.5397686, Trends in Cell Biology, 2001, Krawczyk, Connie; Penninger, Josef M.

Phosphatidylinositol 3'-kinase and SH2-containing inositol phosphatase (SHIP) are recruited by distinct positive and negative growth-regulatory domains in the granulocyte colony-stimulating factor receptor.
score: 4.5393547, Journal of immunology (Baltimore, Md. : 1950), 1998, Hunter, M G; Avalos, B R

Interleukin-7: physiological roles and mechanisms of action
score: 4.5373884, Cytokine and Growth Factor Reviews, 1999, Hofmeister, R. et. al.

Mad2 transiently associates with an APC/p55Cdc complex during mitosis.
score: 4.535974, Proceedings of the National Academy of Sciences of the United States of America, 1998, Wassmann, K; Benezra, R

Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development.
score: 4.5350193, Molecular and cellular biology, 1997, Meisner, H et. al.

Regulated Step in Cholesterol Feedback Localized to Budding of SCAP from ER Membranes
score: 4.5339902, Cell, 2000, Nohturfft, Axel et. al.

Calcium Release at Fertilization of Xenopus Eggs Requires Type I IP 3 Receptors, but Not SH2 Domain-Mediated Activation of PLCγ or G q-Mediated Activation of PLCβ
score: 4.531056, Developmental Biology, 1999, Runft, Linda L; Watras, James; Jaffe, Laurinda A

Commuting between Golgi cisternae—Mind the GAP!
score: 4.531011, BBA - Molecular Cell Research, 2005, Kartberg, Fredrik et. al.

Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression.
score: 4.5288786, Journal of cell science, 2008, Waldeck-Weiermair, Markus et. al.

Integrin regulation
score: 4.5268464, Current Opinion in Cell Biology, 2005, Ginsberg, Mark H; Partridge, Anthony; Shattil, Sanford J

Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system.
score: 4.5202995, Molecular and cellular biology, 1994, O'Neill, T J; Craparo, A; Gustafson, T A

Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1.
score: 4.5199335, Nature structural & molecular biology, 2006, Houtman, Jon C D et. al.

Dcp2 phosphorylation by Ste20 modulates stress granule assembly and mRNA decay in Saccharomyces cerevisiae
score: 4.5177066, The Journal of Cell Biology, 2010, Yoon, Je-Hyun; Choi, Eui-Ju; Parker, Roy

PKB/Akt interacts with inosine-5′ monophosphate dehydrogenase through its pleckstrin homology domain
score: 4.5174977, FEBS Letters, 2000, Ingley, Evan; Hemmings, Brian A.

Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry.
score: 4.5168022, The EMBO journal, 2000, Ajuh, P et. al.

The ubiquitin E3 ligase activity of BRCA1 and its biological functions
score: 4.5164957, Cell Division, 2008, Wu, Wenwen; Koike, Ayaka; Takeshita, Takashi; Ohta, Tomohiko

Evidence for structural constraint on ovulin, a rapidly evolving Drosophila melanogaster seminal protein.
score: 4.5164246, Proceedings of the National Academy of Sciences of the United States of America, 2006, Wong, Alex; Albright, Shannon N; Wolfner, Mariana F

IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29.
score: 4.5126535, Journal of immunology (Baltimore, Md. : 1950), 2005, Sirén, Jukka et. al.

Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation
score: 4.5120786, Cytokine and Growth Factor Reviews, 1999, Grimley, Philip M.; Dong, Fan; Rui, Hallgeir

Vav3 regulates osteoclast function and bone mass.
score: 4.5118896, Nature medicine, 2005, Faccio, Roberta et. al.

Contents
score: 4.5114184, Current Opinion in Neurobiology, 1991,

Basal phosphorylation of the PEST domain in the I(kappa)B(beta) regulates its functional interaction with the c-rel proto-oncogene product.
score: 4.5096066, Molecular and cellular biology, 1996, Chu, Z L; McKinsey, T A; Liu, L; Qi, X; Ballard, D W

Purification and cDNA cloning of a second apoptosis-related cysteine protease that cleaves and activates sterol regulatory element binding proteins.
score: 4.5062179, Proceedings of the National Academy of Sciences of the United States of America, 1996, Pai, J T; Brown, M S; Goldstein, J L

Toll receptors and pathogen resistance.
score: 4.5049582, Cellular microbiology, 2003, Takeda, Kiyoshi; Akira, Shizuo

Vesicular transport and the golgi apparatus in yeast
score: 4.5034609, Journal of Bioscience and Bioengineering, 2001, Yoda, Koji; Noda, Yoichi

A Cdo–Bnip-2–Cdc42 signaling pathway regulates p38α/β MAPK activity and myogenic differentiation
score: 4.5022328, The Journal of Cell Biology, 2008, Kang, Jong-Sun et. al.

Intracellular Cell-Autonomous Association of Notch and Its Ligands: A Novel Mechanism of Notch Signal Modification
score: 4.5006204, Developmental Biology, 2002, Sakamoto, Kei et. al.

Transcriptional signaling by double-stranded RNA: role of TLR3
score: 4.4988846, Cytokine and Growth Factor Reviews, 2005, Sen, Ganes C.; Sarkar, Saumendra N.

Dual role for TGF-β1 in apoptosis
score: 4.4981116, Cytokine and Growth Factor Reviews, 2005, Sánchez-Capelo, Amelia

The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis.
score: 4.4978257, Proceedings of the National Academy of Sciences of the United States of America, 1999, Laporte, S A et. al.

Cyclic AMP and protein kinase A stimulate Cdc42: role of A(2) adenosine receptors in human mast cells.
score: 4.4954128, Molecular pharmacology, 2000, Feoktistov, I; Goldstein, A E; Biaggioni, I

Protein tyrosine phosphatases in signal transduction
score: 4.4946193, Current Opinion in Cell Biology, 1997, Neel, Benjamin G; Tonks, Nicholas K

Nef enhances c-Cbl phosphorylation in HIV-infected CD4 + T lymphocytes
score: 4.4877215, Virology, 2005, Yang, Polung; Henderson, Andrew J.

Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.
score: 4.4866919, Journal of immunology (Baltimore, Md. : 1950), 2007, Cao, Lulu et. al.

Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment
score: 4.4862932, Experimental Cell Research, 2011, Pilecka, Iwona et. al.

Vav1 controls DAP10-mediated natural cytotoxicity by regulating actin and microtubule dynamics.
score: 4.4848688, Journal of immunology (Baltimore, Md. : 1950), 2006, Graham, Daniel B et. al.

Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation.
score: 4.4842969, Molecular and cellular biology, 2000, Becker, E et. al.

Vascular endothelial growth factor (VEGF) signaling in tumor progression
score: 4.483102, Critical Reviews in Oncology and Hematology, 2007, Roskoski, Robert

Drosophila Dok is required for embryonic dorsal closure.
score: 4.4786177, Development (Cambridge, England), 2006, Biswas, Romi; Stein, David; Stanley, E Richard

Neuronal and glial cell biology
score: 4.4760172, Current Opinion in Neurobiology, 1995,

Early steps of retrovirus replicative cycle
score: 4.4718014, Retrovirology, 2004, Nisole, Sébastien; Saïb, Ali

The Stem Cell Factor, its Properties and Potential Role in the Airways
score: 4.4689733, Pulmonary Pharmacology & Therapeutics, 2001, Kassel, Olivier; da Silva, Carla; Frossard, Nelly

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
score: 4.4688968, Current Biology, 1997, Sells, Mary Ann et. al.

The 14-3-3ζ Protein Binds to the Cell Adhesion Molecule L1, Promotes L1 Phosphorylation by CKII and Influences L1-Dependent Neurite Outgrowth
score: 4.4683717, PLoS ONE, 2010, Ramser, Elisa M. et. al.

Notch signaling: simplicity in design, versatility in function.
score: 4.4681001, Development (Cambridge, England), 2011, Andersson, Emma R; Sandberg, Rickard; Lendahl, Urban

A Regulatory Role for Src Homology 2 Domain–Containing Inositol 5′-Phosphatase (Ship) in Phagocytosis Mediated by Fcγ Receptors and Complement Receptor 3 (α M β 2 ; Cd11b/Cd18)
score: 4.4680363, The Journal of Experimental Medicine, 2001, Cox, Dianne et. al.

Hsc70 regulates accumulation of cyclin D1 and cyclin D1-dependent protein kinase.
score: 4.4668009, Molecular and cellular biology, 2003, Diehl, J Alan et. al.

Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus
score: 4.4660747, Current Biology, 1995, Karin, Michael; Hunter, Tony

Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus
score: 4.4660747, Current Biology, 1995, Karin, Michael; Hunter, Tony

Catalase binds Grb2 in tumor cells when stimulated with serum or ligands for integrin receptors
score: 4.46607, Free Radical Biology and Medicine, 2004, Yano, Sumio; Arroyo, Nelly; Yano, Noriko

An unconventional human Ccr4-Caf1 deadenylase complex in nuclear cajal bodies.
score: 4.4659973, Molecular and cellular biology, 2007, Wagner, Eileen; Clement, Sandra L; Lykke-Andersen, Jens

A High-Affinity Arg-X-X-Lys SH3 Binding Motif Confers Specificity for the Interaction between Gads and SLP-76 in T Cell Signaling
score: 4.4659704, Current Biology, 2002, Berry, Donna M. et. al.

A High-Affinity Arg-X-X-Lys SH3 Binding Motif Confers Specificity for the Interaction between Gads and SLP-76 in T Cell Signaling
score: 4.4659704, Current Biology, 2002, Berry, Donna M. et. al.

Components of a Ubiquitin Ligase Complex Specify Polyubiquitination and Intracellular Trafficking of the General Amino Acid Permease
score: 4.4656767, The Journal of Cell Biology, 2001, Helliwell, Stephen B.; Losko, Sascha; Kaiser, Chris A.

Recruitment of Dok-R to the EGF receptor through its PTB domain is required for attenuation of Erk MAP kinase activation
score: 4.4647289, Current Biology, 1999, Jones, Nina; Dumont, Daniel J.

Recruitment of Dok-R to the EGF receptor through its PTB domain is required for attenuation of Erk MAP kinase activation
score: 4.4647289, Current Biology, 1999, Jones, Nina; Dumont, Daniel J.

The role of protease activity in ErbB biology
score: 4.4578793, Experimental Cell Research, 2009, Blobel, Carl P.; Carpenter, Graham; Freeman, Matthew

Cdc1 and the vacuole coordinately regulate Mn2+ homeostasis in the yeast Saccharomyces cerevisiae.
score: 4.4576703, Genetics, 1998, Paidhungat, M; Garrett, S

NK cell recognition of non-classical HLA class I molecules
score: 4.4570774, Seminars in Immunology, 2000, López-Botet,, Miguel et. al.

The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc.
score: 4.4570004, Journal of immunology (Baltimore, Md. : 1950), 1998, Lord, J D; McIntosh, B C; Greenberg, P D; Nelson, B H

Nck and Crk mediate distinct VEGF-induced signaling pathways that serve overlapping functions in focal adhesion turnover and integrin activation
score: 4.4524521, Experimental Cell Research, 2004, Stoletov, Konstantin V.; Gong, Chunhong; Terman, Bruce I.

Signaling from the IL-2 receptor to the nucleus
score: 4.451713, Cytokine and Growth Factor Reviews, 1997, Lin, Jian-Xin; Leonard, Warren J.

T cell activation-induced CrkII binding to the Zap70 protein tyrosine kinase is mediated by Lck-dependent phosphorylation of Zap70 tyrosine 315.
score: 4.451692, Journal of immunology (Baltimore, Md. : 1950), 2005, Gelkop, Sigal et. al.

Synaptic and glial localization of the integrin αv β8 in mouse and rat brain
score: 4.4509482, Brain Research, 1998, Nishimura, Stephen L et. al.

Ligand endocytosis drives receptor dissociation and activation in the Notch pathway.
score: 4.4480167, Development (Cambridge, England), 2000, Parks, A L; Klueg, K M; Stout, J R; Muskavitch, M A

Structural Basis for Phosphodependent Substrate Selection and Orientation by the SCF Cdc4 Ubiquitin Ligase
score: 4.4460916, Cell, 2003, Orlicky, Stephen et. al.

Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis.
score: 4.4443136, The EMBO journal, 2005, Wang, Min; Pickart, Cecile M

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation.
score: 4.4439971, Molecular and cellular biology, 2006, Tzatsos, Alexandros; Kandror, Konstantin V

Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and phospholipase C gamma 1 are required for NF-kappa B activation and lipid raft recruitment of protein kinase C theta induced by T cell costimulation.
score: 4.4413095, Journal of immunology (Baltimore, Md. : 1950), 2003, Dienz, Oliver et. al.

Nuclear β-Arrestin1 Functions as a Scaffold for the Dephosphorylation of STAT1 and Moderates the Antiviral Activity of IFN-γ
score: 4.4377038, Molecular Cell, 2008, Mo, Wei et. al.

Point mutations in the α2 domain of HLA-A2.1 define a functionally relevant interaction with TAP
score: 4.4345314, Current Biology, 1996, Lewis, Jonathan W et. al.

Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase.
score: 4.4335538, Molecular and cellular biology, 2001, Liu, Y; Jenkins, B; Shin, J L; Rohrschneider, L R

Subunits of the heterotrimeric transcription factor NF-Y are imported into the nucleus by distinct pathways involving importin beta and importin 13.
score: 4.4327817, Molecular and cellular biology, 2005, Kahle, Joerg et. al.

A novel druglike spleen tyrosine kinase binder prevents anaphylactic shock when administered orally
score: 4.4324374, The Journal of Allergy and Clinical Immunology, 2008, Mazuc, Elsa et. al.

Post-translational modifications in host cells during bacterial infection
score: 4.4302907, FEBS Letters, 2010, Ribet, David; Cossart, Pascale

Activating and inhibitory receptors of natural killer cells.
score: 4.4298465, Immunology and cell biology, 2011, Pegram, Hollie J et. al.

Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import.
score: 4.4295006, The EMBO journal, 1999, Yang, J; Winkler, K; Yoshida, M; Kornbluth, S

Signalling mechanisms
score: 4.4278906, Current Opinion in Neurobiology, 1996,

NCAM induces CaMKIIα-mediated RPTPα phosphorylation to enhance its catalytic activity and neurite outgrowth
score: 4.4276433, The Journal of Cell Biology, 2008, Bodrikov, Vsevolod et. al.

Differential αv integrin–mediated Ras-ERK signaling during two pathways of angiogenesis
score: 4.4268801, The Journal of Cell Biology, 2003, Hood, John D. et. al.

Tyrosine kinases and their substrates in B lymphocytes.
score: 4.4266484, Immunological reviews, 2009, Kurosaki, Tomohiro; Hikida, Masaki

Proximal signaling events in FcɛRI-mediated mast cell activation
score: 4.4264232, The Journal of Allergy and Clinical Immunology, 2007, Kambayashi, Taku; Koretzky, Gary A.

Modulation of signalling by Sprouty: a developing story.
score: 4.4252194, Nature reviews. Molecular cell biology, 2004, Kim, Hong Joo; Bar-Sagi, Dafna

Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex.
score: 4.4245201, Proceedings of the National Academy of Sciences of the United States of America, 2003, Brzovic, Peter S et. al.

Src-like adaptor protein (SLAP) regulates B cell receptor levels in a c-Cbl-dependent manner.
score: 4.4239023, Proceedings of the National Academy of Sciences of the United States of America, 2006, Dragone, Leonard L et. al.

Membrane permeability
score: 4.4232562, Current Opinion in Cell Biology, 1990,

Ii Chain Controls the Transport of Major Histocompatibility Complex Class II Molecules to and from Lysosomes
score: 4.4185509, The Journal of Cell Biology, 1997, Brachet, Valérie et. al.

Localization of Sed5, a putative vesicle targeting molecule, to the cis- Golgi network involves both its transmembrane and cytoplasmic domains
score: 4.4182727, The Journal of Cell Biology, 1994,

Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor
score: 4.418069, The Journal of Cell Biology, 1991,

Cell differentiation
score: 4.4164972, Current Opinion in Cell Biology, 1995,

Leu-574 of human HIF-1alpha is a molecular determinant of prolyl hydroxylation.
score: 4.4140964, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Kageyama, Yukio et. al.

A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton
score: 4.4128909, Current Biology, 1997, Aspenström, Pontus

Protein Phosphorylation and Signal Transduction
score: 4.4127705, Pharmacology and Therapeutics, 1999, Graves, Jonathan D.; Krebs, Edwin G.

Expression systems
score: 4.4107185, Current Opinion in Biotechnology, 1993,

SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins
score: 4.4099463, Cellular Signalling, 2000, Borinstein, Scott C et. al.

HIV-1 Nef Assembles a Src Family Kinase-ZAP-70/Syk-PI3K Cascade to Downregulate Cell-Surface MHC-I
score: 4.4078918, Cell Host & Microbe, 2007, Hung, Chien-Hui et. al.

TNFR1-induced activation of the classical NF-κB pathway.
score: 4.4027214, The FEBS journal, 2011, Wajant, Harald; Scheurich, Peter

Grb2 associated binder 2 couples B-cell receptor to cell survival
score: 4.3989439, Cellular Signalling, 2009, Maus, Máté et. al.

The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells.
score: 4.3978145, Molecular and cellular biology, 2009, Baker, R G et. al.

Integrin alphaMbeta2 clustering triggers phosphorylation and activation of protein kinase C delta that regulates transcription factor Foxp1 expression in monocytes.
score: 4.396721, Journal of immunology (Baltimore, Md. : 1950), 2010, Xue, Zhi-Hong et. al.

Toll-like receptor downstream signaling
score: 4.3949415, Arthritis Research & Therapy, 2004, Kawai, Taro; Akira, Shizuo

Integrin-mediated Activation of MAP Kinase Is Independent of FAK: Evidence for Dual Integrin Signaling Pathways in Fibroblasts
score: 4.3901286, The Journal of Cell Biology, 1997, Lin, Tsung H. et. al.

JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3
score: 4.3891108, The Journal of Cell Biology, 2005, Sunayama, Jun et. al.

Mapping the distribution of Golgi enzymes involved in the construction of complex oligosaccharides.
score: 4.3886549, Journal of cell science, 1995, Rabouille, C et. al.

Tonic B-cell and viral ITAM signaling: context is everything.
score: 4.388334, Immunological reviews, 2007, Grande, Shannon M et. al.

Tbx5 and Tbx4 transcription factors interact with a new chicken PDZ-LIM protein in limb and heart development
score: 4.3867604, Developmental Biology, 2004, Krause, Ange et. al.

The Role of Growth Factors in Vascular Cell Development and Differentiation
score: 4.3865176, International Review of Cytology, 1995, Moses, Marsha A.; Klagsbrun, Michael; Shing, Yuen

The Role of Growth Factors in Vascular Cell Development and Differentiation
score: 4.3865176, International Review of Cytology, 1995, Moses, Marsha A.; Klagsbrun, Michael; Shing, Yuen

RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells
score: 4.3850704, Molecular Systems Biology, 2012, Chia, Joanne et. al.

Signal Transduction in the Erythropoietin Receptor System
score: 4.3846228, Experimental Cell Research, 1999, Wojchowski, Don M. et. al.

Activation of hypoxia-induced transcription in normoxia
score: 4.3839239, Experimental Cell Research, 2005, Hägg, Maria; Wennström, Stefan

Negative Signaling in Fc Receptor Complexes
score: 4.3797216, Advances in Immunology, 2006, Daëron, Marc; Lesourne, Renaud

Negative Signaling in Fc Receptor Complexes
score: 4.3797216, Advances in Immunology, 2006, Daëron, Marc; Lesourne, Renaud

Autoimmunity and Apoptosis
score: 4.3767655, Immunity, 2001, Beutler, Bruce

Detecting the Unusual: Natural Killer Cells
score: 4.3766754, Progress in Nucleic Acid Research and Molecular Biology, 2006, Volz, Armin; Radeloff, Britta

Detecting the Unusual: Natural Killer Cells
score: 4.3766754, Progress in Nucleic Acid Research and Molecular Biology, 2006, Volz, Armin; Radeloff, Britta

The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains.
score: 4.3766485, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Kay, B K; Williamson, M P; Sudol, M

Sequence, Structure and Energetic Determinants of Phosphopeptide Selectivity of SH2 Domains
score: 4.3759547, Journal of Molecular Biology, 2003, Sheinerman, Felix B.; Al-Lazikani, Bissan; Honig, Barry

Downregulation of Akt activity contributes to the growth arrest induced by FGF in chondrocytes.
score: 4.3758312, Journal of cellular physiology, 2006, Priore, Riccardo; Dailey, Lisa; Basilico, Claudio

Role of caspases in the regulation of apoptotic pancreatic islet beta-cells death.
score: 4.3745813, Journal of cellular physiology, 2004, Hui, Hongxiang et. al.

Monoubiquitinylation Regulates Endosomal Localization of Lst2, a Negative Regulator of EGF Receptor Signaling
score: 4.3743013, Developmental Cell, 2009, Mosesson, Yaron et. al.

Defining SH2 domain and PTP specificity by screening combinatorial peptide libraries
score: 4.3733612, Methods, 2007, Wavreille, Anne-Sophie et. al.

HIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanisms
score: 4.3730945, Molecular Aspects of Medicine, 2010, Andrew, Amy; Strebel, Klaus

Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation
score: 4.3716937, Cell, 2008, Duda, David M. et. al.

Cancer Cell‐Based Genomic and Small Molecule Screens
score: 4.37054, Advances in Cancer Research, 2006, Caldwell, Jeremy S.

Cancer Cell‐Based Genomic and Small Molecule Screens
score: 4.37054, Advances in Cancer Research, 2006, Caldwell, Jeremy S.

Electrostatic interactions in the reconstitution of an SH2 domain from constituent peptide fragments.
score: 4.3694851, Protein science : a publication of the Protein Society, 2003, Ojennus, Deanna Dahlke; Lehto, Sarah E; Wuttke, Deborah S

The type I interferon signaling pathway is a target for glucocorticoid inhibition.
score: 4.3683976, Molecular and cellular biology, 2010, Flammer, Jamie R et. al.

Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding.
score: 4.3677153, Journal of cell science, 1999, Schlöndorff, J; Blobel, C P

NEMO oligomerization in the dynamic assembly of the IkappaB kinase core complex.
score: 4.367081, The FEBS journal, 2007, Fontan, Elisabeth et. al.

Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling.
score: 4.366344, Molecular and cellular biology, 2010, Ritt, Daniel A et. al.

Leukocyte Migration and Adhesion
score: 4.3655948, Advances in Immunology, 1995, Imhof, Beat A.; Dunon, Dominique

Leukocyte Migration and Adhesion
score: 4.3655948, Advances in Immunology, 1995, Imhof, Beat A.; Dunon, Dominique

Adhesion molecule signalling: not always a sticky business.
score: 4.3629667, Nature reviews. Molecular cell biology, 2011, Cavallaro, Ugo; Dejana, Elisabetta

Control of motile and invasive cell phenotypes by focal adhesion kinase
score: 4.3624407, BBA - Molecular Cell Research, 2004, Schlaepfer, David D; Mitra, Satyajit K; Ilic, Dusko

Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b.
score: 4.3619105, Journal of virology, 2000, Hofmann, H; Flöss, S; Stamminger, T

The SH4-Unique-SH3-SH2 domains dictate specificity in signaling that differentiate c-Yes from c-Src.
score: 4.3618296, Journal of cell science, 2003, Summy, Justin M et. al.

Evolution of effectors and receptors of innate immunity
score: 4.3605808, Developmental and Comparative Immunology, 2001, Magor, Brad G.; Magor, Kathy E.

Epidermal growth factor receptor: mechanisms of activation and signalling
score: 4.3602948, Experimental Cell Research, 2003, Jorissen, Robert N et. al.

Identification of the putative mammalian orthologue of Sec31P, a component of the COPII coat.
score: 4.3602006, Journal of cell science, 1999, Shugrue, C A et. al.

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood.
score: 4.3600142, Proceedings of the National Academy of Sciences of the United States of America, 1999, Brown, M S; Goldstein, J L

Ubiquitination and endocytosis of the high affinity receptor for IgE
score: 4.3486565, Molecular Immunology, 2010, Molfetta, Rosa et. al.

The Hsp90 chaperone machinery: Conformational dynamics and regulation by co-chaperones
score: 4.3475194, BBA - Molecular Cell Research, 2012, Li, Jing; Soroka, Joanna; Buchner, Johannes

IκB kinase β (IKKβ/IKK2/IKBKB)—A key molecule in signaling to the transcription factor NF-κB
score: 4.3467453, Cytokine and Growth Factor Reviews, 2008, Schmid, Johannes A.; Birbach, Andreas

A Signal Peptide Derived from hsp60 Binds HLA-E and Interferes with CD94/NKG2A Recognition
score: 4.3447365, The Journal of Experimental Medicine, 2002, Michaëlsson, Jakob et. al.

Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: Mechanistic insights
score: 4.3363196, Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2009, Thompson, Larry H.; Hinz, John M.

Insulin regulates alveolar epithelial function by inducing Na+/K+-ATPase translocation to the plasma membrane in a process mediated by the action of Akt.
score: 4.3340085, Journal of cell science, 2010, Comellas, Alejandro P et. al.

Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis.
score: 4.3326549, Proceedings of the National Academy of Sciences of the United States of America, 2002, Gent, Jürgen et. al.

The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands.
score: 4.3291268, Development (Cambridge, England), 1996, Sun, X; Artavanis-Tsakonas, S

Synapse associated protein 102 is a novel binding partner to the cytoplasmic terminus of neurone-glial related cell adhesion molecule.
score: 4.3230644, Journal of neurochemistry, 2005, Davey, Fleur et. al.

Nervous Wreck, an SH3 Adaptor Protein that Interacts with Wsp, Regulates Synaptic Growth in Drosophila
score: 4.3219464, Neuron, 2004, Coyle, Ian P et. al.

The Membrane Transport Factor TAP/p115 Cycles between the Golgi and Earlier Secretory Compartments and Contains Distinct Domains Required for Its Localization and Function
score: 4.3207196, The Journal of Cell Biology, 1998, Nelson, David S. et. al.

Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo
score: 4.3205382, The Journal of Experimental Medicine, 2008, Bezman, Natalie A. et. al.

The multifaceted roles of glycogen synthase kinase 3β in cellular signaling
score: 4.318848, Progress in Neurobiology, 2001, Grimes, Carol A; Jope, Richard S

Ad hoc reviewers
score: 4.3179773, Journal of immunology (Baltimore, Md. : 1950), 2000,

Association Between HLA-DM and HLA-DR In Vivo
score: 4.3172062, Immunity, 1996, Sanderson, Frances et. al.

Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag).
score: 4.3161802, Proceedings of the National Academy of Sciences of the United States of America, 2001, VerPlank, L et. al.

The molecular logic of Notch signaling--a structural and biochemical perspective.
score: 4.3156794, Journal of cell science, 2008, Gordon, Wendy R; Arnett, Kelly L; Blacklow, Stephen C

NLRC5: a newly discovered MHC class I transactivator (CITA)
score: 4.3145748, Microbes and Infection, 2012, Meissner, Torsten B.; Li, Amy; Kobayashi, Koichi S.

A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling.
score: 4.3140805, Nature biotechnology, 2003, Blagoev, Blagoy et. al.

Regulation of MHC class II signal transduction by the B cell coreceptors CD19 and CD22.
score: 4.3138242, Journal of immunology (Baltimore, Md. : 1950), 2000, Bobbitt, K R; Justement, L B

TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer.
score: 4.3135909, Immunological reviews, 2011, Walczak, Henning

Carcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulators.
score: 4.3135739, Oncogene, 2002, Conte, Nathalie et. al.

Threonine phosphorylation sites in the beta 2 and beta 7 leukocyte integrin polypeptides.
score: 4.3133849, Journal of immunology (Baltimore, Md. : 1950), 2003, Hilden, Tiina J et. al.

Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway.
score: 4.3106365, Molecular and cellular biology, 2008, Varghese, Bentley et. al.

The Phosphotyrosine Phosphatase SHP-2 Participates in a Multimeric Signaling Complex and Regulates T Cell Receptor (TCR) coupling to the Ras/Mitogen-activated Protein Kinase (MAPK) Pathway in Jurkat T Cells
score: 4.3097431, The Journal of Experimental Medicine, 1998, Frearson, Julie A.; Alexander, Denis R.

Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells.
score: 4.3097154, Cancer research, 2001, Hauck, C R et. al.

Interactions of NK cell receptor KIR3DL1*004 with chaperones and conformation-specific antibody reveal a functional folded state as well as predominant intracellular retention.
score: 4.3092664, Journal of immunology (Baltimore, Md. : 1950), 2011, Taner, Sabrina B et. al.

RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas.
score: 4.3091004, Cancer research, 2007, Fagiani, Ernesta et. al.

Phosphoinositide 3-kinase in disease: timing, location, and scaffolding
score: 4.3087504, Current Opinion in Cell Biology, 2005, Wymann, Matthias P; Marone, Romina

A Functional Requirement for PAK1 Binding to the KH(2) Domain of the Fragile X Protein-Related FXR1
score: 4.3066763, Molecular Cell, 2010, Say, Evonne et. al.

Activation of Interferon Regulatory Factor 5 by Site Specific Phosphorylation
score: 4.3057148, PLoS ONE, 2012, Chang Foreman, Hui-Chen et. al.

Genome wide analysis of human genes transcriptionally and post-transcriptionally regulated by the HTLV-I protein p30
score: 4.3034861, BMC Genomics, 2009, Taylor, John M; Ghorbel, Sofiane; Nicot, Christophe

Post-transcriptional processes
score: 4.3026497, Current Opinion in Cell Biology, 1993,

Human IL-1 beta processing and secretion in recombinant baculovirus-infected Sf9 cells is blocked by the cowpox virus serpin crmA.
score: 4.2983246, Journal of immunology (Baltimore, Md. : 1950), 1995, Howard, A D et. al.

Hsp90 inhibition transiently activates Src kinase and promotes Src-dependent Akt and Erk activation.
score: 4.2982841, Proceedings of the National Academy of Sciences of the United States of America, 2006, Koga, Fumitaka et. al.

Mechanisms of brain injury: L1 cell adhesion molecule as a target for ethanol-induced prenatal brain injury
score: 4.2975565, Seminars in Pediatric Neurology, 2001, Bearer, Cynthia F.

In vitro treatment of human monocytes/macrophages with myristoylated recombinant Nef of human immunodeficiency virus type 1 leads to the activation of mitogen-activated protein kinases, IkappaB kinases, and interferon regulatory factor 3 and to the release of beta interferon.
score: 4.2962185, Journal of virology, 2007, Mangino, Giorgio et. al.

Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through α2β1 integrin
score: 4.2954786, The Journal of Cell Biology, 2004, Bix, Gregory et. al.

Regulating the Regulators: Control of Protein Ubiquitination and Ubiquitin-like Modifications by Extracellular Stimuli
score: 4.2937907, Molecular Cell, 2005, Gao, Min; Karin, Michael

PTEN Negatively Regulates Engulfment of Apoptotic Cells by Modulating Activation of Rac GTPase.
score: 4.2909302, Journal of immunology (Baltimore, Md. : 1950), 2011, Mondal, Subhanjan et. al.

v-Src induces Shc binding to tyrosine 63 in the cytoplasmic domain of the LDL receptor-related protein 1.
score: 4.286721, Oncogene, 2003, Barnes, Helen; Ackermann, Elizabeth J; van der Geer, Peter

The Interleukin‐1 Receptor Family
score: 4.2851503, Vitamins and Hormones, 2006, Boraschi, Diana; Tagliabue, Aldo

The Interleukin‐1 Receptor Family
score: 4.2851503, Vitamins and Hormones, 2006, Boraschi, Diana; Tagliabue, Aldo

Ack1 Mediated AKT/PKB Tyrosine 176 Phosphorylation Regulates Its Activation
score: 4.2840363, PLoS ONE, 2010, Mahajan, Kiran et. al.

p56(dok-2) as a cytokine-inducible inhibitor of cell proliferation and signal transduction.
score: 4.2816089, The EMBO journal, 2000, Suzu, S et. al.

Sprouty4 negatively regulates protein kinase C activation by inhibiting phosphatidylinositol 4,5-biphosphate hydrolysis.
score: 4.2813328, Oncogene, 2009, Ayada, T et. al.

Hypoxia-inducible factor-1 (HIF-1).
score: 4.2806557, Molecular pharmacology, 2006, Ke, Qingdong; Costa, Max

Interaction of SLP adaptors with the SH2 domain of Tec family kinases.
score: 4.2806176, European journal of immunology, 1999, Su, Y W et. al.

Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors.
score: 4.2791464, EMBO reports, 2007, Sandilands, Emma et. al.

Hem-1 Complexes Are Essential for Rac Activation, Actin Polymerization, and Myosin Regulation during Neutrophil Chemotaxis
score: 4.2770342, PLoS Biology, 2006, Weiner, Orion D et. al.

Calcium Release at Fertilization in Starfish Eggs Is Mediated by Phospholipase Cγ
score: 4.2768059, The Journal of Cell Biology, 1997, Carroll, David J. et. al.

ER to Golgi Transport
score: 4.2763764, The Journal of Cell Biology, 1999, Alvarez, Cecilia et. al.

Residues phosphorylated by TFIIH are required for E2F-1 degradation during S-phase.
score: 4.2757166, The EMBO journal, 1999, Vandel, L; Kouzarides, T

Role of Lbc RhoGEF in Gα12/13-induced signals to Rho GTPase
score: 4.2748708, Cellular Signalling, 2004, Dutt, Parmesh; Nguyen, Nhan; Toksoz, Deniz

MHC II and the endocytic pathway: regulation by invariant chain.
score: 4.272571, Scandinavian journal of immunology, 2009, Landsverk, O J B; Bakke, O; Gregers, T F

Active recycling of yeast Golgi mannosyltransferase complexes through the endoplasmic reticulum.
score: 4.2721901, Proceedings of the National Academy of Sciences of the United States of America, 2000, Todorow, Z; Spang, A; Carmack, E; Yates, J; Schekman, R

Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential.
score: 4.2721556, Oncogene, 2004, Chikumi, Hiroki et. al.

Protein kinase C-ζ phosphorylates insulin-responsive aminopeptidase in vitro at Ser-80 and Ser-91
score: 4.2710764, Archives of Biochemistry and Biophysics, 2002, Ryu, Jiwon et. al.

Compartmentalization of B-cell antigen receptor functions
score: 4.2707818, Molecular Immunology, 1996, Lankester, Arjan C.; Van Lier, RenéA.W.

Signal Transduction through MAP Kinase Cascades
score: 4.2705832, Advances in Cancer Research, 1998, Lewis, Timothy S.; Shapiro, Paul S.; Ahn, Natalie G.

Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin
score: 4.2702119, Nucleic Acids Research, 2011, Sandler, Heike et. al.

Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases
score: 4.2684982, FEBS Letters, 2001, Waterman, Hadassa; Yarden, Yosef

The RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradation
score: 4.2661443, The EMBO Journal, 2012, Cano, Florencia et. al.

The language of SH2 domain interactions defines phosphotyrosine-mediated signal transduction
score: 4.2649614, FEBS Letters, 2012, Liu, Bernard A.; Engelmann, Brett W.; Nash, Piers D.

The language of SH2 domain interactions defines phosphotyrosine-mediated signal transduction
score: 4.2649614, FEBS Letters, 2012, Liu, Bernard A.; Engelmann, Brett W.; Nash, Piers D.

The language of SH2 domain interactions defines phosphotyrosine-mediated signal transduction
score: 4.2649614, FEBS Letters, 2012, Liu, Bernard A.; Engelmann, Brett W.; Nash, Piers D.

Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins
score: 4.2630592, BBA - Reviews on Biomembranes, 1999, Buday, László

Poly(C)-binding protein 1 (PCBP1) mediates housekeeping degradation of mitochondrial antiviral signaling (MAVS).
score: 4.2587902, Cell research, 2012, Zhou, Xiang; You, Fuping; Chen, Huihui; Jiang, Zhengfan

Human immunodeficiency virus type 1 Vpr-mediated G(2) cell cycle arrest: Vpr interferes with cell cycle signaling cascades by interacting with the B subunit of serine/threonine protein phosphatase 2A.
score: 4.258199, The EMBO journal, 2000, Hrimech, M; Yao, X J; Branton, P E; Cohen, E A

Cell differentiation
score: 4.257514, Current Opinion in Cell Biology, 1997,

Assembly and retention of CD1b heavy chains in the endoplasmic reticulum.
score: 4.2563385, Journal of immunology (Baltimore, Md. : 1950), 1997, Sugita, M; Porcelli, S A; Brenner, M B

Ubiquitination of α5β1 Integrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-Integrin Complexes
score: 4.2559065, Developmental Cell, 2010, Lobert, Viola Hélène et. al.

Ubiquitination of α5β1 Integrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-Integrin Complexes
score: 4.2559065, Developmental Cell, 2010, Lobert, Viola Hélène et. al.

EphA Receptors Regulate Growth Cone Dynamics through the Novel Guanine Nucleotide Exchange Factor Ephexin
score: 4.2536517, Cell, 2001, Shamah, Steven M. et. al.

FGF receptors ubiquitylation: dependence on tyrosine kinase activity and role in downregulation
score: 4.2530695, FEBS Letters, 2002, Monsonego-Ornan, E; Adar, R; Rom, E; Yayon, A

The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity.
score: 4.250689, Molecular and cellular biology, 2007, García-Mata, Rafael et. al.

Developmental biology of the pancreas: A comprehensive review
score: 4.2500082, Developmental Biology, 2009, Gittes, George K.

Inhibitors of signal transduction protein kinases as targets for cancer therapy
score: 4.2482314, Biotechnology Annual Review, 2006, Mikalsen, Theresa; Gerits, Nancy; Moens, Ugo

Inhibitors of signal transduction protein kinases as targets for cancer therapy
score: 4.2482314, Biotechnology Annual Review, 2006, Mikalsen, Theresa; Gerits, Nancy; Moens, Ugo

Membrane permeability
score: 4.2457388, Current Opinion in Cell Biology, 1992,

The Language of SH2 Domain Interactions Defines Phosphotyrosine-Mediated Signal Transduction
score: 4.2452053, FEBS Letters, 2012, Liu, Bernard A.; Engelmann, Brett W.; Nash, Piers D.

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling.
score: 4.2447958, The EMBO journal, 1997, Graus-Porta, D; Beerli, R R; Daly, J M; Hynes, N E

Neural cell adhesion molecule regulates the cellular response to fibroblast growth factor.
score: 4.2433166, Journal of cell science, 2007, Francavilla, Chiara et. al.

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2.
score: 4.2426971, The EMBO journal, 1997, Waskiewicz, A J; Flynn, A; Proud, C G; Cooper, J A

The cell cycle is a redox cycle: Linking phase-specific targets to cell fate
score: 4.2415689, Free Radical Biology and Medicine, 2009, Burhans, William C.; Heintz, Nicholas H.

Expression of a Dominant Negative FGF Receptor Inhibits Axonal Growth and FGF Receptor Phosphorylation Stimulated by CAMs
score: 4.2409695, Neuron, 1997, Saffell, Jane L. et. al.

HIV and HLA Class I: An Evolving Relationship
score: 4.2388643, Immunity, 2012, Goulder, Philip J.R.; Walker, Bruce D.

Fas Induces Cytoplasmic Apoptotic Responses and Activation of the MKK7-JNK/SAPK and MKK6-p38 Pathways Independent of CPP32-like Proteases
score: 4.2371436, The Journal of Cell Biology, 1997, Toyoshima, Fumiko; Moriguchi, Tetsuo; Nishida, Eisuke

UBXD7 Binds Multiple Ubiquitin Ligases and Implicates p97 in HIF1α Turnover
score: 4.236893, Cell, 2008, Alexandru, Gabriela et. al.

Cytokines in Hematopoiesis: Specificity and Redundancy in Receptor Function
score: 4.2366481, Advances in Protein Chemistry, 1998, Socolovsky, Merav et. al.

Cytokines in Hematopoiesis: Specificity and Redundancy in Receptor Function
score: 4.2366481, Advances in Protein Chemistry, 1998, Socolovsky, Merav et. al.

An Electrostatic Engine Model for Autoinhibition and Activation of the Epidermal Growth Factor Receptor (EGFR/ErbB) Family
score: 4.2366136, The Journal of General Physiology, 2005, McLaughlin, Stuart et. al.

Feedback regulation of cholesterol synthesis: sterol-accelerated ubiquitination and degradation of HMG CoA reductase.
score: 4.2332687, Cell research, 2008, DeBose-Boyd, Russell A

IgCAMs: bidirectional signals underlying neurite growth
score: 4.2328736, Current Opinion in Cell Biology, 2000, Kamiguchi, Hiroyuki; Lemmon, Vance

Structure-Activity Relationships of G Protein-Coupled Receptors
score: 4.2326507, Archives of Medical Research, 1999, Ulloa-Aguirre, Alfredo et. al.

MicroRNAs and Toll-like Receptor/Interleukin-1 Receptor Signaling
score: 4.2314956, Journal of Hematology & Oncology, 2012, Virtue, Anthony; Wang, Hong; Yang, Xiao-feng

Activation of the Small GTP-binding Protein Ras in the Heart by Hypertrophic Agonists
score: 4.230665, Trends in Cardiovascular Medicine, 2000, Sugden, Peter H; Clerk, Angela

SH2 and PTB domain interactions in tyrosine kinase signal transduction
score: 4.2303628, Current Opinion in Chemical Biology, 1997, Shoelson, Steven E

RalB GTPase-Mediated Activation of the IκB Family Kinase TBK1 Couples Innate Immune Signaling to Tumor Cell Survival
score: 4.2286039, Cell, 2006, Chien, Yuchen et. al.

Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix.
score: 4.223393, Molecular and cellular biology, 2009, Kalinina, Juliya et. al.

Endosome maturation.
score: 4.2232497, The EMBO journal, 2011, Huotari, Jatta; Helenius, Ari

Biochemical characterization of Cdk2-Speedy/Ringo A2
score: 4.2230805, BMC Biochemistry, 2005, Cheng, Aiyang et. al.

Aspartyl-(asparaginyl)-β-hydroxylase regulates hepatocellular carcinoma invasiveness
score: 4.222278, Journal of Hepatology, 2006, Monte, Suzanne M. de la et. al.

Activation of the erythropoietin receptor by the gp55-P viral envelope protein is determined by a single amino acid in its transmembrane domain.
score: 4.2173409, The EMBO journal, 1999, Constantinescu, S N et. al.

Glycosaminoglycans: key players in cancer cell biology and treatment.
score: 4.2164969, The FEBS journal, 2012, Afratis, Nikos et. al.

A secretion inhibitory signal transduction molecule on mast cells is another C-type lectin.
score: 4.2148652, Proceedings of the National Academy of Sciences of the United States of America, 1995, Guthmann, M D; Tal, M; Pecht, I

Protein kinase WNK3 increases cell survival in a caspase-3-dependent pathway.
score: 4.2148043, Oncogene, 2006, Veríssimo, F; Silva, E; Morris, J D; Pepperkok, R; Jordan, P

Identification of a novel EGF-sensitive cell cycle checkpoint
score: 4.2130182, Experimental Cell Research, 2007, Walker, Francesca; Zhang, Hui-Hua; Burgess, Antony W.

Mammary Epithelial Cell-Cycle Progression via the α 2β 1 Integrin
score: 4.2121498, The American Journal of Pathology, 2001, Klekotka, Paul A. et. al.

Structure and biological interactions of heparin and heparan sulfate
score: 4.2108841, Advances in Carbohydrate Chemistry and Biochemistry, 2001, Casu, Benito; Lindahl, Ulf

Structure and biological interactions of heparin and heparan sulfate
score: 4.2108841, Advances in Carbohydrate Chemistry and Biochemistry, 2001, Casu, Benito; Lindahl, Ulf

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells
score: 4.2108344, Immunity, 1995, Stüber, Eckhard et. al.

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells
score: 4.2108344, Immunity, 1995, Stüber, Eckhard et. al.

Treslin Collaborates with TopBP1 in Triggering the Initiation of DNA Replication
score: 4.2104409, Cell, 2010, Kumagai, Akiko et. al.

Signaling by the cytokine receptor superfamily just another kinase story
score: 4.2094386, Trends in Endocrinology & Metabolism, 1994, Ihle, James N.

BDCA2/FcɛRIγ Complex Signals through a Novel BCR-Like Pathway in Human Plasmacytoid Dendritic Cells
score: 4.2090832, PLoS Biology, 2007, Cao, Wei et. al.

Signaling and ligand interaction of ILT7: receptor-mediated regulatory mechanisms for plasmacytoid dendritic cells.
score: 4.2083731, Immunological reviews, 2010, Cao, Wei; Bover, Laura

Molecular chaperones and the stress of oncogenesis.
score: 4.2077184, Oncogene, 2004, Mosser, Dick D; Morimoto, Richard I

IL-2, but not IL-4 and other cytokines, induces phosphorylation of a 98-kDa protein associated with SHP-2, phosphatidylinositol 3'-kinase, and Grb2.
score: 4.2068977, Journal of immunology (Baltimore, Md. : 1950), 1999, Gadina, M; Sudarshan, C; O'Shea, J J

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex.
score: 4.2065049, Proceedings of the National Academy of Sciences of the United States of America, 2000, Gmachl, M et. al.

Functions and regulations of fibroblast growth factor signaling during embryonic development
score: 4.2051168, Developmental Biology, 2005, Thisse, Bernard; Thisse, Christine

Small interfering RNA-mediated knockdown of notch ligands in primary CD4+ T cells and dendritic cells enhances cytokine production.
score: 4.2039176, Journal of immunology (Baltimore, Md. : 1950), 2006, Stallwood, Yvette et. al.

Human Proline-Rich Nuclear Receptor Coregulatory Protein 2 Mediates an Interaction between mRNA Surveillance Machinery and Decapping Complex
score: 4.2035086, Molecular Cell, 2009, Cho, Hana; Kim, Kyoung Mi; Kim, Yoon Ki

A Bony Fish Immunological Receptor of the NITR Multigene Family Mediates Allogeneic Recognition
score: 4.2027422, Immunity, 2008, Cannon, John P. et. al.

Innate immune response to viral infection
score: 4.2022539, Cytokine, 2008, Koyama, Shohei; Ishii, Ken J.; Coban, Cevayir; Akira, Shizuo

Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts.
score: 4.2011351, Molecular and cellular biology, 1997, Tang, Y et. al.

Additive Effects of PDGF Receptor β Signaling Pathways in Vascular Smooth Muscle Cell Development
score: 4.201028, PLoS Biology, 2003, Tallquist, Michelle D; French, Wendy J; Soriano, Philippe

Interchangeable alpha chain cytoplasmic domains play a positive role in control of cell adhesion mediated by VLA-4, a beta 1 integrin
score: 4.2002468, The Journal of Experimental Medicine, 1993,

Disruption of oligomerization induces nucleocytoplasmic shuttling of leukemia-associated rho Guanine-nucleotide exchange factor.
score: 4.200225, Molecular pharmacology, 2007, Grabocka, Elda; Wedegaertner, Philip B

Pathogen recognition by innate immunity and its signaling
score: 4.2001777, Proceedings of the Japan Academy. Series B, Physical and Biological Sciences, 2009, Akira, Shizuo

Src transduces erythropoietin-induced differentiation signals through phosphatidylinositol 3-kinase.
score: 4.1982631, The EMBO journal, 2001, Kubota, Y et. al.

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis
score: 4.191984, Current Biology, 1998, Roche, Serge et. al.

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis
score: 4.191984, Current Biology, 1998, Roche, Serge et. al.

Bibliography of biomedical ultrasound
score: 4.1915777, Ultrasound in Medicine & Biology, 1990, White, Denis; White, Elizabeth

Endogenous Opiates and Behavior: 2011
score: 4.1915478, Peptides, 2012, Bodnar, Richard J.

EBI1/CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation.
score: 4.1912584, Journal of immunology (Baltimore, Md. : 1950), 1998, Yanagihara, S et. al.

Ras proteins: different signals from different locations.
score: 4.1899115, Nature reviews. Molecular cell biology, 2003, Hancock, John F

GPCR mediated regulation of synaptic transmission
score: 4.1882878, Progress in Neurobiology, 2012, Betke, Katherine M.; Wells, Christopher A.; Hamm, Heidi E.

GPCR mediated regulation of synaptic transmission
score: 4.1882878, Progress in Neurobiology, 2012, Betke, Katherine M.; Wells, Christopher A.; Hamm, Heidi E.

Recruitment of Protein Phosphatase 1 to the Nuclear Envelope by a-Kinase Anchoring Protein Akap149 Is a Prerequisite for Nuclear Lamina Assembly
score: 4.188241, The Journal of Cell Biology, 2000, Steen, Rikke L. et. al.

Low-molecular-weight protein tyrosine phosphatase is a positive component of the fibroblast growth factor receptor signaling pathway.
score: 4.1874526, Molecular and cellular biology, 2002, Park, Eui Kyun et. al.

Ubiquitin sorts proteins into the intralumenal degradative compartment of the late-endosome/vacuole.
score: 4.1855652, Traffic (Copenhagen, Denmark), 2001, Urbanowski, J L; Piper, R C

TNF ligands and receptors--a matter of life and death.
score: 4.1844926, British journal of pharmacology, 2002, MacEwan, David J

The Mammalian Golgi Regulates Numb Signaling in Asymmetric Cell Division by Releasing ACBD3 during Mitosis
score: 4.183944, Cell, 2007, Zhou, Yan et. al.

The Cbl RING finger C-terminal flank controls epidermal growth factor receptor fate downstream of receptor ubiquitination
score: 4.1827955, Experimental Cell Research, 2005, Visser, Gina D.; Lill, Nancy L.

Natural killer cell receptors for major histocompatibility complex class I and related molecules in cytomegalovirus infection.
score: 4.1824756, Tissue antigens, 2004, López-Botet, M; Angulo, A; Gumá, M

IL-1beta-induced phosphorylation of PKB/Akt depends on the presence of IRAK-1.
score: 4.1817677, European journal of immunology, 2002, Neumann, Detlef et. al.

A role for fibronectin-leucine-rich transmembrane cell-surface proteins in homotypic cell adhesion.
score: 4.180853, EMBO reports, 2006, Karaulanov, Emil E; Böttcher, Ralph T; Niehrs, Christof

A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction.
score: 4.1804783, Molecular and cellular biology, 1992, Muller, A J et. al.

The G protein-coupled receptor kinase-2 is a TGFbeta-inducible antagonist of TGFbeta signal transduction.
score: 4.1796206, The EMBO journal, 2005, Ho, Joanne et. al.

Modulation of host immune responses by clinically relevant human DNA and RNA viruses
score: 4.1790613, Current Opinion in Microbiology, 2000, Brander, Christian; Walker, Bruce D

The Mechanisms of Vesicle Budding and Fusion
score: 4.1780212, Cell, 2004, Bonifacino, Juan S; Glick, Benjamin S

Chapter 6 Cell and Molecular Biology of the Novel Protein Tyrosine‐Phosphatase‐Interacting Protein 51 1
score: 4.1779918, International Review of Cell and Molecular Biology, 2009, Stenzinger, Albrecht et. al.

Chapter 6 Cell and Molecular Biology of the Novel Protein Tyrosine‐Phosphatase‐Interacting Protein 511
score: 4.1779918, International Review of Cell and Molecular Biology, 2009, Stenzinger, Albrecht et. al.

Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling
score: 4.1767792, The Journal of Cell Biology, 2007, Strochlic, Todd I. et. al.

Adaptors and linkers in T and B cells
score: 4.1762289, Current Opinion in Immunology, 2004, Simeoni, Luca et. al.

Regulation of CDK4
score: 4.1742947, Cell Division, 2006, Bockstaele, Laurence et. al.

IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK).
score: 4.173718, Proceedings of the National Academy of Sciences of the United States of America, 2001, Li, X; Commane, M; Jiang, Z; Stark, G R

Trafficking of receptor tyrosine kinases to the nucleus
score: 4.1729634, Experimental Cell Research, 2009, Carpenter, Graham; Liao, Hong-Jun

A Two Decade Contribution of Molecular Cell Biology to the Centennial of Alzheimer's Disease: Are We Progressing Toward Therapy?
score: 4.1728026, International Review of Cytology, 2006, Dillen, Katleen; Annaert, Wim

A Two Decade Contribution of Molecular Cell Biology to the Centennial of Alzheimer's Disease: Are We Progressing Toward Therapy?
score: 4.1728026, International Review of Cytology, 2006, Dillen, Katleen; Annaert, Wim

Why is delta endocytosis required for effective activation of notch?
score: 4.1723142, Developmental dynamics : an official publication of the American Association of Anatomists, 2006, Chitnis, Ajay

New Insights into Nucleolar Architecture and Activity
score: 4.172262, International Review of Cytology, 2006, Raška, Ivan; Shaw, Peter J.; Cmarko, Dušan

New Insights into Nucleolar Architecture and Activity
score: 4.172262, International Review of Cytology, 2006, Raška, Ivan; Shaw, Peter J.; Cmarko, Dušan

Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
score: 4.171558, Molecular Cell, 2000, Dhalluin, Christophe et. al.

The molecular role of Myc in growth and transformation: recent discoveries lead to new insights.
score: 4.171517, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Facchini, L M; Penn, L Z

TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis.
score: 4.1702733, Journal of leukocyte biology, 2008, Ashtekar, Amit R et. al.

Signal Transduction through MAP Kinase Cascades
score: 4.1667163, Advances in Cancer Research, 1998, Lewis, Timothy S.; Shapiro, Paul S.; Ahn, Natalie G.

Membrane IgM-induced tyrosine phosphorylation of CD19 requires a CD19 domain that mediates association with components of the B cell antigen receptor complex.
score: 4.1655292, Journal of immunology (Baltimore, Md. : 1950), 1997, Carter, R H; Doody, G M; Bolen, J B; Fearon, D T

Pattern recognition receptors: a contemporary view on liver diseases.
score: 4.1643145, Hepatology (Baltimore, Md.), 2006, Szabo, Gyongyi; Dolganiuc, Angela; Mandrekar, Pranoti

Molecular mechanisms of death-receptor-mediated apoptosis.
score: 4.1629653, Chembiochem : a European journal of chemical biology, 2001, Sartorius, U; Schmitz, I; Krammer, P H

c-Cbl ubiquitinates the EGF receptor at the plasma membrane and remains receptor associated throughout the endocytic route.
score: 4.1621515, Journal of cell science, 2001, de Melker, A A et. al.

Integrin-Specific Activation of Rac Controls Progression through the G 1 Phase of the Cell Cycle
score: 4.159394, Molecular Cell, 2001, Mettouchi, Amel et. al.

The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression
score: 4.1584946, Pharmacology and Therapeutics, 2007, Kim, Sang K.; Novak, Raymond F.

Surface NK receptors and their ligands on tumor cells
score: 4.1574593, Seminars in Immunology, 2006, Moretta, Lorenzo et. al.

Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells.
score: 4.1573103, Molecular and cellular biology, 2005, Parsons, Maddy et. al.

A Dimeric Kinase Assembly Underlying Autophosphorylation in the p21 Activated Kinases
score: 4.1568971, Journal of Molecular Biology, 2006, Pirruccello, Michelle et. al.

Regulating Vav1 phosphorylation by the SHP-1 tyrosine phosphatase is a fine-tuning mechanism for the negative regulation of DISC formation and Fas-mediated cell death signaling.
score: 4.1557789, Cell death and differentiation, 2008, Koncz, G; Kerekes, K; Chakrabandhu, K; Hueber, A-O

Activation of ternary complex factor Elk-1 by stress-activated protein kinases
score: 4.1540249, Current Biology, 1995, Gille, Hendrik; Strahl, Thomas; Shaw, Peter E.

Immunoreceptor tyrosine-based inhibition motif-bearing receptors regulate the immunoreceptor tyrosine-based activation motif-induced activation of immune competent cells
score: 4.1539777, Immunology Letters, 1999, Gergely, János; Pecht, Israel; Sármay, Gabriella

LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy.
score: 4.1520366, Molecular and cellular biology, 2007, Shattuck, David L et. al.

OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress.
score: 4.1517396, Molecular and cellular biology, 2010, Wehner, Karen A; Schütz, Sylvia; Sarnow, Peter

AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter.
score: 4.1504388, Cancer research, 2003, Cai, Dongpo et. al.

The p75 neurotrophin receptor: multiple interactors and numerous functions
score: 4.1502659, Progress in Brain Research, 2004, Gentry, Jennifer J.; Barker, Philip A.; Carter, Bruce D.

The p75 neurotrophin receptor: multiple interactors and numerous functions
score: 4.1502659, Progress in Brain Research, 2004, Gentry, Jennifer J.; Barker, Philip A.; Carter, Bruce D.

TAO kinases mediate activation of p38 in response to DNA damage.
score: 4.1496694, The EMBO journal, 2007, Raman, Malavika et. al.

Tyrosine phosphorylation of Shc is not required for proliferation or viability signaling by granulocyte-macrophage colony-stimulating factor in hematopoietic cell lines.
score: 4.1495192, Journal of immunology (Baltimore, Md. : 1950), 1996, Durstin, M; Inhorn, R C; Griffin, J D

The human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation technique
score: 4.1470079, Nucleic Acids Research, 2010, Totaro, Antonio et. al.

Molecular and Cellular Aspects of X-Linked Agammaglobulinemia
score: 4.1459992, Advances in Immunology, 1995, Sideras, Paschalis; Smith, C.I. Edvard

Molecular and Cellular Aspects of X-Linked Agammaglobulinemia
score: 4.1459992, Advances in Immunology, 1995, Sideras, Paschalis; Smith, C.I. Edvard

Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis.
score: 4.1454964, Molecular and cellular biology, 2009, Xie, Zhonglin et. al.

Integrin-Mediated Cell-Matrix Interaction in Physiological and Pathological Blood Vessel Formation
score: 4.1449783, Journal of Oncology, 2011, Niland, Stephan; Eble, Johannes A.

The Skap-hom Dimerization and PH Domains Comprise a 3′-Phosphoinositide-Gated Molecular Switch
score: 4.1418718, Molecular Cell, 2008, Swanson, Kenneth D. et. al.

Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage.
score: 4.1417106, Journal of virology, 2006, Lin, Rongtuan et. al.

In vivo and in vitro modulation of HLA-DM and HLA-DO is induced by B lymphocyte activation.
score: 4.1384343, Journal of immunology (Baltimore, Md. : 1950), 2001, Roucard, C et. al.

Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis.
score: 4.1380674, Molecular and cellular biology, 1997, Lenczowski, J M et. al.

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b.
score: 4.1378329, The EMBO journal, 2006, Buchwald, Gretel et. al.

The PDGF receptor phosphorylates Tyr 138 in the c-Src SH3 domain in vivo reducing peptide ligand binding.
score: 4.1375335, Oncogene, 1997, Broome, M A; Hunter, T

The Bcl10–Malt1 complex segregates FcɛRI-mediated nuclear factor κB activation and cytokine production from mast cell degranulation
score: 4.1375126, The Journal of Experimental Medicine, 2006, Klemm, Stefanie et. al.

Bcl10 controls TCR- and FcgammaR-induced actin polymerization.
score: 4.1372975, Journal of immunology (Baltimore, Md. : 1950), 2007, Rueda, Daniel et. al.

Switch from αvβ5 to αvβ6 integrin expression protects squamous cell carcinomas from anoikis
score: 4.136453, The Journal of Cell Biology, 2004, Janes, Sam M.; Watt, Fiona M.

Differential functions of the two Src homology 2 domains in protein tyrosine phosphatase SH-PTP1.
score: 4.1350281, Proceedings of the National Academy of Sciences of the United States of America, 1996, Pei, D; Wang, J; Walsh, C T

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.
score: 4.1345437, Molecular and cellular biology, 1994, Songyang, Z et. al.

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein.
score: 4.1322478, Molecular and cellular biology, 1996, Borg, J P; Ooi, J; Levy, E; Margolis, B

SLP-76 Regulates Fcγ Receptor and Integrin Signaling in Neutrophils
score: 4.1296548, Immunity, 2003, Newbrough, Sally A et. al.

Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.
score: 4.128091, Pharmacological reviews, 2011, Kimple, Adam J et. al.

Bcl10 plays a divergent role in NK cell-mediated cytotoxicity and cytokine generation.
score: 4.1275624, Journal of immunology (Baltimore, Md. : 1950), 2007, Malarkannan, Subramaniam et. al.

Autoubiquitination of BCA2 RING E3 ligase regulates its own stability and affects cell migration.
score: 4.1269113, Molecular cancer research : MCR, 2008, Amemiya, Yutaka; Azmi, Peter; Seth, Arun

Activation of protein kinase D3 by signaling through Rac and the α subunits of the heterotrimeric G proteins G 12 and G 13
score: 4.1263889, Cellular Signalling, 2006, Yuan, Jingzhen; Rey, Osvaldo; Rozengurt, Enrique

Clathrin interaction and subcellular localization of Ce-DAB-1, an adaptor for protein secretion in Caenorhabditis elegans.
score: 4.1254901, Traffic (Copenhagen, Denmark), 2006, Kamikura, Darren M; Cooper, Jonathan A

APC16 is a conserved subunit of the anaphase-promoting complex/cyclosome.
score: 4.1253463, Journal of cell science, 2010, Kops, Geert J P L et. al.

Role of NF kappa B activator Act1 in CD40-mediated signaling in epithelial cells.
score: 4.1248447, Proceedings of the National Academy of Sciences of the United States of America, 2002, Qian, Youcun; Zhao, Zhendong; Jiang, Zhengfan; Li, Xiaoxia

Phosphorylation of CLASP2 by GSK-3beta regulates its interaction with IQGAP1, EB1 and microtubules.
score: 4.1241217, Journal of cell science, 2009, Watanabe, Takashi et. al.

Cargo recognition during clathrin-mediated endocytosis: a team effort
score: 4.1216895, Current Opinion in Cell Biology, 2004, Sorkin, Alexander

The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase.
score: 4.1214151, Proceedings of the National Academy of Sciences of the United States of America, 1992, Chang, H W; Watson, J C; Jacobs, B L

Structural insights into the molecular mechanism of calcium-dependent vesicle–membrane fusion
score: 4.1199268, Current Opinion in Structural Biology, 2001, Brunger, Axel T

mTOR and S6K1 Mediate Assembly of the Translation Preinitiation Complex through Dynamic Protein Interchange and Ordered Phosphorylation Events
score: 4.1197002, Cell, 2005, Holz, Marina K. et. al.

The TFG protein, involved in oncogenic rearrangements, interacts with TANK and NEMO, two proteins involved in the NF-kappaB pathway.
score: 4.1182066, Journal of cellular physiology, 2006, Miranda, Claudia et. al.

p38 mitogen-activated protein kinase mediates the Fas-induced mitochondrial death pathway in CD8+ T cells.
score: 4.1168452, Molecular and cellular biology, 2006, Farley, Nicholas et. al.

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker
score: 4.1166616, Molecular Cell, 2007, Sapkota, Gopal et. al.

The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals.
score: 4.1162205, Nature, 2001, Cowan, C A; Henkemeyer, M

TNF receptor-associated factor-3 signaling mediates activation of p38 and Jun N-terminal kinase, cytokine secretion, and Ig production following ligation of CD40 on human B cells.
score: 4.1142357, Journal of immunology (Baltimore, Md. : 1950), 1998, Grammer, A C et. al.

CD47 is a ligand for rat macrophage membrane signal regulatory protein SIRP (OX41) and human SIRPalpha 1.
score: 4.1141004, European journal of immunology, 2000, Vernon-Wilson, E F et. al.

Phosphorylation of the Eukaryotic Translation Initiation Factor 4E-Transporter (4E-T) by c-Jun N-Terminal Kinase Promotes Stress-Dependent P-Body Assembly.
score: 4.113875, Molecular and cellular biology, 2012, Cargnello, Marie et. al.

Nuclear trafficking and functions of endocytic proteins implicated in oncogenesis.
score: 4.1135372, Traffic (Copenhagen, Denmark), 2009, Borlido, Joana; Zecchini, Vincent; Mills, Ian G

Activities of adenovirus virus-associated RNAs: purification and characterization of RNA binding proteins.
score: 4.111826, Proceedings of the National Academy of Sciences of the United States of America, 1998, Liao, H J; Kobayashi, R; Mathews, M B

MLK3 Limits Activated Gαq Signaling to Rho by Binding to p63RhoGEF
score: 4.1115066, Molecular Cell, 2008, Swenson-Fields, Katherine I. et. al.

Structure and Function of Leukocyte Chemoattractant Receptors
score: 4.1103755, Advances in Pharmacology, 1997, Ye, Richard D.; Boulay, Franc¸ois

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
score: 4.11037, Current Biology, 1997, Sells, Mary Ann et. al.

Structure of a Heterophilic Adhesion Complex between the Human CD2 and CD58 (LFA-3) Counterreceptors
score: 4.1092433, Cell, 1999, Wang, Jia-huai et. al.

Human leukocyte antigen–G1 inhibits natural killer cytotoxicity through blocking the activating signal transduction pathway and formation of activating immunologic synapse
score: 4.1059259, Human Immunology, 2008, Yu, Yanrong; Wang, Yun; Feng, Meifu

Activation of the Lck tyrosine protein kinase by hydrogen peroxide requires the phosphorylation of Tyr-394.
score: 4.1049351, Proceedings of the National Academy of Sciences of the United States of America, 1995, Hardwick, J S; Sefton, B M

Ligand stimulation of CD155α inhibits cell adhesion and enhances cell migration in fibroblasts
score: 4.104049, Biochemical and Biophysical Research Communications, 2004, Oda, Toshiyuki; Ohka, Seii; Nomoto, Akio

Deficient Peptide Loading and MHC Class II Endosomal Sorting in a Human Genetic Immunodeficiency Disease: the Chediak-Higashi Syndrome
score: 4.1039235, The Journal of Cell Biology, 1998, Faigle, Wolfgang et. al.

Viral sequence data
score: 4.101335, Virus Research, 1991,

Notch signaling: direct or what?
score: 4.1009698, Current Opinion in Genetics & Development, 1998, Weinmaster, Gerry

XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization
score: 4.1006978, Molecular Cell, 2007, Lu, Miao et. al.

Magicin associates with the Src-family kinases and is phosphorylated upon CD3 stimulation
score: 4.0989257, Biochemical and Biophysical Research Communications, 2006, Lee, Ming-Fen et. al.

FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5.
score: 4.0961379, Journal of cell science, 2006, Li, Weiquan et. al.

Distinct roles for isoforms of the catalytic subunit of class-IA PI3K in the regulation of behaviour of murine embryonic stem cells.
score: 4.0960372, Journal of cell science, 2009, Kingham, Emmajayne; Welham, Melanie

Multiple genes and factors associated with bipolar disorder converge on growth factor and stress activated kinase pathways controlling translation initiation: Implications for oligodendrocyte viability
score: 4.094103, Neurochemistry International, 2007, Carter, C.J.

Cross-talk between dendritic cells and natural killer cells in viral infection
score: 4.0939904, Molecular Immunology, 2005, Andrews, Daniel M. et. al.

Stimulatory killer Ig-like receptors modulate T cell activation through DAP12-dependent and DAP12-independent mechanisms.
score: 4.0930486, Journal of immunology (Baltimore, Md. : 1950), 2004, Snyder, Melissa R et. al.

Sprouty: how does the branch manager work?
score: 4.0911418, Journal of cell science, 2003, Guy, Graeme R et. al.

Roles for the Ubiquitin-Proteasome Pathway in Protein Quality Control and Signaling in the Retina: Implications in the Pathogenesis of Age-Related Macular Degeneration
score: 4.0911366, Molecular Aspects of Medicine, 2012, Shang, Fu; Taylor, Allen

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin
score: 4.0906096, The Journal of Cell Biology, 2001, Dyson, Jennifer M. et. al.

The Membrane-Bound Aspartyl Protease BACE1: Molecular and Functional Properties in Alzheimer’s Disease and Beyond
score: 4.0873476, Frontiers in Physiology, 2012, Dislich, Bastian; Lichtenthaler, Stefan F.

Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner.
score: 4.0863651, Cell research, 2010, Liao, Bing; Jin, Ying

Golgi Membrane Dynamics and Lipid Metabolism
score: 4.0844725, Current Biology, 2012, Bankaitis, Vytas A.; Garcia-Mata, Rafael; Mousley, Carl J.

Heat shock protein 90 regulates phosphatidylinositol 3-kinase-related protein kinase family proteins together with the RUVBL1/2 and Tel2-containing co-factor complex.
score: 4.0839826, Cancer science, 2012, Izumi, Natsuko et. al.

Nerve growth factor mediates signal transduction through trk homodimer receptors
score: 4.0837617, Neuron, 1992, Jing, Shuqian; Tapley, Peter; Barbacid, Mariano

Signal transduction by the PDGF receptors
score: 4.0825493, Progress in Growth Factor Research, 1994, Claesson-Welsh, Lena

Beta-PIX and Rac1 GTPase mediate trafficking and negative regulation of NOD2.
score: 4.0818112, Journal of immunology (Baltimore, Md. : 1950), 2008, Eitel, Julia et. al.

Structure of the Tandem Fibronectin Type 3 Domains of Neural Cell Adhesion Molecule
score: 4.0807731, Journal of Molecular Biology, 2008, Carafoli, Federico; Saffell, Jane L.; Hohenester, Erhard

The NKR-P1B gene product is an inhibitory receptor on SJL/J NK cells.
score: 4.079219, Journal of immunology (Baltimore, Md. : 1950), 1999, Kung, S K; Su, R C; Shannon, J; Miller, R G

Ligand-independent role of the beta 4 integrin subunit in the formation of hemidesmosomes.
score: 4.0786319, Journal of cell science, 1998, Nievers, M G et. al.

Mammary-derived growth inhibitor (MDGI) interacts with integrin α-subunits and suppresses integrin activity and invasion.
score: 4.0762526, Oncogene, 2010, Nevo, J et. al.

Adaptation of a DNA Replication Checkpoint Response Depends upon Inactivation of Claspin by the Polo-like Kinase
score: 4.0731375, Cell, 2004, Yoo, Hae Yong et. al.

Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation
score: 4.0729826, Arthritis Research, 1999, Ortmann, Robert A et. al.

Co-stimulation in T cell responses
score: 4.0720745, Current Opinion in Immunology, 1997, Chambers, Cynthia A; Allison, James P

Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization
score: 4.0707047, Cell, 1996, Symons, Marc et. al.

Crk and CrkL adaptor proteins: networks for physiological and pathological signaling
score: 4.0687732, Cell Communication and Signaling : CCS, 2009, Birge, Raymond B et. al.

P Bodies and the Control of mRNA Translation and Degradation
score: 4.0685979, Molecular Cell, 2007, Parker, Roy; Sheth, Ujwal

Extracellular matrix and its receptors in Drosophila neural development.
score: 4.0682807, Developmental neurobiology, 2011, Broadie, Kendal; Baumgartner, Stefan; Prokop, Andreas

Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signaling.
score: 4.0682155, Molecular and cellular biology, 1995, Drummond-Barbosa, D A et. al.

CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D 2-like receptors
score: 4.0675059, Molecular Brain Research, 2003, Griffon, Nathalie et. al.

High resolution mapping of mast cell membranes reveals primary and secondary domains of FcεRI and LAT
score: 4.06628, The Journal of Cell Biology, 2001, Wilson, Bridget S. et. al.

X-Ray Structures of Myc-Max and Mad-Max Recognizing DNA
score: 4.0655067, Cell, 2003, Nair, Satish K.; Burley, Stephen K.

Structure and mechanics of integrin-based cell adhesion
score: 4.065318, Current Opinion in Cell Biology, 2007, Arnaout, M Amin; Goodman, Simon L; Xiong, Jian-Ping

Protein Tyrosine Phosphatases and the Control of Cellular Signaling Responses
score: 4.0635222, Advances in Pharmacology, 1996, Tonks, N.K.

Virus-producing cells determine the host protein profiles of HIV-1 virion cores
score: 4.0622236, Retrovirology, 2012, Santos, Steven et. al.

Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization.
score: 4.0615458, Molecular and cellular biology, 2003, Valovka, Taras et. al.

A review of current proteomics technologies with a survey on their widespread use in reproductive biology investigations
score: 4.0610348, Theriogenology, 2012, Wright, P.C.; Noirel, J.; Ow, S.-Y.; Fazeli, A.

Agonist-induced phosphorylation by G protein-coupled receptor kinases of the EP4 receptor carboxyl-terminal domain in an EP3/EP4 prostaglandin E(2) receptor hybrid.
score: 4.0599248, Molecular pharmacology, 1999, Neuschäfer-Rube, F et. al.

Regulation of Phospholipase C‐γ2 Networks in B Lymphocytes
score: 4.0585287, Advances in Immunology, 2005, Hikida, Masaki; Kurosaki, Tomohiro

Regulation of Phospholipase C‐γ2 Networks in B Lymphocytes
score: 4.0585287, Advances in Immunology, 2005, Hikida, Masaki; Kurosaki, Tomohiro

NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction.
score: 4.0567667, Journal of immunology (Baltimore, Md. : 1950), 2006, Sasai, Miwa et. al.

Sequential Assembly of Centromeric Proteins in Male Mouse Meiosis
score: 4.0566506, PLoS Genetics, 2009, Parra, María Teresa et. al.

Ozz-E3, A Muscle-Specific Ubiquitin Ligase, Regulates β-Catenin Degradation during Myogenesis
score: 4.05508, Developmental Cell, 2004, Nastasi, Tommaso et. al.

A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton
score: 4.0543642, Current Biology, 1997, Aspenström, Pontus

Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes
score: 4.0540851, BMC Immunology, 2002, Hsueh, Robert C et. al.

The hunting of the Src.
score: 4.0530031, Nature reviews. Molecular cell biology, 2001, Martin, G S

The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor.
score: 4.051667, Proceedings of the National Academy of Sciences of the United States of America, 2006, Li, Guangtao et. al.

SH3P7 is a cytoskeleton adapter protein and is coupled to signal transduction from lymphocyte antigen receptors.
score: 4.0513583, Molecular and cellular biology, 1999, Larbolette, O et. al.

A minor tyrosine phosphorylation site located within the CAIN domain plays a critical role in regulating tissue-specific transformation by erbB kinase.
score: 4.0500346, Journal of virology, 1995, Chang, C M et. al.

NMR Structural Studies of the ItchWW3 Domain Reveal that Phosphorylation at T30 Inhibits the Interaction with PPxY-Containing Ligands
score: 4.0500256, Structure, 2007, Morales, Begoña et. al.

A novel member of the interferon receptor family complements functionality of the murine interferon γ receptor in human cells
score: 4.0500091, Cell, 1994, Hemmi, Silvio et. al.

Disease-associated mutations in L1 CAM interfere with ligand interactions and cell-surface expression.
score: 4.0487546, Human molecular genetics, 2002, De Angelis, Elena et. al.

Recruitment of the cytoplasmic adaptor Grb2 to surface IgG and IgE provides antigen receptor-intrinsic costimulation to class-switched B cells.
score: 4.0471255, Nature immunology, 2009, Engels, Niklas et. al.

Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts.
score: 4.0447069, British Journal of Cancer, 1993, Rygaard, K.; Nakamura, T.; Spang-Thomsen, M.

Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts.
score: 4.0447069, British journal of cancer, 1993, Rygaard, K; Nakamura, T; Spang-Thomsen, M

Fibroblast growth factor receptor 3 associates with and tyrosine phosphorylates p90 RSK2, leading to RSK2 activation that mediates hematopoietic transformation.
score: 4.04281, Molecular and cellular biology, 2009, Kang, Sumin et. al.

MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1
score: 4.0420413, Biochemical and Biophysical Research Communications, 2008, Nonaka, Hideo et. al.

Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase.
score: 4.0419389, Cell research, 2011, Gantke, Thorsten; Sriskantharajah, Srividya; Ley, Steven C

Reduced expression of (alpha)5(beta)1 integrin prevents spreading-dependent cell proliferation.
score: 4.0408846, Journal of cell science, 1999, Davey, G; Buzzai, M; Assoian, R K

Nef-Induced CD4 Degradation
score: 4.0403109, Cell, 1999, Piguet, Vincent et. al.

Nup153 is an M9-containing mobile nucleoporin with a novel Ran-binding domain.
score: 4.040026, The EMBO journal, 1999, Nakielny, S; Shaikh, S; Burke, B; Dreyfuss, G

Role of metazoan mediator proteins in interferon-responsive transcription.
score: 4.0359002, Molecular and cellular biology, 2003, Lau, Joe F et. al.

Increasing complexity of Ras signaling.
score: 4.0354242, Oncogene, 1998, Campbell, S L et. al.

Intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling.
score: 4.0346699, Molecular pharmacology, 2006, Martin, Negin P et. al.

VIPL, a VIP36-like membrane protein with a putative function in the export of glycoproteins from the endoplasmic reticulum☆
score: 4.0345371, Experimental Cell Research, 2003, Neve, Etienne P.A et. al.

Structure of the Tandem Fibronectin Type 3 Domains of Neural Cell Adhesion Molecule
score: 4.0343932, Journal of Molecular Biology, 2008, Carafoli, Federico; Saffell, Jane L.; Hohenester, Erhard

Diabetic neuropathy and nerve regeneration
score: 4.0343537, Progress in Neurobiology, 2003, Yasuda, Hitoshi et. al.

Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region.
score: 4.033292, Oncogene, 1998, Zisch, A H; Kalo, M S; Chong, L D; Pasquale, E B

Agonist-induced phosphorylation of the angiotensin AT1a receptor is localized to a serine/threonine-rich region of its cytoplasmic tail.
score: 4.0329418, Molecular pharmacology, 1998, Smith, R D et. al.

The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5.
score: 4.0325822, Journal of immunology (Baltimore, Md. : 1950), 2000, Lord, J D; McIntosh, B C; Greenberg, P D; Nelson, B H

Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain.
score: 4.0325416, Proceedings of the National Academy of Sciences of the United States of America, 1997, Noguchi, M et. al.

Autoimmunity
score: 4.0324393, Current Opinion in Immunology, 1996,

RGS13 controls g protein-coupled receptor-evoked responses of human mast cells.
score: 4.0322757, Journal of immunology (Baltimore, Md. : 1950), 2008, Bansal, Geetanjali et. al.

Functional interaction between the ubiquitin-specific protease 25 and the SYK tyrosine kinase
score: 4.0308774, Experimental Cell Research, 2010, Cholay, Michael et. al.

Crystal structure of inhibitor of κB kinase β (IKKβ)
score: 4.0300436, Nature, 2011, Xu, Guozhou et. al.

Cooperation between SHP-2, phosphatidyl inositol 3-kinase and phosphoinositol 5-phosphatase in the FcγRIIb mediated B cell regulation
score: 4.0292236, Immunology Letters, 1999, Sármay, Gabriella et. al.

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes.
score: 4.0263027, Molecular and cellular biology, 1998, Lundberg, A S; Weinberg, R A

5' to 3' mRNA decay factors colocalize with Ty1 gag and human APOBEC3G and promote Ty1 retrotransposition.
score: 4.0262994, Journal of virology, 2010, Dutko, James A et. al.

Transmembrane adaptor proteins in membrane microdomains: important regulators of immunoreceptor signaling
score: 4.0258099, Immunology Letters, 2004, Hořejšı́, Václav

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins.
score: 4.0253472, The EMBO journal, 1997, Frost, J A et. al.

Sorting of Golgi resident proteins into different subpopulations of COPI vesicles
score: 4.0250094, The Journal of Cell Biology, 2001, Lanoix, Joel et. al.

Protean effects of a natural peptide agonist of the G protein-coupled secretin receptor demonstrated by receptor mutagenesis.
score: 4.0244893, The Journal of pharmacology and experimental therapeutics, 1998, Ganguli, S C et. al.

15th International Symposium on Regulatory Peptides
score: 4.0228593, Regulatory Peptides, 2004,

cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation.
score: 4.0221988, Cancer research, 2009, Jin, Hyung-Seung et. al.

ULBPs, Novel MHC Class I–Related Molecules, Bind to CMV Glycoprotein UL16 and Stimulate NK Cytotoxicity through the NKG2D Receptor
score: 4.0205396, Immunity, 2001, Cosman, David et. al.

Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation.
score: 4.0192768, The EMBO journal, 2007, Hauge, Camilla et. al.

Slap negatively regulates Src mitogenic function but does not revert Src-induced cell morphology changes.
score: 4.0192685, Molecular and cellular biology, 2000, Manes, G; Bello, P; Roche, S

Conservation and divergence of axon guidance mechanisms
score: 4.0184585, Current Opinion in Neurobiology, 1999, Chisholm, Andrew; Tessier-Lavigne, Marc

Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway
score: 4.0117472, Virology, 2007, Georgel, Philippe et. al.

Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae.
score: 4.0110119, Journal of immunology (Baltimore, Md. : 1950), 2011, Boyle, Keith B et. al.

A Unified Model for Apical Caspase Activation
score: 4.0083042, Molecular Cell, 2003, Boatright, Kelly M et. al.

Two different epitopes of the signal transducer gp130 sequentially cooperate on IL-6-induced receptor activation.
score: 4.0082728, Journal of immunology (Baltimore, Md. : 1950), 2000, Pflanz, S et. al.

An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.
score: 4.0050164, Oncogene, 1997, Fujitani, Y et. al.

Differential regulation of leukemia inhibitory factor-stimulated neuronal gene expression by protein phosphatases SHP-1 and SHP-2 through mitogen-activated protein kinase-dependent and -independent pathways.
score: 4.004905, Journal of neurochemistry, 2000, Bartoe, J L; Nathanson, N M

Serine 34 Phosphorylation of Rho Guanine Dissociation Inhibitor (RhoGDIα) Links Signaling from Conventional Protein Kinase C to RhoGTPase in Cell Adhesion *
score: 4.0022942, The Journal of Biological Chemistry, 2010, Dovas, Athanassios et. al.

The death effector domain protein family.
score: 4.0008159, Oncogene, 2003, Barnhart, Bryan C et. al.

Requirement for phospholipase C-gamma1 enzymatic activity in growth factor-induced mitogenesis.
score: 3.9981111, Molecular and cellular biology, 1998, Wang, Z; Glück, S; Zhang, L; Moran, M F

Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system.
score: 3.9971707, Journal of immunology (Baltimore, Md. : 1950), 2005, Okazawa, Hideki et. al.

Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.
score: 3.9967886, The EMBO journal, 2001, Itoh, Y et. al.

Direct binding of p85 to sst2 somatostatin receptor reveals a novel mechanism for inhibiting PI3K pathway.
score: 3.9961013, The EMBO journal, 2006, Bousquet, Corinne et. al.

Activation of Natural Killer Cells and Dendritic Cells upon Recognition of a Novel CD99-like Ligand by Paired Immunoglobulin-like Type 2 Receptor
score: 3.9959816, The Journal of Experimental Medicine, 2004, Shiratori, Ikuo et. al.

Adaptor proteins in lymphocyte antigen-receptor signaling
score: 3.9934779, Current Opinion in Immunology, 1998, Peterson, Erik J et. al.

Adaptor usage and Toll-like receptor signaling specificity
score: 3.9925096, FEBS Letters, 2005, Dunne, Aisling; O’Neill, Luke A.J.

TFIIH Plays an Essential Role in RNA Polymerase I Transcription
score: 3.9919509, Cell, 2002, Iben, Sebastian et. al.

Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor Shc.
score: 3.9898516, The EMBO journal, 1997, Kranenburg, O; Verlaan, I; Hordijk, P L; Moolenaar, W H

Quantitative Changes in Integrin and Focal Adhesion Signaling Regulate Myoblast Cell Cycle Withdrawal
score: 3.9890336, The Journal of Cell Biology, 1999, Sastry, Sarita K. et. al.

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.
score: 3.9863915, Proceedings of the National Academy of Sciences of the United States of America, 2006, Rowe, Daniel C et. al.

Transcriptional activation domains of human heat shock factor 1 recruit human SWI/SNF.
score: 3.9845774, Molecular and cellular biology, 2001, Sullivan, E K et. al.

Emerging functions of p21-activated kinases in human cancer cells.
score: 3.9843399, Journal of cellular physiology, 2002, Kumar, Rakesh; Vadlamudi, Ratna K

Generation of pro-T cells in vitro: potential for immune reconstitution
score: 3.9841568, Seminars in Immunology, 2007, Awong, Génève et. al.

LAB/NTAL/Lat2: a force to be reckoned with in all leukocytes?
score: 3.9830926, Journal of leukocyte biology, 2011, Orr, Selinda J; McVicar, Daniel W

Incorporation of Galpha(z)-specific sequence at the carboxyl terminus increases the promiscuity of galpha(16) toward G(i)-coupled receptors.
score: 3.9824445, Molecular pharmacology, 2000, Mody, S M; Ho, M K; Joshi, S A; Wong, Y H

Identification of a binding site in c-Ab1 tyrosine kinase for the C-terminal repeated domain of RNA polymerase II.
score: 3.9802889, Molecular and cellular biology, 1996, Baskaran, R; Chiang, G G; Wang, J Y

Nuclear Import of Cdk/Cyclin Complexes: Identification of Distinct Mechanisms for Import of Cdk2/Cyclin E and Cdc2/Cyclin B1
score: 3.9775325, The Journal of Cell Biology, 1999, Moore, Jonathan D. et. al.

The Cdc20 (Fzy)/Cdh1-related protein, Cort, cooperates with Fzy in cyclin destruction and anaphase progression in meiosis I and II in Drosophila.
score: 3.9750736, Development (Cambridge, England), 2007, Swan, Andrew; Schüpbach, Trudi

Rhodopsin and its kinase
score: 3.9749656, Methods in Enzymology, 2002, Sokal, Izabela et. al.

Rhodopsin and its kinase
score: 3.9749656, Methods in Enzymology, 2002, Sokal, Izabela et. al.

T-cell activation through the antigen receptor. Part 1: Signaling components, signaling pathways, and signal integration at the T-cell antigen receptor synapse
score: 3.9748859, The Journal of Allergy and Clinical Immunology, 2002, Nel, Andre E.

A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration.
score: 3.9747321, The EMBO journal, 2000, Gille, H et. al.

Nuclear Import of Human Immunodeficiency Virus Type-1 Preintegration Complexes
score: 3.9746434, Advances in Virus Research, 1999, Fouchier, Ron A.M.; Malim, Michael H.

Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit.
score: 3.9731849, Molecular and cellular biology, 1994, Jenny, A; Hauri, H P; Keller, W

Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor
score: 3.9713489, The Journal of Cell Biology, 2010, Goh, Lai Kuan et. al.

TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker.
score: 3.9713441, Journal of immunology (Baltimore, Md. : 1950), 2005, Jung, Dae Young et. al.

Keratinocyte Growth Factor⧸Fibroblast Growth Factor 7, a Homeostatic Factor with Therapeutic Potential for Epithelial Protection and Repair
score: 3.971058, Advances in Cancer Research, 2004, Finch, Paul W.; Rubin, Jeffrey S.

Keratinocyte Growth Factor⧸Fibroblast Growth Factor 7, a Homeostatic Factor with Therapeutic Potential for Epithelial Protection and Repair
score: 3.971058, Advances in Cancer Research, 2004, Finch, Paul W.; Rubin, Jeffrey S.

Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases
score: 3.9697895, Current Biology, 1995, Mayer, Bruce J.; Hirai, Hisamaru; Sakai, Ryuichi

The Epstein-Barr virus (EBV) deubiquitinating enzyme BPLF1 reduces EBV ribonucleotide reductase activity.
score: 3.9688221, Journal of virology, 2009, Whitehurst, Christopher B et. al.

An aberrant autocrine activation of the platelet-derived growth factor α-receptor in follicular and papillary thyroid carcinoma cell lines
score: 3.9676485, Cancer Letters, 2006, Chen, Kuei-Tien et. al.

Alternative Splicing in Oncogenic Kinases: From Physiological Functions to Cancer
score: 3.9671632, Journal of Nucleic Acids, 2011, Druillennec, Sabine; Dorard, Coralie; Eychène, Alain

Ubiquitin-Dependent Sorting into the Multivesicular Body Pathway Requires the Function of a Conserved Endosomal Protein Sorting Complex, ESCRT-I
score: 3.9648545, Cell, 2001, Katzmann, David J.; Babst, Markus; Emr, Scott D.

Essential role of PDK1 in regulating endothelial cell migration
score: 3.9647034, The Journal of Cell Biology, 2007, Primo, Luca et. al.

Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation.
score: 3.9634829, EMBO reports, 2002, Wan, Mei et. al.

Expression cloning of oligomerization-activated genes with cell-proliferating potency by pseudotype retrovirus vector
score: 3.9634039, Biochemical and Biophysical Research Communications, 2004, Abe, Akihiro et. al.

Invariant Chain-Induced B Cell Differentiation Requires Intramembrane Proteolytic Release of the Cytosolic Domain
score: 3.9633454, Immunity, 2002, Matza, Didi et. al.

The Anaphase-Promoting Complex
score: 3.9617468, Molecular Cell, 2002, Peters, Jan-Michael

The SH2-containing adapter protein GRB10 interacts with BCR-ABL.
score: 3.9616337, Oncogene, 1998, Bai, R Y et. al.

T-cell-receptor- and B-cell-receptor-mediated activation of NF-κB in lymphocytes
score: 3.9597896, Current Opinion in Immunology, 2004, Weil, Robert; Israël, Alain

Resistance of actin to cleavage during apoptosis.
score: 3.9593518, Proceedings of the National Academy of Sciences of the United States of America, 1997, Song, Q et. al.

Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?
score: 3.9587795, Trends in Biochemical Sciences, 2008, Chau, Tieu-Lan et. al.

Role of interferon alpha/beta receptor chain 1 in the structure and transmembrane signaling of the interferon alpha/beta receptor complex.
score: 3.9586956, Proceedings of the National Academy of Sciences of the United States of America, 1994, Constantinescu, S N et. al.

Dual phosphorylation of phosphoinositide 3-kinase adaptor Grb2-associated binder 2 is responsible for superoxide formation synergistically stimulated by Fc gamma and formyl-methionyl-leucyl-phenylalanine receptors in differentiated THP-1 cells.
score: 3.9568711, Journal of immunology (Baltimore, Md. : 1950), 2003, Momose, Haruka et. al.

Reduction of hypoxia-induced transcription through the repression of hypoxia-inducible factor-1alpha/aryl hydrocarbon receptor nuclear translocator DNA binding by the 90-kDa heat-shock protein inhibitor radicicol.
score: 3.9565519, Molecular pharmacology, 2002, Hur, Eunseon et. al.

Etk/Bmx Regulates Proteinase-Activated-Receptor1 (PAR 1 ) in Breast Cancer Invasion: Signaling Partners, Hierarchy and Physiological Significance
score: 3.9552877, PLoS ONE, 2010, Cohen, Irit et. al.

The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelial cells
score: 3.9548788, The Journal of Experimental Medicine, 1996,

Structural insights into the molecular mechanism of Ca 2+-dependent exocytosis
score: 3.9542996, Current Opinion in Neurobiology, 2000, Brunger, Axel T

MAP kinases and the control of nuclear events.
score: 3.9537839, Oncogene, 2007, Turjanski, A G; Vaqué, J P; Gutkind, J S

Role of phosphatases in lymphocyte activation
score: 3.9537349, Current Opinion in Immunology, 1997, Neel, Benjamin G

An ITIM-like motif within the CCK2 receptor sequence required for interaction with SHP-2 and the activation of the AKT pathway
score: 3.9522021, BBA - Molecular Cell Research, 2006, Vatinel, Sébastien et. al.

Regulation of Wnt/beta-catenin signaling by protein kinases.
score: 3.9516113, Developmental dynamics : an official publication of the American Association of Anatomists, 2010, Verheyen, Esther M; Gottardi, Cara J

Hormones, Lymphohemopoietic Cytokines and the Neuroimmune Axis
score: 3.9491966, Comparative Biochemistry and Physiology -- Part A: Physiology, 1997, Johnson, R.W.; Arkins, S.; Dantzer, R.; Kelley, K.W.

Phosphoinositide-dependent protein kinase 1, a sensor of protein conformation
score: 3.9487934, Trends in Biochemical Sciences, 2004, Biondi, Ricardo M.

Inhibitory Pathways Triggered by ITIM-Containing Receptors
score: 3.9481266, Advances in Immunology, 1999, Bolland, Silvia; Ravetch, Jeffrey V.

Approaches to Study Posttranslational Regulation of Intermediate Filament Proteins
score: 3.9463448, Methods in Cell Biology, 2004, Kochin, Vitaly et. al.

Approaches to Study Posttranslational Regulation of Intermediate Filament Proteins
score: 3.9463448, Methods in Cell Biology, 2004, Kochin, Vitaly et. al.

Oncogenic Ras and its role in tumor cell invasion and metastasis
score: 3.9462474, Seminars in Cancer Biology, 2004, Campbell, Paul M; Der, Channing J

The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading
score: 3.9457584, The Journal of Cell Biology, 2002, Degani, Simona et. al.

Gene profiles of THP-1 macrophages after in vitro exposure to respiratory (non-)sensitizing chemicals: Identification of discriminating genetic markers and pathway analysis
score: 3.9455103, Toxicology in Vitro, 2009, Verstraelen, Sandra et. al.

The Rac and Rho pathways as a source of drug targets for Ras-mediated malignancies
score: 3.9452673, Current Opinion in Biotechnology, 1995, Symons, Marc

Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner.
score: 3.945208, European journal of immunology, 2004, Rutz, Mark et. al.

Misfolded major histocompatibility complex class I molecules accumulate in an expanded ER-Golgi intermediate compartment
score: 3.9439285, The Journal of Cell Biology, 1995,

Hrt and Hes negatively regulate Notch signaling through interactions with RBP-Jκ
score: 3.9430704, Biochemical and Biophysical Research Communications, 2006, King, Isabelle N. et. al.

Biochemical markers in oncology. Part I: Molecular basis. Part II: Clinical uses
score: 3.942325, Cancer Treatment Reviews, 2007, Voorzanger-Rousselot, N.; Garnero, P.

KIT SIGNAL TRANSDUCTION
score: 3.9422692, Hematology/Oncology Clinics of North America, 2000, Taylor, Marcia L.; Metcalfe, Dean D.

Components of a stat recognition code: Evidence for two layers of molecular selectivity
score: 3.941965, Immunity, 1995, Schindler, Ulrike et. al.

PAR-1 Phosphorylates Mind Bomb to Promote Vertebrate Neurogenesis
score: 3.9399274, Developmental Cell, 2009, Ossipova, Olga; Ezan, Jerome; Sokol, Sergei Y.

Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration.
score: 3.9385726, Journal of cell science, 1999, Sieg, D J; Hauck, C R; Schlaepfer, D D

An LI and ML motif in the cytoplasmic tail of the MHC-associated invariant chain mediate rapid internalization.
score: 3.9377928, Journal of cell science, 1994, Bremnes, B; Madsen, T; Gedde-Dahl, M; Bakke, O

Raf kinases mediate the phosphorylation of eukaryotic translation elongation factor 1A and regulate its stability in eukaryotic cells.
score: 3.9368694, Cell death & disease, 2012, Sanges, C et. al.

The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products.
score: 3.9366845, Journal of leukocyte biology, 2000, Bowie, A; O'Neill, L A

FADD cleavage by NK cell granzyme M enhances its self-association to facilitate procaspase-8 recruitment for auto-processing leading to caspase cascade.
score: 3.9345073, Cell death and differentiation, 2012, Wang, S; Xia, P; Shi, L; Fan, Z

Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop.
score: 3.9337793, Molecular and cellular biology, 2009, Seo, Ji-Heui et. al.

Intracellular Proteinases of Invertebrates: Calcium-Dependent and Proteasome/Ubiquitin-Dependent Systems
score: 3.9327014, International Review of Cytology, 1998, Mykles, Donald L.

Intracellular Proteinases of Invertebrates: Calcium-Dependent and Proteasome/Ubiquitin-Dependent Systems
score: 3.9327014, International Review of Cytology, 1998, Mykles, Donald L.

Site-specific ubiquitination exposes a linear motif to promote interferon-α receptor endocytosis
score: 3.9325013, The Journal of Cell Biology, 2007, Kumar, K.G. Suresh et. al.

Critical role of phospholipase Cγ2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis
score: 3.9318637, The Journal of Experimental Medicine, 2009, Jakus, Zoltán et. al.

Katanin, a Microtubule-Severing Protein, Is a Novel AAA ATPase that Targets to the Centrosome Using a WD40-Containing Subunit
score: 3.9304192, Cell, 1998, Hartman, James J et. al.

Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1.
score: 3.9295562, Proceedings of the National Academy of Sciences of the United States of America, 1999, Wise, L M et. al.

Divalent cations regulate the folding and activation status of integrins during their intracellular trafficking.
score: 3.9286607, Journal of cell science, 2011, Tiwari, Shweta et. al.

Interaction of casein kinase 1 delta (CK1δ) with post-Golgi structures, microtubules and the spindle apparatus
score: 3.9284925, European Journal of Cell Biology, 2000, Behrend, Lars et. al.

Spatial Separation of HLA-DM/HLA-DR Interactions within MIIC and Phagosome-Induced Immune Escape
score: 3.9282906, Immunity, 2005, Zwart, Wilbert et. al.

Complex effects of naturally occurring mutations in the JAK3 pseudokinase domain: evidence for interactions between the kinase and pseudokinase domains.
score: 3.9279584, Molecular and cellular biology, 2000, Chen, M et. al.

Signal Transduction at Point-Blank Range: Analysis of a Spatial Coupling Mechanism for Pathway Crosstalk
score: 3.9271806, Biophysical Journal, 2008, Monine, Michael I.; Haugh, Jason M.

A critical role for cyclin C in promotion of the hematopoietic cell cycle by cooperation with c-Myc.
score: 3.9268572, Molecular and cellular biology, 1998, Liu, Z J et. al.

The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation site
score: 3.926237, BMC Biochemistry, 2006, de Graaf, Katrin et. al.

Chapter 2 New Insights into the Roles of Dendritic Cells in Intestinal Immunity and Tolerance
score: 3.9252729, International Review of Cell and Molecular Biology, 2008, Cerovic, Vuk et. al.

Chapter 2 New Insights into the Roles of Dendritic Cells in Intestinal Immunity and Tolerance
score: 3.9252729, International Review of Cell and Molecular Biology, 2008, Cerovic, Vuk et. al.

Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3
score: 3.9239485, The Journal of Cell Biology, 1996,

Pak1 Kinase Homodimers Are Autoinhibited in trans and Dissociated upon Activation by Cdc42 and Rac1
score: 3.923864, Molecular Cell, 2002, Parrini, Maria Carla et. al.

Inhibitory Pathways Triggered by ITIM-Containing Receptors
score: 3.9230086, Advances in Immunology, 1999, Bolland, Silvia; Ravetch, Jeffrey V.

FGFR4 and its novel splice form in myogenic cells: Interplay of glycosylation and tyrosine phosphorylation.
score: 3.9215474, Journal of cellular physiology, 2008, Kwiatkowski, Boguslaw A et. al.

Membranes and sorting
score: 3.9212107, Current Opinion in Cell Biology, 1996,

The JAK-STAT Pathway at Twenty
score: 3.9210214, Immunity, 2012, Stark, George R.; Darnell, James E.

Immunoglobulin superfamily receptors: cis-interactions, intracellular adapters and alternative splicing regulate adhesion
score: 3.9193517, Current Opinion in Cell Biology, 2001, Brümmendorf, Thomas; Lemmon, Vance

Teleost TLR22 recognizes RNA duplex to induce IFN and protect cells from birnaviruses.
score: 3.9191614, Journal of immunology (Baltimore, Md. : 1950), 2008, Matsuo, Aya et. al.

Antigen receptor signalling: a distinctive role for the p110δ isoform of PI3K
score: 3.9191107, Trends in Immunology, 2007, Okkenhaug, Klaus; Ali, Khaled; Vanhaesebroeck, Bart

Antigen receptor signalling: a distinctive role for the p110δ isoform of PI3K
score: 3.9191107, Trends in Immunology, 2007, Okkenhaug, Klaus; Ali, Khaled; Vanhaesebroeck, Bart

Blockade of natural killer cell-mediated lysis by NCAM140 expressed on tumor cells.
score: 3.9182849, International journal of cancer. Journal international du cancer, 2007, Jarahian, Mostafa et. al.

The regulation of mRNA stability in mammalian cells: 2.0
score: 3.9180143, Gene, 2012, Wu, Xiangyue; Brewer, Gary

The regulation of mRNA stability in mammalian cells: 2.0
score: 3.9180143, Gene, 2012, Wu, Xiangyue; Brewer, Gary

Regulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning.
score: 3.9170609, The EMBO journal, 2004, Sun, Huaiyu et. al.

Suppressor of cytokine signaling 3 controls lysosomal routing of G-CSF receptor.
score: 3.9155461, The EMBO journal, 2007, Irandoust, Mahban I et. al.

Su(dx) E3 ubiquitin ligase–dependent and –independent functions of Polychaetoid, the Drosophila ZO-1 homologue
score: 3.9152576, The Journal of Cell Biology, 2011, Djiane, Alexandre et. al.

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
score: 3.9151988, Molecular and cellular biology, 2004, Zhang, Donna D et. al.

PKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2.
score: 3.9143527, The EMBO journal, 2002, Lynch, Danielle K; Daly, Roger J

Optimization of the MHC Class I Peptide Cargo Is Dependent on Tapasin
score: 3.9141818, Immunity, 2002, Williams, Anthony P et. al.

A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor.
score: 3.9110062, Molecular and cellular biology, 1993, Ponzetto, C et. al.

Cell migration is regulated by platelet-derived growth factor receptor endocytosis.
score: 3.9062004, Molecular and cellular biology, 2009, Kawada, Kenji et. al.

Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins
score: 3.9055881, The Journal of Cell Biology, 1996,

Matriptase Is Involved in ErbB-2-Induced Prostate Cancer Cell Invasion
score: 3.9053964, The American Journal of Pathology, 2010, Wu, Shang-Ru et. al.

The Bcr–Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway
score: 3.9046451, Cellular Signalling, 2010, Preisinger, Christian; Kolch, Walter

The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis
score: 3.9038883, BBA - Molecular Cell Research, 2010, Martelli, Alberto M. et. al.

Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding.
score: 3.9033823, The EMBO journal, 1999, Munck Petersen, C et. al.

A Notch feeling of somite segmentation and beyond
score: 3.9029888, Developmental Biology, 2004, Rida, Padmashree C.G; Le Minh, Nguyet; Jiang, Yun-Jin

Cross talk of pp125(FAK) and pp59(Lyn) non-receptor tyrosine kinases to insulin-mimetic signaling in adipocytes.
score: 3.9000578, Molecular and cellular biology, 2000, Müller, G; Wied, S; Frick, W

Multilayered Mechanism of CD4 Downregulation by HIV-1 Vpu Involving Distinct ER Retention and ERAD Targeting Steps
score: 3.8981561, PLoS Pathogens, 2010, Magadán, Javier G. et. al.

Dynamic control of signaling by modular adaptor proteins
score: 3.8978381, Current Opinion in Cell Biology, 2007, Pawson, Tony

Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop.
score: 3.897495, Molecular and cellular biology, 2001, Garrett, S et. al.

Tyrosine phosphorylation of ACK in response to temperature shift-down, hyperosmotic shock, and epidermal growth factor stimulation
score: 3.8959284, FEBS Letters, 1996, Satoh, Takaya et. al.

Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes.
score: 3.8958026, Molecular and cellular biology, 1999, McConnell, B B; Gregory, F J; Stott, F J; Hara, E; Peters, G

Heterotrimeric C proteins: Organizers of transmembrane signals
score: 3.8956134, Cell, 1995, Neer, Eva J

Tyrosine Phosphorylation at a Site Highly Conserved in the L1 Family of Cell Adhesion Molecules Abolishes Ankyrin Binding and Increases Lateral Mobility of Neurofascin
score: 3.8949055, The Journal of Cell Biology, 1997, Garver, Timothy D.; Ren, Qun; Tuvia, Shmuel; Bennett, Vann

Caspases — An update
score: 3.8936986, Comparative Biochemistry and Physiology, Part B, 2008, Chowdhury, Indrajit; Tharakan, Binu; Bhat, Ganapathy K.

Insulin-like Growth Factor Binding Proteins
score: 3.8930271, Vitamins and Hormones, 1993, Rechler, Matthew M.

Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells
score: 3.8927732, Biochemical and Biophysical Research Communications, 2003, Kumagai, Hidetoshi et. al.

JAM-L–mediated leukocyte adhesion to endothelial cells is regulated in cis by α4β1 integrin activation
score: 3.8924797, The Journal of Cell Biology, 2008, Luissint, Anny-Claude et. al.

Integrin signalling at a glance.
score: 3.892161, Journal of cell science, 2009, Harburger, David S; Calderwood, David A

Subcellular recruitment by TSG118 and TSPYL implicates a role for zinc finger protein 106 in a novel developmental pathway
score: 3.890924, International Journal of Biochemistry and Cell Biology, 2005, Grasberger, Helmut; Bell, Graeme I.

Cbl-b Is a Negative Regulator of Receptor Clustering and Raft Aggregation in T Cells
score: 3.8904228, Immunity, 2000, Krawczyk, Connie et. al.

Trk activation in the secretory pathway promotes Golgi fragmentation
score: 3.8900155, Molecular and Cellular Neuroscience, 2010, Schecterson, Leslayann C. et. al.

EGFL7 meets miRNA-126: an angiogenesis alliance
score: 3.8890589, Journal of Angiogenesis Research, 2010, Nikolic, Iva; Plate, Karl-Heinz; Schmidt, Mirko HH

Superoxide and Derived Reactive Oxygen Species in the Regulation of Hypoxia‐Inducible Factors
score: 3.8883997, Methods in Enzymology, 2007, Görlach, Agnes; Kietzmann, Thomas

Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity.
score: 3.8876387, Journal of immunology (Baltimore, Md. : 1950), 1995, Ling, P et. al.

The close homologue of the neural adhesion molecule L1 (CHL1): patterns of expression and promotion of neurite outgrowth by heterophilic interactions.
score: 3.886891, The European journal of neuroscience, 1999, Hillenbrand, R; Molthagen, M; Montag, D; Schachner, M

Contributions of Wiskott-Aldrich syndrome family cytoskeletal regulatory adapters to immune regulation.
score: 3.8848576, Immunological reviews, 2009, Zhang, Jinyi; Dong, Baoxia; Siminovitch, Katherine A

Geminin is bound to chromatin in G2/M phase to promote proper cytokinesis
score: 3.8835732, International Journal of Biochemistry and Cell Biology, 2006, Nakuci, Enkeleda et. al.

Expression systems
score: 3.8819259, Current Opinion in Biotechnology, 1995,

SPECIFICITY OF PERIPHERAL NERVE REGENERATION: INTERACTIONS AT THE AXON LEVEL
score: 3.8806541, Progress in Neurobiology, 2012, Allodi, Ilary; Udina, Esther; Navarro, Xavier

Lung epithelium as a sentinel and effector system in pneumonia – molecular mechanisms of pathogen recognition and signal transduction
score: 3.8802778, Respiratory Research, 2006, Hippenstiel, Stefan et. al.

Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination
score: 3.878832, The Journal of Cell Biology, 2006, Pak, Youngshil et. al.

Regulation of IRSp53-dependent filopodial dynamics by antagonism between 14-3-3 binding and SH3-mediated localization.
score: 3.875799, Molecular and cellular biology, 2010, Robens, Jeffrey M et. al.

In vitro and in vivo activity of novel small-molecule inhibitors targeting the pleckstrin homology domain of protein kinase B/AKT.
score: 3.8753662, Cancer research, 2009, Moses, Sylvestor A et. al.

Requirement of Tumor Necrosis Factor Receptor–Associated Factor (Traf)6 in Interleukin 17 Signal Transduction
score: 3.874352, The Journal of Experimental Medicine, 2000, Schwandner, Ralf; Yamaguchi, Kyoko; Cao, Zhaodan

TLR signalling and activation of IRFs: revisiting old friends from the NF-κB pathway
score: 3.8732095, Trends in Immunology, 2005, Moynagh, Paul N.

PDGF signaling in cells and mice
score: 3.8724377, Cytokine and Growth Factor Reviews, 2004, Tallquist, Michelle; Kazlauskas, Andrius

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.
score: 3.8703967, Proceedings of the National Academy of Sciences of the United States of America, 1996, Fernandes-Alnemri, T et. al.

The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.
score: 3.8703604, Genes, chromosomes & cancer, 2002, de Bruijn, Diederik R H et. al.

The carboxyl-terminal SH3 domain of the mammalian adaptor CrkII promotes internalization of Listeria monocytogenes through activation of host phosphoinositide 3-kinase.
score: 3.8691227, Cellular microbiology, 2007, Dokainish, Hatem et. al.

Endoproteolytic processing of the lymphocytic choriomeningitis virus glycoprotein by the subtilase SKI-1/S1P.
score: 3.8691178, Journal of virology, 2003, Beyer, Winfried R et. al.

Positive feedback between Cdc42 activity and H + efflux by the Na-H exchanger NHE1 for polarity of migrating cells
score: 3.86893, The Journal of Cell Biology, 2007, Frantz, Christian et. al.

Modulation of Akt kinase activity by binding to Hsp90.
score: 3.8675578, Proceedings of the National Academy of Sciences of the United States of America, 2000, Sato, S; Fujita, N; Tsuruo, T

Tyrosine and serine phosphorylation of the neural cell adhesion molecule L1 is implicated in its oligomannosidic glycan dependent association with NCAM and neurite outgrowth
score: 3.8643564, European Journal of Cell Biology, 1998, Heiland, Petra Cornelia et. al.

Cdc2-like Kinase 2 Is an Insulin-Regulated Suppressor of Hepatic Gluconeogenesis
score: 3.8629872, Cell Metabolism, 2010, Rodgers, Joseph T. et. al.

The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress.
score: 3.8616029, Molecular and cellular biology, 2008, Mikhaylova, Olga et. al.

CSF-1 stimulation induces the formation of a multiprotein complex including CSF-1 receptor, c-Cbl, PI 3-kinase, Crk-II and Grb2.
score: 3.8615198, Oncogene, 1997, Husson, H et. al.

Targeting c-Kit mutations: basic science to novel therapies
score: 3.8610677, Leukemia Research, 2004, Sattler, Martin; Salgia, Ravi

Critical nodes in signalling pathways: insights into insulin action.
score: 3.860738, Nature reviews. Molecular cell biology, 2006, Taniguchi, Cullen M; Emanuelli, Brice; Kahn, C Ronald

Conformational switch and role of phosphorylation in PAK activation.
score: 3.8593644, Molecular and cellular biology, 2001, Buchwald, G et. al.

Shepherding AKT and androgen receptor by Ack1 tyrosine kinase.
score: 3.8589619, Journal of cellular physiology, 2010, Mahajan, Kiran; Mahajan, Nupam P

Polysialic acid directs tumor cell growth by controlling heterophilic neural cell adhesion molecule interactions.
score: 3.8574853, Molecular and cellular biology, 2003, Seidenfaden, Ralph et. al.

Ubiquitin: structures, functions, mechanisms
score: 3.8560274, BBA - Molecular Cell Research, 2004, Pickart, Cecile M.; Eddins, Michael J.

The MHC class II-associated invariant chain contains two endosomal targeting signals within its cytoplasmic tail.
score: 3.8550427, Journal of cell science, 1993, Pieters, J; Bakke, O; Dobberstein, B

Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family
score: 3.8545579, FEBS Letters, 2000, Vayssière, Béatrice et. al.

Lymphoid/Neuronal Cell Surface OX2 Glycoprotein Recognizes a Novel Receptor on Macrophages Implicated in the Control of Their Function
score: 3.851999, Immunity, 2000, Wright, Gavin J et. al.

PC12 cell activation by epidermal growth factor receptor: role of autophosphorylation sites
score: 3.8509126, International Journal of Developmental Neuroscience, 2003, Tyson, Darren R et. al.

Early Activation of Caspases during T Lymphocyte Stimulation Results in Selective Substrate Cleavage in Nonapoptotic Cells
score: 3.8506718, The Journal of Experimental Medicine, 1999, Alam, Antoine et. al.

Motor axon migration: a long way to go
score: 3.8497166, Developmental Biology, 2003, Schneider, Valerie A; Granato, Michael

Assembly and Signaling of Adhesion Complexes
score: 3.8487374, Current Topics in Developmental Biology, 2005, Sepulveda, Jorge L.; Gkretsi, Vasiliki; Wu, Chuanyue

Assembly and Signaling of Adhesion Complexes
score: 3.8487374, Current Topics in Developmental Biology, 2005, Sepulveda, Jorge L.; Gkretsi, Vasiliki; Wu, Chuanyue

EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2.
score: 3.8484227, Oncogene, 1997, Douville, E; Downward, J

The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1
score: 3.8466969, Current Biology, 1998, Wu, Yongjian et. al.

Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution
score: 3.846506, Biology Direct, 2010, Cavalier-Smith, Thomas

HIV accessory proteins: Multifunctional components of a complex system
score: 3.845861, Advances in Pharmacology, 2000, Bour, Stephan; Strebel, Klaus

A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos
score: 3.8444196, Cell, 1993, Olivier, Jean Paul et. al.

Function of the c-Myc Oncogenic Transcription Factor
score: 3.8428086, Experimental Cell Research, 1999, Dang, Chi V. et. al.

Cytotoxic T Lymphocyte Antigen 4 (Ctla-4) Engagement Delivers an Inhibitory Signal through the Membrane-Proximal Region in the Absence of the Tyrosine Motif in the Cytoplasmic Tail
score: 3.8424366, The Journal of Experimental Medicine, 1999, Nakaseko, Chiaki et. al.

AP-1 function and regulation
score: 3.8417352, Current Opinion in Cell Biology, 1997, Karin, Michael; Liu, Zheng-gang; Zandi, Ebrahim

Human TPX2 is required for targeting Aurora-A kinase to the spindle
score: 3.8411457, The Journal of Cell Biology, 2002, Kufer, Thomas A. et. al.

Serum and Insulin Induce a Grb2-Dependent Shift in Agonist Affinity of β-Adrenergic Receptors
score: 3.840859, Cellular Signalling, 1998, Shih, Meiling; Malbon, Craig C

Progesterone Receptor Contains a Proline-Rich Motif that Directly Interacts with SH3 Domains and Activates c-Src Family Tyrosine Kinases
score: 3.8397819, Molecular Cell, 2001, Boonyaratanakornkit, Viroj et. al.

Assembly of turnip yellow mosaic virus replication complexes: interaction between the proteinase and polymerase domains of the replication proteins.
score: 3.8388401, Journal of virology, 2004, Jakubiec, Anna et. al.

VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2
score: 3.8349879, Experimental Cell Research, 2007, Garrett, Tiana A.; Van Buul, Jaap D.; Burridge, Keith

Ubiquitination of E3 ligases: self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanisms.
score: 3.8334845, Cell death and differentiation, 2011, de Bie, P; Ciechanover, A

Ligand-dependent inhibition of beta-catenin/TCF signaling by androgen receptor.
score: 3.8328734, Oncogene, 2002, Chesire, Dennis R; Isaacs, William B

Role of the Ubiquitin–Proteasome in Protein Quality Control and Signaling-Chapter 10:Implication in the Pathogenesis of Eye Diseases
score: 3.8327174, Progress in Molecular Biology and Translational Science, 2012, Shang, Fu; Taylor, Allen

Tec protein-tyrosine kinase is an effector molecule of Lyn protein-tyrosine kinase.
score: 3.832416, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1996, Mano, H; Yamashita, Y; Miyazato, A; Miura, Y; Ozawa, K

Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function.
score: 3.8308928, Journal of immunology (Baltimore, Md. : 1950), 2004, Wu, Jennifer N et. al.

Human matrix metalloproteinases: An ubiquitarian class of enzymes involved in several pathological processes
score: 3.8302985, Molecular Aspects of Medicine, 2012, Sbardella, Diego et. al.

Paxillin LD4 Motif Binds PAK and PIX through a Novel 95-kD Ankyrin Repeat, ARF–GAP Protein: A Role in Cytoskeletal Remodeling
score: 3.8299251, The Journal of Cell Biology, 1999, Turner, Christopher E. et. al.

Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression.
score: 3.8298323, Journal of immunology (Baltimore, Md. : 1950), 1997, Chuang, E et. al.

DNA-activated protein kinase functions in a newly observed S phase checkpoint that links histone mRNA abundance with DNA replication
score: 3.8294435, The Journal of Cell Biology, 2007, Müller, Berndt et. al.

Suppression of fibroblast growth factor receptor signaling inhibits pancreatic cancer growth in vitro and in vivo
score: 3.8293582, Gastroenterology, 1998, Wagner, Markus; Lopez, Martha E.; Cahn, Mitch; Korc, Murray

Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2
score: 3.8292588, Retrovirology, 2011, Olivieri, Kevin C; Mukerji, Joya; Gabuzda, Dana

Acetylation-Dependent Signal Transduction for Type I Interferon Receptor
score: 3.8278656, Cell, 2007, Tang, Xiaoli et. al.

Docking proteins.
score: 3.8270358, The FEBS journal, 2010, Brummer, Tilman; Schmitz-Peiffer, Carsten; Daly, Roger J

Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses.
score: 3.8251544, Journal of immunology (Baltimore, Md. : 1950), 2000, Wyllie, D H et. al.

Ubiquitination of the bacterial inositol phosphatase, SopB, regulates its biological activity at the plasma membrane
score: 3.8249805, Cellular Microbiology, 2009, Knodler, Leigh A et. al.

Gastrin induces tyrosine phosphorylation of Shc proteins and their association with the Grb2/Sos complex
score: 3.8237545, FEBS Letters, 1996, Seva, Catherine et. al.

PSA-NCAM in mammalian structural plasticity and neurogenesis
score: 3.8228461, Progress in Neurobiology, 2006, Bonfanti, Luca

NEDD1-dependent recruitment of the γ-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly
score: 3.822811, The Journal of Cell Biology, 2006, Haren, Laurence et. al.

The role of the adapter molecule SLP-76 in platelet function.
score: 3.8227547, Oncogene, 2001, Judd, B A; Koretzky, G A

CTL-associated antigen-4 ligation induces rapid T cell polarization that depends on phosphatidylinositol 3-kinase, Vav-1, Cdc42, and myosin light chain kinase.
score: 3.8224688, Journal of immunology (Baltimore, Md. : 1950), 2007, Wei, Bin et. al.

Structure-function analysis of delta trafficking, receptor binding and signaling in Drosophila.
score: 3.8221299, Genetics, 2006, Parks, Annette L et. al.

Disulfide bonds determine growth hormone receptor folding, dimerisation and ligand binding.
score: 3.8213887, Journal of cell science, 2006, van den Eijnden, Monique J M; Lahaye, Liza L; Strous, Ger J

Structural and Functional Characterization of the NHR1 Domain of the Drosophila Neuralized E3 Ligase in the Notch Signaling Pathway
score: 3.8185091, Journal of Molecular Biology, 2009, He, Fahu et. al.

Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia
score: 3.8183136, Developmental Biology, 2008, Yang, Xuehui et. al.

Localization of the Rsp5p ubiquitin-protein ligase at multiple sites within the endocytic pathway.
score: 3.8168867, Molecular and cellular biology, 2001, Wang, G et. al.

HES and HERP families: multiple effectors of the Notch signaling pathway.
score: 3.8146441, Journal of cellular physiology, 2003, Iso, Tatsuya; Kedes, Larry; Hamamori, Yasuo

p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD.
score: 3.8133164, Molecular and cellular biology, 2003, Cotteret, Sophie et. al.

PH-domain-driven targeting of collybistin but not Cdc42 activation is required for synaptic gephyrin clustering.
score: 3.8098601, The European journal of neuroscience, 2010, Reddy-Alla, Suneel et. al.

Structural and functional coupling of Hsp90- and Sgt1-centred multi-protein complexes
score: 3.8092665, The EMBO Journal, 2008, Zhang, Minghao et. al.

Association of terminal deoxynucleotidyl transferase with Ku.
score: 3.8091832, Proceedings of the National Academy of Sciences of the United States of America, 1999, Mahajan, K N et. al.

Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization.
score: 3.8089525, Journal of immunology (Baltimore, Md. : 1950), 2010, Gross, Catharina C et. al.

echinus , required for interommatidial cell sorting and cell death in the Drosophila pupal retina, encodes a protein with homology to ubiquitin-specific proteases
score: 3.8085156, BMC Developmental Biology, 2007, Copeland, Jeffrey M et. al.

Fibroblast growth factor signaling in development of the cerebral cortex.
score: 3.8083225, Development, growth & differentiation, 2009, Iwata, Tomoko; Hevner, Robert F

The SH3 domain of p56lck binds to proline-rich sequences in the cytoplasmic domain of CD2
score: 3.8069544, The Journal of Experimental Medicine, 1996,

The Innate Antiviral Response: New Insights Into A Continuing Story
score: 3.8068504, Advances in Virus Research, 2006, Paun, Andrea; Pitha, Paula M.

Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor
score: 3.8067867, Cell, 1998, Soker, Shay et. al.

Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1
score: 3.8059754, Current Biology, 1998, Cohen, N.R. et. al.

Identification of RANBP16 and RANBP17 as novel interaction partners for the bHLH transcription factor E12.
score: 3.8054015, Journal of cellular biochemistry, 2010, Lee, Jun-Ho; Zhou, Shengli; Smas, Cynthia M

Identification of PLCγ-Dependent and -Independent Events during Fertilization of Sea Urchin Eggs
score: 3.8052025, Developmental Biology, 1999, Carroll, David J. et. al.

Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors.
score: 3.8043518, Stem cells (Dayton, Ohio), 1998, Guthridge, M A et. al.

Internalization of LDL-receptor superfamily yolk-protein receptors during mosquito oogenesis involves transcriptional regulation of PTB-domain adaptors.
score: 3.8036166, Journal of cell science, 2008, Mishra, Sanjay K et. al.

Insulin dependent tyrosine phosphorylation of the tyrosine internalisation motif of TGN38 creates a specific SH2 domain binding site
score: 3.8033407, FEBS Letters, 1997, Stephens, D.J; Banting, G

Insulin dependent tyrosine phosphorylation of the tyrosine internalisation motif of TGN38 creates a specific SH2 domain binding site
score: 3.8033407, FEBS Letters, 1997, Stephens, D.J; Banting, G

Actions of TGF-β as tumor suppressor and pro-metastatic factor in human cancer
score: 3.8016495, BBA - Reviews on Cancer, 2007, Pardali, Katerina; Moustakas, Aristidis

Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites.
score: 3.8000888, Journal of cell science, 2004, Haglund, Kaisa et. al.

A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking.
score: 3.799648, The EMBO journal, 2006, Scott, Gregory K et. al.

Nuclear import of Upf3p is mediated by importin-alpha/-beta and export to the cytoplasm is required for a functional nonsense-mediated mRNA decay pathway in yeast.
score: 3.7993679, Genetics, 2002, Shirley, Renee L et. al.

Identification of human activin and TGFβ type I receptors that form heteromeric kinase complexes with type II receptors
score: 3.7990217, Cell, 1993, Attisano, Liliana et. al.

FIGQY phosphorylation defines discrete populations of L1 cell adhesion molecules at sites of cell-cell contact and in migrating neurons.
score: 3.7986388, Journal of cell science, 2001, Jenkins, S M et. al.

Identification of the critical domains of the delta-opioid receptor involved in G protein coupling using site-specific synthetic peptides.
score: 3.7962834, Molecular pharmacology, 1996, Merkouris, M et. al.

Recognition of infected cells by natural killer cells
score: 3.7960099, Current Opinion in Immunology, 2004, Carayannopoulos, Leonidas N; Yokoyama, Wayne M

CIB1 is an endogenous inhibitor of agonist-induced integrin αIIbβ3 activation
score: 3.7957183, The Journal of Cell Biology, 2006, Yuan, Weiping et. al.

Activation of ternary complex factor Elk-1 by stress-activated protein kinases
score: 3.7954981, Current Biology, 1995, Gille, Hendrik; Strahl, Thomas; Shaw, Peter E.

Regulation of Megakaryocytopoiesis and Platelet Production by Tyrosine Kinases and Tyrosine Phosphatases
score: 3.7938878, Methods, 1999, Avraham, Hava; Price, Daniel J.

BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II.
score: 3.79304, Oncogene, 2004, Cabart, Pavel; Chew, Helen K; Murphy, Shona

Mast cell signal transduction from the high-affinity IgE receptor
score: 3.7922772, Current Opinion in Immunology, 2003, Siraganian, Reuben P

Ubiquitin-mediated regulation of TNFR1 signaling
score: 3.792196, Cytokine and Growth Factor Reviews, 2008, Wertz, Ingrid E.; Dixit, Vishva M.

Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-γ1 complexed with a high affinity binding peptide
score: 3.7919205, Cell, 1994, Pascal, Steven M. et. al.

Feeling manipulated: cytomegalovirus immune manipulation
score: 3.7917395, Virology Journal, 2009, Miller-Kittrell, Mindy; Sparer, Tim E

The Nck family of adapter proteins
score: 3.7914882, Cellular Signalling, 2002, Buday, László; Wunderlich, Livius; Tamás, Peter

Cargo Selection by the COPII Budding Machinery during Export from the ER
score: 3.7913473, The Journal of Cell Biology, 1998, Aridor, Meir et. al.

Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking site for SH2-domain mediated interactions.
score: 3.7903208, Oncogene, 1998, Hock, B et. al.

Regulation of Endothelial Cell Motility by Complexes of Tetraspan Molecules CD81/TAPA-1 and CD151/PETA-3 with α3β1 Integrin Localized at Endothelial Lateral Junctions
score: 3.7896227, The Journal of Cell Biology, 1998, Yáñez-Mó, María et. al.

Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COS phox cells
score: 3.7894863, Cellular Signalling, 2010, Nie, Baoming; Cheng, Ni; Dinauer, Mary C.; Ye, Richard D.

IRAK-M Is a Negative Regulator of Toll-like Receptor Signaling
score: 3.7885248, Cell, 2002, Kobayashi, Koichi et. al.

Many faces of Ras activation
score: 3.7883275, BBA - Reviews on Cancer, 2008, Buday, László; Downward, Julian

p185c-neu and epidermal growth factor receptor associate into a structure composed of activated kinases.
score: 3.7877173, Proceedings of the National Academy of Sciences of the United States of America, 1992, Quian, X L; Decker, S J; Greene, M I

Identification and characterization of murine IRAK-2
score: 3.7874511, Biochemical and Biophysical Research Communications, 2002, Rosati, Olaf; Martin, Michael U

Non-synaptic ion channels in insects — basic properties of currents and their modulation in neurons and skeletal muscles
score: 3.7865929, Progress in Neurobiology, 2001, Wicher, Dieter; Walther, Christian; Wicher, Carola

The 3BP2 adapter protein is required for chemoattractant-mediated neutrophil activation.
score: 3.7825508, Journal of immunology (Baltimore, Md. : 1950), 2012, Chen, Grace et. al.

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family
score: 3.7823257, Cell, 1993, Suda, Takashi et. al.

Activation of the high-affinity immunoglobulin E receptor Fc epsilon RI in RBL-2H3 cells is inhibited by Syk SH2 domains.
score: 3.7817056, Molecular and cellular biology, 1995, Taylor, J A et. al.

A requirement for CD45 distinguishes Ly49D-mediated cytokine and chemokine production from killing in primary natural killer cells
score: 3.7803062, The Journal of Experimental Medicine, 2005, Huntington, Nicholas D. et. al.

Natural killer cells in non-hematopoietic malignancies
score: 3.7798817, Frontiers in Immunology, 2012, Desbois, Mélanie et. al.

Expression cloning of a cDNA encoding the murine interleukin 4 receptor based on ligand binding.
score: 3.7797431, Proceedings of the National Academy of Sciences of the United States of America, 1990, Harada, N et. al.

Platelet-derived growth factor in autocrine transformation.
score: 3.7786657, Cancer research, 1991, Westermark, B; Heldin, C H

Calcineurin negatively regulates TLR-mediated activation pathways.
score: 3.7784219, Journal of immunology (Baltimore, Md. : 1950), 2007, Kang, Young Jun et. al.

Distinct ligand binding sites in integrin α3β1 regulate matrix adhesion and cell–cell contact
score: 3.7778954, The Journal of Cell Biology, 2003, Zhang, Feng et. al.

Drosophila Dscam Is an Axon Guidance Receptor Exhibiting Extraordinary Molecular Diversity
score: 3.7778817, Cell, 2000, Schmucker, Dietmar et. al.

Posttranscriptional Mechanisms Regulating the Inflammatory Response
score: 3.7766443, Advances in Immunology, 2006, Stoecklin, Georg; Anderson, Paul

Posttranscriptional Mechanisms Regulating the Inflammatory Response
score: 3.7766443, Advances in Immunology, 2006, Stoecklin, Georg; Anderson, Paul

Caspase-dependent cleavage and inactivation of the Vav1 proto-oncogene product during apoptosis prevents IL-2 transcription.
score: 3.7763945, Oncogene, 2000, Hofmann, T G; Hehner, S P; Dröge, W; Schmitz, M L

Membrane lipid microdomains and the role of PKC θ in T cell activation
score: 3.7749941, Seminars in Immunology, 2001, Bi, Kun; Altman, Amnon

Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes.
score: 3.7749186, Molecular and cellular biology, 2000, Spilianakis, C; Papamatheakis, J; Kretsovali, A

Structural Basis for Recruitment of the Adaptor Protein APS to the Activated Insulin Receptor
score: 3.7745947, Molecular Cell, 2003, Hu, Junjie et. al.

Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
score: 3.7745899, Molecular pharmacology, 1993, Monsma, F J; Shen, Y; Ward, R P; Hamblin, M W; Sibley, D R

Negative Role of RIG-I Serine 8 Phosphorylation in the Regulation of Interferon-β Production *
score: 3.7742857, The Journal of Biological Chemistry, 2010, Nistal-Villán, Estanislao et. al.

Identification of CMTM7 as a Transmembrane Linker of BLNK and the B-Cell Receptor
score: 3.7734345, PLoS ONE, 2012, Miyazaki, Atsuko et. al.

Cadherin-11 interacts with the FGF receptor and induces neurite outgrowth through associated downstream signalling
score: 3.7733278, Cellular Signalling, 2008, Boscher, Cécile; Mège, René-Marc

Steroid Hormone Receptors and Heat Shock Proteins
score: 3.7722487, Vitamins and Hormones, 1998, Gehring, Ulrich

The many faces of ITAMs
score: 3.7716119, Trends in Immunology, 2007, Underhill, David M.; Goodridge, Helen S.

AlphaMbeta2 (CD11b/CD18, Mac-1) integrin activation by a unique monoclonal antibody to alphaM I domain that is divalent cation-sensitive.
score: 3.7706638, Journal of leukocyte biology, 2000, Orchekowski, R P; Plescia, J; Altieri, D C; Bajt, M L

Antibodies that identify only the active conformation of G(i) family G protein alpha subunits.
score: 3.7701469, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Lane, J Robert et. al.

Biochemical analysis of p120/130: a protein-tyrosine kinase substrate restricted to T and myeloid cells.
score: 3.7690466, Journal of immunology (Baltimore, Md. : 1950), 1997, da Silva, A J et. al.

Constitutively active Src facilitates NGF-induced phosphorylation of TrkA and causes enhancement of the MAPK signaling in SK-N-MC cells
score: 3.7667988, FEBS Letters, 2004, Tsuruda, Akinori et. al.

Phosphorylation of Grb2-associated binder 2 on serine 623 by ERK MAPK regulates its association with the phosphatase SHP-2 and decreases STAT5 activation.
score: 3.7664608, Journal of immunology (Baltimore, Md. : 1950), 2004, Arnaud, Mary et. al.

p27Kip1 inhibition of GRB2-SOS formation can regulate Ras activation.
score: 3.766335, Molecular and cellular biology, 2003, Moeller, Stephanie J; Head, Elizabeth D; Sheaff, Robert J

Spatiotemporal control of cyclic AMP immunomodulation through the PKA–Csk inhibitory pathway is achieved by anchoring to an Ezrin–EBP50–PAG scaffold in effector T cells
score: 3.765131, FEBS Letters, 2010, Cornez, Isabelle; Taskén, Kjetil

Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination.
score: 3.7650224, The EMBO journal, 2004, Watanabe, Kenji et. al.

Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
score: 3.7649166, The EMBO journal, 1997, Zhang, Z et. al.

The ubiquitination code: a signalling problem
score: 3.7635592, Cell Division, 2007, Woelk, Tanja et. al.

The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells.
score: 3.7629832, The EMBO journal, 2008, Takeya, Ryu et. al.

The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy
score: 3.7623221, The Journal of Experimental Medicine, 1995,

Nucleocytoplasmic Shuttling of Smads 2, 3, and 4 Permits Sensing of TGF-β Receptor Activity
score: 3.7620377, Molecular Cell, 2002, Inman, Gareth J.; Nicolás, Francisco J.; Hill, Caroline S.

Nucleocytoplasmic Shuttling of Smads 2, 3, and 4 Permits Sensing of TGF-β Receptor Activity
score: 3.7620377, Molecular Cell, 2002, Inman, Gareth J.; Nicolás, Francisco J.; Hill, Caroline S.

Increased mitogenicity of an alphabeta heterodimeric PDGF receptor complex correlates with lack of RasGAP binding.
score: 3.760834, Oncogene, 1999, Ekman, S; Thuresson, E R; Heldin, C H; Rönnstrand, L

CRAF Autophosphorylation of Serine 621 Is Required to Prevent Its Proteasome-Mediated Degradation
score: 3.7601234, Molecular Cell, 2008, Noble, Catherine et. al.

Autophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo.
score: 3.7595762, The EMBO journal, 1999, Vanhaesebroeck, B et. al.

Pre-mRNA Splicing Imprints mRNA in the Nucleus with a Novel RNA-Binding Protein that Persists in the Cytoplasm
score: 3.7590894, Molecular Cell, 2000, Kataoka, Naoyuki et. al.

Activation of Syk protein tyrosine kinase through interaction with integrin β cytoplasmic domains
score: 3.7589514, Current Biology, 2001, Woodside, Darren G. et. al.

Activation of Syk protein tyrosine kinase through interaction with integrin β cytoplasmic domains
score: 3.7589514, Current Biology, 2001, Woodside, Darren G. et. al.

The Ubiquitin-Proteasome System of Saccharomyces cerevisiae.
score: 3.7579006, Genetics, 2012, Finley, Daniel et. al.

Platelet–endothelial cell adhesion molecule-1 modulates endothelial migration through its immunoreceptor tyrosine-based inhibitory motif
score: 3.7577713, Biochemical and Biophysical Research Communications, 2003, Gratzinger, Dita; Barreuther, Mark; Madri, Joseph A

Sequential mutations in the interleukin-3 (IL3)/granulocyte-macrophage colony-stimulating factor/IL5 receptor beta-subunit genes are necessary for the complete conversion to growth autonomy mediated by a truncated beta C subunit.
score: 3.7576395, Molecular and cellular biology, 1995, Hannemann, J et. al.

Mutations in the activation loop tyrosines of protein tyrosine kinase Syk abrogate intracellular signaling but not kinase activity.
score: 3.7569756, Journal of immunology (Baltimore, Md. : 1950), 1998, Zhang, J; Kimura, T; Siraganian, R P

Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226.
score: 3.7562932, Journal of immunology (Baltimore, Md. : 1950), 2012, Liu, Jun et. al.

The SH2 domain-containing inositol 5-phosphatase SHIP1 is recruited to the intracytoplasmic domain of human FcγRIIB and is mandatory for negative regulation of B cell activation
score: 3.7559995, Immunology Letters, 2006, Isnardi, Isabelle et. al.

ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking.
score: 3.7558054, Biology of the cell / under the auspices of the European Cell Biology Organization, 2011, Yoon, Hye-Young et. al.

Structural analysis of receptor tyrosine kinases
score: 3.7554088, Progress in Biophysics and Molecular Biology, 1999, Hubbard, Stevan R

CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex.
score: 3.7546819, Proceedings of the National Academy of Sciences of the United States of America, 2002, Dias, Dora C; Dolios, Georgia; Wang, Rong; Pan, Zhen-Qiang

Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D.
score: 3.7523016, Journal of immunology (Baltimore, Md. : 1950), 2004, Bacon, Louise et. al.

A potential role for the plasmin(ogen) system in the posttranslational cleavage of the neural cell adhesion molecule L1.
score: 3.7488341, Journal of cell science, 1999, Nayeem, N et. al.

Identification and characterization of murine caspase-14, a new member of the caspase family.
score: 3.748674, Cancer research, 1998, Ahmad, M et. al.

Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells.
score: 3.7484475, Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 2001, Blalock, W L et. al.

Anterograde flow of cargo across the golgi stack potentially mediated via bidirectional "percolating" COPI vesicles.
score: 3.7482354, Proceedings of the National Academy of Sciences of the United States of America, 2000, Orci, L et. al.

Expression systems
score: 3.7481473, Current Opinion in Biotechnology, 1992,

Interference of distinct invariant chain regions with superantigen contact area and antigenic peptide binding groove of HLA-DR.
score: 3.7471697, Journal of immunology (Baltimore, Md. : 1950), 1995, Vogt, A B et. al.

Cleavage of K-FGF produces a truncated molecule with increased biological activity and receptor binding affinity
score: 3.7469975, The Journal of Cell Biology, 1993,

The first and third intracellular loops together with the carboxy terminal tail of the delta-opioid receptor contribute toward functional interaction with Galpha16.
score: 3.7467068, Journal of neurochemistry, 2003, Chan, Anthony S L et. al.

The DNA damage-inducible UbL-UbA protein Ddi1 participates in Mec1-mediated degradation of Ho endonuclease.
score: 3.7464922, Molecular and cellular biology, 2005, Kaplun, Ludmila et. al.

Regulation of the Forkhead transcription factor AFX by Ral-dependent phosphorylation of threonines 447 and 451.
score: 3.7439845, Molecular and cellular biology, 2001, De Ruiter, N D; Burgering, B M; Bos, J L

Contribution of Src and Ras pathways in FGF-2 induced endothelial cell differentiation.
score: 3.7436223, Oncogene, 1999, Klint, P; Kanda, S; Kloog, Y; Claesson-Welsh, L

The alphaherpesvirus US3/ORF66 protein kinases direct phosphorylation of the nuclear matrix protein matrin 3.
score: 3.7433592, Journal of virology, 2011, Erazo, Angela et. al.

Much more than the sum of the parts: structures of the dual SH2 domains of ZAP-70 and Syp
score: 3.7427195, Chemistry & Biology, 1996, Cowburn, David

Aurora A, Meiosis and Mitosis
score: 3.7426967, Biology of the Cell, 2004, Crane, Richard et. al.

Phosphoproteins in Stress-Induced Disease
score: 3.7419963, Progress in Molecular Biology and Translational Science, 2012, Dalton, Lucy E. et. al.

Polycation-based nanoparticle delivery of RNAi therapeutics: Adverse effects and solutions
score: 3.7419855, Advanced Drug Delivery Reviews, 2012, Ballarín-González, Borja; Howard, Kenneth Alan

Polycation-based nanoparticle delivery of RNAi therapeutics: Adverse effects and solutions
score: 3.7419855, Advanced Drug Delivery Reviews, 2012, Ballarín-González, Borja; Howard, Kenneth Alan

Multiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factor 1 1 The work forms part of the MD thesis of J.W.
score: 3.7417171, FEBS Letters, 2001, Wenzel, Jennifer et. al.

Identification of the cytoplasmic regions of fibroblast growth factor (FGF) receptor 1 which play important roles in induction of neurite outgrowth in PC12 cells by FGF-1.
score: 3.7412252, Molecular and cellular biology, 1998, Lin, H Y et. al.

Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress.
score: 3.7398881, Molecular and cellular biology, 2007, Nadanaka, Satomi et. al.

Dual Fatty Acylation of p59 Fyn Is Required for Association with the T Cell Receptor ζ Chain through Phosphotyrosine–Src Homology Domain-2 Interactions
score: 3.7398729, The Journal of Cell Biology, 1999, Hof, Woutervan't; Resh, Marilyn D.

Vav1 Transduces T Cell Receptor Signals to the Activation of Phospholipase C-γ1 via Phosphoinositide 3-Kinase-dependent and -independent Pathways
score: 3.7397519, The Journal of Experimental Medicine, 2002, Reynolds, Lucinda F. et. al.

SOCS-1, -2, -3: selective targets and functions downstream of the prolactin receptor
score: 3.7396937, Molecular and Cellular Endocrinology, 1999, Tomic, S; Chughtai, N; Ali, S

Calpain 3 cleaves filamin C and regulates its ability to interact with gamma- and delta-sarcoglycans.
score: 3.7387703, Muscle & nerve, 2003, Guyon, Jeffrey R et. al.

Signal transduction by the cloned glucagon-like peptide-1 receptor: comparison with signaling by the endogenous receptors of beta cell lines.
score: 3.7365473, Molecular pharmacology, 1994, Widmann, C; Bürki, E; Dolci, W; Thorens, B

Intramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain.
score: 3.7359958, Molecular and cellular biology, 2007, DeBell, Karen et. al.

smg-7 is required for mRNA surveillance in Caenorhabditis elegans.
score: 3.7353901, Genetics, 1999, Cali, B M; Kuchma, S L; Latham, J; Anderson, P

Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region.
score: 3.7346879, Proceedings of the National Academy of Sciences of the United States of America, 1995, Park, I et. al.

Endocytosis and Intracellular Trafficking of Notch and Its Ligands
score: 3.7342852, Current Topics in Developmental Biology, 2010, Yamamoto, Shinya; Charng, Wu-Lin; Bellen, Hugo J.

A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways.
score: 3.7338159, The EMBO journal, 2000, Meyer, H H; Shorter, J G; Seemann, J; Pappin, D; Warren, G

MAPPIT analysis of early Toll-like receptor signalling events
score: 3.73203, Immunology Letters, 2008, Ulrichts, Peter; Tavernier, Jan

Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding? 1 1 Edited by M. F. Summers
score: 3.7318876, Journal of Molecular Biology, 2001, Atkins, Annette R et. al.

Urea-inducible Egr-1 transcription in renal inner medullary collecting duct (mIMCD3) cells is mediated by extracellular signal-regulated kinase activation.
score: 3.7314112, Proceedings of the National Academy of Sciences of the United States of America, 1996, Cohen, D M

Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophages.
score: 3.7308952, Journal of cell science, 2009, Dovas, Athanassios et. al.

ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner.
score: 3.7297337, Molecular and cellular biology, 1998, Olayioye, M A et. al.

Six X-linked agammaglobulinemia-causing missense mutations in the Src homology 2 domain of Bruton's tyrosine kinase: phosphotyrosine-binding and circular dichroism analysis.
score: 3.7296665, Journal of immunology (Baltimore, Md. : 1950), 2000, Mattsson, P T et. al.

MafB Is an Interaction Partner and Repressor of Ets-1 That Inhibits Erythroid Differentiation
score: 3.7295306, Cell, 1996, Sieweke, Michael H et. al.

DLG1/SAP97 modulates transforming growth factor α bioavailability
score: 3.7277244, BBA - Molecular Cell Research, 2009, Surena, Anne-Laure et. al.

Targeting Src homology 2 domain-containing tyrosine phosphatase (SHP-1) into lipid rafts inhibits CD3-induced T cell activation.
score: 3.7273253, Journal of immunology (Baltimore, Md. : 1950), 2001, Su, M W; Yu, C L; Burakoff, S J; Jin, Y J

The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation.
score: 3.7271194, Molecular and cellular biology, 1991, Naldini, L et. al.

Complex Complexes: Signaling at the TCR
score: 3.7266087, Immunity, 1996, Wange, Ronald L; Samelson, Lawrence E

Surface Antigens of Human Leukocytes
score: 3.7243, Advances in Immunology, 1991, Hořejší, V.

The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression.
score: 3.7240372, Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 2003, Cappellini, A et. al.

Chemotactic activation of Dictyostelium AGC-family kinases AKT and PKBR1 requires separate but coordinated functions of PDK1 and TORC2.
score: 3.7237371, Journal of cell science, 2010, Liao, Xin-Hua; Buggey, Jonathan; Kimmel, Alan R

The novel functions of ubiquitination in signaling
score: 3.7226569, Current Opinion in Cell Biology, 2004, Sun, Lijun; Chen, Zhijian J

Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.
score: 3.7222411, Molecular and cellular biology, 2002, Chadee, Deborah N; Yuasa, Takashi; Kyriakis, John M

Crystal Structure of Mouse H2-M
score: 3.72188, Immunity, 1998, Fremont, Daved H et. al.

Modulating vaccine responses with dendritic cells and Toll-like receptors.
score: 3.7206778, Immunological reviews, 2004, Pulendran, Bali

IL-1 signaling cascade in liver cells and the involvement of a soluble form of the IL-1 receptor accessory protein.
score: 3.7205192, Journal of immunology (Baltimore, Md. : 1950), 2000, Jensen, L E; Muzio, M; Mantovani, A; Whitehead, A S

Notch and wingless regulate expression of cuticle patterning genes.
score: 3.7201179, Molecular and cellular biology, 1999, Wesley, C S

The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory
score: 3.719888, Progress in Neurobiology, 2004, Wright, John W; Harding, Joseph W

Activin signaling as an emerging target for therapeutic interventions
score: 3.7194246, Cell Communication and Signaling : CCS, 2009, Tsuchida, Kunihiro et. al.

Heterochromatin links to centromeric protection by recruiting shugoshin.
score: 3.7168842, Nature, 2008, Yamagishi, Yuya et. al.

Activation of c-Jun N-terminal kinase and activator protein 1 by receptor activator of nuclear factor kappaB.
score: 3.7159055, Molecular pharmacology, 2000, Lee, Z H; Kwack, K; Kim, K K; Lee, S H; Kim, H H

Pattern recognition by TREM-2: binding of anionic ligands.
score: 3.7157605, Journal of immunology (Baltimore, Md. : 1950), 2003, Daws, Michael R et. al.

Molecular Competition for NKG2D
score: 3.7154806, Immunity, 2001, O'Callaghan, Christopher A et. al.

Recruitment and activation of PLCgamma1 in T cells: a new insight into old domains.
score: 3.7154106, The EMBO journal, 2006, Braiman, Alex et. al.

Signaling by IL-2 and related cytokines: JAKs, STATs, and relationship to immunodeficiency.
score: 3.7139817, Journal of leukocyte biology, 1996, Johnston, J A; Bacon, C M; Riedy, M C; O'Shea, J J

NAP-2: histone chaperone function and phosphorylation state through the cell cycle 1 1 Edited by T. Richmond
score: 3.7138428, Journal of Molecular Biology, 2000, Rodriguez, Pedro et. al.

Ubiquitin-like protein activation.
score: 3.7134993, Oncogene, 2004, Huang, Danny T et. al.

Requirement of TFIIH kinase subunit Mat1 for RNA Pol II C-terminal domain Ser5 phosphorylation, transcription and mRNA turnover
score: 3.7133315, Nucleic Acids Research, 2011, Helenius, Katja et. al.

Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine).
score: 3.713118, Oncogene, 2002, Sato, Saori; Fujita, Naoya; Tsuruo, Takashi

Metalloproteinases and their inhibitors in tumor angiogenesis.
score: 3.7128969, International journal of cancer. Journal international du cancer, 2005, Handsley, Madeleine M; Edwards, Dylan R

T cell antigen-receptor signal transduction
score: 3.7121228, Current Opinion in Immunology, 1999, van Leeuwen, Jeroen EM; Samelson, Lawrence E

The Interleukin 1 Receptor: Ligand Interactions and Signal Transduction
score: 3.7115483, Cytokine and Growth Factor Reviews, 1998, Auron, Philip E.

Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells.
score: 3.7102225, Journal of leukocyte biology, 2011, Jevnikar, Zala et. al.

Composition of transcription factor B-TFIID.
score: 3.7097511, Proceedings of the National Academy of Sciences of the United States of America, 1992, Timmers, H T; Meyers, R E; Sharp, P A

Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.
score: 3.7093204, The EMBO journal, 1999, Williams, B L et. al.

Genetic analysis of the Caenorhabditis elegans MAP kinase gene mpk-1.
score: 3.7090136, Genetics, 1998, Lackner, M R; Kim, S K

Notch signaling: Emerging molecular targets for cancer therapy
score: 3.7085683, Biochemical Pharmacology, 2010, Yin, Ling; Velazquez, Omaida C.; Liu, Zhao-Jun

Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase
score: 3.7065097, The Journal of Experimental Medicine, 1996,

The structure of Wntch signalling and the resolution of transition states in development
score: 3.7060517, Seminars in Cell and Developmental Biology, 2012, Muñoz Descalzo, Silvia; Martinez Arias, Alfonso

An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells
score: 3.7059187, The Journal of Cell Biology, 2001, Belgareh, Naïma et. al.

Structure and dual function of vascular endothelial growth factor receptor-1 (Flt-1)
score: 3.7058341, International Journal of Biochemistry and Cell Biology, 2001, Shibuya, Masabumi

Redox Regulation of Cellular Signalling
score: 3.7050795, Cellular Signalling, 1999, Kamata, Hideaki; Hirata, Hajime

Actin nucleators in the nucleus: an emerging theme.
score: 3.7047968, Journal of cell science, 2012, Weston, Louise; Coutts, Amanda S; La Thangue, Nicholas B

Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.
score: 3.7035231, Molecular and cellular biology, 2002, Booden, Michelle A; Siderovski, David P; Der, Channing J

Anchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD protein
score: 3.7023299, The Journal of Cell Biology, 1996,

The membrane form of the DNA repair protein Ku interacts at the cell surface with metalloproteinase 9.
score: 3.7021161, The EMBO journal, 2004, Monferran, Sylvie et. al.

Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads
score: 3.7003461, FEBS Letters, 2012, Dupont, Sirio; Inui, Masafumi; Newfeld, Stuart J.

Regulation of TGF−β signal transduction by mono- and deubiquitylation of Smads
score: 3.7003461, FEBS Letters, 2012, Dupont, Sirio; Inui, Masafumi; Newfeld, Stuart J.

Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads
score: 3.7003461, FEBS Letters, 2012, Dupont, Sirio; Inui, Masafumi; Newfeld, Stuart J.

Effect of redox balance alterations on cellular localization of LAT and downstream T-cell receptor signaling pathways.
score: 3.7000062, Molecular and cellular biology, 2002, Gringhuis, Sonja I et. al.

CD7-mediated regulation of integrin adhesiveness on human T cells involves tyrosine phosphorylation-dependent activation of phosphatidylinositol 3-kinase.
score: 3.699898, Journal of immunology (Baltimore, Md. : 1950), 1997, Chan, A S; Mobley, J L; Fields, G B; Shimizu, Y

Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors
score: 3.6997027, The Journal of Cell Biology, 2006, Kawashima, Toshiyuki et. al.

Brefeldin A causes a microtubule-mediated fusion of the trans-Golgi network and early endosomes
score: 3.699411, Cell, 1991, Wood, Salli A.; Park, John E.; Brown, William J.

Spk1, a new kinase from Saccharomyces cerevisiae, phosphorylates proteins on serine, threonine, and tyrosine.
score: 3.6987839, Molecular and cellular biology, 1991, Stern, D F; Zheng, P; Beidler, D R; Zerillo, C

Matrix metalloproteinase 9 (MMP-9/gelatinase B) proteolytically cleaves ICAM-1 and participates in tumor cell resistance to natural killer cell-mediated cytotoxicity.
score: 3.6981692, Oncogene, 2002, Fiore, Emilio et. al.

Ubiquitination of the bacterial inositol phosphatase, SopB, regulates its biological activity at the plasma membrane.
score: 3.6981126, Cellular microbiology, 2009, Knodler, Leigh A et. al.

Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases.
score: 3.6961505, Proceedings of the National Academy of Sciences of the United States of America, 1994, Corey, S J et. al.

Interaction of the conserved oligomeric Golgi complex with t-SNARE Syntaxin5a/Sed5 enhances intra-Golgi SNARE complex stability
score: 3.694086, The Journal of Cell Biology, 2007, Shestakova, Anna et. al.

CEA adhesion molecules: multifunctional proteins with signal-regulatory properties
score: 3.6934601, Current Opinion in Cell Biology, 1997, Öbrink, Björn

Proteomic snapshot of the EGF-induced ubiquitin network.
score: 3.6929109, Molecular systems biology, 2011, Argenzio, Elisabetta et. al.

The BCR gene encodes a novel serine/threonine kinase activity within a single exon
score: 3.6926768, Cell, 1991, Maru, Yoshiro; Witte, Owen N.

Jun kinase phosphorylates and regulates the DNA binding activity of an octamer binding protein, T-cell factor beta1.
score: 3.6923003, Molecular and cellular biology, 1999, Kasibhatla, S et. al.

Microtubule depolymerization inhibits transport of cathepsin D from the Golgi apparatus to lysosomes.
score: 3.6906535, Journal of cell science, 1990, Scheel, J; Matteoni, R; Ludwig, T; Hoflack, B; Kreis, T E

Hypoxia-mediated Na-K-ATPase degradation requires von Hippel Lindau protein.
score: 3.6905296, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Zhou, Guofei et. al.

Insulin receptor structural requirements for the formation of a ternary complex with IRS-1 and PI 3-kinase
score: 3.6903733, Molecular and Cellular Endocrinology, 1996, Wilden, Peter A.; Rovira, Ilsa; Broadway, Dale E.

Mechanistic analysis of PCNA poly-ubiquitylation by the ubiquitin protein ligases Rad18 and Rad5.
score: 3.6902565, The EMBO journal, 2009, Parker, Joanne L; Ulrich, Helle D

Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein).
score: 3.6901795, European journal of immunology, 2001, Pfrepper, K I et. al.

GTPase-activating proteins and their complexes
score: 3.6883247, Current Opinion in Structural Biology, 1998, Gamblin, Steven J; Smerdon, Stephen J

Regulation of β1-integrin-mediated cell adhesion by the CbI adaptor protein
score: 3.6882123, Current Biology, 1998, Zell, Traci et. al.

Therapeutic targeting of Toll-like receptors for inflammatory and infectious diseases
score: 3.6880729, Current Opinion in Pharmacology, 2003, O’Neill, Luke AJ

A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases
score: 3.687908, Progress in Nucleic Acid Research and Molecular Biology, 2002, Quilliam, Lawrence A; Rebhun, John F; Castro, Ariel F

No Life Without Death
score: 3.6872785, Advances in Cancer Research, 2007, Krammer, Peter H. et. al.

No Life Without Death
score: 3.6872785, Advances in Cancer Research, 2007, Krammer, Peter H. et. al.

The role of the ran GTPase in nuclear assembly and DNA replication: characterisation of the effects of Ran mutants.
score: 3.6868419, Journal of cell science, 1998, Hughes, M; Zhang, C; Avis, J M; Hutchison, C J; Clarke, P R

Jaks, Stats and the Immune System
score: 3.6867721, Immunobiology, 1997, Decker, Thomas; Meinke, Andreas

Peptide library screening for determination of SH2 or phosphotyrosine-binding domain sequences
score: 3.685637, Methods in Enzymology, 2001, Songyang, Zhou; Liu, Dan

Tyrosine phosphorylation of Grb14 by Tie2
score: 3.6853207, Cell Communication and Signaling : CCS, 2010, Sturk, Celina; Dumont, Daniel J

Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth
score: 3.6853191, The Journal of Cell Biology, 2005, Pante, Guido et. al.

Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression
score: 3.6838622, Seminars in Cell and Developmental Biology, 2005, Kietzmann, Thomas; Görlach, Agnes

Stimulator of IFN gene is critical for induction of IFN-beta during Chlamydia muridarum infection.
score: 3.6834186, Journal of immunology (Baltimore, Md. : 1950), 2010, Prantner, Daniel; Darville, Toni; Nagarajan, Uma M

Regulatory interaction of phosducin-like protein with the cytosolic chaperonin complex.
score: 3.6834153, Proceedings of the National Academy of Sciences of the United States of America, 2002, McLaughlin, Joseph N et. al.

Integrin-linked kinase--essential roles in physiology and cancer biology.
score: 3.6829448, Journal of cell science, 2008, McDonald, Paul C; Fielding, Andrew B; Dedhar, Shoukat

Mammalian GGAs act together to sort mannose 6-phosphate receptors
score: 3.680904, The Journal of Cell Biology, 2003, Ghosh, Pradipta et. al.

Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal.
score: 3.679282, Proceedings of the National Academy of Sciences of the United States of America, 1995, Ladbury, J E et. al.

Signal transduction by interleukin-12 and interleukin-2. A comparison and contrast.
score: 3.6792501, Annals of the New York Academy of Sciences, 1996, Bacon, C M; Cho, S S; O'Shea, J J

Toll-like receptors in health and disease: complex questions remain.
score: 3.6782474, Journal of immunology (Baltimore, Md. : 1950), 2003, Sabroe, Ian et. al.

Coordination of activating and inhibitory signals in natural killer cells
score: 3.6780971, Molecular Immunology, 2005, Chiesa, Sabrina et. al.

Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury
score: 3.6776339, The Journal of Experimental Medicine, 2012, Block, Helena et. al.

The Src homology 2 domain-containing leukocyte protein of 76-kDa adaptor links integrin ligation with p44/42 MAPK phosphorylation and podosome distribution in murine dendritic cells.
score: 3.6775857, Journal of immunology (Baltimore, Md. : 1950), 2006, Luckashenak, Nancy A et. al.

Talking to chromatin: post-translational modulation of polycomb group function
score: 3.6775241, Epigenetics & Chromatin, 2009, Niessen, Hanneke EC; Demmers, Jeroen A; Voncken, Jan Willem

Novel functions of proteins encoded by viral stress-inducible genes
score: 3.6775066, Pharmacology and Therapeutics, 2004, Sarkar, Saumendra N.; Sen, Ganes C.

Toll-like receptors are part of the innate immune defense system of sponges (demospongiae: Porifera).
score: 3.6766183, Molecular biology and evolution, 2007, Wiens, Matthias et. al.

The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation.
score: 3.6757338, Cancer research, 2008, Ambrogio, Chiara et. al.

Ephrin-B2 is a candidate ligand for the Eph receptor, EphB6
score: 3.6755252, FEBS Letters, 2000, Munthe, Else et. al.

Structure of the human activating natural cytotoxicity receptor NKp30 bound to its tumor cell ligand B7-H6
score: 3.6755001, The Journal of Experimental Medicine, 2011, Li, Yili; Wang, Qian; Mariuzza, Roy A.

Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes.
score: 3.6748754, The FEBS journal, 2009, Pridgeon, Julia W et. al.

Bibliography of the current world literature
score: 3.6748459, Current Opinion in Neurobiology, 1994,

Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)
score: 3.6745074, Current Biology, 1998, Dutil, Erica M.; Toker, Alex; Newton, Alexandra C.

Cic1, an adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4.
score: 3.6730886, The EMBO journal, 2001, Jäger, S; Strayle, J; Heinemeyer, W; Wolf, D H

TLR signaling.
score: 3.673026, Cell death and differentiation, 2006, Kawai, T; Akira, S

The NOD: a signaling module that regulates apoptosis and host defense against pathogens.
score: 3.6720068, Oncogene, 2001, Inohara, N; Nuñez, G

PI3K/Akt activity has variable cell-specific effects on expression of HIF target genes, CA9 and VEGF, in human cancer cell lines
score: 3.6716577, Cancer Letters, 2009, Shafee, Norazizah et. al.

Regulation of Vav Localization in Membrane Rafts by Adaptor Molecules Grb2 and BLNK
score: 3.6702165, Immunity, 2003, Johmura, Sachiko et. al.

E7 abolishes raf-induced arrest via mislocalization of p21(Cip1).
score: 3.6699952, Molecular and cellular biology, 2002, Westbrook, Thomas F et. al.

A novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5
score: 3.6693014, The Journal of Cell Biology, 2004, Akazawa, Hiroshi et. al.

Adhesion and signaling in axonal fasciculation
score: 3.6688251, Current Opinion in Neurobiology, 1998, Van Vactor, David

Notch signaling in T cell development
score: 3.6682195, Current Opinion in Immunology, 2000, Deftos, Michael L; Bevan, Michael J

Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.
score: 3.6679896, Molecular and cellular biology, 2000, Kelkar, N; Gupta, S; Dickens, M; Davis, R J

Regulation of cytoplasmic mRNA decay.
score: 3.6679315, Nature reviews. Genetics, 2012, Schoenberg, Daniel R; Maquat, Lynne E

MIP-T3 Is a Negative Regulator of Innate Type I IFN Response.
score: 3.6672304, Journal of immunology (Baltimore, Md. : 1950), 2011, Ng, Ming-Him James et. al.

Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA.
score: 3.6667072, The EMBO journal, 2004, Kovall, Rhett A; Hendrickson, Wayne A

Alternative splicing generates isoforms of the met receptor tyrosine kinase which undergo differential processing.
score: 3.6660211, Molecular and cellular biology, 1991, Rodrigues, G A; Naujokas, M A; Park, M

Cell growth control by G protein-coupled receptors: from signal transduction to signal integration.
score: 3.6659809, Oncogene, 1998, Gutkind, J S

Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays
score: 3.6647236, Molecular Systems Biology, 2009, Persaud, Avinash et. al.

The G-protein-coupled CCK2 receptor associates with phospholipase Cγ1
score: 3.6637145, FEBS Letters, 2004, Arnould, Marika et. al.

Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks.
score: 3.6604783, Oncogene, 2004, Pommier, Yves et. al.

HLA class I molecules regulate IFN-gamma production induced in NK cells by target cells, viral products, or immature dendritic cells through the inhibitory receptor ILT2/CD85j.
score: 3.6599967, Journal of immunology (Baltimore, Md. : 1950), 2008, Morel, Esther; Bellón, Teresa

Recent Progress on the Regulation of Apoptosis by Bcl-2 Family Members
score: 3.6594489, Advances in Immunology, 1998, Minn, Andy J. et. al.

Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay
score: 3.6592681, Nucleic Acids Research, 2007, Luke, Brian et. al.

Clathrin- and dynamin-dependent coated vesicle formation from isolated plasma membranes.
score: 3.6585412, Traffic (Copenhagen, Denmark), 2003, Miwako, Ishido; Schröter, Thomas; Schmid, Sandra L

Nuclear export of NF90 to stabilize IL-2 mRNA is mediated by AKT-dependent phosphorylation at Ser647 in response to CD28 costimulation.
score: 3.6579345, Journal of immunology (Baltimore, Md. : 1950), 2008, Pei, Yuan et. al.

The activation and physiological functions of the proprotein convertases
score: 3.6575655, International Journal of Biochemistry and Cell Biology, 2008, Seidah, Nabil G. et. al.

Kinetic analysis of peptide loading onto HLA-DR molecules mediated by HLA-DM.
score: 3.6571049, Proceedings of the National Academy of Sciences of the United States of America, 1996, Vogt, A B; Kropshofer, H; Moldenhauer, G; Hämmerling, G J

The histone chaperone TAF-I/SET/INHAT is required for transcription in vitro of chromatin templates.
score: 3.6570977, Molecular and cellular biology, 2005, Gamble, Matthew J et. al.

Bifurcation of Cell Migratory and Proliferative Signaling by the Adaptor Protein Shc
score: 3.6561884, The Journal of Cell Biology, 1999, Collins, Lila R. et. al.

Sorting by COP I-coated vesicles under interphase and mitotic conditions
score: 3.6558172, The Journal of Cell Biology, 1996,

Toll-like receptors as adjuvant receptors
score: 3.655506, BBA - Molecular Cell Research, 2002, Kaisho, Tsuneyasu; Akira, Shizuo

Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling.
score: 3.6549808, Proceedings of the National Academy of Sciences of the United States of America, 1995, Yamauchi, K; Milarski, K L; Saltiel, A R; Pessin, J E

Neuroprotective Actions of PIKE-L by Inhibition of SET Proteolytic Degradation by Asparagine Endopeptidase
score: 3.6542552, Molecular Cell, 2008, Liu, Zhixue et. al.

Aurora B Regulates MCAK at the Mitotic Centromere
score: 3.6541362, Developmental Cell, 2004, Andrews, Paul D et. al.

Activation of ErbB3-PI3-kinase pathway is correlated with malignant phenotypes of adenocarcinomas.
score: 3.6539897, Oncogene, 2003, Kobayashi, Michimoto et. al.

p49 3F12 kinase: A novel MAP kinase expressed in a subset of neurons in the human nervous system
score: 3.6538055, Neuron, 1995, Mohit, Abdi A; Martin, Joel H; Miller, Carol A

Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action.
score: 3.6518985, Clinical microbiology reviews, 1999, Cardenas, M E et. al.

TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway
score: 3.6511446, Immunity, 2008, Michallet, Marie-Cécile et. al.

Activation state-specific monoclonal antibody detects tyrosine phosphorylated p185neu/erbB-2 in a subset of human breast tumors overexpressing this receptor.
score: 3.6508864, Cancer research, 1995, DiGiovanna, M P; Stern, D F

Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors.
score: 3.6504448, Journal of cell science, 2004, Tanimizu, Naoki; Miyajima, Atsushi

Recognition of additional roles for immunoglobulin domains in immune function
score: 3.6502394, Seminars in Immunology, 2010, Cannon, John P. et. al.

PWWP Module of Human Hepatoma-derived Growth Factor Forms a Domain-swapped Dimer with Much Higher Affinity for Heparin
score: 3.6497222, Journal of Molecular Biology, 2007, Sue, Shih-Che et. al.

Formation of crystalloid endoplasmic reticulum in COS cells upon overexpression of microsomal aldehyde dehydrogenase by cDNA transfection.
score: 3.6490825, Journal of cell science, 1996, Yamamoto, A; Masaki, R; Tashiro, Y

Visualizing Smad1/4 signaling response to bone morphogenetic Protein-4 activation by FRET biosensors
score: 3.6486455, BBA - Molecular Cell Research, 2007, Gromova, Kira V. et. al.

Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule.
score: 3.6481208, Molecular cancer research : MCR, 2002, Tsujikawa, Kazutake et. al.

Emerging paradigms of integrin ligand binding and activation.
score: 3.6475058, Kidney international, 1997, Sugimori, T; Griffith, D L; Arnaout, M A

The AP-1 repressor, JDP2, is a bona fide substrate for the c-Jun N-terminal kinase
score: 3.6473416, FEBS Letters, 2001, Katz, Sigal; Heinrich, Ronit; Aronheim, Ami

Epithelial Cell Adhesion Molecule (Ep-CAM) Modulates Cell–Cell Interactions Mediated by Classic Cadherins
score: 3.6461775, The Journal of Cell Biology, 1997, Litvinov, Sergey V. et. al.

PDK1-dependent activation of atypical PKC leads to degradation of the p21 tumour modifier protein.
score: 3.6441104, The EMBO journal, 2002, Scott, Mary T; Ingram, Angela; Ball, Kathryn L

Structure and allosteric regulation of the alpha X beta 2 integrin I domain.
score: 3.643839, Proceedings of the National Academy of Sciences of the United States of America, 2003, Vorup-Jensen, Thomas et. al.

Site-specific ubiquitination determines lysosomal sorting and signal attenuation of the granulocyte colony-stimulating factor receptor.
score: 3.6437997, Traffic (Copenhagen, Denmark), 2009, Wölfler, Albert et. al.

Ubiquitin interactions of NZF zinc fingers.
score: 3.6426785, The EMBO journal, 2004, Alam, Steven L et. al.

NCAM-induced intracellular signaling revisited.
score: 3.6425252, Journal of neuroscience research, 2008, Ditlevsen, Dorte Kornerup et. al.

The Leukocyte Receptor Complex in Chicken Is Characterized by Massive Expansion and Diversification of Immunoglobulin-Like Loci
score: 3.6406993, PLoS Genetics, 2006, Laun, Katja et. al.

The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression.
score: 3.6393717, Journal of cell science, 1999, Wells, N J et. al.

Negative regulation of HIF-1α by an FBW7-mediated degradation pathway during hypoxia.
score: 3.6381171, Journal of cellular biochemistry, 2011, Cassavaugh, Jessica M et. al.

Leukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytes.
score: 3.6380755, Oncogene, 2001, Ma, W; Xia, C; Ling, P; Qiu, M; Luo, Y; Tan, T H; Liu, M

Complex roles of Stat1 in regulating gene expression.
score: 3.638022, Oncogene, 2000, Ramana, C V; Chatterjee-Kishore, M; Nguyen, H; Stark, G R

In Vivo–Activated Cd4 T Cells Upregulate Cxc Chemokine Receptor 5 and Reprogram Their Response to Lymphoid Chemokines
score: 3.6374243, The Journal of Experimental Medicine, 1999, Ansel, K. Mark et. al.

Role of calnexin in the glycan-independent quality control of proteolipid protein.
score: 3.6370916, The EMBO journal, 2003, Swanton, Eileithyia; High, Stephen; Woodman, Philip

Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2.
score: 3.6368172, Molecular and cellular biology, 1998, Romano, P R et. al.

CRM1-mediated Recycling of Snurportin 1 to the Cytoplasm
score: 3.6362397, The Journal of Cell Biology, 1999, Paraskeva, Efrosyni et. al.

Regulation of allergy by Fc receptors
score: 3.635126, Current Opinion in Immunology, 2005, Bruhns, Pierre; Frémont, Sophie; Daëron, Marc

Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation in intact Swiss 3T3 cells.
score: 3.6349328, Proceedings of the National Academy of Sciences of the United States of America, 1991, Zachary, I et. al.

Catalysis and regulation
score: 3.6348594, Current Opinion in Structural Biology, 1996,

Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails.
score: 3.634498, Journal of cell science, 2009, Legate, Kyle R; Fässler, Reinhard

Hemidesmosome Formation Is Initiated by the β4 Integrin Subunit, Requires Complex Formation of β4 and HD1/Plectin, and Involves a Direct Interaction between β4 and the Bullous Pemphigoid Antigen 180
score: 3.6343087, The Journal of Cell Biology, 1998, Schaapveld, Roel Q.J. et. al.

A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion.
score: 3.6342367, Molecular and cellular biology, 1996, Fujioka, Y et. al.

Processing, localization, and requirement of human separase for normal anaphase progression.
score: 3.6341069, Proceedings of the National Academy of Sciences of the United States of America, 2003, Chestukhin, Anton et. al.

P-body formation is a consequence, not the cause, of RNA-mediated gene silencing.
score: 3.6336768, Molecular and cellular biology, 2007, Eulalio, Ana et. al.

Characterization of a rat type 2 angiotensin II receptor stably expressed in 293 cells
score: 3.6329648, Molecular and Cellular Endocrinology, 1995, Mukoyama, Masashi et. al.

Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells.
score: 3.6328969, Journal of cell science, 2007, El-Sibai, Mirvat et. al.

Role of two adaptor molecules SLP-76 and LAT in the PI3K signaling pathway in activated T cells.
score: 3.6328671, Journal of immunology (Baltimore, Md. : 1950), 2011, Shim, Eun Kyung; Jung, Seung Hee; Lee, Jong Ran

Notch signaling patterns Drosophila mesodermal segments by regulating the bHLH transcription factor twist.
score: 3.632545, Development (Cambridge, England), 2004, Tapanes-Castillo, Alexis; Baylies, Mary K

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors.
score: 3.6325198, Pharmacological reviews, 2002, Virág, László; Szabó, Csaba

CD44: Structure, Function and Association with the Malignant Process
score: 3.6322161, Advances in Cancer Research, 1997, Naor, David; Sionov, Ronit Vogt; Ish-Shalom, Dvorah

Membranes and sorting
score: 3.6316765, Current Opinion in Cell Biology, 1994,

IκB Kinase {varepsilon} Phosphorylates TRAF2 To Promote Mammary Epithelial Cell Transformation.
score: 3.631071, Molecular and cellular biology, 2012, Shen, Rhine R et. al.

Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C
score: 3.6305116, The Journal of Experimental Medicine, 1996,

Modulation of TRAIL Signaling Complex
score: 3.6293353, Vitamins and Hormones, 2004, Hao, Chunhai et. al.

The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors.
score: 3.6292852, Molecular and cellular biology, 1995, Kim, L; Wong, T W

The adapter molecule Gab2 regulates Fc epsilon RI-mediated signal transduction in mast cells.
score: 3.6290566, Journal of immunology (Baltimore, Md. : 1950), 2002, Xie, Zhi-Hui; Ambudkar, Indu; Siraganian, Reuben P

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176.
score: 3.6287463, Proceedings of the National Academy of Sciences of the United States of America, 1998, Ling, L; Cao, Z; Goeddel, D V

Suppression of RhoG activity is mediated by a syndecan 4–synectin–RhoGDI1 complex and is reversed by PKCα in a Rac1 activation pathway
score: 3.6280548, The Journal of Cell Biology, 2009, Elfenbein, Arye et. al.

A Role for Presenilin-1 in Nuclear Accumulation of Ire1 Fragments and Induction of the Mammalian Unfolded Protein Response
score: 3.6262991, Cell, 1999, Niwa, Maho et. al.

PKC-ζ-associated CK2 participates in the turnover of free IκBα 1 1 Edited by M. Yaniv
score: 3.6257006, Journal of Molecular Biology, 2000, Bren, Gary D; Pennington, Kevin N; Paya, Carlos V

Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells.
score: 3.6245365, Molecular and cellular biology, 2006, Abtahian, Farhad et. al.

Cloning of two new splice variants of Siglec-10 and mapping of the interaction between Siglec-10 and SHP-1
score: 3.6242945, Biochemical and Biophysical Research Communications, 2002, Kitzig, Friederike et. al.

Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer.
score: 3.6240317, Molecular and cellular biology, 2000, Huang, W; Zhou, X; Lefebvre, V; de Crombrugghe, B

Identification and characterization of an R-Smad ortholog (SmSmad1B) from Schistosoma mansoni.
score: 3.6238125, The FEBS journal, 2007, Carlo, Joelle M et. al.

G protein regulation of MAPK networks.
score: 3.6235832, Oncogene, 2007, Goldsmith, Z G; Dhanasekaran, D N

Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling.
score: 3.6226237, Journal of cell science, 2002, Lawrenson, Isobel D et. al.

Evidence That β3 Integrin-Induced Rac Activation Involves the Calpain-Dependent Formation of Integrin Clusters That Are Distinct from the Focal Complexes and Focal Adhesions That Form as Rac and Rhoa Become Active
score: 3.6213579, The Journal of Cell Biology, 2000, Bialkowska, Katarzyna et. al.

Multiple Facets of the Modulation of Growth by cAMP
score: 3.6213274, Vitamins and Hormones, 1995, Roger, Pierre P. et. al.

Multiple Facets of the Modulation of Growth by cAMP
score: 3.6213274, Vitamins and Hormones, 1995, Roger, Pierre P. et. al.

FcγRIIb-mediated negative regulation of BCR signalling is associated with the recruitment of the MAPkinase-phosphatase, Pac-1, and the 3′-inositol phosphatase, PTEN
score: 3.6200129, Cellular Signalling, 2004, Brown, Kirsty S. et. al.

Accessory molecules for MHC class II peptide loading
score: 3.6199434, Current Opinion in Immunology, 2000, Busch, Robert et. al.

G protein beta gamma subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm).
score: 3.6197225, Proceedings of the National Academy of Sciences of the United States of America, 1999, Kiyono, M; Satoh, T; Kaziro, Y

Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule
score: 3.6163065, The Journal of Cell Biology, 1991,

Glycosyl phosphatidylinositol--anchored T-cadherin mediates calcium- dependent, homophilic cell adhesion
score: 3.6158833, The Journal of Cell Biology, 1992,

Roles of LAP2 Proteins in Nuclear Assembly and DNA Replication: Truncated LAP2β Proteins Alter Lamina Assembly, Envelope Formation, Nuclear Size, and DNA Replication Efficiency in Xenopus laevis Extracts
score: 3.6157394, The Journal of Cell Biology, 1999, Gant, Tracey Michele et. al.

Assembly of the immunological synapse for T cells and NK cells
score: 3.6146502, Trends in Immunology, 2002, Davis, Daniel M

Subversion of innate host antiviral strategies by the hepatitis C virus
score: 3.6136104, Archives of Biochemistry and Biophysics, 2007, Bode, Johannes G.; Brenndörfer, Erwin D.; Häussinger, Dieter

Killer cell Ig-like receptor-dependent signaling by Ig-like transcript 2 (ILT2/CD85j/LILRB1/LIR-1).
score: 3.61343, Journal of immunology (Baltimore, Md. : 1950), 2005, Kirwan, Sheryl E; Burshtyn, Deborah N

mRNA quality control: An ancient machinery recognizes and degrades mRNAs with nonsense codons
score: 3.6127262, FEBS Letters, 2007, Behm-Ansmant, Isabelle et. al.

Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver.
score: 3.6124332, Hepatology (Baltimore, Md.), 2003, Yeon, Jong Eun et. al.

Membrane proteins
score: 3.6123439, Current Opinion in Structural Biology, 1996,

Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases
score: 3.6112627, Current Biology, 1995, Mayer, Bruce J.; Hirai, Hisamaru; Sakai, Ryuichi

Additional Serine/Threonine Phosphorylation Reduces Binding Affinity but Preserves Interface Topography of Substrate Proteins to the c-Cbl TKB Domain
score: 3.6110125, PLoS ONE, 2010, Sun, Qingxiang et. al.

Pharmacology of Cell Adhesion Molecules of the Nervous System
score: 3.6104789, Current Neuropharmacology, 2007, Kiryushko, Darya; Bock, Elisabeth; Berezin, Vladimir

Developments in expression cloning
score: 3.609622, Current Opinion in Biotechnology, 1995, Seed, Brian

CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion
score: 3.6082428, The Journal of Cell Biology, 2006, Sanjuan, Miguel A. et. al.

CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.
score: 3.6081813, Molecular and cellular biology, 2006, Lo, Shih-Ching; Hannink, Mark

GBF1, a guanine nucleotide exchange factor for ADP-ribosylation factors, is localized to the cis-Golgi and involved in membrane association of the COPI coat.
score: 3.6067061, Traffic (Copenhagen, Denmark), 2002, Kawamoto, Kazumasa et. al.

Cooperative phosphorylation of FADD by Aur-A and Plk1 in response to taxol triggers both apoptotic and necrotic cell death.
score: 3.6065119, Cancer research, 2011, Jang, Moon-Sun; Lee, Su-Jin; Kang, Nam Sook; Kim, Eunhee

A kinase activity associated with simian virus 40 large T antigen phosphorylates upstream binding factor (UBF) and promotes formation of a stable initiation complex between UBF and SL1.
score: 3.6058252, Molecular and cellular biology, 1999, Zhai, W; Comai, L

The Intersectin 2 Adaptor Links Wiskott Aldrich Syndrome Protein (WASp)-mediated Actin Polymerization to T Cell Antigen Receptor Endocytosis
score: 3.6047441, The Journal of Experimental Medicine, 2001, McGavin, Mary K.H. et. al.

The Innate Antiviral Response: New Insights Into A Continuing Story
score: 3.6033109, Advances in Virus Research, 2006, Paun, Andrea; Pitha, Paula M.

Alternate interferon signaling pathways
score: 3.6030939, Pharmacology and Therapeutics, 2003, Kalvakolanu, Dhananjaya V.

Interaction of p59fyn kinase with the dynein light chain, Tctex-1, and colocalization during cytokinesis.
score: 3.6024869, Journal of immunology (Baltimore, Md. : 1950), 1998, Campbell, K S; Cooper, S; Dessing, M; Yates, S; Buder, A

p38-MAPK Signals Survival by Phosphorylation of Caspase-8 and Caspase-3 in Human Neutrophils
score: 3.6008114, The Journal of Experimental Medicine, 2004, Alvarado-Kristensson, Maria et. al.

Protein—nucleic acid interactions
score: 3.5993137, Current Opinion in Structural Biology, 1996,

Proteins that bind high-mannose sugars of the HIV envelope
score: 3.5989136, Progress in Biophysics and Molecular Biology, 2005, Botos, Istvan; Wlodawer, Alexander

WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells.
score: 3.5984106, Proceedings of the National Academy of Sciences of the United States of America, 2006, Anselmo, Anthony N et. al.

Transcriptional Regulator CTCF Controls Human Interleukin 1 Receptor-associated Kinase 2 Promoter
score: 3.5978831, Journal of Molecular Biology, 2005, Kuzmin, Igor et. al.

Novel antibody tags from the rat lysosomal protein RT1.DM for immunodetection of recombinant proteins
score: 3.5972429, Journal of Immunological Methods, 2005, Neumann, Jürgen

The control and facilitation of MHC class II antigen processing by the BCR
score: 3.5969982, Current Opinion in Immunology, 2001, Siemasko, Karyn; Clark, Marcus R

Down-Regulation of a Novel Actin-Binding Molecule, Skeletrophin, in Malignant Melanoma
score: 3.5964713, The American Journal of Pathology, 2003, Takeuchi, Tamotsu et. al.

Membrane permeability
score: 3.5962693, Current Opinion in Cell Biology, 1996,

Extracellular ubiquitin: immune modulator and endogenous opponent of damage-associated molecular pattern molecules.
score: 3.5960817, Journal of leukocyte biology, 2011, Majetschak, Matthias

Signaling of apoptosis through TLRs critically involves toll/IL-1 receptor domain-containing adapter inducing IFN-beta, but not MyD88, in bacteria-infected murine macrophages.
score: 3.595864, Journal of immunology (Baltimore, Md. : 1950), 2004, Ruckdeschel, Klaus et. al.

Isolation of Functional Golgi-derived Vesicles with a Possible Role in Retrograde Transport
score: 3.5941905, The Journal of Cell Biology, 1998, Love, Harold D. et. al.

Natural killer cell activation receptors in innate immunity to infection
score: 3.5932441, Microbes and Infection, 2002, Yokoyama, Wayne M; Scalzo, Anthony A

Stoichiometry and intracellular fate of TRIM-containing TCR complexes
score: 3.5931875, Cell Communication and Signaling : CCS, 2010, Swamy, Mahima et. al.

Coupled Motions in the SH2 and Kinase Domains of Csk Control Src Phosphorylation
score: 3.5920792, Journal of Molecular Biology, 2005, Wong, Lilly et. al.

Bub1 is essential for assembly of the functional inner centromere
score: 3.5915947, The Journal of Cell Biology, 2007, Boyarchuk, Yekaterina et. al.

Kinesin superfamily motor proteins and intracellular transport.
score: 3.5910029, Nature reviews. Molecular cell biology, 2009, Hirokawa, Nobutaka et. al.

Akt-Mediated Phosphorylation of the G Protein-Coupled Receptor EDG-1 Is Required for Endothelial Cell Chemotaxis
score: 3.5901013, Molecular Cell, 2001, Lee, Menq-Jer et. al.

Solution structure of the C-terminal SH2 domain of the human tyrosine kinase Syk complexed with a phosphotyrosine pentapeptide
score: 3.5898295, Structure, 1995, Narula, SS et. al.

Signal transduction and endocytosis: close encounters of many kinds.
score: 3.5897292, Nature reviews. Molecular cell biology, 2002, Sorkin, Alexander; Von Zastrow, Mark

Signaling networks regulating beta1 integrin-mediated adhesion of T lymphocytes to extracellular matrix.
score: 3.5897274, Journal of leukocyte biology, 2001, Woods, M L; Shimizu, Y

Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling.
score: 3.5895857, Molecular and cellular biology, 1995, Graus-Porta, D; Beerli, R R; Hynes, N E

A novel trafficking signal within the HLA-C cytoplasmic tail allows regulated expression upon differentiation of macrophages.
score: 3.589485, Journal of immunology (Baltimore, Md. : 1950), 2008, Schaefer, Malinda R et. al.

Notch and the Immune System
score: 3.5889319, Immunity, 2003, Maillard, Ivan; Adler, Scott H.; Pear, Warren S.

Plakoglobin and beta-catenin: protein interactions, regulation and biological roles.
score: 3.586487, Journal of cell science, 2000, Zhurinsky, J; Shtutman, M; Ben-Ze'ev, A

Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: new partners in TCR/CD28 signal integration
score: 3.5861755, Molecular Immunology, 2002, Bauer, Birgit; Baier, Gottfried

Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function.
score: 3.5859512, Molecular and cellular biology, 1996, Kong, G et. al.

Recruitment of Slp-76 to the Membrane and Glycolipid-Enriched Membrane Microdomains Replaces the Requirement for Linker for Activation of T Cells in T Cell Receptor Signaling
score: 3.5857177, The Journal of Experimental Medicine, 2000, Boerth, Nancy J. et. al.

Immunogenetics of HIV and HIV associated tuberculosis
score: 3.5856058, Tuberculosis, 2012, Raghavan, S.; Alagarasu, K.; Selvaraj, P.

Coordination of an Array of Signaling Proteins through Homo- and Heteromeric Interactions Between PDZ Domains and Target Proteins
score: 3.5851104, The Journal of Cell Biology, 1998, Xu, Xian-Zhong Shawn et. al.

Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B.
score: 3.5844981, Molecular and cellular biology, 2010, Li, Xuan Shirley et. al.

The T-cell receptor signalosome: a dynamic structure with expanding complexity
score: 3.584095, Current Opinion in Immunology, 2002, Werlen, Guy; Palmer, Ed

Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor.
score: 3.5825306, The EMBO journal, 2000, McBride, K M; McDonald, C; Reich, N C

Cdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A.
score: 3.581196, Molecular and cellular biology, 2004, Alexandrow, Mark G; Hamlin, Joyce L

Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.
score: 3.5810626, Proceedings of the National Academy of Sciences of the United States of America, 2002, Brower, Christopher S et. al.

Cdk-Inhibitory Activity and Stability of p27 Kip1 Are Directly Regulated by Oncogenic Tyrosine Kinases
score: 3.5808166, Cell, 2007, Grimmler, Matthias et. al.

The dominant negative effect of a kinase-defective insulin receptor on insulin-like growth factor-I-stimulated signaling in Rat-1 fibroblasts
score: 3.5805721, Metabolism, 1996, Takata, Yasumitsu et. al.

Expression, mutagenesis and kinetic analysis of recombinant K1E endosialidase to define the site of proteolytic processing and requirements for catalysis.
score: 3.5781618, Molecular microbiology, 2002, Leggate, Daniel R et. al.

Janus kinases: components of multiple signaling pathways.
score: 3.5765904, Oncogene, 2000, Rane, S G; Reddy, E P

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics.
score: 3.5756432, Journal of cell science, 2010, Harbour, Michael E et. al.

Genetic Organization of Polytene Chromosomes
score: 3.5748117, Advances in Genetics, 1999, Zhimulev, I.F.

Soluble form of Jagged1: unique product of epithelial keratinocytes and a regulator of keratinocyte differentiation.
score: 3.5733345, Journal of cellular biochemistry, 2004, Aho, Sirpa

Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: implications for HIF-1alpha gene therapy.
score: 3.5728349, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Hofer, T; Desbaillets, I; Höpfl, G; Gassmann, M; Wenger, R H

SLP-76 is recruited to CD22 and dephosphorylated by SHP-1, thereby regulating B cell receptor-induced c-Jun N-terminal kinase activation.
score: 3.5724081, European journal of immunology, 2005, Mizuno, Kazuya et. al.

Assembly of Post-Receptor Signaling Complexes for the Tumor Necrosis Factor Receptor Superfamily
score: 3.5706325, Advances in Protein Chemistry, 2004, Wu, Hao

Assembly of Post-Receptor Signaling Complexes for the Tumor Necrosis Factor Receptor Superfamily
score: 3.5706325, Advances in Protein Chemistry, 2004, Wu, Hao

Evidence that nervy, the Drosophila homolog of ETO/MTG8, promotes mechanosensory organ development by enhancing Notch signaling
score: 3.570189, Developmental Biology, 2005, Wildonger, Jill; Mann, Richard S.

Jak3 Is Associated with CD40 and Is Critical for CD40 Induction of Gene Expression in B Cells
score: 3.5698529, Immunity, 1997, Hanissian, Silva H; Geha, Raif S

The “A Disintegrin And Metalloprotease” (ADAM) family of sheddases: Physiological and cellular functions
score: 3.5695699, Seminars in Cell and Developmental Biology, 2009, Reiss, Karina; Saftig, Paul

Molecular mechanisms in B cell antigen receptor signaling
score: 3.5694917, Current Opinion in Immunology, 1997, Kurosaki, Tomohiro

Protein translocation into peroxisomes by ring-shaped import receptors
score: 3.569129, FEBS Letters, 2007, Stanley, Will A. et. al.

Integrin-mediated Activation of Focal Adhesion Kinase Is Required for Signaling to Jun NH 2 -terminal Kinase and Progression through the G1 Phase of the Cell Cycle
score: 3.5686081, The Journal of Cell Biology, 1999, Oktay, Maja et. al.

Role of the TFG N-terminus and coiled-coil domain in the transforming activity of the thyroid TRK-T3 oncogene.
score: 3.5685678, Oncogene, 1998, Greco, A et. al.

The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1.
score: 3.5671859, Molecular and cellular biology, 2006, Kliche, Stefanie et. al.

Serine/Threonine Phosphatases: Mechanism through Structure
score: 3.5662956, Cell, 2009, Shi, Yigong

Interactions within the ubiquitin pathway of Caenorhabditis elegans
score: 3.565945, Biochemical and Biophysical Research Communications, 2004, Gudgen, Michelle et. al.

Receptor tyrosine kinases in normal and malignant haematopoiesis
score: 3.5659297, Blood Reviews, 2003, Reilly, John T

Interleukin-2, Interleukin-15, and Their Roles in Human Natural Killer Cells
score: 3.5657146, Advances in Immunology, 2005, Becknell, Brian; Caligiuri, Michael A.

Interleukin-2, Interleukin-15, and Their Roles in Human Natural Killer Cells
score: 3.5657146, Advances in Immunology, 2005, Becknell, Brian; Caligiuri, Michael A.

A sequence motif conserved in diverse nuclear proteins identifies a protein interaction domain utilised for nuclear targeting by human TFIIS
score: 3.5655501, Nucleic Acids Research, 2006, Ling, Yan; Smith, Abigail J.; Morgan, Garry T.

GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits.
score: 3.5652009, Proceedings of the National Academy of Sciences of the United States of America, 1996, De Vries, L; Elenko, E; Hubler, L; Jones, T L; Farquhar, M G

Chromatin Organization in the Mammalian Nucleus
score: 3.5619601, International Review of Cytology, 2004, Gilbert, Nick; Gilchrist, Susan; Bickmore, Wendy A.

Chromatin Organization in the Mammalian Nucleus
score: 3.5619601, International Review of Cytology, 2004, Gilbert, Nick; Gilchrist, Susan; Bickmore, Wendy A.

Metastatic Lymph Node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancer.
score: 3.5612359, Oncogene, 2002, Degot, Sébastien et. al.

GLUT4 translocation: The last 200 nanometers
score: 3.5611435, Cellular Signalling, 2007, Watson, Robert T.; Pessin, Jeffrey E.

Characterization of TCR-induced phosphorylation of PKCθ in primary murine lymphocytes
score: 3.5609091, Molecular Immunology, 2004, Thebault, Sabine; Ochoa-Garay, Jorge

The Atypical Serine Proteases of the Complement System
score: 3.5605388, Advances in Immunology, 1998, Arlaud, Gérard J. et. al.

Adaptor Protein Self-Assembly Drives the Control of a Cullin-RING Ubiquitin Ligase
score: 3.5604195, Structure, 2012, Errington, Wesley J. et. al.

Adaptor Protein Self-Assembly Drives the Control of a Cullin-RING Ubiquitin Ligase
score: 3.5604195, Structure, 2012, Errington, Wesley J. et. al.

A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK.
score: 3.5599691, The EMBO journal, 1998, Yablonski, D; Kane, L P; Qian, D; Weiss, A

trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca 2+ Entry
score: 3.5592672, Cell, 1996, Zhu, Xi et. al.

Functions of fibroblast growth factors in vertebrate development
score: 3.5588176, Cytokine and Growth Factor Reviews, 1996, Goldfarb, Mitchell

Intracellular signalling molecules as immunohistochemical markers of normal and neoplastic human leucocytes in routine biopsy samples.
score: 3.5578349, British journal of haematology, 2004, Pozzobon, Michela et. al.

The integration of signaling by multiprotein complexes containing Raf kinases
score: 3.557691, BBA - Molecular Cell Research, 2007, Kyriakis, John M.

Biology of chemokine and classical chemoattractant receptors: differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells
score: 3.5576522, The Journal of Cell Biology, 1996,

Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules.
score: 3.5547474, Journal of cell science, 2003, Haberman, Yael et. al.

SorLA regulates the activity of lipoprotein lipase by intracellular trafficking.
score: 3.5538581, Journal of cell science, 2011, Klinger, Stine C et. al.

Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae
score: 3.5536599, BBA - Molecular and Cell Biology of Lipids, 2007, Strahl, Thomas; Thorner, Jeremy

Involvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyrene.
score: 3.5533329, Molecular and cellular biology, 2001, Yoshii, S et. al.

Mechanism of Mpk1 mitogen-activated protein kinase binding to the Swi4 transcription factor and its regulation by a novel caffeine-induced phosphorylation.
score: 3.5525076, Molecular and cellular biology, 2009, Truman, Andrew W; Kim, Ki-Young; Levin, David E

Increased responsiveness of hypoxic endothelial cells to FGF2 is mediated by HIF-1alpha-dependent regulation of enzymes involved in synthesis of heparan sulfate FGF2-binding sites.
score: 3.5523902, Journal of cell science, 2002, Li, Jian; Shworak, Nicholas W; Simons, Michael

Integrin Signalling in Neutrophils and Macrophages
score: 3.5522987, Cellular Signalling, 1999, Berton, Giorgio; Lowell, Clifford A

ROS receptor tyrosine kinase: a new potential target for anticancer drugs.
score: 3.5518822, Medicinal research reviews, 2010, El-Deeb, Ibrahim Mustafa; Yoo, Kyung Ho; Lee, So Ha

Coordinate regulation of translation by the PI 3-kinase and mTOR pathways
score: 3.5509969, Advances in Cancer Research, 2002, Martin, Kathleen A.; Blenis, John

Coordinate regulation of translation by the PI 3-kinase and mTOR pathways
score: 3.5509969, Advances in Cancer Research, 2002, Martin, Kathleen A.; Blenis, John

Production and characterization of the extracellular domain of recombinant human fibroblast growth factor receptor 4
score: 3.5509814, International Journal of Biochemistry and Cell Biology, 2000, Loo, Britt-Marie et. al.

Structural biology of HIV 1 1 Edited by P. E. Wright
score: 3.5504745, Journal of Molecular Biology, 1999, Turner, Brian G; Summers, Michael F

Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques
score: 3.5504345, Current Biology, 1996, Sawai, Earl T. et. al.

CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes.
score: 3.5498148, Cell death and differentiation, 2010, Sun, S-C

Chemokine-Induced Zap70 Kinase-Mediated Dissociation of the Vav1-Talin Complex Activates α4β1 Integrin for T Cell Adhesion
score: 3.5495783, Immunity, 2009, García-Bernal, David et. al.

Crystal Structure and Ligand Binding Properties of the D1D2 Region of the Inhibitory Receptor LIR-1 (ILT2)
score: 3.5494788, Immunity, 2000, Chapman, Tara L. et. al.

Neural cell adhesion molecules in activity-dependent development and synaptic plasticity
score: 3.5490133, Trends in Neurosciences, 1996, Fields, R.Douglas; Itoh, Kouichi

Neural cell adhesion molecules in activity-dependent development and synaptic plasticity
score: 3.5490133, Trends in Neurosciences, 1996, Fields, R.Douglas; Itoh, Kouichi

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling.
score: 3.5485926, Molecular and cellular biology, 2011, Miyashita, Moeko et. al.

14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif
score: 3.5481861, DNA Repair, 2012, Andersen, Sofie Dabros et. al.

Non-T cell activation linker regulates ERK activation in Helicobacter pylori-infected epithelial cells
score: 3.5479595, Cellular Signalling, 2010, Rieke, Cornelia et. al.

Signalling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal protein kinases (JNKS): evidence for a divergence of the ERKs and JNKs pathways induced by Ret.
score: 3.5475687, Oncogene, 1998, Chiariello, M et. al.

SH2 domain protein interaction and possibilities for pharmacological intervention
score: 3.5457471, Cellular Signalling, 1996, Beattie, J

B cell antigen receptor assembly and Syk activation in the S2 cell reconstitution system
score: 3.5410749, Immunology Letters, 2004, Wossning, Thomas; Reth, Michael

Diverse Signaling Pathways Activated by Growth Factor Receptors Induce Broadly Overlapping, Rather Than Independent, Sets of Genes
score: 3.5404339, Cell, 1999, Fambrough, Douglas et. al.

VASCULAR ENDOTHELIAL GROWTH FACTOR INDUCES PROTEIN KINASE C (PKC)-DEPENDENT Akt/PKB ACTIVATION AND PHOSPHATIDYLINOSITOL 3′-KINASE-MEDIATED PKCδ PHOSPHORYLATION: ROLE OF PKC IN ANGIOGENESIS
score: 3.5401642, Cell Biology International, 2002, Gliki, Georgia; Wheeler-Jones, Caroline; Zachary, Ian

Identification of mutations in CUL7 in 3-M syndrome.
score: 3.5390523, Nature genetics, 2005, Huber, Céline et. al.

Vpu-dependent block to incorporation of GaLV Env into lentiviral vectors
score: 3.5390366, Retrovirology, 2010, Christodoulopoulos, Ilias et. al.

Altered NK Cell Development and Enhanced NK Cell-Mediated Resistance to Mouse Cytomegalovirus in NKG2D-Deficient Mice
score: 3.5375584, Immunity, 2009, Zafirova, Biljana et. al.

Role of linkers in communication between protein modules
score: 3.5375497, Current Opinion in Chemical Biology, 2000, Gokhale, Rajesh S; Khosla, Chaitan

Activating and inhibitory Ly49 receptors modulate NK cell chemotaxis to CXC chemokine ligand (CXCL) 10 and CXCL12.
score: 3.5368472, Journal of immunology (Baltimore, Md. : 1950), 2003, Inngjerdingen, Marit; Rolstad, Bent; Ryan, James C

A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.
score: 3.5363139, The EMBO journal, 1999, Yagi, R; Chen, L F; Shigesada, K; Murakami, Y; Ito, Y

Syk-independent tyrosine phosphorylation and association of the protein tyrosine phosphatases SHP-1 and SHP-2 with the high affinity IgE receptor.
score: 3.5359941, Journal of immunology (Baltimore, Md. : 1950), 1997, Kimura, T et. al.

Toll-like receptors: cellular signal transducers for exogenous molecular patterns causing immune responses
score: 3.5335877, International Journal of Medical Microbiology, 2001, Kirschning, Carsten J.; Bauer, Stefan

Initiation of eukaryotic DNA replication: Regulation and mechanisms
score: 3.5328561, Progress in Nucleic Acid Research and Molecular Biology, 2002, Nasheuer, Heinz-Peter et. al.

Initiation of eukaryotic DNA replication: Regulation and mechanisms
score: 3.5328561, Progress in Nucleic Acid Research and Molecular Biology, 2002, Nasheuer, Heinz-Peter et. al.

Human NKG2F is expressed and can associate with DAP12
score: 3.5320449, Molecular Immunology, 2004, Kim, Dae-Ki et. al.

Human herpesvirus 6 open reading frame U12 encodes a functional beta-chemokine receptor.
score: 3.5318651, Journal of virology, 1998, Isegawa, Y; Ping, Z; Nakano, K; Sugimoto, N; Yamanishi, K

Human herpesvirus 7 open reading frame U12 encodes a functional beta-chemokine receptor.
score: 3.5318651, Journal of virology, 2003, Nakano, Kazushi et. al.

Cleavage of TRPM7 Releases the Kinase Domain from the Ion Channel and Regulates Its Participation in Fas-Induced Apoptosis
score: 3.5307811, Developmental Cell, 2012, Desai, Bimal N. et. al.

Phosphotyrosine recognition domains: the typical, the atypical and the versatile
score: 3.5289852, Cell Communication and Signaling : CCS, 2012, Kaneko, Tomonori et. al.

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro
score: 3.5286284, Current Biology, 1998, Alessi, Dario R. et. al.

Role of SHP-2 in fibroblast growth factor receptor-mediated suppression of myogenesis in C2C12 myoblasts.
score: 3.5282644, Molecular and cellular biology, 2002, Kontaridis, Maria I et. al.

Tyrosine kinase receptors as attractive targets of cancer therapy
score: 3.525965, Critical Reviews in Oncology and Hematology, 2004, Bennasroune, Amar et. al.

Regulation of antigen receptor signal transduction by protein tyrosine kinases
score: 3.5255664, Current Opinion in Immunology, 1996, Chan, Andrew C; Shaw, Andrey S

FGF signaling in the developing endochondral skeleton
score: 3.5254704, Cytokine and Growth Factor Reviews, 2005, Ornitz, David M.

Tyrosine phosphorylation of G protein alpha subunits by pp60c-src.
score: 3.5242145, Proceedings of the National Academy of Sciences of the United States of America, 1992, Hausdorff, W P et. al.

New paradigms for the treatment of cancer: The role of anti-angiogenesis agents
score: 3.5239723, Advances in Cancer Research, 2000, Cherrington, Julie M.; Strawn, Laurie M.; Shawver, Laura K.

New paradigms for the treatment of cancer: The role of anti-angiogenesis agents
score: 3.5239723, Advances in Cancer Research, 2000, Cherrington, Julie M.; Strawn, Laurie M.; Shawver, Laura K.

Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain
score: 3.5237756, Cell, 2007, Wiesner, Silke et. al.

Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain.
score: 3.5223848, Proceedings of the National Academy of Sciences of the United States of America, 2000, Ozaki, K; Kikly, K; Michalovich, D; Young, P R; Leonard, W J

Epidermal growth factor regulates p21 ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor
score: 3.5223047, Cell, 1993, Buday, László; Downward, Julian

The Yersinia enterocolitica effector YopP inhibits host cell signalling by inactivating the protein kinase TAK1 in the IL-1 signalling pathway.
score: 3.5218944, EMBO reports, 2006, Thiefes, Axel et. al.

Evolution of domain families
score: 3.5218792, Advances in Protein Chemistry, 2000, Ponting, Chris P et. al.

The hydrophobic phosphorylation motif of conventional protein kinase C is regulated by autophosphorylation
score: 3.5215902, Current Biology, 1999, Behn-Krappa, Annett; Newton, Alexander C.

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
score: 3.5215537, Cell, 2010, Oh, Da Young et. al.

Notch signaling in glioblastoma: a developmental drug target?
score: 3.5203009, BMC Medicine, 2010, Lino, Maria Maddalena; Merlo, Adrian; Boulay, Jean-Louis

Human and rodent transcription elongation factor P-TEFb: interactions with human immunodeficiency virus type 1 tat and carboxy-terminal domain substrate.
score: 3.5199279, Journal of virology, 1999, Ramanathan, Y et. al.

Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases
score: 3.5194576, Current Biology, 1994, Strausfeld, Ulrich P. et. al.

The gatekeeper residue controls autoactivation of ERK2 via a pathway of intramolecular connectivity.
score: 3.5192493, Proceedings of the National Academy of Sciences of the United States of America, 2006, Emrick, Michelle A et. al.

γ-Interferon-regulated chaperone governs human lymphocyte antigen class II expression.
score: 3.5187464, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Kämper, Nadine et. al.

Integrin-associated protein (CD47) and its ligands
score: 3.5186705, Trends in Cell Biology, 2001, Brown, Eric J.; Frazier, William A.

The RAF proteins take centre stage.
score: 3.5184072, Nature reviews. Molecular cell biology, 2004, Wellbrock, Claudia; Karasarides, Maria; Marais, Richard

How epithelial cells detect danger: aiding the immune response.
score: 3.5181079, Allergy, 2008, Vroling, A B; Fokkens, W J; van Drunen, C M

Structure of an Hsp90-Cdc37-Cdk4 Complex
score: 3.5166584, Molecular Cell, 2006, Vaughan, Cara K. et. al.

Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains
score: 3.5166363, Structure, 2012, Liu, Shan et. al.

Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains
score: 3.5166363, Structure, 2012, Liu, Shan et. al.

Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: Disruption by hepatitis C virus NS3-4A protease
score: 3.5163611, Biochemical Pharmacology, 2006, Hiscott, John; Lacoste, Judith; Lin, Rongtuan

Neurosecretases provide strategies to treat sporadic and familial Alzheimer disorders
score: 3.5161498, Neurochemistry International, 2008, Marks, Neville; Berg, Martin J.

Integrin trafficking at a glance.
score: 3.5158205, Journal of cell science, 2012, Bridgewater, Rebecca E; Norman, Jim C; Caswell, Patrick T

SH2B1 Enhances Insulin Sensitivity by Both Stimulating the Insulin Receptor and Inhibiting Tyrosine Dephosphorylation of Insulin Receptor Substrate Proteins
score: 3.5157817, Diabetes, 2009, Morris, David L. et. al.

Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.
score: 3.5157505, Oncogene, 2005, Javelaud, Delphine; Mauviel, Alain

Gene expression of Sh3d19, a novel adaptor protein with five Src homology 3 domains, in anagen mouse hair follicles
score: 3.5149007, Journal of Dermatological Science, 2003, Shimomura, Yutaka; Aoki, Noriaki; Ito, Kaoru; Ito, Masaaki

Characterization of Vertebrate Cohesin Complexes and Their Regulation in Prophase
score: 3.5136154, The Journal of Cell Biology, 2000, Sumara, Izabela et. al.

PKC Phosphorylation of TRAF2 Mediates IKKα/β Recruitment and K63-Linked Polyubiquitination
score: 3.5129751, Molecular Cell, 2009, Li, Shitao; Wang, Lingyan; Dorf, Martin E.

Human Sec31B: a family of new mammalian orthologues of yeast Sec31p that associate with the COPII coat.
score: 3.5122314, Journal of cell science, 2006, Stankewich, Michael C; Stabach, Paul R; Morrow, Jon S

Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex
score: 3.5120461, Molecular Cell, 2009, Shi, Yongsheng et. al.

Synthetic Heparan Sulfate Oligosaccharides Inhibit Endothelial Cell Functions Essential for Angiogenesis
score: 3.5103553, PLoS ONE, 2010, Cole, Claire L. et. al.

Tumor Suppression by Phospholipase C-β3 via SHP-1-Mediated Dephosphorylation of Stat5
score: 3.5099951, Cancer Cell, 2009, Xiao, Wenbin et. al.

Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase.
score: 3.5097928, Oncogene, 2006, Avruch, J et. al.

Synaptic Accumulation of PSD-95 and Synaptic Function Regulated by Phosphorylation of Serine-295 of PSD-95
score: 3.5092767, Neuron, 2007, Kim, Myung Jong et. al.

LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation.
score: 3.508578, The EMBO journal, 2002, Nie, Jing et. al.

Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound.
score: 3.5082212, Journal of leukocyte biology, 2007, Loiarro, Maria et. al.

Primary structure and tissue distribution of two novel proline-rich gamma-carboxyglutamic acid proteins.
score: 3.5071247, Proceedings of the National Academy of Sciences of the United States of America, 1997, Kulman, J D; Harris, J E; Haldeman, B A; Davie, E W

Association of Wwox with ErbB4 in breast cancer.
score: 3.5069025, Cancer research, 2007, Aqeilan, Rami I et. al.

Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation.
score: 3.506071, Journal of immunology (Baltimore, Md. : 1950), 2000, Kawakami, Y et. al.

Proteolytic cleavage of the neural cell adhesion molecule by ADAM17/TACE is involved in neurite outgrowth.
score: 3.5025771, Journal of neurochemistry, 2006, Kalus, Ina et. al.

The ubiquitin code of yeast permease trafficking
score: 3.5021044, Trends in Cell Biology, 2010, Lauwers, Elsa et. al.

The Laminin–Nidogen Complex is a Ligand for a Specific Splice Isoform of the Transmembrane Protein Tyrosine Phosphatase LAR
score: 3.5000432, The Journal of Cell Biology, 1998, O'Grady, Pauline; Thai, Tran Cam; Saito, Haruo

Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis.
score: 3.4995544, Molecular and cellular biology, 2001, Bellosta, P et. al.

Genetic Analysis of Innate Immunity
score: 3.4986082, Advances in Immunology, 2006, Hoebe, Kasper et. al.

Genetic Analysis of Innate Immunity
score: 3.4986082, Advances in Immunology, 2006, Hoebe, Kasper et. al.

Alpha 4 beta 1 integrin-mediated tyrosine phosphorylation in human T cells: characterization of Crk- and Fyn-associated substrates (pp105, pp115, and human enhancer of filamentation-1) and integrin-dependent activation of p59fyn1.
score: 3.4984771, Journal of immunology (Baltimore, Md. : 1950), 1997, Hunter, A J; Shimizu, Y

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.
score: 3.49842, Proceedings of the National Academy of Sciences of the United States of America, 1996, van der Geer, P et. al.

From T-cell activation signals to signaling control of anti-cancer immunity.
score: 3.4970397, Immunological reviews, 2007, Cronin, Shane J F; Penninger, Josef M

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1.
score: 3.4949837, Molecular and cellular biology, 1993, Sun, X J et. al.

Kaposi's sarcoma-associated herpesvirus K3 utilizes the ubiquitin-proteasome system in routing class major histocompatibility complexes to late endocytic compartments.
score: 3.4948335, Journal of virology, 2002, Lorenzo, Mayra E; Jung, Jae U; Ploegh, Hidde L

PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor.
score: 3.4940159, Journal of biochemistry, 1997, Riedel, H; Wang, J; Hansen, H; Yousaf, N

Expression of Mona (monocytic adapter) in myeloid progenitor cells results in increased and prolonged MAP kinase activation upon macrophage colony-stimulating factor stimulation
score: 3.4936644, FEBS Letters, 2000, Bourgin, Caroline et. al.

Expansion of signal transduction by G proteins
score: 3.4934912, BBA - Biomembranes, 2007, Birnbaumer, Lutz

Ephrin-A1 induces c-Cbl phosphorylation and EphA receptor down-regulation in T cells.
score: 3.4921051, Journal of immunology (Baltimore, Md. : 1950), 2003, Sharfe, Nigel; Freywald, Andrew; Toro, Ana; Roifman, Chaim M

Agonist-dependent modulation of G protein-coupled receptor kinase 2 by mitogen-activated protein kinases.
score: 3.4903608, Molecular pharmacology, 2000, Elorza, A; Sarnago, S; Mayor, F

Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cδ in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration
score: 3.490139, Neuroscience, 2003, Kitazawa, M.; Anantharam, V.; Kanthasamy, A.G.

CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4.
score: 3.4883411, The EMBO journal, 2006, Slagsvold, Thomas et. al.

The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1
score: 3.4881701, Current Biology, 1998, Wu, Yongjian et. al.

commissureless Controls Growth Cone Guidance across the CNS Midline in Drosophila and Encodes a Novel Membrane Protein
score: 3.4877089, Neuron, 1996, Tear, Guy et. al.

Contribution of globular death domains and unstructured linkers to MyD88·IRAK-4 heterodimer formation: An explanation for the antagonistic activity of MyD88s
score: 3.4871498, Biochemical and Biophysical Research Communications, 2009, Mendoza-Barberá, Elena et. al.

microRNA expression in the eyes and their significance in relation to functions
score: 3.4867122, Progress in Retinal and Eye Research, 2009, Xu, Shunbin

The role of dendritic cells in the innate immune system
score: 3.4855232, Microbes and Infection, 2000, Clark, Georgina J et. al.

Toc64, a New Component of the Protein Translocon of Chloroplasts
score: 3.4843556, The Journal of Cell Biology, 2000, Sohrt, Karen; Soll, Jürgen

Moving away from the midline: new developments for Slit and Robo.
score: 3.4839519, Development (Cambridge, England), 2010, Ypsilanti, Athena R; Zagar, Yvrick; Chédotal, Alain

Poster Presentations
score: 3.4838831, British Journal of Cancer, 1998,

10th International Symposium on Biorecognition and Affinity Technology. Gwatt/Thun, Switzerland, October 1993. Abstracts.
score: 3.4833807, Journal of molecular recognition : JMR, 1993,

Par1b/MARK2 phosphorylates kinesin-like motor protein GAKIN/KIF13B to regulate axon formation.
score: 3.4828536, Molecular and cellular biology, 2010, Yoshimura, Yuta; Terabayashi, Takeshi; Miki, Hiroaki

The lymphocyte receptor CD6 interacts with syntenin-1, a scaffolding protein containing PDZ domains.
score: 3.4817435, Journal of immunology (Baltimore, Md. : 1950), 2005, Gimferrer, Idoia et. al.

Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays.
score: 3.481623, Molecular and cellular biology, 2006, Smith, Matthew J et. al.

Hem-1: Putting the “WAVE” into actin polymerization during an immune response
score: 3.4802582, FEBS Letters, 2010, Park, Heon; Chan, Maia M.; Iritani, Brian M.

Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen.
score: 3.4800668, Proceedings of the National Academy of Sciences of the United States of America, 1994, Campbell, K S et. al.

Ubiquitinylation of Ig beta dictates the endocytic fate of the B cell antigen receptor.
score: 3.4799382, Journal of immunology (Baltimore, Md. : 1950), 2007, Zhang, Miao et. al.

Trans-Synaptic Interaction of GluRδ2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum
score: 3.4797111, Cell, 2010, Uemura, Takeshi et. al.

Identification and characterization of an auto-activating MEK kinase from bovine brain: Phosphorylation of serine-298 in the proline-rich domain of the mammalian MEKs
score: 3.478961, International Journal of Biochemistry and Cell Biology, 1997, Wang, Jingxiong et. al.

The ubiquitin system, disease, and drug discovery
score: 3.4783636, BMC Biochemistry, 2008, Petroski, Matthew D

Cutting edge: NLRC5-dependent activation of the inflammasome.
score: 3.4783046, Journal of immunology (Baltimore, Md. : 1950), 2011, Davis, Beckley K et. al.

A Eukaryotic Translation Initiation Factor 4E-Binding Protein Promotes mRNA Decapping and Is Required for PUF Repression.
score: 3.4774133, Molecular and cellular biology, 2012, Blewett, Nathan H; Goldstrohm, Aaron C

Human Cytomegalovirus Glycoprotein UL16 Causes Intracellular Sequestration of NKG2D Ligands, Protecting Against Natural Killer Cell Cytotoxicity
score: 3.4770273, The Journal of Experimental Medicine, 2003, Dunn, Claire et. al.

Temporal Regulation of RNA Polymerase II by Srb10 and Kin28 Cyclin-Dependent Kinases
score: 3.4763371, Molecular Cell, 1998, Hengartner, Christoph J. et. al.

The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs.
score: 3.4756573, The FEBS journal, 2010, Athanasopoulos, Vicki et. al.

A Lumenal Domain-Dependent Pathway for Sorting to Intralumenal Vesicles of Multivesicular Endosomes Involved in Organelle Morphogenesis
score: 3.4747182, Developmental Cell, 2006, Theos, Alexander C. et. al.

The Indispensable N-Terminal Half of eIF3j/HCR1 Cooperates with its Structurally Conserved Binding Partner eIF3b/PRT1-RRM and with eIF1A in Stringent AUG Selection
score: 3.4745694, Journal of Molecular Biology, 2010, ElAntak, Latifa et. al.

Role of the LAT Adaptor in T‐Cell Development and T h2 Differentiation
score: 3.4744866, Advances in Immunology, 2005, Malissen, Bernard; Aguado, Enrique; Malissen, Marie

Role of the LAT Adaptor in T‐Cell Development and Th2 Differentiation
score: 3.4744866, Advances in Immunology, 2005, Malissen, Bernard; Aguado, Enrique; Malissen, Marie

Cooperative Inhibition of  T-Cell Antigen Receptor Signaling by a Complex between a Kinase and a Phosphatase
score: 3.4743804, The Journal of Experimental Medicine, 1999, Cloutier, Jean-François; Veillette, André

RPTP-α acts as a transducer of mechanical force on α v /β 3 -integrin–cytoskeleton linkages
score: 3.4742391, The Journal of Cell Biology, 2003, von Wichert, Götz et. al.

Characterisation and expression of a PP1 serine/threonine protein phosphatase (PfPP1) from the malaria parasite, Plasmodium falciparum: demonstration of its essential role using RNA interference
score: 3.4740984, Malaria Journal, 2002, Kumar, Rajinder et. al.

Uncoupling substrate and activation functions of rotavirus NSP5: phosphorylation of Ser-67 by casein kinase 1 is essential for hyperphosphorylation.
score: 3.4732989, Proceedings of the National Academy of Sciences of the United States of America, 2004, Eichwald, Catherine et. al.

MHC class I alleles and their exploration of the antigen-processing machinery.
score: 3.4730301, Immunological reviews, 2005, Groothuis, Tom A M et. al.

Microtubule-Associated Proteins and Their Essential Roles During Mitosis
score: 3.4726841, International Review of Cytology, 2004, Maiato, Hélder; Sampaio, Paula; Sunkel, Claudio E.

Microtubule-Associated Proteins and Their Essential Roles During Mitosis
score: 3.4726841, International Review of Cytology, 2004, Maiato, Hélder; Sampaio, Paula; Sunkel, Claudio E.

GRID: a novel Grb-2-related adapter protein that interacts with the activated T cell costimulatory receptor CD28.
score: 3.4722022, Journal of immunology (Baltimore, Md. : 1950), 2000, Ellis, J H et. al.

Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis
score: 3.4721972, Current Biology, 2001, Saxton, Tracy M et. al.

Inactivation of the checkpoint kinase Cds1 is dependent on cyclin B-Cdc2 kinase activation at the meiotic G(2)/M-phase transition in Xenopus oocytes.
score: 3.4721087, Journal of cell science, 2001, Gotoh, T; Ohsumi, K; Matsui, T; Takisawa, H; Kishimoto, T

The luminal domain of p23 (Tmp21) plays a critical role in p23 cell surface trafficking.
score: 3.4717514, Traffic (Copenhagen, Denmark), 2008, Blum, Robert; Lepier, Alexandra

c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene.
score: 3.4715278, Molecular and cellular biology, 2008, Wolter, Sabine et. al.

Differential effects of interleukin-2 and interleukin-4 on protein tyrosine phosphorylation in factor-dependent murine T cells
score: 3.4712211, BBA - Molecular Cell Research, 1990, Augustine, James A.; Schlager, Janis W.; Abraham, Robert T.

Mechanisms mediating caspase activation in cell death.
score: 3.4708424, Cell death and differentiation, 1999, Kumar, S

Signalling via integrins: Implications for cell survival and anticancer strategies
score: 3.4700677, BBA - Reviews on Cancer, 2007, Hehlgans, Stephanie; Haase, Michael; Cordes, Nils

Threonine 66 in the death domain of IRAK-1 is critical for interaction with signaling molecules but is not a target site for autophosphorylation.
score: 3.4700643, Journal of leukocyte biology, 2008, Neumann, Detlef et. al.

Inactivation of c-Cbl or Cbl-b differentially affects signaling from the high affinity IgE receptor.
score: 3.4699141, Journal of immunology (Baltimore, Md. : 1950), 2004, Zhang, Juan et. al.

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production
score: 3.4697308, The Journal of Experimental Medicine, 1996,

Rasd1 interacts with Ear2 (Nr2f6) to regulate renin transcription
score: 3.4697166, BMC Molecular Biology, 2011, Tan, Jen Jen; Ong, Shufen Angeline; Chen, Ken-Shiung

R-Ras Signals through Specific Integrin α Cytoplasmic Domains to Promote Migration and Invasion of Breast Epithelial Cells
score: 3.4693416, The Journal of Cell Biology, 1999, Keely, Patricia J. et. al.

A repertoire library that allows the selection of synthetic SH2s with altered binding specificities.
score: 3.4685252, Oncogene, 2001, Malabarba, M G et. al.

Ternary complex formation of EphA4, FGFR and FRS2alpha plays an important role in the proliferation of embryonic neural stem/progenitor cells.
score: 3.4680034, Genes to cells : devoted to molecular & cellular mechanisms, 2010, Sawada, Takahiro et. al.

The chemistry of oligosaccharide ligands of selectins: Significance for the development of new immunomodulatory medicines
score: 3.467945, Advances in Carbohydrate Chemistry and Biochemistry, 2001, Unger, Frank M.

A genetic screen to identify latent transforming growth factor β activators
score: 3.4665802, Analytical Biochemistry, 2004, Annes, Justin et. al.

Stepwise assembly of functionally active transport vesicles
score: 3.4658586, Cell, 1993, Ostermann, Joachim et. al.

Identification of human APC10/Doc1 as a subunit of anaphase promoting complex.
score: 3.4651063, Oncogene, 1999, Kurasawa, Y; Todokoro, K

Integration of the β-Catenin-Dependent Wnt Pathway with Integrin Signaling through the Adaptor Molecule Grb2
score: 3.4646909, PLoS ONE, 2009, Crampton, Steve P. et. al.

Ligand-induced clathrin-mediated endocytosis of the keratinocyte growth factor receptor occurs independently of either phosphorylation or recruitment of eps15
score: 3.4646313, FEBS Letters, 2003, Belleudi, Francesca et. al.

Selective in vivo recruitment of the phosphatidylinositol phosphatase SHIP by phosphorylated FcγRIIB during negative regulation of IgE-dependent mouse mast cell activation
score: 3.4636377, Immunology Letters, 1996, Fong, Dana C. et. al.

Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functions
score: 3.4627381, International Journal of Biochemistry and Cell Biology, 2000, Tumova, Sarka; Woods, Anne; Couchman, John R.

The cyclin D3-CDK4-p27 kip1 holoenzyme in thyroid epithelial cells: activation by TSH, inhibition by TGFβ, and phosphorylations of its subunits demonstrated by two-dimensional gel electrophoresis
score: 3.4626279, Experimental Cell Research, 2003, Coulonval, Katia et. al.

Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase
score: 3.4624915, Immunity, 1995, Kong, Guang-Hul et. al.

Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase
score: 3.4624915, Immunity, 1995, Kong, Guang-Hul et. al.

Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity.
score: 3.4623602, Proceedings of the National Academy of Sciences of the United States of America, 2005, Li, Xiao-Dong et. al.

HLA-F is a predominantly empty, intracellular, TAP-associated MHC class Ib protein with a restricted expression pattern.
score: 3.4616306, Journal of immunology (Baltimore, Md. : 1950), 2000, Wainwright, S D; Biro, P A; Holmes, C H

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins.
score: 3.4615496, Molecular and cellular biology, 1999, Movilla, N; Bustelo, X R

Dap10 and Dap12 Form Distinct, but Functionally Cooperative, Receptor Complexes in Natural Killer Cells
score: 3.4607834, The Journal of Experimental Medicine, 2000, Wu, Jun et. al.

SCAPER, a novel cyclin A–interacting protein that regulates cell cycle progression
score: 3.4585378, The Journal of Cell Biology, 2007, Tsang, William Y. et. al.

TNFalpha induces sequential activation of Cdc42- and p38/p53-dependent pathways that antagonistically regulate filopodia formation.
score: 3.4584839, Journal of cell science, 2004, Gadea, Gilles et. al.

Cooperation between Syk and Rac1 Leads to Synergistic JNK Activation in T Lymphocytes
score: 3.4576097, Immunity, 1998, Jacinto, Estela; Werlen, Guy; Karin, Michael

Differential phosphorylation controls Maskin association with eukaryotic translation initiation factor 4E and localization on the mitotic apparatus.
score: 3.4562833, Molecular and cellular biology, 2005, Barnard, Daron C; Cao, Quiping; Richter, Joel D

A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways.
score: 3.4552948, The EMBO journal, 1997, Takekawa, M; Posas, F; Saito, H

Hyperosmotic stress activates the insulin receptor in CHO cells
score: 3.4552401, BBA - Molecular Cell Research, 2001, Ouwens, D.Margriet et. al.

Characterization of agonist stimulation of cAMP-dependent protein kinase and G protein-coupled receptor kinase phosphorylation of the beta2-adrenergic receptor using phosphoserine-specific antibodies.
score: 3.4551834, Molecular pharmacology, 2004, Tran, Tuan M et. al.

CKI isoforms α and ε regulate Star–PAP target messages by controlling Star–PAP poly(A) polymerase activity and phosphoinositide stimulation
score: 3.454761, Nucleic Acids Research, 2011, Laishram, Rakesh S. et. al.

Identification and characterization of a novel human cDNA encoding a 21 kDa pRb-associated protein
score: 3.4542001, Gene, 2001, Wen, Hong; Ao, Shizhou

The Ran binding protein RanBPM interacts with Axl and Sky receptor tyrosine kinases
score: 3.454046, International Journal of Biochemistry and Cell Biology, 2005, Hafizi, Sassan et. al.

The nonintegrin laminin binding protein (p67 LBP) is expressed on a subset of activated human T lymphocytes and, together with the integrin very late activation antigen-6, mediates avid cellular adherence to laminin.
score: 3.4534726, Journal of immunology (Baltimore, Md. : 1950), 1999, Canfield, S M; Khakoo, A Y

Cleavage of a hydrophilic C-terminal domain increases growth-inhibitory activity of oncostatin M.
score: 3.4531809, Molecular and cellular biology, 1990, Linsley, P S; Kallestad, J; Ochs, V; Neubauer, M

The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma
score: 3.4528259, The Journal of Experimental Medicine, 2010, Pechloff, Konstanze et. al.

Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4.
score: 3.4528106, Journal of immunology (Baltimore, Md. : 1950), 2003, Doyle, Sean E et. al.

Human Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodies.
score: 3.452638, Molecular and cellular biology, 2010, Ozgur, Sevim; Chekulaeva, Marina; Stoecklin, Georg

A molecular view on signal transduction by the apoptosome
score: 3.4524948, Cellular Signalling, 2012, Reubold, Thomas F.; Eschenburg, Susanne

A molecular view on signal transduction by the apoptosome
score: 3.4524948, Cellular Signalling, 2012, Reubold, Thomas F.; Eschenburg, Susanne

Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development.
score: 3.452265, Journal of immunology (Baltimore, Md. : 1950), 2003, Zhu, Minghua; Janssen, Erin; Zhang, Weiguo

The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex.
score: 3.4522158, The EMBO journal, 1997, van Gool, A J et. al.

The role of Hsp90 in protein complex assembly
score: 3.4516146, BBA - Molecular Cell Research, 2012, Makhnevych, Taras; Houry, Walid A.

Induction of chondrocyte growth arrest by FGF: transcriptional and cytoskeletal alterations.
score: 3.4515615, Journal of cell science, 2002, Rozenblatt-Rosen, Orit et. al.

Basic FGF mediates an immediate response of articular cartilage to mechanical injury.
score: 3.4512776, Proceedings of the National Academy of Sciences of the United States of America, 2002, Vincent, Tonia et. al.

Removal of a Single Pore Subcomplex Results in Vertebrate Nuclei Devoid of Nuclear Pores
score: 3.4501732, Molecular Cell, 2003, Harel, Amnon et. al.

Endocytic events in TCR signaling: focus on adapters in microclusters.
score: 3.4501339, Immunological reviews, 2009, Balagopalan, Lakshmi; Barr, Valarie A; Samelson, Lawrence E

Tec Kinases in T Cell and Mast Cell Signaling
score: 3.4501301, Advances in Immunology, 2007, Felices, Martin; Falk, Markus; Kosaka, Yoko; Berg, Leslie J.

Tec Kinases in T Cell and Mast Cell Signaling
score: 3.4501301, Advances in Immunology, 2007, Felices, Martin; Falk, Markus; Kosaka, Yoko; Berg, Leslie J.

Association of the tyrosine kinase LCK with phospholipase C-gamma 1 after stimulation of the T cell antigen receptor
score: 3.4493242, The Journal of Experimental Medicine, 1992,

Structure and Function of Interleukin-1β Converting Enzyme
score: 3.4488359, Vitamins and Hormones, 1997, Tocci, Michael J.

What role(s) for TGFα in the central nervous system?
score: 3.4487983, Progress in Neurobiology, 2000, Junier, Marie-Pierre

Stimulation of fibroblast growth factor receptor-1 occupancy and signaling by cell surface-associated syndecans and glypican
score: 3.448468, The Journal of Cell Biology, 1996,

Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1
score: 3.4474486, Current Biology, 1998, Cohen, N.R. et. al.

Nonmuscle myosin-2: mix and match
score: 3.4465644, Cellular and Molecular Life Sciences, 2012, Heissler, Sarah M.; Manstein, Dietmar J.

Functional isoforms of IkappaB kinase alpha (IKKalpha) lacking leucine zipper and helix-loop-helix domains reveal that IKKalpha and IKKbeta have different activation requirements.
score: 3.4464139, Molecular and cellular biology, 2000, McKenzie, F R et. al.

How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-κB activation by members of the TNF/NGF receptor family
score: 3.4450507, Arthritis Research, 2002, Wallach, David et. al.

Isolation of baculovirus-expressed human vitamin D receptor: DNA responsive element interactions and phosphorylation of the purified receptor.
score: 3.444654, Journal of cellular biochemistry, 2002, Jurutka, Peter W et. al.

A Sos-derived peptidimer blocks the Ras signaling pathway by binding both Grb2 SH3 domains and displays antiproliferative activity.
score: 3.4442051, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Cussac, D et. al.

PRR5L degradation promotes MTORC2-mediated PKCδ phosphorylation and cell migration downstream of Gα12
score: 3.4439395, Nature Cell Biology, 2012, Gan, Xiaoqing et. al.

Down-regulation of integrin α M β 2 ligand-binding function by the urokinase-type plasminogen activator receptor
score: 3.4435731, Biochemical and Biophysical Research Communications, 2006, Tang, Man-Li; Kong, Le-Sheng; Law, S.K. Alex; Tan, Suet-Mien

Autoregulation and Homodimerization Are Involved in the Activation of the Plant Steroid Receptor BRI1
score: 3.4434719, Developmental Cell, 2005, Wang, Xuelu et. al.

Molecular biology of chronic myeloid leukemia.
score: 3.4432558, Cancer science, 2012, Maru, Yoshiro

The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo.
score: 3.4423817, Journal of cell science, 2012, Brachner, Andreas et. al.

The F-Box Protein Skp2 Participates in c-Myc Proteosomal Degradation and Acts as a Cofactor for c-Myc-Regulated Transcription
score: 3.4419522, Molecular Cell, 2003, von der Lehr, Natalie et. al.

Characterization of the SRP68/72 interface of human signal recognition particle by systematic site-directed mutagenesis.
score: 3.4413831, Protein science : a publication of the Protein Society, 2009, Iakhiaeva, Elena et. al.

G protein-coupled receptors and signaling pathways regulating growth responses.
score: 3.4409667, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1996, Post, G R; Brown, J H

Phosphorylation of HuR by Chk2 Regulates SIRT1 Expression
score: 3.4409582, Molecular Cell, 2007, Abdelmohsen, Kotb et. al.

Poliovirus-mediated disruption of cytoplasmic processing bodies.
score: 3.4403414, Journal of virology, 2011, Dougherty, Jonathan D; White, James P; Lloyd, Richard E

Regulation of Chk2 ubiquitination and signaling through autophosphorylation of serine 379.
score: 3.4400694, Molecular and cellular biology, 2008, Lovly, Christine M et. al.

Vav Family GEFs Link Activated Ephs to Endocytosis and Axon Guidance
score: 3.4383712, Neuron, 2005, Cowan, Christopher W. et. al.

Neutrophil adhesion and activation under flow.
score: 3.4372436, Microcirculation (New York, N.Y. : 1994), 2009, Zarbock, Alexander; Ley, Klaus

Molecular analysis of expression and function of hFcγRIIbl and b2 isoforms in myeloid cells
score: 3.4370239, Molecular Immunology, 2006, Joshi, Trupti et. al.

p21-activated kinase 4 interacts with integrin αvβ5 and regulates αvβ5-mediated cell migration
score: 3.4354578, The Journal of Cell Biology, 2002, Zhang, Hongquan et. al.

Syk-Mediated Translocation of PI3Kδ to the Leading Edge Controls Lamellipodium Formation and Migration of Leukocytes
score: 3.435372, PLoS ONE, 2007, Schymeinsky, Jürgen et. al.

Identification of a sequence that mediates promiscuous binding of invariant chain to MHC class II allotypes.
score: 3.4351159, Journal of immunology (Baltimore, Md. : 1950), 1998, Siebenkotten, I M; Carstens, C; Koch, N

Direct control of the Forkhead transcription factor AFX by protein kinase B.
score: 3.4340701, Nature, 1999, Kops, G J et. al.

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex.
score: 3.4332715, Proceedings of the National Academy of Sciences of the United States of America, 2002, Gao, Zhong-Hua et. al.

Interaction between the cytodomains of the alpha 3 and beta 1 integrin subunits regulates remodelling of adhesion complexes on laminin.
score: 3.4324278, Journal of cell science, 2000, Laplantine, E; Vallar, L; Mann, K; Kieffer, N; Aumailley, M

Phosphorylation on Thr-55 by TAF1 Mediates Degradation of p53
score: 3.4320418, Molecular Cell, 2004, Li, Heng-Hong; Li, Andrew G; Sheppard, Hilary M; Liu, Xuan

Transforming growth factor alpha: expression, regulation, and biological activities.
score: 3.4311493, Pharmacological reviews, 1995, Lee, D C; Fenton, S E; Berkowitz, E A; Hissong, M A

The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor.
score: 3.4306309, The FEBS journal, 2007, Bonaventure, Jacky et. al.

A comprehensive pathway map of epidermal growth factor receptor signaling
score: 3.4302792, Molecular Systems Biology, 2005, Oda, Kanae et. al.

The generation and function of soluble apoE receptors in the CNS
score: 3.4296261, Molecular Neurodegeneration, 2006, Rebeck, G William et. al.

Innate immunity to cytomegalovirus: the Cmv1 locus and its role in natural killer cell function
score: 3.4287841, Microbes and Infection, 2002, Lee, Seung-Hwan; Webb, John R.; Vidal, Silvia M.

Simultaneous induction of stimulatory and inhibitory signals by PDGF
score: 3.4284632, FEBS Letters, 1997, Heldin, Carl-Henrik

Simultaneous induction of stimulatory and inhibitory signals by PDGF
score: 3.4284632, FEBS Letters, 1997, Heldin, Carl-Henrik

The GIT-Associated Kinase PAK Targets to the Centrosome and Regulates Aurora-A
score: 3.428225, Molecular Cell, 2005, Zhao, Zhuo-shen et. al.

Synergy between suppressor of Hairless and Notch in regulation of Enhancer of split m gamma and m delta expression.
score: 3.427785, Molecular and cellular biology, 1997, Eastman, D S et. al.

Messenger RNA Turnover and its Regulation in Herpesviral Infection
score: 3.4276115, Advances in Virus Research, 2006, Glaunsinger, Britt A.; Ganem, Donald E.

Messenger RNA Turnover and its Regulation in Herpesviral Infection
score: 3.4276115, Advances in Virus Research, 2006, Glaunsinger, Britt A.; Ganem, Donald E.

T cell-specific adapter protein inhibits T cell activation by modulating Lck activity.
score: 3.4272675, Journal of immunology (Baltimore, Md. : 1950), 2000, Sundvold, V et. al.

Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2.
score: 3.4269912, The EMBO journal, 2006, Funakoshi-Tago, Megumi et. al.

GrinchGEF—A novel Rho-specific guanine nucleotide exchange factor
score: 3.4268233, Biochemical and Biophysical Research Communications, 2005, Winkler, Stefan et. al.

Pan1p, Yeast eps15, Functions as a Multivalent Adaptor That Coordinates Protein–Protein Interactions Essential for Endocytosis
score: 3.4262109, The Journal of Cell Biology, 1998, Wendland, Beverly; Emr, Scott D.

International union of pharmacology. XXII. Nomenclature for chemokine receptors.
score: 3.4257869, Pharmacological reviews, 2000, Murphy, P M et. al.

A novel N-terminal hydrophobic motif mediates constitutive degradation of serum- and glucocorticoid-induced kinase-1 by the ubiquitin-proteasome pathway.
score: 3.425416, The FEBS journal, 2006, Bogusz, Agata M et. al.

Monoubiquitination and endocytosis direct γ-secretase cleavage of activated Notch receptor
score: 3.4249908, The Journal of Cell Biology, 2004, Gupta-Rossi, Neetu et. al.

Formation of a carboxy-terminal domain phosphatase (Fcp1)/TFIIF/RNA polymerase II (pol II) complex in Schizosaccharomyces pombe involves direct interaction between Fcp1 and the Rpb4 subunit of pol II.
score: 3.424807, Molecular and cellular biology, 2002, Kimura, Makoto; Suzuki, Hisako; Ishihama, Akira

Cdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiation.
score: 3.424738, Molecular and cellular biology, 2009, Bae, Gyu-Un et. al.

Secretin and vasoactive intestinal peptide receptors: Members of a unique family of G protein–coupled receptors
score: 3.4236254, Gastroenterology, 1998, Ulrich, Charles D. et. al.

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.
score: 3.42345, Nature structural & molecular biology, 2007, Christensen, Devin E; Brzovic, Peter S; Klevit, Rachel E

DEVELOPMENTAL NEUROTOXICITY
score: 3.4229691, The Pediatric Clinics of North America, 2001, Bearer, Cynthia F.

Phosphotyrosine interactome of the ErbB-receptor kinase family
score: 3.4223486, Molecular Systems Biology, 2005, Schulze, Waltraud X; Deng, Lei; Mann, Matthias

Regulation of cyclin D2 and the cyclin D2 promoter by protein kinase A and CREB in lymphocytes.
score: 3.4215567, Oncogene, 2006, White, P C et. al.

Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton.
score: 3.4214427, Journal of immunology (Baltimore, Md. : 1950), 2005, Dombroski, Derek et. al.

The leukocyte cytoskeleton in cell migration and immune interactions
score: 3.4203717, International Review of Cytology, 2002, Vicente-Manzanares, Miguel et. al.

The leukocyte cytoskeleton in cell migration and immune interactions
score: 3.4203717, International Review of Cytology, 2002, Vicente-Manzanares, Miguel et. al.

The Syk tyrosine kinase: A new negative regulator in tumor growth and progression
score: 3.4200631, Cancer Letters, 2006, Coopman, Peter J.; Mueller, Susette C.

TPR Subunits of the Anaphase-Promoting Complex Mediate Binding to the Activator Protein CDH1
score: 3.4188793, Current Biology, 2003, Vodermaier, Hartmut C. et. al.

Epitope mapping of antibodies to the C-terminal region of the integrin beta 2 subunit reveals regions that become exposed upon receptor activation.
score: 3.4188599, Journal of immunology (Baltimore, Md. : 1950), 2001, Lu, C; Ferzly, M; Takagi, J; Springer, T A

Functional Interplay between Caspase Cleavage and Phosphorylation Sculpts the Apoptotic Proteome
score: 3.4186392, Cell, 2012, Dix, Melissa M. et. al.

Inhibition of Basal FGF Receptor Signaling by Dimeric Grb2
score: 3.4169863, Cell, 2012, Lin, Chi-Chuan et. al.

Cyclic AMP inhibits p38 activation via CREB-induced dynein light chain.
score: 3.4156436, Molecular and cellular biology, 2006, Zhang, Jiyan; Bui, Truc N; Xiang, Jialing; Lin, Anning

Anchoring junctions as drug targets: role in contraceptive development.
score: 3.4154694, Pharmacological reviews, 2008, Mruk, Dolores D; Silvestrini, Bruno; Cheng, C Yan

Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosis
score: 3.4151838, The Journal of Cell Biology, 2010, Bompard, Guillaume et. al.

Importin alpha associates with membranes and participates in nuclear envelope assembly in vitro.
score: 3.4148421, The EMBO journal, 2004, Hachet, Virginie et. al.

CDw78 defines MHC class II-peptide complexes that require Ii chain-dependent lysosomal trafficking, not localization to a specific tetraspanin membrane microdomain.
score: 3.4140454, Journal of immunology (Baltimore, Md. : 1950), 2006, Poloso, Neil J; Denzin, Lisa K; Roche, Paul A

The PI3K-Akt-mTOR pathway in initiation and progression of thyroid tumors
score: 3.4134349, Molecular and Cellular Endocrinology, 2010, Saji, Motoyasu; Ringel, Matthew D.

Role of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling
score: 3.4127908, Cellular Signalling, 2008, Caloca, María José et. al.

CpG oligonucleotides bind TLR9 and RRM-Containing proteins in Atlantic Salmon ( Salmo salar )
score: 3.4124003, BMC Immunology, 2013, Iliev, Dimitar B; Skjæveland, Ingrid; Jørgensen, Jorunn B

Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc.
score: 3.4117112, Molecular and cellular biology, 1998, Chen, W; Martindale, J L; Holbrook, N J; Liu, Y

Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters.
score: 3.4111703, Immunological reviews, 2009, Finetti, Francesca; Savino, Maria Teresa; Baldari, Cosima T

Endogenous opiates and behavior: 2011
score: 3.410621, Peptides, 2012, Bodnar, Richard J.

Endogenous opiates and behavior: 2011
score: 3.410621, Peptides, 2012, Bodnar, Richard J.

Expression of the Grb2-related protein of the lymphoid system in B cell subsets enhances B cell antigen receptor signaling through mitogen-activated protein kinase pathways.
score: 3.4095822, Journal of immunology (Baltimore, Md. : 1950), 2003, Yankee, Thomas M et. al.

p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15.
score: 3.4090983, Proceedings of the National Academy of Sciences of the United States of America, 1992, Parker, L L; Atherton-Fessler, S; Piwnica-Worms, H

Proteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability.
score: 3.4087745, Oncogene, 2011, Latonen, L; Moore, H M; Bai, B; Jäämaa, S; Laiho, M

DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.
score: 3.4076461, Molecular and cellular biology, 2005, Okamoto, Koji et. al.

Identification and Molecular Cloning of P75/Airm1, a Novel Member of the Sialoadhesin Family That Functions as an Inhibitory Receptor in Human Natural Killer Cells
score: 3.4071519, The Journal of Experimental Medicine, 1999, Falco, Michela et. al.

Rhodopsin and its kinase
score: 3.4056329, Methods in Enzymology, 2002, Sokal, Izabela et. al.

Sorting of MHC class II molecules into exosomes through a ubiquitin-independent pathway.
score: 3.4053964, Traffic (Copenhagen, Denmark), 2009, Gauvreau, Marie-Elaine et. al.

Regulation of FcεRI-mediated signaling by an adaptor protein STAP-2/BSK in rat basophilic leukemia RBL-2H3 cells
score: 3.4053237, Biochemical and Biophysical Research Communications, 2003, Yamamoto, Tetsuya et. al.

NMR structure of the first Ig module of mouse FGFR1.
score: 3.4053158, Protein science : a publication of the Protein Society, 2006, Kiselyov, Vladislav V et. al.

Cytokine-induced upregulation of NF-κB, IL-8, and ICAM-1 is dependent on colonic cell polarity: implication for PKCδ
score: 3.4052202, Experimental Cell Research, 2004, Vallee, Sebastien et. al.

Divalent cation regulation of the function of the leukocyte integrin LFA-1
score: 3.4042291, The Journal of Cell Biology, 1992,

Back to the Future with Ubiquitin
score: 3.404202, Cell, 2004, Pickart, Cecile M

Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis
score: 3.4038236, Developmental Cell, 2012, Desai, Bimal N. et. al.

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300
score: 3.4036722, Cell, 1997, Chen, Hongwu et. al.

Activation of Rac and tyrosine phosphorylation of cytokine receptors induced by cross-linking of integrin α4β1 and cell adhesion in hematopoietic cells
score: 3.4020687, Biochemical and Biophysical Research Communications, 2003, Kanda, Eiichiro et. al.

Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex
score: 3.4012351, The Journal of Experimental Medicine, 1995,

The VirD2 pilot protein of Agrobacterium-transferred DNA interacts with the TATA box-binding protein and a nuclear protein kinase in plants.
score: 3.4011005, Proceedings of the National Academy of Sciences of the United States of America, 2003, Bakó, László et. al.

Evidence for Bidentate Substrate Binding as the Basis for the K48 Linkage Specificity of Otubain 1
score: 3.4007373, Journal of Molecular Biology, 2009, Wang, Tao et. al.

soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling.
score: 3.4006926, Proceedings of the National Academy of Sciences of the United States of America, 1998, Selfors, L M; Schutzman, J L; Borland, C Z; Stern, M J

Stress granules and processing bodies are dynamically linked sites of mRNP remodeling
score: 3.3988144, The Journal of Cell Biology, 2005, Kedersha, Nancy et. al.

HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases.
score: 3.3974512, Journal of immunology (Baltimore, Md. : 1950), 1997, Suzuki, Y et. al.

Hedgehog Signal Transduction via Smoothened Association with a Cytoplasmic Complex Scaffolded by the Atypical Kinesin, Costal-2
score: 3.3972418, Molecular Cell, 2003, Lum, Lawrence et. al.

RanBP2 associates with Ubc9p and a modified form of RanGAP1.
score: 3.3966449, Proceedings of the National Academy of Sciences of the United States of America, 1997, Saitoh, H; Pu, R; Cavenagh, M; Dasso, M

HCMV pUS28 initiates pro-migratory signaling via activation of Pyk2 kinase
score: 3.3958946, Herpesviridae, 2010, Vomaske, Jennifer et. al.

Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding
score: 3.3958431, Molecular and Cellular Neuroscience, 2004, Liu, Zhe et. al.

Cyclin A2 Regulates Nuclear-Envelope Breakdown and the Nuclear Accumulation of Cyclin B1
score: 3.3942628, Current Biology, 2007, Gong, Delquin et. al.

Cell-matrix interactions in dermal repair and scarring
score: 3.3941758, Fibrogenesis & Tissue Repair, 2010, Eckes, Beate; Nischt, Roswitha; Krieg, Thomas

Controlling Destiny through Chemistry: Small-Molecule Regulators of Cell Fate
score: 3.393506, ACS Chemical Biology, 2009, Firestone, Ari J.; Chen, James K.

Identification of multiple SNT-binding sites on NPM-ALK oncoprotein and their involvement in cell transformation.
score: 3.3932968, Oncogene, 2007, Chikamori, M; Fujimoto, J; Tokai-Nishizumi, N; Yamamoto, T

Cross talk between beta-adrenergic and bradykinin B(2) receptors results in cooperative regulation of cyclic AMP accumulation and mitogen-activated protein kinase activity.
score: 3.3931837, Molecular and cellular biology, 2001, Hanke, S; Nürnberg, B; Groll, D H; Liebmann, C

The UV (Ribotoxic) stress response of human keratinocytes involves the unexpected uncoupling of the Ras-extracellular signal-regulated kinase signaling cascade from the activated epidermal growth factor receptor.
score: 3.3922544, Molecular and cellular biology, 2002, Iordanov, Mihail S et. al.

Ubiquitin and breast cancer.
score: 3.3904824, Oncogene, 2004, Ohta, Tomohiko; Fukuda, Mamoru

ITAM-based signaling beyond the adaptive immune response
score: 3.3900157, Immunology Letters, 2006, Fodor, Szabina; Jakus, Zoltán; Mócsai, Attila

Integrin associated proteins
score: 3.3882326, Current Opinion in Cell Biology, 1998, Hemler, Martin E

Ligand and p185c-neu density govern receptor interactions and tyrosine kinase activation.
score: 3.3879269, Proceedings of the National Academy of Sciences of the United States of America, 1994, Samanta, A; LeVea, C M; Dougall, W C; Qian, X; Greene, M I

Rac Mediates Cytoskeletal Rearrangements and Increased Cell Motility Induced by Urokinase-Type Plasminogen Activator Receptor Binding to Vitronectin
score: 3.387685, The Journal of Cell Biology, 2001, Kjøller, Lars; Hall, Alan

Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis.
score: 3.3860878, Journal of immunology (Baltimore, Md. : 1950), 1998, Zamorano, J; Keegan, A D

Cbl exposes its RING finger.
score: 3.3858198, Nature structural & molecular biology, 2012, Kales, Stephen C; Ryan, Philip E; Lipkowitz, Stanley

HLA-B44 polymorphisms at position 116 of the heavy chain influence TAP complex binding via an effect on peptide occupancy.
score: 3.3855448, Journal of immunology (Baltimore, Md. : 1950), 2006, Thammavongsa, Vilasack et. al.

The CAP-Gly Domain of CYLD Associates with the Proline-Rich Sequence in NEMO/IKKγ
score: 3.3853633, Structure, 2004, Saito, Kohei et. al.

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis
score: 3.384702, The Journal of Cell Biology, 2005, Sahlender, Daniela A. et. al.

Protein Kinase D1 and the β1 Integrin Cytoplasmic Domain Control β1 Integrin Function via Regulation of Rap1 Activation
score: 3.3841983, Immunity, 2005, Medeiros, Ricardo B. et. al.

PTMs in Conversation: Activity and Function of Deubiquitinating Enzymes Regulated via Post-Translational Modifications
score: 3.3841336, Cell Biochemistry and Biophysics, 2011, Kessler, Benedikt M.; Edelmann, Mariola J.

Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells
score: 3.3837396, Experimental Cell Research, 2008, Tamgüney, Tanja et. al.

Structural Evidence for a Sequential Release Mechanism for Activation of Heterotrimeric G Proteins
score: 3.3802767, Journal of Molecular Biology, 2009, Kapoor, Neeraj et. al.

Akt and 14-3-3 Control a PACS-2 Homeostatic Switch that Integrates Membrane Traffic with TRAIL-Induced Apoptosis
score: 3.3797089, Molecular Cell, 2009, Aslan, Joseph E. et. al.

MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity.
score: 3.3781207, Proceedings of the National Academy of Sciences of the United States of America, 1997, Li, Y; Gorbea, C; Mahaffey, D; Rechsteiner, M; Benezra, R

ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation.
score: 3.3780489, Oncogene, 2002, Morrison, Kevin B et. al.

Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction.
score: 3.3765801, Cancer research, 2009, Zhi, Gang et. al.

Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase *
score: 3.3750946, The Journal of Biological Chemistry, 2011, Jo, Youngah; Sguigna, Peter V.; DeBose-Boyd, Russell A.

Cbl Suppresses B Cell Receptor–Mediated Phospholipase C (Plc)-γ2 Activation by Regulating B Cell Linker Protein–Plc-γ2 Binding
score: 3.3736739, The Journal of Experimental Medicine, 2000, Yasuda, Tomoharu et. al.

Comparative study on the phosphotyrosine motifs of different cytokine receptors involved in STAT5 activation
score: 3.3730369, FEBS Letters, 1996, May, Petra et. al.

Activation of a nuclear Cdc2-related kinase within a mitogen-activated protein kinase-like TDY motif by autophosphorylation and cyclin-dependent protein kinase-activating kinase.
score: 3.3726519, Molecular and cellular biology, 2005, Fu, Zheng et. al.

Signaling network of the Btk family kinases.
score: 3.3725505, Oncogene, 2000, Qiu, Y; Kung, H J

The adaptor protein Gads (Grb2-related adaptor downstream of Shc) is implicated in coupling hemopoietic progenitor kinase-1 to the activated TCR.
score: 3.3722562, Journal of immunology (Baltimore, Md. : 1950), 2000, Liu, S K; Smith, C A; Arnold, R; Kiefer, F; McGlade, C J

The transmembrane adapter LAT plays a central role in immune receptor signalling.
score: 3.3715273, Oncogene, 2001, Wonerow, P; Watson, S P

The Syk Kinase SmTK4 of Schistosoma mansoni Is Involved in the Regulation of Spermatogenesis and Oogenesis
score: 3.3714314, PLoS Pathogens, 2010, Beckmann, Svenja et. al.

Active participation of endothelial cells in inflammation.
score: 3.3711957, Journal of leukocyte biology, 2005, Cook-Mills, Joan M; Deem, Tracy L

Differential effects of US2, US6 and US11 human cytomegalovirus proteins on HLA class Ia and HLA-E expression: impact on target susceptibility to NK cell subsets.
score: 3.3703473, European journal of immunology, 2003, Llano, Manuel et. al.

Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G.
score: 3.3699343, Proceedings of the National Academy of Sciences of the United States of America, 2003, Shiroishi, Mitsunori et. al.

Integrin Activation by Regulated Dimerization and Oligomerization of Platelet Endothelial Cell Adhesion Molecule (Pecam)-1 from within the Cell
score: 3.3689408, The Journal of Cell Biology, 2001, Zhao, Tieming; Newman, Peter J.

Sprouty2 down-regulation promotes axon growth by adult sensory neurons
score: 3.3683697, Molecular and Cellular Neuroscience, 2009, Hausott, Barbara et. al.

Self Protection from Anti-Viral Responses – Ro52 Promotes Degradation of the Transcription Factor IRF7 Downstream of the Viral Toll-Like Receptors
score: 3.3683082, PLoS ONE, 2010, Higgs, Rowan et. al.

Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation.
score: 3.3677633, Proceedings of the National Academy of Sciences of the United States of America, 2000, Baumann, B et. al.

Transcription repressor activity of spleen tyrosine kinase mediates breast tumor suppression.
score: 3.3672485, Cancer research, 2005, Wang, Lei et. al.

Early signaling pathways activated by c-Kit in hematopoietic cells
score: 3.3671187, International Journal of Biochemistry and Cell Biology, 1999, Linnekin, Diana

The Lyme disease spirochete Borrelia burgdorferi utilizes multiple ligands, including RNA, for interferon regulatory factor 3-dependent induction of type I interferon-responsive genes.
score: 3.3664287, Infection and immunity, 2010, Miller, Jennifer C et. al.

Ubiquitin-binding domains.
score: 3.3651812, Nature reviews. Molecular cell biology, 2005, Hicke, Linda; Schubert, Heidi L; Hill, Christopher P

Ubiquitylation and cell signaling.
score: 3.3645494, The EMBO journal, 2005, Haglund, Kaisa; Dikic, Ivan

Distinct sequence motifs within the cytoplasmic domain of the human IL-4 receptor differentially regulate apoptosis inhibition and cell growth.
score: 3.3644449, Journal of immunology (Baltimore, Md. : 1950), 1995, Deutsch, H H; Koettnitz, K; Chung, J; Kalthoff, F S

Structure of a Helically Extended SH3 Domain of the T Cell Adapter Protein ADAP
score: 3.3619428, Structure, 2004, Heuer, Katja et. al.

Regulation of angiogenesis by a small GTPase Rap1
score: 3.3617663, Vascular Pharmacology, 2010, Chrzanowska-Wodnicka, Magdalena

Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling.
score: 3.3616857, Molecular and cellular biology, 2003, Fujita, Fumitaka et. al.

CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?
score: 3.3611097, Current Opinion in Genetics & Development, 2002, Arias, Alfonso Martinez; Zecchini, Vincent; Brennan, Keith

Modulation of insulin-stimulated glycogen synthesis by Src Homology Phosphatase 2
score: 3.3606728, Molecular and Cellular Endocrinology, 2001, Ouwens, D.Margriet et. al.

Contents
score: 3.3597714, Current Opinion in Immunology, 1994,

Production and purification of functional truncated soluble forms of human recombinant L1 cell adhesion glycoprotein from Spodoptera frugiperda Sf9 cells
score: 3.359692, Protein Expression and Purification, 2007, Gouveia, Ricardo M. et. al.

Integrin CD11a cytoplasmic tail interacts with the CD45 membrane-proximal protein tyrosine phosphatase domain 1.
score: 3.3582874, Immunology, 2005, Geng, Xin; Tang, Ren-Hong; Law, S K Alex; Tan, Suet-Mien

HLA-B27 misfolding in transgenic rats is associated with activation of the unfolded protein response.
score: 3.3571482, Journal of immunology (Baltimore, Md. : 1950), 2005, Turner, Matthew J et. al.

Drosophila as a genetic and cellular model for studies on axonal growth
score: 3.3571141, Neural Development, 2007, Sánchez-Soriano, Natalia et. al.

Src homology 2-domain containing leukocyte-specific phosphoprotein of 76 kDa is mandatory for TCR-mediated inside-out signaling, but dispensable for CXCR4-mediated LFA-1 activation, adhesion, and migration of T cells.
score: 3.3569411, Journal of immunology (Baltimore, Md. : 1950), 2009, Horn, Jessica et. al.

Molecular cloning and functional characterization of a novel member of the C-C chemokine family.
score: 3.3566548, Journal of immunology (Baltimore, Md. : 1950), 1995, Hara, T et. al.

GEF-H1 Modulates Localized RhoA Activation during Cytokinesis under the Control of Mitotic Kinases
score: 3.3566049, Developmental Cell, 2007, Birkenfeld, Jörg et. al.

Subcellular localization of Toll-like receptor 3 in human dendritic cells.
score: 3.356596, Journal of immunology (Baltimore, Md. : 1950), 2003, Matsumoto, Misako et. al.

Neuroligin-1 induces neurite outgrowth through interaction with neurexin-1β and activation of fibroblast growth factor receptor-1.
score: 3.3562736, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Gjørlund, Michelle D et. al.

Cell transformation by fibroblast growth factors can be suppressed by truncated fibroblast growth factor receptors.
score: 3.3562228, Molecular and cellular biology, 1994, Li, Y; Basilico, C; Mansukhani, A

The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization.
score: 3.3561852, The EMBO journal, 2009, Berthouze, Magali et. al.

Regulating the Notch pathway in embryonic, adult and old stem cells
score: 3.3561584, Current Opinion in Pharmacology, 2007, Carlson, Morgan E; Conboy, Irina M

Host glycans and antigen presentation
score: 3.3555095, Microbes and Infection, 2012, Ryan, Sean O.; Cobb, Brian A.

Host glycans and antigen presentation
score: 3.3555095, Microbes and Infection, 2012, Ryan, Sean O.; Cobb, Brian A.

Host glycans and antigen presentation
score: 3.3555095, Microbes and Infection, 2012, Ryan, Sean O.; Cobb, Brian A.

Host glycans and antigen presentation
score: 3.3555095, Microbes and Infection, 2012, Ryan, Sean O.; Cobb, Brian A.

Innate immunogenetics: a tool for exploring new frontiers of host defence
score: 3.355131, The Lancet Infectious Diseases, 2007, Bochud, Pierre-Yves et. al.

Tec kinases regulate TCR-mediated recruitment of signaling molecules and integrin-dependent cell adhesion.
score: 3.3551215, Journal of immunology (Baltimore, Md. : 1950), 2005, Finkelstein, Lisa D; Shimizu, Yoji; Schwartzberg, Pamela L

Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein Tax
score: 3.354901, Cell & Bioscience, 2011, Wu, Xuefeng; Zhang, Minying; Sun, Shao-Cong

Regulation of cytotoxic T lymphocyte-associated molecule-4 by Src kinases.
score: 3.3548861, Journal of immunology (Baltimore, Md. : 1950), 1999, Chuang, E et. al.

Immunopurified small nucleolar ribonucleoprotein particles pseudouridylate rRNA independently of their association with phosphorylated Nopp140.
score: 3.354883, Molecular and cellular biology, 2002, Wang, Chen; Query, Charles C; Meier, U Thomas

Targeted expression of an oncogenic adaptor protein v-Crk potentiates axonal growth in dorsal root ganglia and motor neurons in vivo
score: 3.3539949, Developmental Brain Research, 1999, Weinstein, David E; Dobrenis, Kostantin; Birge, Raymond B

p37 Is a p97 Adaptor Required for Golgi and ER Biogenesis in Interphase and at the End of Mitosis
score: 3.3535426, Developmental Cell, 2006, Uchiyama, Keiji et. al.

Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37.
score: 3.3534142, Oncogene, 2003, Nony, Pascale et. al.

Inhibition of FGF receptor signalling in Xenopus oocytes: differential effect of Grb7, Grb10 and Grb14
score: 3.3513351, FEBS Letters, 2003, Cailliau, Katia et. al.

Casein kinase 2 associates with initiation-competent RNA polymerase I and has multiple roles in ribosomal DNA transcription.
score: 3.3513315, Molecular and cellular biology, 2006, Panova, Tatiana B et. al.

Integrating cell-signalling pathways with NF-kappaB and IKK function.
score: 3.3513147, Nature reviews. Molecular cell biology, 2007, Perkins, Neil D

The protein kinases of Caenorhabditis elegans: a model for signal transduction in multicellular organisms.
score: 3.3512546, Proceedings of the National Academy of Sciences of the United States of America, 1999, Plowman, G D; Sudarsanam, S; Bingham, J; Whyte, D; Hunter, T

Lipid rafts: resolution of the “fyn problem”?
score: 3.3511629, Molecular Immunology, 2004, Filipp, Dominik; Julius, Michael

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation.
score: 3.3507068, Molecular and cellular biology, 2003, Hu, Cheng-Jun et. al.

The clathrin adaptor complex 1 directly binds to a sorting signal in Ste13p to reduce the rate of its trafficking to the late endosome of yeast
score: 3.3502163, The Journal of Cell Biology, 2006, Foote, Christopher; Nothwehr, Steven F.

Emerging views on integrin signaling via Rac1 during invasin-promoted bacterial uptake
score: 3.3501501, Current Opinion in Microbiology, 2005, Wong, Ka-Wing; Isberg, Ralph R

Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha.
score: 3.3489704, The EMBO journal, 2002, McBride, Kevin M et. al.

TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA.
score: 3.3470811, The EMBO journal, 2007, Lee, Matt K et. al.

A filarial nematode-secreted phosphorylcholine-containing glycoprotein uncouples the B cell antigen receptor from extracellular signal-regulated kinase-mitogen-activated protein kinase by promoting the surface Ig-mediated recruitment of Src homology 2 domain-containing tyrosine phosphatase-1 and Pac-1 mitogen-activated kinase-phosphatase.
score: 3.3467083, Journal of immunology (Baltimore, Md. : 1950), 2001, Deehan, M R; Harnett, W; Harnett, M M

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles
score: 3.3466527, Cell, 1990, Copeland, Neal G. et. al.

SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.
score: 3.3464119, The EMBO journal, 2011, Cui, Yu et. al.

Identification and functional analysis of TopBP1 and its homologs
score: 3.3457504, DNA Repair, 2005, Garcia, Valerie; Furuya, Kanji; Carr, Antony M.

Distinct tyrosine phosphorylation sites in JAK3 kinase domain positively and negatively regulate its enzymatic activity.
score: 3.3453751, Proceedings of the National Academy of Sciences of the United States of America, 1997, Zhou, Y J et. al.

Functional interaction between Env oncogene from Jaagsiekte sheep retrovirus and tumor suppressor Sprouty2
score: 3.3450939, Retrovirology, 2010, Chitra, Ebenezer et. al.

Modularity and functional plasticity of scaffold proteins as p(l)acemakers in cell signaling
score: 3.3448708, Cellular Signalling, 2012, Pan, Catherine Qiurong et. al.

Molecular analyses of the interactions between human NK receptors and their HLA ligands
score: 3.3448426, Human Immunology, 2000, Valés-Gómez, Mar; Reyburn, Hugh; Strominger, Jack

XRHAMM Functions in Ran-Dependent Microtubule Nucleation and Pole Formation during Anastral Spindle Assembly
score: 3.3445621, Current Biology, 2004, Groen, Aaron C. et. al.

Cellular effects of phosphotyrosine-binding domain inhibitors on insulin receptor signaling and trafficking.
score: 3.3432602, Molecular and cellular biology, 1997, Giorgetti-Peraldi, S et. al.

Proteolytic processing of the adherens junctions components beta-catenin and gamma-catenin/plakoglobin during apoptosis.
score: 3.3426295, Cell death and differentiation, 1998, Brancolini, C; Sgorbissa, A; Schneider, C

Lbc proto-oncogene product binds to and could be negatively regulated by metastasis suppressor nm23-H2
score: 3.3422376, Biochemical and Biophysical Research Communications, 2004, Iwashita, Shinki et. al.

Structure of the TPR Domain of p67 phox in Complex with Rac·GTP
score: 3.3421298, Molecular Cell, 2000, Lapouge, Karine et. al.

The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IkappaB kinase family members.
score: 3.3418943, Journal of immunology (Baltimore, Md. : 1950), 2006, Zha, Jikun et. al.

Rac1 and PAK1 are upstream of IKK-ε and TBK-1 in the viral activation of interferon regulatory factor-3
score: 3.3418317, FEBS Letters, 2004, Ehrhardt, Christina et. al.

B cell antigen receptor-induced activation of an IRAK4-dependent signaling pathway revealed by a MALT1-IRAK4 double knockout mouse model
score: 3.3418168, Cell Communication and Signaling : CCS, 2011, Dufner, Almut; Schamel, Wolfgang W

Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness.
score: 3.3415609, Cancer research, 2009, Jin, Chaoyang et. al.

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation.
score: 3.3414067, Molecular and cellular biology, 1996, Khosravi-Far, R et. al.

RoXaN, a novel cellular protein containing TPR, LD, and zinc finger motifs, forms a ternary complex with eukaryotic initiation factor 4G and rotavirus NSP3.
score: 3.3413437, Journal of virology, 2004, Vitour, Damien et. al.

Selective expression of a novel surface molecule by human Th2 cells in vivo.
score: 3.3407794, Journal of immunology (Baltimore, Md. : 1950), 1999, Nagata, K et. al.

A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells
score: 3.3407551, Developmental Biology, 2009, Hansson, Mattias et. al.

Role of vasodilator-stimulated phosphoprotein in PKA-induced changes in endothelial junctional permeability.
score: 3.3399621, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Comerford, Katrina M et. al.

Identification and characterization of the murine homologue of CD22, a B lymphocyte-restricted adhesion molecule.
score: 3.3396938, Journal of immunology (Baltimore, Md. : 1950), 1992, Torres, R M et. al.

Detection and delineation of CXCR-4 (fusin) as an entry and fusion cofactor for T-tropic [correction of T cell-tropic] HIV-1 by three different monoclonal antibodies.
score: 3.3395775, Journal of immunology (Baltimore, Md. : 1950), 1998, Hori, T et. al.

The PI/PTB domain: A new protein interaction domain involved in growth factor receptor signaling
score: 3.3390431, The Journal of Laboratory and Clinical Medicine, 1996, Margolis, Ben

Exosome: from internal vesicle of the multivesicular body to intercellular signaling device.
score: 3.3386899, Journal of cell science, 2000, Denzer, K et. al.

Ku70, a Component of DNA-Dependent Protein Kinase, Is a Mammalian Receptor for Rickettsia conorii
score: 3.3383453, Cell, 2005, Martinez, Juan J. et. al.

Modulation of cell death by Bcl-XL through caspase interaction.
score: 3.3379369, Proceedings of the National Academy of Sciences of the United States of America, 1998, Clem, R J et. al.

Strategies for targeting protein-protein interactions with synthetic agents.
score: 3.3376103, Angewandte Chemie (International ed. in English), 2005, Yin, Hang; Hamilton, Andrew D

Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK.
score: 3.33599, EMBO reports, 2007, Wu, Xuefeng; Sun, Shao-Cong

Molecular biology of the Ets family of transcription factors
score: 3.3359409, Gene, 2003, Oikawa, Tsuneyuki; Yamada, Toshiyuki

cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.
score: 3.3356216, Pharmacological reviews, 2010, Francis, Sharron H et. al.

The ‘Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
score: 3.3350736, Trends in Biochemical Sciences, 2003, Neel, Benjamin G.; Gu, Haihua; Pao, Lily

Elucidation of signaling properties of vasopressin receptor-related receptor 1 by using the chimeric receptor approach.
score: 3.3343418, Proceedings of the National Academy of Sciences of the United States of America, 2004, Gupte, Jamila; Cutler, Gene; Chen, Jin-Long; Tian, Hui

Differential requirement of Tyr1062 multidocking site by RET isoforms to promote neural cell scattering and epithelial cell branching.
score: 3.3336971, Oncogene, 2004, Degl'Innocenti, Debora et. al.

How do inhibitory phosphatases work?
score: 3.3335426, Molecular Immunology, 2002, Coggeshall, K.M; Nakamura, Koji; Phee, Hyewon

Molecular regulation of mast cell activation
score: 3.3327735, The Journal of Allergy and Clinical Immunology, 2006, Rivera, Juan; Gilfillan, Alasdair M.

Syk-dependent phosphorylation of microtubules in activated B-lymphocytes.
score: 3.3314218, Journal of cell science, 2000, Faruki, S; Geahlen, R L; Asai, D J

The mRNA Surveillance Protein hSMG-1 Functions in Genotoxic Stress Response Pathways in Mammalian Cells
score: 3.3310144, Molecular Cell, 2004, Brumbaugh, Kathryn M. et. al.

Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB.
score: 3.3306897, Nature, 2010, Scheuermann, Johanna C et. al.

A viral deubiquitylating enzyme targets viral RNA-dependent RNA polymerase and affects viral infectivity.
score: 3.3302341, The EMBO journal, 2012, Chenon, Mélanie et. al.

Progression of human bone marrow stromal cells into both osteogenic and adipogenic lineages is differentially regulated by structural conformation of collagen I matrix via distinct signaling pathways
score: 3.3298674, Matrix Biology, 2009, Mauney, Josh; Volloch, Vladimir

Regulation of β1-integrin-mediated cell adhesion by the CbI adaptor protein
score: 3.3296855, Current Biology, 1998, Zell, Traci et. al.

TopBP1 Activates the ATR-ATRIP Complex
score: 3.3273621, Cell, 2006, Kumagai, Akiko; Lee, Joon; Yoo, Hae Yong; Dunphy, William G.

Functions of ephrin/Eph interactions in the development of the nervous system: Emphasis on the hippocampal system
score: 3.3266614, Brain Research Reviews, 2005, Martínez, Albert; Soriano, Eduardo

Signal Transduction by the JNK Group of MAP Kinases
score: 3.3262871, Cell, 2000, Davis, Roger J

Betaglycan presents ligand to the TGFβ signaling receptor
score: 3.3259855, Cell, 1993, López-Casillas, Fernando; Wrana, Jeffrey L.; Massagué, Joan

SOCS1 is an inducible host factor during HIV-1 infection and regulates the intracellular trafficking and stability of HIV-1 Gag.
score: 3.3259368, Proceedings of the National Academy of Sciences of the United States of America, 2008, Ryo, Akihide et. al.

Phosphorylation of the stress-activated protein kinase, MEKK3, at serine 166
score: 3.3248614, Archives of Biochemistry and Biophysics, 2002, Adams, Deanna G; Sachs, Nancy A; Vaillancourt, Richard R

Molecular Biology of the Growth Hormone-Prolactin Gene System
score: 3.3242033, Vitamins and Hormones, 1995, Cooke, Nancy E.; Liebhaber, Stephen A.

Molecular Biology of the Growth Hormone-Prolactin Gene System
score: 3.3242033, Vitamins and Hormones, 1995, Cooke, Nancy E.; Liebhaber, Stephen A.

Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region.
score: 3.3241857, Molecular and cellular biology, 2003, Chan, Perry M et. al.

pVHL Acts as an Adaptor to Promote the Inhibitory Phosphorylation of the NF-κB Agonist Card9 by CK2
score: 3.323924, Molecular Cell, 2007, Yang, Haifeng et. al.

Identification of the domain in the human interleukin-11 receptor that mediates ligand binding 1 1 Edited by J. A. Wells
score: 3.3236105, Journal of Molecular Biology, 2001, Schleinkofer, Karin et. al.

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor.
score: 3.3234138, Oncogene, 2003, Penengo, Lorenza et. al.

Cross-regulation of the Wnt signalling pathway: a role of MAP kinases.
score: 3.3230084, Journal of cell science, 2000, Behrens, J

Inhibition of Inflammatory Responses by Leukocyte Ig‐Like Receptors
score: 3.3215771, Advances in Immunology, 2006, Katz, Howard R.

Inhibition of Inflammatory Responses by Leukocyte Ig‐Like Receptors
score: 3.3215771, Advances in Immunology, 2006, Katz, Howard R.

Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
score: 3.3215529, Cell, 1995, Tewari, Muneesh et. al.

Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
score: 3.3200211, Experimental Cell Research, 2006, Myromslien, Frøydis D. et. al.

CD44: Structure, Function and Association with the Malignant Process
score: 3.3193375, Advances in Cancer Research, 1997, Naor, David; Sionov, Ronit Vogt; Ish-Shalom, Dvorah

Signaling by Fibroblast Growth Factors (Fgf) and Fibroblast Growth Factor Receptor 2 (Fgfr2)–Activating Mutations Blocks Mineralization and Induces Apoptosis in Osteoblasts
score: 3.3188835, The Journal of Cell Biology, 2000, Mansukhani, Alka et. al.

Targeting of MIST to Src-family kinases via SKAP55–SLAP-130 adaptor complex in mast cells 1 1 The rat SKAP55 cDNA nucleotide sequence has been deposited in DDBJ database under accession number AB092812.
score: 3.3186211, FEBS Letters, 2003, Fujii, Yasuyuki et. al.

Diversion of stress granules and P-bodies during viral infection
score: 3.3176357, Virology, 2013, Reineke, Lucas C.; Lloyd, Richard E.

Localization of the Lys, Asp, Glu, Leu tetrapeptide receptor to the Golgi complex and the intermediate compartment in mammalian cells
score: 3.3161569, The Journal of Cell Biology, 1994,

Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)
score: 3.3159807, Current Biology, 1998, Dutil, Erica M.; Toker, Alex; Newton, Alexandra C.

All EGF(ErbB) receptors have preformed homo- and heterodimeric structures in living cells.
score: 3.3157527, Journal of cell science, 2008, Tao, Rong-Hua; Maruyama, Ichi N

Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.
score: 3.315499, Proceedings of the National Academy of Sciences of the United States of America, 1990, Shinjo, K et. al.

Evolutionary conservation of P-selectin glycoprotein ligand-1 primary structure and function
score: 3.314764, BMC Evolutionary Biology, 2007, Baïsse, Bénédicte et. al.

Interleukin 2 signaling involves the phosphorylation of Stat proteins.
score: 3.3137732, Proceedings of the National Academy of Sciences of the United States of America, 1995, Frank, D A et. al.

Two Signals Are Necessary for Cell Proliferation Induced by a Cytokine Receptor gp130: Involvement of STAT3 in Anti-Apoptosis
score: 3.3123953, Immunity, 1996, Fukada, Toshiyuki et. al.

Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D.
score: 3.3118518, Journal of immunology (Baltimore, Md. : 1950), 2008, Takada, Akio et. al.

Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice.
score: 3.3112144, Molecular and cellular biology, 2000, Hoemann, C D; Beaulieu, N; Girard, L; Rebai, N; Jolicoeur, P

The Adaptor Protein Crk Controls Activation and Inhibition of Natural Killer Cells
score: 3.3110111, Immunity, 2012, Liu, Dongfang; Peterson, Mary E.; Long, Eric O.

The Adaptor Protein Crk Controls Activation and Inhibition of Natural Killer Cells
score: 3.3110111, Immunity, 2012, Liu, Dongfang; Peterson, Mary E.; Long, Eric O.

G-Protein-Coupled Receptors in Insect Cells
score: 3.3103437, International Review of Cytology, 1996, Vanden Broeck, Jozef J.M.

G-Protein-Coupled Receptors in Insect Cells
score: 3.3103437, International Review of Cytology, 1996, Vanden Broeck, Jozef J.M.

Rho-specific binding and guanine nucleotide exchange catalysis by KIAA0380, a Dbl family member
score: 3.309556, FEBS Letters, 1999, Rümenapp, Ulrich et. al.

Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.
score: 3.3077378, The EMBO journal, 1999, Soldi, R et. al.

Tyrosine phosphorylation regulates alpha II spectrin cleavage by calpain.
score: 3.3068314, Molecular and cellular biology, 2002, Nicolas, Gaël et. al.

Characterization of the B cell-specific adaptor SLP-65 and other protein tyrosine kinase substrates by two-dimensional gel electrophoresis
score: 3.3063722, Immunology Letters, 1999, Wollscheid, Bernd; Reth, Michael; Wienands, Jürgen

Clathrin Potentiates Vaccinia-Induced Actin Polymerization to Facilitate Viral Spread
score: 3.3045671, Cell Host & Microbe, 2012, Humphries, Ashley C. et. al.

Opioids binding mu and delta receptors exhibit diverse efficacy in the activation of Gi2 and G(x/z) transducer proteins in mouse periaqueductal gray matter.
score: 3.3044934, The Journal of pharmacology and experimental therapeutics, 1997, Garzón, J; García-España, A; Sánchez-Blázquez, P

Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation
score: 3.3021227, The Journal of Cell Biology, 2008, Liu, Yunhao et. al.

Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate
score: 3.3011225, Current Biology, 2001, Ramain, Philippe et. al.

Diacylglycerol kinase ζ regulates microbial recognition and host resistance to Toxoplasma gondii
score: 3.3008676, The Journal of Experimental Medicine, 2007, Liu, Cheng-Hu et. al.

Molecular genetics of the RNA polymerase II general transcriptional machinery.
score: 3.2997726, Microbiology and molecular biology reviews : MMBR, 1998, Hampsey, M

Lumenal targeted GFP, used as a marker of soluble cargo, visualises rapid ERGIC to Golgi traffic by a tubulo-vesicular network.
score: 3.2994583, Journal of cell science, 2000, Blum, R; Stephens, D J; Schulz, I

CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation.
score: 3.2975557, Journal of immunology (Baltimore, Md. : 1950), 2000, Michel, F et. al.

Differential tyrosine phosphorylation of fibroblast growth factor (FGF) receptor-1 and receptor proximal signal transduction in response to FGF-2 and heparin
score: 3.2961447, Experimental Cell Research, 2003, Lundin, Lars et. al.

Survivin: A Protein with Dual Roles in Mitosis and Apoptosis
score: 3.2957398, International Review of Cytology, 2005, Wheatley, Sally P.; McNeish, Iain A.

Nuclear Import of Human Immunodeficiency Virus Type-1 Preintegration Complexes
score: 3.2938995, Advances in Virus Research, 1999, Fouchier, Ron A.M.; Malim, Michael H.

Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene.
score: 3.2937308, Proceedings of the National Academy of Sciences of the United States of America, 1991, Vetter, M L et. al.

Enzymatic Activity Associated with Class II HDACs Is Dependent on a Multiprotein Complex Containing HDAC3 and SMRT/N-CoR
score: 3.2934875, Molecular Cell, 2002, Fischle, Wolfgang et. al.

Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells
score: 3.293434, The Journal of Cell Biology, 2006, Darzacq, Xavier et. al.

A pleckstrin homology-related domain in SHIP1 mediates membrane localization during Fcγ receptor-induced phagocytosis.
score: 3.2922088, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Ming-Lum, Andrew et. al.

p21-activated kinase 2 in neutrophils can be regulated by phosphorylation at multiple sites and by a variety of protein phosphatases.
score: 3.2906667, Journal of immunology (Baltimore, Md. : 1950), 2003, Zhan, Qian et. al.

Sprouty-2 controls c-Met expression and metastatic potential of colon cancer cells: sprouty/c-Met upregulation in human colonic adenocarcinomas.
score: 3.2902576, Oncogene, 2010, Holgren, C et. al.

Identification of Shc docking site on Ret tyrosine kinase.
score: 3.2901272, Oncogene, 1997, Arighi, E et. al.

Unexpected Effects of FERM Domain Mutations on Catalytic Activity of Jak3
score: 3.2899668, Molecular Cell, 2001, Zhou, Yong-Jie et. al.

Cathepsin S Controls the Trafficking and Maturation of Mhc Class II Molecules in Dendritic Cells
score: 3.289875, The Journal of Cell Biology, 1999, Driessen, Christoph et. al.

Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro.
score: 3.2881815, The EMBO journal, 1997, Stokoe, D; McCormick, F

Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly
score: 3.2878729, The Journal of Cell Biology, 2006, Chen, Xinyu; Macara, Ian G.

Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density.
score: 3.2874624, Proceedings of the National Academy of Sciences of the United States of America, 1994, Ostman, A; Yang, Q; Tonks, N K

Molecular determinants that mediate selective activation of p38 MAP kinase isoforms.
score: 3.2864098, The EMBO journal, 2000, Enslen, H; Brancho, D M; Davis, R J

Phosphorylation by p34 cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
score: 3.2862603, Cell, 1995, Slangy, Anne et. al.

Fas ligand/Fas system in the brain: regulator of immune and apoptotic responses
score: 3.2856263, Brain Research Reviews, 2004, Choi, Chulhee; Benveniste, Etty N.

CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML)
score: 3.2852022, Cancer Cell, 2002, Kelly, Louise M et. al.

AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner.
score: 3.2842352, Molecular cancer research : MCR, 2005, Felekkis, Kyriacos N et. al.

Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors.
score: 3.2834918, Journal of cell science, 2005, Haugsten, Ellen Margrethe et. al.

Neuronal and glial cell biology
score: 3.2828094, Current Opinion in Neurobiology, 1996,

The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release
score: 3.2826963, Microbes and Infection, 2003, Bour, Stephan; Strebel, Klaus

Fibroblast growth factors and their receptors: An information network controlling tissue growth, morphogenesis and repair
score: 3.2806995, Progress in Growth Factor Research, 1994, Fernig, David G; Gallagher, John T

The Hypoxia-Inducible Factor and Tumor Progression Along the Angiogenic Pathway
score: 3.2801551, International Review of Cytology, 2004, Brahimi-Horn, M.Christiane; Pouysségur, Jacques

The Hypoxia-Inducible Factor and Tumor Progression Along the Angiogenic Pathway
score: 3.2801551, International Review of Cytology, 2004, Brahimi-Horn, M.Christiane; Pouysségur, Jacques

Toll-like receptor 4, but not toll-like receptor 2, is a signaling receptor for Escherichia and Salmonella lipopolysaccharides.
score: 3.2786997, Journal of immunology (Baltimore, Md. : 1950), 2000, Tapping, R I et. al.

Amino acid motifs required for isolated beta cytoplasmic domains to regulate 'in trans' beta1 integrin conformation and function in cell attachment.
score: 3.2778195, Journal of cell science, 1999, Mastrangelo, A M; Homan, S M; Humphries, M J; LaFlamme, S E

The Cellular Context of T Cell Signaling
score: 3.2778132, Immunity, 2009, Dustin, Michael L.

PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models
score: 3.2771493, Trends in Immunology, 2001, Astoul, Emmanuelle et. al.

her1, a zebrafish pair-rule like gene, acts downstream of notch signalling to control somite development.
score: 3.2765476, Development (Cambridge, England), 1999, Takke, C; Campos-Ortega, J A

Specificity of peripheral nerve regeneration: Interactions at the axon level
score: 3.2763884, Progress in Neurobiology, 2012, Allodi, Ilary; Udina, Esther; Navarro, Xavier

Specificity of peripheral nerve regeneration: Interactions at the axon level
score: 3.2763884, Progress in Neurobiology, 2012, Allodi, Ilary; Udina, Esther; Navarro, Xavier

Specificity of peripheral nerve regeneration: Interactions at the axon level
score: 3.2763884, Progress in Neurobiology, 2012, Allodi, Ilary; Udina, Esther; Navarro, Xavier

Regulation of skeletal myogenesis by Notch
score: 3.2755509, Experimental Cell Research, 2010, Buas, Matthew F.; Kadesch, Tom

Regulation of D1 dopamine receptor trafficking and signaling by caveolin-1.
score: 3.2752653, Molecular pharmacology, 2007, Kong, Michael M C et. al.

Expression of VACM-1/cul5 mutant in endothelial cells induces MAPK phosphorylation and maspin degradation and converts cells to the angiogenic phenotype
score: 3.2748256, Microvascular Research, 2008, Buchwalter, A. et. al.

Lipids and atherosclerosis
score: 3.2743258, Molecular Aspects of Medicine, 1995, Halpern, Manuel Júdice

CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A.
score: 3.2742969, Journal of immunology (Baltimore, Md. : 1950), 2001, Shlapatska, L M et. al.

A large complex mediated by Moc1, Moc2 and Cpc2 regulates sexual differentiation in fission yeast.
score: 3.27387, The FEBS journal, 2009, Paul, Swapan Kumar; Oowatari, Yasuo; Kawamukai, Makoto

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity
score: 3.272509, Cell, 1991, Boyle, William J. et. al.

Toll-Like Receptors and RNA Helicases: Two Parallel Ways to Trigger Antiviral Responses
score: 3.2717225, Molecular Cell, 2006, Meylan, Etienne; Tschopp, Jürg

Achondroplasia
score: 3.2711505, The Lancet, 2007, Horton, William A; Hall, Judith G; Hecht, Jacqueline T

Drosophila Nemo antagonizes BMP signaling by phosphorylation of Mad and inhibition of its nuclear accumulation.
score: 3.2708351, Development (Cambridge, England), 2007, Zeng, Yi Arial et. al.

Isolation of an additional member of the fibroblast growth factor receptor family, FGFR-3.
score: 3.2703393, Proceedings of the National Academy of Sciences of the United States of America, 1991, Keegan, K; Johnson, D E; Williams, L T; Hayman, M J

Transport-Dependent Proteolysis of SREBP
score: 3.270116, Cell, 1999, DeBose-Boyd, Russell A et. al.

A new linear V1A vasopressin antagonist and its use in characterizing receptor/G protein interactions.
score: 3.2693101, Molecular pharmacology, 1997, Strakova, Z; Kumar, A; Watson, A J; Soloff, M S

Stat5B shuttles between cytoplasm and nucleus in a cytokine-dependent and -independent manner.
score: 3.2683151, Journal of immunology (Baltimore, Md. : 1950), 2002, Zeng, Rong et. al.

Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix
score: 3.2682686, Retrovirology, 2012, Kuo, Lillian S et. al.

Glucose transporter 4: cycling, compartments and controversies.
score: 3.2680789, EMBO reports, 2005, Dugani, Chandrasagar B; Klip, Amira

Intracellular lectins associated with N-linked glycoprotein traffic
score: 3.267851, BBA - General Subjects, 1999, Yamashita, Katsuko; Hara-Kuge, Sayuri; Ohkura, Takashi

Bibliography of the current world literature
score: 3.2677891, Current Opinion in Cell Biology, 1991,

Inhibition of a naturally occurring EGFR oncoprotein by the p185neu ectodomain: implications for subdomain contributions to receptor assembly.
score: 3.2669916, Oncogene, 1998, O'Rourke, D M et. al.

Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport.
score: 3.2665166, The EMBO journal, 2003, Hoogenraad, Casper C et. al.

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
score: 3.265861, Cell, 1994, Dérijard, Benoit et. al.

Bovine natural killer cells
score: 3.2656815, Veterinary Immunology and Immunopathology, 2009, Boysen, Preben; Storset, Anne K.

C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and associate with each other and with CD4 or CD8 in T cells.
score: 3.2653691, Journal of immunology (Baltimore, Md. : 1950), 1993, Imai, T; Yoshie, O

ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling.
score: 3.2651387, Molecular and cellular biology, 2006, Grewal, Prabhjit K et. al.

Leukocyte cell surface proteinases: Regulation of expression, functions, and mechanisms of surface localization
score: 3.2645699, International Journal of Biochemistry and Cell Biology, 2008, Owen, Caroline A.

EHD1 regulates beta1 integrin endosomal transport: effects on focal adhesions, cell spreading and migration.
score: 3.2645143, Journal of cell science, 2007, Jović, Marko et. al.

Cranial Suture Biology
score: 3.2645098, Current Topics in Developmental Biology, 2005, Lenton, Kelly A et. al.

Cranial Suture Biology
score: 3.2645098, Current Topics in Developmental Biology, 2005, Lenton, Kelly A et. al.

To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways
score: 3.2645056, Progress in Neurobiology, 2003, Liou, Anthony K.F et. al.

A Widespread and Early Requirement for a Novel Notch Function during Drosophila Embryogenesis
score: 3.2641085, Developmental Biology, 1999, Rusconi, Jamie C.; Corbin, Victoria

Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins
score: 3.263943, EMBO Molecular Medicine, 2011, Kawai, Taro; Akira, Shizuo

CIKS, a connection to Ikappa B kinase and stress-activated protein kinase.
score: 3.2636115, Proceedings of the National Academy of Sciences of the United States of America, 2000, Leonardi, A et. al.

Visualization of Syk-antigen receptor interactions using green fluorescent protein: differential roles for Syk and Lyn in the regulation of receptor capping and internalization.
score: 3.2625653, Journal of immunology (Baltimore, Md. : 1950), 2001, Ma, H et. al.

High‐Level Expression and Purification of Recombinant SCF Ubiquitin Ligases
score: 3.2620494, Methods in Enzymology, 2005, Li, Ti et. al.

High‐Level Expression and Purification of Recombinant SCF Ubiquitin Ligases
score: 3.2620494, Methods in Enzymology, 2005, Li, Ti et. al.

Mitochondrial antiviral signaling protein plays a major role in induction of the fish innate immune response against RNA and DNA viruses.
score: 3.2618367, Journal of virology, 2009, Biacchesi, Stéphane et. al.

Mast cells express novel functional IL-15 receptor alpha isoforms.
score: 3.2618008, Journal of immunology (Baltimore, Md. : 1950), 2003, Bulanova, Elena et. al.

Src Homology 2 Protein Tyrosine Phosphatase (SHPTP2)/Src Homology 2 Phosphatase 2 (SHP2) Tyrosine Phosphatase Is a Positive Regulator of the Interleukin 5 Receptor Signal Transduction Pathways Leading to the Prolongation of Eosinophil Survival
score: 3.2614405, The Journal of Experimental Medicine, 1997, Pazdrak, Konrad; Adachi, Tetsuya; Alam, Rafeul

beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.
score: 3.2603535, Proceedings of the National Academy of Sciences of the United States of America, 1998, Premont, R T et. al.

Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents.
score: 3.2602341, Oncogene, 2003, Nickoloff, Brian J; Osborne, Barbara A; Miele, Lucio

Distinct intracellular motifs of Delta mediate its ubiquitylation and activation by Mindbomb1 and Neuralized
score: 3.2599516, The Journal of Cell Biology, 2011, Daskalaki, Aikaterini et. al.

The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif
score: 3.258788, Immunity, 1995, Lindstedt, Ragnar et. al.

The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors.
score: 3.2584108, The EMBO journal, 2002, Yamakawa, Norio; Tsuchida, Kunihiro; Sugino, Hiromu

JAGGED2: a putative Notch ligand expressed in the apical ectodermal ridge and in sites of epithelial–mesenchymal interactions
score: 3.2581861, Mechanisms of Development, 1997, Valsecchi, Valentina et. al.

Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1.
score: 3.2575234, The EMBO journal, 2006, Hernandez-Hernandez, Angel et. al.

Beyond desensitization: physiological relevance of arrestin-dependent signaling.
score: 3.2560614, Pharmacological reviews, 2010, Luttrell, Louis M; Gesty-Palmer, Diane

Protein engineering
score: 3.255718, Current Opinion in Biotechnology, 1991,

Mps1 Phosphorylates Borealin to Control Aurora B Activity and Chromosome Alignment
score: 3.255625, Cell, 2008, Jelluma, Nannette et. al.

Apoptosis, Part I: Biochemical assessment
score: 3.2556221, Advances in Clinical Chemistry, 2001, Lam, Christopher Wai Kei; Wong, Chun Kwok

Apoptosis, Part I: Biochemical assessment
score: 3.2556221, Advances in Clinical Chemistry, 2001, Lam, Christopher Wai Kei; Wong, Chun Kwok

Role of HER-2/neu signaling in sensitivity to tumor necrosis factor-related apoptosis-inducing ligand: enhancement of TRAIL-mediated apoptosis by amiloride.
score: 3.2533867, Journal of cellular biochemistry, 2005, Kim, Ki M; Lee, Yong J

Regulation of translation via mRNA structure in prokaryotes and eukaryotes
score: 3.2524887, Gene, 2005, Kozak, Marilyn

ERK/p90 RSK /14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicúa
score: 3.2500874, Biochemical Journal, 2010, Dissanayake, Kumara et. al.

Lymphotoxin β, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface
score: 3.250054, Cell, 1993, Browning, Jeffrey L. et. al.

Ras pathway signaling on endomembranes
score: 3.2493306, Current Opinion in Cell Biology, 2003, Bivona, Trever G; Philips, Mark R

Structural and functional bases for allosteric control of MMP activities: Can it pave the path for selective inhibition?
score: 3.2488017, BBA - Molecular Cell Research, 2010, Sela-Passwell, Netta et. al.

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.
score: 3.2481151, Proceedings of the National Academy of Sciences of the United States of America, 1994, Narazaki, M et. al.

Recruitment of Nck by CD3ϵ Reveals a Ligand-Induced Conformational Change Essential for T Cell Receptor Signaling and Synapse Formation
score: 3.2481125, Cell, 2002, Gil, Diana et. al.

A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription.
score: 3.2478993, Proceedings of the National Academy of Sciences of the United States of America, 1995, Mäkelä, T P et. al.

The Four Distal Tyrosines Are Required for LAT-dependent Signaling in FcɛRI-mediated Mast Cell Activation
score: 3.2474207, The Journal of Experimental Medicine, 2003, Saitoh, Shin-ichiroh et. al.

Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.
score: 3.2473281, Molecular and cellular biology, 2002, Yan, Yu-Ting et. al.

Wnt-ligand-dependent interaction of TAK1 (TGF-β-activated kinase-1) with the receptor tyrosine kinase Ror2 modulates canonical Wnt-signalling
score: 3.2468321, Cellular Signalling, 2008, Winkel, Andreas et. al.

Junctional protein MAGI-3 interacts with receptor tyrosine phosphatase beta (RPTP beta) and tyrosine-phosphorylated proteins.
score: 3.2450232, Journal of cell science, 2003, Adamsky, Konstantin et. al.

Cdc20: A WD40 Activator for a Cell Cycle Degradation Machine
score: 3.244906, Molecular Cell, 2007, Yu, Hongtao

Mutational Analysis of the L1 Neuronal Cell Adhesion Molecule Identifies Membrane-Proximal Amino Acids of the Cytoplasmic Domain That Are Required for Cytoskeletal Anchorage
score: 3.2445936, Molecular and Cellular Neuroscience, 1997, Dahlin-Huppe, Kimberlee et. al.

Dynamic interplay of transcriptional machinery and chromatin regulates "late" expression of the chemokine RANTES in T lymphocytes.
score: 3.2442125, Molecular and cellular biology, 2007, Ahn, Yong-Tae et. al.

Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants.
score: 3.2429588, Journal of leukocyte biology, 1998, O'Neill, L A; Greene, C

Structural insights into the Slit-Robo complex.
score: 3.242934, Proceedings of the National Academy of Sciences of the United States of America, 2007, Morlot, Cecile et. al.

Hbo1 Links p53-dependent stress signaling to DNA replication licensing.
score: 3.2426235, Molecular and cellular biology, 2008, Iizuka, Masayoshi et. al.

G proteins
score: 3.2426109, Trends in Biochemical Sciences, 1992, Hepler, John R.; Gilman, Alfred G.

Molecular mechanisms of muscarinic acetylcholine receptor–stimulated increase in cytosolic free Ca 2+ concentration and ERK1/2 activation in the MIN6 pancreatic β-cell line
score: 3.2415216, Acta Diabetologica, 2011, Selway, Joanne L. et. al.

Stability of an autoinhibitory interface in the structure of the tyrosine kinase ZAP-70 impacts T cell receptor response.
score: 3.2408915, Proceedings of the National Academy of Sciences of the United States of America, 2009, Deindl, Sebastian et. al.

Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo.
score: 3.2396364, Molecular and cellular biology, 1997, Ravichandran, K S et. al.

Lipopolysaccharide-induced activation of beta2-integrin function in macrophages requires Irak kinase activity, p38 mitogen- activated protein kinase, and the Rap1 GTPase.
score: 3.2395825, Molecular and cellular biology, 2001, Schmidt, A; Caron, E; Hall, A

Multiple cell surface receptors for the short arms of laminin: alpha 1 beta 1 integrin and RGD-dependent proteins mediate cell attachment only to domains III in murine tumor laminin
score: 3.2368144, The Journal of Cell Biology, 1991,

Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.
score: 3.2365372, Proceedings of the National Academy of Sciences of the United States of America, 1998, Nohturfft, A; Brown, M S; Goldstein, J L

PY motifs of Epstein-Barr virus LMP2A regulate protein stability and phosphorylation of LMP2A-associated proteins.
score: 3.235696, Journal of virology, 2001, Ikeda, M; Ikeda, A; Longnecker, R

Analysis of CD28 cytoplasmic tail tyrosine residues as regulators and substrates for the protein tyrosine kinases, EMT and LCK.
score: 3.235583, Journal of immunology (Baltimore, Md. : 1950), 1997, King, P D et. al.

The HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitor.
score: 3.2347839, Proceedings of the National Academy of Sciences of the United States of America, 1999, Doherty, J K; Bond, C; Jardim, A; Adelman, J P; Clinton, G M

The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration.
score: 3.2347713, Journal of cell science, 2009, Bristow, Jeanne M et. al.

P210 Bcr-Abl interacts with the interleukin 3 receptor beta(c) subunit and constitutively induces its tyrosine phosphorylation.
score: 3.2344225, Cancer research, 1996, Wilson-Rawls, J et. al.

c-Cbl binds to tyrosine-phosphorylated neurotrophin receptor p75 and induces its ubiquitination
score: 3.2342066, Cellular Signalling, 2004, Ohrt, Thomas et. al.

Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation.
score: 3.234122, Molecular and cellular biology, 1996, Bazenet, C E; Gelderloos, J A; Kazlauskas, A

Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis.
score: 3.2332975, Development (Cambridge, England), 2007, Patel, Vaishali N et. al.

The Molecular Basis for the Endocytosis of Small R-SNAREs by the Clathrin Adaptor CALM
score: 3.232528, Cell, 2011, Miller, Sharon E. et. al.

Phosphorylation of Numb regulates its interaction with the clathrin-associated adaptor AP-2
score: 3.2321177, FEBS Letters, 2006, Tokumitsu, Hiroshi et. al.

Ubiquitin-dependent internalization and down-regulation of plasma membrane proteins.
score: 3.2318597, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1997, Hicke, L

Assembly and Maturation of the U3 snoRNP in the Nucleoplasm in a Large Dynamic Multiprotein Complex
score: 3.2315621, Molecular Cell, 2004, Watkins, Nicholas J. et. al.

Nuclear localization of the Escherichia coli cytolethal distending toxin CdtB subunit.
score: 3.2310605, Cellular microbiology, 2004, McSweeney, Leslie A; Dreyfus, Lawrence A

Effect of Long-Term Exercise on Gene Expression of Insulin Signaling Pathway Intermediates in Skeletal Muscle
score: 3.2308628, Biochemical and Biophysical Research Communications, 1999, Kim, Young-Bum et. al.

Comparative TFIIS-mediated transcript cleavage by mammalian RNA polymerase II arrested at a lesion in different transcription systems
score: 3.230599, DNA Repair, 2005, Kalogeraki, Virginia S. et. al.

Genetic approaches to the study of Toll-like receptor function
score: 3.2305139, Microbes and Infection, 2002, Takeuchi, Osamu; Akira, Shizuo

Downregulation of class I major histocompatibility complex surface expression by varicella-zoster virus involves open reading frame 66 protein kinase-dependent and -independent mechanisms.
score: 3.2305083, Journal of virology, 2007, Eisfeld, Amie J et. al.

HZwint-1, a novel human kinetochore component that interacts with HZW10.
score: 3.2304774, Journal of cell science, 2000, Starr, D A et. al.

High-throughput analysis of peptide-binding modules.
score: 3.2303138, Proteomics, 2012, Liu, Bernard A; Engelmann, Brett W; Nash, Piers D

Biochemical dissection of AP-1 recruitment onto Golgi membranes
score: 3.2303, The Journal of Cell Biology, 1993,

MAPKAP kinases - MKs - two's company, three's a crowd.
score: 3.230192, Nature reviews. Molecular cell biology, 2006, Gaestel, Matthias

Molecular mechanisms of IgE regulation
score: 3.2301846, The Journal of Allergy and Clinical Immunology, 2000, Bacharier, Leonard B.; Geha, Raif S.

JNK signaling pathway is required for bFGF-mediated surface cadherin downregulation on HUVEC
score: 3.2300092, Experimental Cell Research, 2008, Wu, Jen-Chine et. al.

A Critical Role for Syk in Signal Transduction and Phagocytosis Mediated by Fcγ Receptors on Macrophages
score: 3.2298857, The Journal of Experimental Medicine, 1997, Crowley, Mary T. et. al.

Intracellular messengers and the control of protein synthesis
score: 3.2294647, Pharmacology and Therapeutics, 1991, Morley, Simon J.; Thomas, George

Rat and Mouse CD94 Associate Directly with the Activating Transmembrane Adaptor Proteins DAP12 and DAP10 and Activate NK Cell Cytotoxicity.
score: 3.2293455, Journal of immunology (Baltimore, Md. : 1950), 2011, Saether, Per C et. al.

Myosin-X is a molecular motor that functions in filopodia formation.
score: 3.2290488, Proceedings of the National Academy of Sciences of the United States of America, 2006, Bohil, Aparna B; Robertson, Brian W; Cheney, Richard E

Roles of the Wnt effector POP-1/TCF in the C. elegans endomesoderm specification gene network
score: 3.2288424, Developmental Biology, 2010, Owraghi, Melissa et. al.

Characterization of mammalian Par 6 as a dual-location protein.
score: 3.2287702, Molecular and cellular biology, 2007, Cline, Erin G; Nelson, W James

Notch signaling induces cell cycle arrest in small cell lung cancer cells.
score: 3.2285597, Cancer research, 2001, Sriuranpong, V et. al.

Delineation of RAID1, the RACK1 interaction domain located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5
score: 3.2284628, BMC Biochemistry, 2002, Bolger, Graeme B et. al.

Dendritic LSm1/CBP80-mRNPs mark the early steps of transport commitment and translational control
score: 3.2277403, The Journal of Cell Biology, 2009, di Penta, Alessandra et. al.

A role for phosphatidylinositol 3-kinase in the regulation of beta 1 integrin activity by the CD2 antigen
score: 3.2274401, The Journal of Cell Biology, 1995,

RNA polymerase II holoenzyme modifications accompany transcription reprogramming in herpes simplex virus type 1-infected cells.
score: 3.227149, Journal of virology, 2001, Jenkins, H L; Spencer, C A

Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling.
score: 3.2266153, Molecular and cellular biology, 1997, Rui, L; Mathews, L S; Hotta, K; Gustafson, T A; Carter-Su, C

Rad52 recruitment is DNA replication independent and regulated by Cdc28 and the Mec1 kinase.
score: 3.2263465, The EMBO journal, 2009, Barlow, Jacqueline H; Rothstein, Rodney

Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit
score: 3.2255933, Cancer Cell, 2002, Chan, Tung O. et. al.

Innate recognition of lipopolysaccharide by CD14 and toll-like receptor 4-MD-2: unique roles for MD-2
score: 3.2255497, International Immunopharmacology, 2003, Miyake, Kensuke

Signalling complexes and clusters: functional advantages and methodological hurdles.
score: 3.2254666, Journal of cell science, 2010, Cebecauer, Marek et. al.

The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity.
score: 3.2253405, The EMBO journal, 2007, Poyurovsky, Masha V et. al.

Feedback Inhibition of the Unfolded Protein Response by GADD34 -Mediated Dephosphorylation of eIF2α
score: 3.2247702, The Journal of Cell Biology, 2001, Novoa, Isabel et. al.

Peptides derived from specific interaction sites of the fibroblast growth factor 2-FGF receptor complexes induce receptor activation and signaling.
score: 3.2245159, Journal of neurochemistry, 2010, Manfè, Valentina et. al.

Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-β Pathways
score: 3.224279, Structure, 2012, Aragón, Eric et. al.

Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-β Pathways
score: 3.224279, Structure, 2012, Aragón, Eric et. al.

Regulation and Destabilization of HIF-1α by ARD1-Mediated Acetylation
score: 3.2215138, Cell, 2002, Jeong, Joo-Won et. al.

A regulator of G Protein signaling, RGS3, inhibits gonadotropin-releasing hormone (GnRH)-stimulated luteinizing hormone (LH) secretion
score: 3.2208005, BMC Cell Biology, 2001, Neill, Jimmy D et. al.

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4.
score: 3.2204836, Nature, 2010, Metzger, Eric et. al.

Characterization of PDZ-binding kinase, a mitotic kinase.
score: 3.2204581, Proceedings of the National Academy of Sciences of the United States of America, 2000, Gaudet, S; Branton, D; Lue, R A

Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation.
score: 3.2203136, Oncogene, 2009, Liao, Y et. al.

Cytotoxic Lymphocyte Recognition of HLA-E
score: 3.2201875, Immunity, 1998, Leibson, Paul J

The CD43 coreceptor molecule recruits the zeta-chain as part of its signaling pathway.
score: 3.2197259, Journal of immunology (Baltimore, Md. : 1950), 2003, Cruz-Muñoz, Mario Ernesto et. al.

A review on pro- and anti-angiogenic factors as targets of clinical intervention
score: 3.219444, Pharmacological Research, 2006, Bouïs, Diane et. al.

ICAP-1, a Novel β 1 Integrin Cytoplasmic Domain–associated Protein, Binds to a Conserved and Functionally Important NPXY Sequence Motif of β 1 Integrin
score: 3.2192836, The Journal of Cell Biology, 1997, Chang, David D.; Wong, Carol; Smith, Healy; Liu, Jenny

Messenger RNA decay during aging and development
score: 3.218635, Ageing Research Reviews, 2002, Brewer, Gary

Modified SH2 domain to phototrap and identify phosphotyrosine proteins from subcellular sites within cells.
score: 3.2184317, Proceedings of the National Academy of Sciences of the United States of America, 2012, Uezu, Akiyoshi et. al.

Cell Signaling by Receptor Tyrosine Kinases
score: 3.217691, Cell, 2010, Lemmon, Mark A.; Schlessinger, Joseph

Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity
score: 3.2168883, Cell, 1993, Ayer, Donald E.; Kretzner, Leo; Eisenman, Robert N.

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis.
score: 3.216501, Nature reviews. Molecular cell biology, 2010, Moynahan, Mary Ellen; Jasin, Maria

Mal connects TLR2 to PI3Kinase activation and phagocyte polarization.
score: 3.2158015, The EMBO journal, 2009, Santos-Sierra, Sandra et. al.

Mutated fukutin-related protein (FKRP) localises as wild type in differentiated muscle cells
score: 3.21528, Experimental Cell Research, 2005, Dolatshad, N.F. et. al.

Turnover in the Alps: an mRNA perspective. Workshops on mechanisms and regulation of mRNA turnover.
score: 3.2132501, EMBO reports, 2006, Newbury, Sarah F; Mühlemann, Oliver; Stoecklin, Georg

Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), a novel Hsp90-client tyrosine kinase: down-regulation of NPM-ALK expression and tyrosine phosphorylation in ALK(+) CD30(+) lymphoma cells by the Hsp90 antagonist 17-allylamino,17-demethoxygeldanamycin.
score: 3.2131723, Cancer research, 2002, Bonvini, Paolo et. al.

Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization.
score: 3.2129318, Molecular and cellular biology, 2008, Blasutig, Ivan M et. al.

FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts.
score: 3.2123765, The EMBO journal, 2003, Bois, Philippe R J; Grosveld, Gerard C

Viral strategies for evading antiviral cellular immune responses of the host.
score: 3.2122799, Journal of leukocyte biology, 2006, Iannello, Alexandre et. al.

Regulation of cell-cell interactions by phosphatidic acid phosphatase 2b/VCIP.
score: 3.211856, The EMBO journal, 2003, Humtsoe, Joseph O et. al.

The DEAD-box RNA helicase DDX3 interacts with DDX5, co-localizes with it in the cytoplasm during the G(2) /M phase of the cycle, and affects its shuttling during mRNP export.
score: 3.2117331, Journal of cellular biochemistry, 2012, Choi, Yeo-Jin; Lee, Seong-Gene

Association and regulation of heat shock transcription factor 4b with both extracellular signal-regulated kinase mitogen-activated protein kinase and dual-specificity tyrosine phosphatase DUSP26.
score: 3.211691, Molecular and cellular biology, 2006, Hu, Yanzhong; Mivechi, Nahid F

Cytomegalovirus MHC class I homologues and natural killer cells: an overview
score: 3.2115474, Microbes and Infection, 2000, Farrell, Helen et. al.

Impaired NFAT transcriptional activity in antigen-stimulated CD8 T cells linked to defective phosphorylation of NFAT transactivation domain.
score: 3.2115164, Journal of immunology (Baltimore, Md. : 1950), 2009, Leung-Theung-Long, Stéphane et. al.

Mixed-lineage kinase control of JNK and p38 MAPK pathways.
score: 3.211169, Nature reviews. Molecular cell biology, 2002, Gallo, Kathleen A; Johnson, Gary L

Regiospecific Phosphorylation Control of the SR Protein ASF/SF2 by SRPK1
score: 3.211151, Journal of Molecular Biology, 2009, Ma, Chen-Ting et. al.

SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription.
score: 3.2105724, Molecular and cellular biology, 2002, Wu, Liangtang; Fu, Jun; Shen, Shi-Hsiang

Sterol regulatory element-binding protein family as global regulators of lipid synthetic genes in energy metabolism
score: 3.2104104, Vitamins and Hormones, 2002, Shimano, Hitoshi

Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53.
score: 3.2086623, Journal of virology, 2006, Borger, Darrell R; DeCaprio, James A

Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.
score: 3.2086397, Proceedings of the National Academy of Sciences of the United States of America, 2003, Calderwood, David A et. al.

The interleukin-4 receptor: signal transduction by a hematopoietin receptor.
score: 3.2072199, Journal of leukocyte biology, 1994, Keegan, A D; Pierce, J H

Enterovirus 71 induces degradation of TRIM38, a potential E3 ubiquitin ligase
score: 3.2069172, Virology Journal, 2011, Liu, Xinlei et. al.

Insulin, insulin-like growth factor-I (IGF-I) and glucagon: the evolution of their receptors 1 This review is dedicated to Professor José Planas, who died in December 1995. Professor J. Planas was the pioneer on the studies of fish insulin and glucagon in Spain and founded this research group at the University of Barcelona. Professor J. Planas always stimulated the international cooperation of which this review is an example. He will always remain with us. 1
score: 3.2068401, Comparative Biochemistry and Physiology, Part B, 1999, Navarro, I et. al.

Toll receptors: a central element in innate immune responses.
score: 3.206294, Infection and immunity, 2002, Vasselon, Thierry; Detmers, Patricia A

Drosophila Ndfip is a novel regulator of Notch signaling.
score: 3.2061655, Cell death and differentiation, 2011, Dalton, H E et. al.

Signaling and ligand binding by recombinant neuromedin U receptors: evidence for dual coupling to Galphaq/11 and Galphai and an irreversible ligand-receptor interaction.
score: 3.2059244, Molecular pharmacology, 2004, Brighton, Paul J et. al.

Condensin I Stabilizes Chromosomes Mechanically through a Dynamic Interaction in Live Cells
score: 3.2058186, Current Biology, 2006, Gerlich, Daniel et. al.

Genetic analysis of an overlapping functional requirement for L1- and NCAM-type proteins during sensory axon guidance in Drosophila
score: 3.2053332, Molecular and Cellular Neuroscience, 2005, Kristiansen, Lars V. et. al.

Role of cytoplasmic C-terminal amino acids of membrane proteins in ER export.
score: 3.2050687, Journal of cell science, 2002, Nufer, Oliver et. al.

Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression.
score: 3.2047008, Journal of immunology (Baltimore, Md. : 1950), 2000, Nomura, F et. al.

The Cohesion Protein MEI-S332 Localizes to Condensed Meiotic and Mitotic Centromeres until Sister Chromatids Separate
score: 3.2040668, The Journal of Cell Biology, 1998, Moore, Daniel P. et. al.

Reconstitution of COPII vesicle fusion to generate a pre-Golgi intermediate compartment
score: 3.2040251, The Journal of Cell Biology, 2004, Xu, Dalu; Hay, Jesse C.

Making sense of the diverse ligand recognition by NKG2D.
score: 3.2031107, Journal of immunology (Baltimore, Md. : 1950), 2002, Radaev, Sergei et. al.

Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation.
score: 3.2022826, Journal of immunology (Baltimore, Md. : 1950), 2000, Anhuf, D et. al.

Two differently regulated nuclear factor kappaB activation pathways triggered by the cytoplasmic tail of CD40.
score: 3.2009839, Proceedings of the National Academy of Sciences of the United States of America, 1999, Tsukamoto, N; Kobayashi, N; Azuma, S; Yamamoto, T; Inoue, J

Phosphorylation of the cyclin-dependent kinase inhibitor p21Cip1 on serine 130 is essential for viral cyclin-mediated bypass of a p21Cip1-imposed G1 arrest.
score: 3.2004529, Molecular and cellular biology, 2006, Järviluoma, Annika et. al.

The diversity and possible functions of the inositol polyphosphate 5-phosphatases
score: 3.2001792, BBA - Molecular and Cell Biology of Lipids, 1998, Erneux, Christophe et. al.

Induction of allergic inflammation by interleukin-18 in experimental animal models.
score: 3.1996565, Immunological reviews, 2004, Tsutsui, Hiroko et. al.

Human microvascular endothelial cells express receptors for platelet-derived growth factor.
score: 3.199325, Proceedings of the National Academy of Sciences of the United States of America, 1991, Beitz, J G; Kim, I S; Calabresi, P; Frackelton, A R

Glucose Signaling-Mediated Coordination of Cell Growth and Cell Cycle in Saccharomyces Cerevisiae
score: 3.1980424, Sensors (Basel, Switzerland), 2010, Busti, Stefano et. al.

Mastermind-like transcriptional co-activators: emerging roles in regulating cross talk among multiple signaling pathways.
score: 3.1972899, Oncogene, 2008, McElhinny, A S; Li, J-L; Wu, L

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes
score: 3.1972461, Molecular Cell, 2012, Gao, Zhonghua et. al.

Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs
score: 3.1961199, Structure, 2007, Eswaran, Jeyanthy et. al.

Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs
score: 3.1961199, Structure (London, England : 1993), 2007, Eswaran, Jeyanthy et. al.

CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes.
score: 3.1949542, Journal of immunology (Baltimore, Md. : 1950), 2003, Parry, Richard V et. al.

Ran-binding protein 5 (RanBP5) is related to the nuclear transport factor importin-beta but interacts differently with RanBP1.
score: 3.1939644, Molecular and cellular biology, 1997, Deane, R et. al.

The Formin-Homology Protein SmDia Interacts with the Src Kinase SmTK and the GTPase SmRho1 in the Gonads of Schistosoma mansoni
score: 3.1937552, PLoS ONE, 2009, Quack, Thomas et. al.

Syndecan-1 regulates α v β 3 and α v β 5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor
score: 3.193202, The Journal of Experimental Medicine, 2009, Beauvais, DeannaLee M. et. al.

Receptor protein tyrosine phosphatase α activates Src-family kinases and controls integrin-mediated responses in fibroblasts
score: 3.1923653, Current Biology, 1999, Su, Jing; Muranjan, Madhavi; Sap, Jan

Molecular regulation of receptor tyrosine kinases in hematopoietic malignancies
score: 3.1923594, Gene, 2006, Correll, Pamela H.; Paulson, Robert F.; Wei, Xin

Control of integrin genes expression in the eye
score: 3.1920103, Progress in Retinal and Eye Research, 2007, Vigneault, François et. al.

Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques
score: 3.1919077, Current Biology, 1996, Sawai, Earl T. et. al.

Solution Structure of the Hdm2 C2H2C4 RING, a Domain Critical for Ubiquitination of p53
score: 3.1909924, Journal of Molecular Biology, 2006, Kostic, Milka et. al.

Cloning and characterization of the rat GALR1 galanin receptor from Rin14B insulinoma cells
score: 3.1904356, Molecular Brain Research, 1995, Parker, Eric M. et. al.

Assembly of the Truncated Immunoglobulin Heavy Chain Dμ into Antigen Receptor–Like Complexes in Pre-B Cells but Not in B Cells
score: 3.1904112, Immunity, 1996, Horne, Mary C; Roth, Patricia E; DeFranco, Anthony L

Molecular Networks in FGF Signaling: Flotillin-1 and Cbl-Associated Protein Compete for the Binding to Fibroblast Growth Factor Receptor Substrate 2
score: 3.1903929, PLoS ONE, 2012, Tomasovic, Ana; Traub, Stephanie; Tikkanen, Ritva

The Role of CD45 in Signal Transduction
score: 3.1900375, Advances in Immunology, 1997, Justement, Louis B.

Differential phosphorylation of mitogen-activated protein kinase families by epidermal growth factor and ultraviolet B irradiation in SV40-transformed human keratinocytes
score: 3.1899719, Journal of Dermatological Science, 2001, Nakamura, Satoshi et. al.

Role of mitogen-activated protein kinase kinase 4 in cancer.
score: 3.1897795, Oncogene, 2007, Whitmarsh, A J; Davis, R J

Dynamic Interplay betweenO-Glycosylation andO-Phosphorylation of Nucleocytoplasmic Proteins: A New Paradigm for Metabolic Control of Signal Transduction and Transcription
score: 3.1893987, Progress in Nucleic Acid Research and Molecular Biology, 2003, Kamemura, Kazuo; Hart, Gerald W

Dynamic Interplay between O-Glycosylation and O-Phosphorylation of Nucleocytoplasmic Proteins: A New Paradigm for Metabolic Control of Signal Transduction and Transcription
score: 3.1893987, Progress in Nucleic Acid Research and Molecular Biology, 2003, Kamemura, Kazuo; Hart, Gerald W

Eph receptors and ephrins: Regulators of guidance and assembly
score: 3.189274, International Review of Cytology, 2000, Wilkinson, David G.

Eph receptors and ephrins: Regulators of guidance and assembly
score: 3.189274, International Review of Cytology, 2000, Wilkinson, David G.

Eph receptors and ephrins: Regulators of guidance and assembly
score: 3.189274, International Review of Cytology, 2000, Wilkinson, David G.

Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit
score: 3.1885278, The Journal of Cell Biology, 1995,

A role for fasciclin II in the guidance of neuronal migration.
score: 3.1883822, Development (Cambridge, England), 1999, Wright, J W et. al.

Regulation of immune function by protein tyrosine phosphatases
score: 3.188356, Current Opinion in Immunology, 1995, Okumura, Meinoshin; Thomas, Matthew L.

Cell migration and the anatomic control of thymocyte precursor differentiation
score: 3.1880955, Seminars in Immunology, 2000, Prockop, Susan; Petrie, Howard T

Does Subunit Dissociation Necessarily Accompany the Activation of All Heterotrimeric G Proteins?
score: 3.1875104, Cellular Signalling, 1997, Rebois, R.Victor; Warner, Dennis R; Basi, Nirmal S

The neurotrophic action and signalling of epidermal growth factor
score: 3.1873349, Progress in Neurobiology, 1997, Yamada, Masashi; Ikeuchi, Toshihiko; Hatanaka, Hiroshi

Tumor Dormancy Induced by Downregulation of Urokinase Receptor in Human Carcinoma Involves Integrin and MAPK Signaling
score: 3.1872955, The Journal of Cell Biology, 1999, Ghiso, Julio A. Aguirre et. al.

Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor.
score: 3.1868302, Oncogene, 2001, Miyoshi-Akiyama, T et. al.

ADP-ribosylation factor 1 dependent clathrin-coat assembly on synthetic liposomes.
score: 3.186781, Proceedings of the National Academy of Sciences of the United States of America, 1999, Zhu, Y; Drake, M T; Kornfeld, S

Kidins220/ARMS regulates Rac1-dependent neurite outgrowth by direct interaction with the RhoGEF Trio.
score: 3.1863936, Journal of cell science, 2010, Neubrand, Veronika E et. al.

Contents
score: 3.1855367, Current Opinion in Genetics & Development, 1994,

A critical look at HLA-G
score: 3.1850899, Trends in Immunology, 2008, Apps, Richard; Gardner, Lucy; Moffett, Ashley

Phosphorylation of AKT: a Mutational Analysis
score: 3.1850413, Oncotarget, 2011, Hart, Jonathan R.; Vogt, Peter K.

The Ubiquitin-Interacting Motifs Target the Endocytic Adaptor Protein Epsin for Ubiquitination
score: 3.1830306, Current Biology, 2002, Oldham, Carla E. et. al.

The Ubiquitin-Interacting Motifs Target the Endocytic Adaptor Protein Epsin for Ubiquitination
score: 3.1830306, Current Biology, 2002, Oldham, Carla E. et. al.

Regulation of E2F: a family of transcription factors involved in proliferation control
score: 3.1829561, Gene, 1999, Black, Adrian R.; Azizkhan-Clifford, Jane

Type I Interferons in Host Defense
score: 3.1825169, Immunity, 2006, Stetson, Daniel B.; Medzhitov, Ruslan

Akt-dependent cell size regulation by the adhesion molecule on glia occurs independently of phosphatidylinositol 3-kinase and Rheb signaling.
score: 3.181441, Molecular and cellular biology, 2005, Scheidenhelm, Danielle K et. al.

A monoclonal antibody that causes the heterotrimeric G-protein G o to release its βγ subunits
score: 3.1807278, FEBS Letters, 1996, Yilla, Mamadi; Oleinick, Jonathan; Ploegh, Hidde L.

Mitochondria in innate immunity.
score: 3.1805818, EMBO reports, 2011, Arnoult, Damien et. al.

c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells.
score: 3.1802808, Molecular and cellular biology, 2000, Gregory, M A; Hann, S R

SPAP2, an Ig family receptor containing both ITIMs and ITAMs
score: 3.1793084, Biochemical and Biophysical Research Communications, 2002, Xu, Ming-jiang et. al.

no poles encodes a predicted E3 ubiquitin ligase required for early embryonic development of Drosophila.
score: 3.1790621, Development (Cambridge, England), 2009, Merkle, Julie A et. al.

Identification of Gemin5 as a Novel 7-Methylguanosine Cap-Binding Protein
score: 3.1775696, PLoS ONE, 2009, Bradrick, Shelton S.; Gromeier, Matthias

Toll-like receptor 9 mediates CpG-DNA signaling.
score: 3.1774882, Journal of leukocyte biology, 2002, Chuang, Tsung-Hsien et. al.

ChemR23, a putative chemoattractant receptor, is expressed in monocyte-derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV-1 strains.
score: 3.1768202, European journal of immunology, 1998, Samson, M et. al.

A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques
score: 3.1762796, The Journal of Cell Biology, 1992,

Multiple GTP-binding proteins regulate vesicular transport from the ER to Golgi membranes
score: 3.1762081, The Journal of Cell Biology, 1992,

Protein tyrosine phosphatases in signaling
score: 3.1748778, Current Opinion in Cell Biology, 1996, Streuli, Michel

Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.
score: 3.1745611, Proceedings of the National Academy of Sciences of the United States of America, 1995, Fujii, H et. al.

Guanylyl cyclases and signaling by cyclic GMP.
score: 3.174534, Pharmacological reviews, 2000, Lucas, K A et. al.

Caspase-3 inhibits growth in Saccharomyces cerevisiae without causing cell death 1 This work was supported by National Institutes of Health Grants 5P50 HL54881-02 (D.M.H.) and HL03174 (S.M.S.). 1
score: 3.1732855, FEBS Letters, 1999, Wright, Michael E. et. al.

CrkII induces serum response factor activation and cellular transformation through its function in Rho activation.
score: 3.1728481, Oncogene, 2003, Iwahara, Toshinori et. al.

The role of SLP-76 and LAT in lymphocyte development
score: 3.1728345, Current Opinion in Immunology, 2000, Pivniouk, Vadim I; Geha, Raif S

Human phospholipid scramblase 1 interacts with and regulates transactivation of HTLV-1 Tax
score: 3.1719906, Virology, 2012, Kusano, Shuichi; Eizuru, Yoshito

Meiotic lamin C2: the unique amino-terminal hexapeptide GNAEGR is essential for nuclear envelope association.
score: 3.171914, Proceedings of the National Academy of Sciences of the United States of America, 2000, Alsheimer, M et. al.

RNF24, a new TRPC interacting protein, causes the intracellular retention of TRPC
score: 3.1717488, Cell Calcium, 2008, Lussier, Marc P. et. al.

Differential influence of tyrosine residues of the common receptor β subunit on multiple signals induced by human GM-CSF
score: 3.1712461, The Journal of Allergy and Clinical Immunology, 1999, Itoh, Tohru; Liu, Rui; Arai, Ken-ichi; Watanabe, Sumiko

Regulation of Notch Signaling ViaO-Glucosylation-Chapter Seventeen:Insights from Drosophila Studies
score: 3.1711994, Methods in Enzymology, 2010, Lee, Tom V.; Takeuchi, Hideyuki; Jafar-Nejad, Hamed

E-Cadherin–dependent Growth Suppression is Mediated by the Cyclin-dependent Kinase Inhibitor p27 KIP1
score: 3.1709277, The Journal of Cell Biology, 1998, St. Croix, Brad et. al.

Skeletal dysplasia and defective chondrocyte differentiation by targeted overexpression of fibroblast growth factor 9 in transgenic mice.
score: 3.1707026, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1999, Garofalo, S et. al.

TCR subunit specificity of CTLA-4-mediated signaling.
score: 3.1706166, Journal of leukocyte biology, 2003, Siu, Eric; Carreno, Beatriz M; Madrenas, Joaquín

The tetratricopeptide repeat domains of rapsyn bind directly to cytoplasmic sequences of the muscle-specific kinase
score: 3.1702823, Neuroscience, 2006, Antolik, C.; Catino, D.H.; Resneck, W.G.; Bloch, R.J.

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro
score: 3.1701016, Current Biology, 1998, Alessi, Dario R. et. al.

NKp30 ligation induces rapid activation of the canonical NF-kappaB pathway in NK cells.
score: 3.1698812, Journal of immunology (Baltimore, Md. : 1950), 2007, Pandey, Rahul et. al.

Tyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase C gamma 1 activation in T cells.
score: 3.1698115, Molecular and cellular biology, 1996, Motto, D G; Musci, M A; Ross, S E; Koretzky, G A

Glycosaminoglycan affinity of the complete fibroblast growth factor family
score: 3.1694982, BBA - General Subjects, 2009, Asada, Masahiro et. al.

Activation of JAK2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland explants.
score: 3.1682746, Proceedings of the National Academy of Sciences of the United States of America, 1994, Campbell, G S et. al.